{"id":"https://openalex.org/W2053685994","doi":"https://doi.org/10.1007/s10827-008-0100-z","title":"A computational modelling approach to investigate different targets in deep brain stimulation for Parkinson\u2019s disease","display_name":"A computational modelling approach to investigate different targets in deep brain stimulation for Parkinson\u2019s disease","publication_year":2008,"publication_date":"2008-06-13","ids":{"openalex":"https://openalex.org/W2053685994","doi":"https://doi.org/10.1007/s10827-008-0100-z","mag":"2053685994","pmid":"https://pubmed.ncbi.nlm.nih.gov/18553128"},"language":"en","primary_location":{"id":"doi:10.1007/s10827-008-0100-z","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10827-008-0100-z","pdf_url":null,"source":{"id":"https://openalex.org/S27455496","display_name":"Journal of Computational Neuroscience","issn_l":"0929-5313","issn":["0929-5313","1573-6873"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Computational Neuroscience","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5044210571","display_name":"Marco Pirini","orcid":null},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Marco Pirini","raw_affiliation_strings":["Biomedical Engineering Unit, Department of Electronics, Computer Science & Systems, Universit\u00e0 di Bologna, Viale Risorgimento 2, 40136, Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Unit, Department of Electronics, Computer Science & Systems, Universit\u00e0 di Bologna, Viale Risorgimento 2, 40136, Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054649176","display_name":"Laura Rocchi","orcid":"https://orcid.org/0000-0002-2444-1359"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Laura Rocchi","raw_affiliation_strings":["Biomedical Engineering Unit, Department of Electronics, Computer Science & Systems, Universit\u00e0 di Bologna, Viale Risorgimento 2, 40136, Bologna, Italy","Biomedical Engineering Unit, Department of Electronics, Computer Science & Systems, Universit\u00e0 di Bologna, Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Unit, Department of Electronics, Computer Science & Systems, Universit\u00e0 di Bologna, Viale Risorgimento 2, 40136, Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]},{"raw_affiliation_string":"Biomedical Engineering Unit, Department of Electronics, Computer Science & Systems, Universit\u00e0 di Bologna, Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013003515","display_name":"Mariachiara Sensi","orcid":"https://orcid.org/0000-0002-6434-5433"},"institutions":[{"id":"https://openalex.org/I201324441","display_name":"University of Ferrara","ror":"https://ror.org/041zkgm14","country_code":"IT","type":"education","lineage":["https://openalex.org/I201324441"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mariachiara Sensi","raw_affiliation_strings":["Department of Neuroscience, S. Anna University Hospital of Ferrara, Ferrara, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, S. Anna University Hospital of Ferrara, Ferrara, Italy","institution_ids":["https://openalex.org/I201324441"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012299262","display_name":"Lorenzo Chiari","orcid":"https://orcid.org/0000-0002-2318-4370"},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Lorenzo Chiari","raw_affiliation_strings":["Biomedical Engineering Unit, Department of Electronics, Computer Science & Systems, Universit\u00e0 di Bologna, Viale Risorgimento 2, 40136, Bologna, Italy","Biomedical Engineering Unit, Department of Electronics, Computer Science & Systems, Universit\u00e0 di Bologna, Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biomedical Engineering Unit, Department of Electronics, Computer Science & Systems, Universit\u00e0 di Bologna, Viale Risorgimento 2, 40136, Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]},{"raw_affiliation_string":"Biomedical Engineering Unit, Department of Electronics, Computer Science & Systems, Universit\u00e0 di Bologna, Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5012299262"],"corresponding_institution_ids":["https://openalex.org/I9360294"],"apc_list":{"value":3390,"currency":"USD","value_usd":3390},"apc_paid":null,"fwci":1.9925,"has_fulltext":false,"cited_by_count":72,"citation_normalized_percentile":{"value":0.8587167,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"26","issue":"1","first_page":"91","last_page":"107"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11601","display_name":"Neuroscience and Neural Engineering","score":0.9871000051498413,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/deep-brain-stimulation","display_name":"Deep brain stimulation","score":0.8557106256484985},{"id":"https://openalex.org/keywords/parkinsons-disease","display_name":"Parkinson's disease","score":0.7885650396347046},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.7039139270782471},{"id":"https://openalex.org/keywords/theory-of-computation","display_name":"Theory of computation","score":0.5435022115707397},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.5151135325431824},{"id":"https://openalex.org/keywords/computational-model","display_name":"Computational model","score":0.5006093978881836},{"id":"https://openalex.org/keywords/brain-stimulation","display_name":"Brain stimulation","score":0.46539032459259033},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.4337165355682373},{"id":"https://openalex.org/keywords/cognitive-science","display_name":"Cognitive science","score":0.41673707962036133},{"id":"https://openalex.org/keywords/stimulation","display_name":"Stimulation","score":0.40337568521499634},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3364045023918152},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.3156129717826843},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.30851101875305176},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.09354612231254578},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.08448240160942078}],"concepts":[{"id":"https://openalex.org/C2778542668","wikidata":"https://www.wikidata.org/wiki/Q618076","display_name":"Deep brain stimulation","level":4,"score":0.8557106256484985},{"id":"https://openalex.org/C2779734285","wikidata":"https://www.wikidata.org/wiki/Q11085","display_name":"Parkinson's disease","level":3,"score":0.7885650396347046},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7039139270782471},{"id":"https://openalex.org/C24858836","wikidata":"https://www.wikidata.org/wiki/Q844718","display_name":"Theory of computation","level":2,"score":0.5435022115707397},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5151135325431824},{"id":"https://openalex.org/C66024118","wikidata":"https://www.wikidata.org/wiki/Q1122506","display_name":"Computational model","level":2,"score":0.5006093978881836},{"id":"https://openalex.org/C2985799443","wikidata":"https://www.wikidata.org/wiki/Q4955838","display_name":"Brain stimulation","level":3,"score":0.46539032459259033},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4337165355682373},{"id":"https://openalex.org/C188147891","wikidata":"https://www.wikidata.org/wiki/Q147638","display_name":"Cognitive science","level":1,"score":0.41673707962036133},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.40337568521499634},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3364045023918152},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3156129717826843},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.30851101875305176},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.09354612231254578},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.08448240160942078}],"mesh":[{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000200","descriptor_name":"Action Potentials","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005917","descriptor_name":"Globus Pallidus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005917","descriptor_name":"Globus Pallidus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D005917","descriptor_name":"Globus Pallidus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D009434","descriptor_name":"Neural Pathways","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D010300","descriptor_name":"Parkinson Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D013788","descriptor_name":"Thalamus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D013788","descriptor_name":"Thalamus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D013788","descriptor_name":"Thalamus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020531","descriptor_name":"Subthalamic Nucleus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020531","descriptor_name":"Subthalamic Nucleus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D020531","descriptor_name":"Subthalamic Nucleus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D046690","descriptor_name":"Deep Brain Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D046690","descriptor_name":"Deep Brain Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D046690","descriptor_name":"Deep Brain Stimulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s10827-008-0100-z","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10827-008-0100-z","pdf_url":null,"source":{"id":"https://openalex.org/S27455496","display_name":"Journal of Computational Neuroscience","issn_l":"0929-5313","issn":["0929-5313","1573-6873"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Computational Neuroscience","raw_type":"journal-article"},{"id":"pmid:18553128","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18553128","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of computational neuroscience","raw_type":null},{"id":"pmh:oai:cris.unibo.it:11585/73619","is_oa":false,"landing_page_url":"http://hdl.handle.net/11585/73619","pdf_url":null,"source":{"id":"https://openalex.org/S4306402579","display_name":"Archivio istituzionale della ricerca (Alma Mater Studiorum Universit\u00e0 di Bologna)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210117483","host_organization_name":"Istituto di Ematologia di Bologna","host_organization_lineage":["https://openalex.org/I4210117483"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.5199999809265137}],"awards":[],"funders":[{"id":"https://openalex.org/F4320309374","display_name":"Ohio State University","ror":"https://ror.org/00rs6vg23"},{"id":"https://openalex.org/F4320310174","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305"},{"id":"https://openalex.org/F4320323553","display_name":"Universit\u00e0 di Bologna","ror":"https://ror.org/01111rn36"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W1510554078","https://openalex.org/W1592587113","https://openalex.org/W1771226674","https://openalex.org/W1832682301","https://openalex.org/W1894755029","https://openalex.org/W1963735224","https://openalex.org/W1970994015","https://openalex.org/W1976904670","https://openalex.org/W1982827121","https://openalex.org/W1985174354","https://openalex.org/W1991532669","https://openalex.org/W2004153344","https://openalex.org/W2005269174","https://openalex.org/W2018607331","https://openalex.org/W2020213455","https://openalex.org/W2023890073","https://openalex.org/W2024486693","https://openalex.org/W2025359853","https://openalex.org/W2026823531","https://openalex.org/W2029754211","https://openalex.org/W2034744975","https://openalex.org/W2035589773","https://openalex.org/W2047384561","https://openalex.org/W2049483623","https://openalex.org/W2055550792","https://openalex.org/W2056020273","https://openalex.org/W2065147517","https://openalex.org/W2067135361","https://openalex.org/W2085376923","https://openalex.org/W2089036931","https://openalex.org/W2089191479","https://openalex.org/W2101919900","https://openalex.org/W2102670529","https://openalex.org/W2103670858","https://openalex.org/W2107199167","https://openalex.org/W2110065186","https://openalex.org/W2119329187","https://openalex.org/W2123208606","https://openalex.org/W2124227727","https://openalex.org/W2136554543","https://openalex.org/W2140684369","https://openalex.org/W2141405085","https://openalex.org/W2143199409","https://openalex.org/W2145646909","https://openalex.org/W2146460333","https://openalex.org/W2149661045","https://openalex.org/W2157881799","https://openalex.org/W2159447846","https://openalex.org/W2160017783","https://openalex.org/W2161438629","https://openalex.org/W2169247253","https://openalex.org/W2413874424","https://openalex.org/W4306148854"],"related_works":["https://openalex.org/W622158969","https://openalex.org/W2518873333","https://openalex.org/W2114827170","https://openalex.org/W4386070499","https://openalex.org/W2414205034","https://openalex.org/W2914511819","https://openalex.org/W2771365127","https://openalex.org/W2884613167","https://openalex.org/W2917051815","https://openalex.org/W2390600672"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":6}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}