{"id":"https://openalex.org/W4402489852","doi":"https://doi.org/10.1007/s10796-024-10536-4","title":"A Conceptual Framework for Digital Twin in Healthcare: Evidence from a Systematic Meta-Review","display_name":"A Conceptual Framework for Digital Twin in Healthcare: Evidence from a Systematic Meta-Review","publication_year":2024,"publication_date":"2024-09-12","ids":{"openalex":"https://openalex.org/W4402489852","doi":"https://doi.org/10.1007/s10796-024-10536-4"},"language":"en","primary_location":{"id":"doi:10.1007/s10796-024-10536-4","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10796-024-10536-4","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10796-024-10536-4.pdf","source":{"id":"https://openalex.org/S181659395","display_name":"Information Systems Frontiers","issn_l":"1387-3326","issn":["1387-3326","1572-9419"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Information Systems Frontiers","raw_type":"journal-article"},"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s10796-024-10536-4.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050007640","display_name":"Giulia Pellegrino","orcid":"https://orcid.org/0009-0009-8227-5393"},"institutions":[{"id":"https://openalex.org/I142910587","display_name":"University of Salento","ror":"https://ror.org/03fc1k060","country_code":"IT","type":"education","lineage":["https://openalex.org/I142910587"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Giulia Pellegrino","raw_affiliation_strings":["Department of Engineering for Innovation, University of Salento, Lecce, Italy"],"raw_orcid":"https://orcid.org/0009-0009-8227-5393","affiliations":[{"raw_affiliation_string":"Department of Engineering for Innovation, University of Salento, Lecce, Italy","institution_ids":["https://openalex.org/I142910587"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021131220","display_name":"Massimiliano Gervasi","orcid":"https://orcid.org/0000-0001-6114-1454"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Massimiliano Gervasi","raw_affiliation_strings":["Lecce, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lecce, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011088707","display_name":"Mario Angelelli","orcid":"https://orcid.org/0000-0002-9782-7834"},"institutions":[{"id":"https://openalex.org/I142910587","display_name":"University of Salento","ror":"https://ror.org/03fc1k060","country_code":"IT","type":"education","lineage":["https://openalex.org/I142910587"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Mario Angelelli","raw_affiliation_strings":["Department of Human and Social Sciences, University of Salento, Lecce, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human and Social Sciences, University of Salento, Lecce, Italy","institution_ids":["https://openalex.org/I142910587"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024787852","display_name":"Angelo Corallo","orcid":"https://orcid.org/0000-0001-5216-5366"},"institutions":[{"id":"https://openalex.org/I142910587","display_name":"University of Salento","ror":"https://ror.org/03fc1k060","country_code":"IT","type":"education","lineage":["https://openalex.org/I142910587"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Angelo Corallo","raw_affiliation_strings":["Department of Experimental Medicine, University of Salento, Lecce, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Medicine, University of Salento, Lecce, Italy","institution_ids":["https://openalex.org/I142910587"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5050007640"],"corresponding_institution_ids":["https://openalex.org/I142910587"],"apc_list":{"value":2890,"currency":"USD","value_usd":2890},"apc_paid":{"value":2890,"currency":"USD","value_usd":2890},"fwci":10.7066,"has_fulltext":true,"cited_by_count":49,"citation_normalized_percentile":{"value":0.98905276,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":100},"biblio":{"volume":"27","issue":"1","first_page":"7","last_page":"32"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10763","display_name":"Digital Transformation in Industry","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/2209","display_name":"Industrial and Manufacturing Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10763","display_name":"Digital Transformation in Industry","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/2209","display_name":"Industrial and Manufacturing Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/health-care","display_name":"Health care","score":0.5966431498527527},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5380792617797852},{"id":"https://openalex.org/keywords/conceptual-framework","display_name":"Conceptual framework","score":0.4794115722179413},{"id":"https://openalex.org/keywords/systematic-review","display_name":"Systematic review","score":0.4632367491722107},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.41274720430374146},{"id":"https://openalex.org/keywords/knowledge-management","display_name":"Knowledge management","score":0.40824058651924133},{"id":"https://openalex.org/keywords/medline","display_name":"MEDLINE","score":0.29418033361434937},{"id":"https://openalex.org/keywords/sociology","display_name":"Sociology","score":0.1765519380569458},{"id":"https://openalex.org/keywords/political-science","display_name":"Political science","score":0.1400616466999054},{"id":"https://openalex.org/keywords/social-science","display_name":"Social science","score":0.07891428470611572}],"concepts":[{"id":"https://openalex.org/C160735492","wikidata":"https://www.wikidata.org/wiki/Q31207","display_name":"Health care","level":2,"score":0.5966431498527527},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5380792617797852},{"id":"https://openalex.org/C14224292","wikidata":"https://www.wikidata.org/wiki/Q13600188","display_name":"Conceptual framework","level":2,"score":0.4794115722179413},{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.4632367491722107},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.41274720430374146},{"id":"https://openalex.org/C56739046","wikidata":"https://www.wikidata.org/wiki/Q192060","display_name":"Knowledge management","level":1,"score":0.40824058651924133},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.29418033361434937},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.1765519380569458},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.1400616466999054},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.07891428470611572},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/s10796-024-10536-4","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10796-024-10536-4","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10796-024-10536-4.pdf","source":{"id":"https://openalex.org/S181659395","display_name":"Information Systems Frontiers","issn_l":"1387-3326","issn":["1387-3326","1572-9419"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Information Systems Frontiers","raw_type":"journal-article"},{"id":"pmh:oai:RePEc:spr:infosf:v:27:y:2025:i:1:d:10.1007_s10796-024-10536-4","is_oa":false,"landing_page_url":"http://link.springer.com/10.1007/s10796-024-10536-4","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"doi:10.1007/s10796-024-10536-4","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10796-024-10536-4","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10796-024-10536-4.pdf","source":{"id":"https://openalex.org/S181659395","display_name":"Information Systems Frontiers","issn_l":"1387-3326","issn":["1387-3326","1572-9419"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Information Systems Frontiers","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320310281","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666"},{"id":"https://openalex.org/F4320320006","display_name":"Royal Society","ror":"https://ror.org/03wnrjx87"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4402489852.pdf","grobid_xml":"https://content.openalex.org/works/W4402489852.grobid-xml"},"referenced_works_count":101,"referenced_works":["https://openalex.org/W1495670988","https://openalex.org/W1579476183","https://openalex.org/W1588485088","https://openalex.org/W2041685491","https://openalex.org/W2043360969","https://openalex.org/W2069178071","https://openalex.org/W2079283960","https://openalex.org/W2080640610","https://openalex.org/W2100379340","https://openalex.org/W2108366027","https://openalex.org/W2296158452","https://openalex.org/W2395492686","https://openalex.org/W2518003110","https://openalex.org/W2557377367","https://openalex.org/W2597150627","https://openalex.org/W2754430621","https://openalex.org/W2794230447","https://openalex.org/W2808266815","https://openalex.org/W2890418156","https://openalex.org/W2890904471","https://openalex.org/W2909072371","https://openalex.org/W2941876953","https://openalex.org/W2955790054","https://openalex.org/W2964523010","https://openalex.org/W2966928317","https://openalex.org/W2969173326","https://openalex.org/W2970578259","https://openalex.org/W2972764124","https://openalex.org/W2982936646","https://openalex.org/W2988359971","https://openalex.org/W2989925413","https://openalex.org/W3010152544","https://openalex.org/W3044376418","https://openalex.org/W3048296440","https://openalex.org/W3097471692","https://openalex.org/W3102042805","https://openalex.org/W3109559253","https://openalex.org/W3128842718","https://openalex.org/W3132985895","https://openalex.org/W3147181238","https://openalex.org/W3154701018","https://openalex.org/W3159064895","https://openalex.org/W3171674920","https://openalex.org/W3184569878","https://openalex.org/W3187908441","https://openalex.org/W3195402235","https://openalex.org/W3200045630","https://openalex.org/W3205912730","https://openalex.org/W3209398723","https://openalex.org/W3216483517","https://openalex.org/W3216898476","https://openalex.org/W3217506920","https://openalex.org/W4206453649","https://openalex.org/W4206842007","https://openalex.org/W4210425672","https://openalex.org/W4220710261","https://openalex.org/W4220831070","https://openalex.org/W4220925903","https://openalex.org/W4220941181","https://openalex.org/W4225966689","https://openalex.org/W4226517416","https://openalex.org/W4280498362","https://openalex.org/W4281564688","https://openalex.org/W4283204398","https://openalex.org/W4285098908","https://openalex.org/W4285390111","https://openalex.org/W4285891733","https://openalex.org/W4288455776","https://openalex.org/W4289175114","https://openalex.org/W4292290896","https://openalex.org/W4293109418","https://openalex.org/W4293210198","https://openalex.org/W4295182973","https://openalex.org/W4296518294","https://openalex.org/W4296613139","https://openalex.org/W4311796459","https://openalex.org/W4313527145","https://openalex.org/W4313590025","https://openalex.org/W4316039053","https://openalex.org/W4366000108","https://openalex.org/W4366818813","https://openalex.org/W4376256941","https://openalex.org/W4378745639","https://openalex.org/W4381705805","https://openalex.org/W4381952081","https://openalex.org/W4383552219","https://openalex.org/W4384434838","https://openalex.org/W4384933377","https://openalex.org/W4385895844","https://openalex.org/W4386432501","https://openalex.org/W4386432623","https://openalex.org/W4386517498","https://openalex.org/W4386706942","https://openalex.org/W4388696529","https://openalex.org/W4392051078","https://openalex.org/W4392469902","https://openalex.org/W4395673736","https://openalex.org/W4399303221","https://openalex.org/W4401083203","https://openalex.org/W6603327141","https://openalex.org/W6722336247"],"related_works":["https://openalex.org/W2395691387","https://openalex.org/W2792383399","https://openalex.org/W3024289321","https://openalex.org/W2766255174","https://openalex.org/W4200400515","https://openalex.org/W2938724434","https://openalex.org/W4200615155","https://openalex.org/W4320717566","https://openalex.org/W4322495751","https://openalex.org/W1499464851"],"abstract_inverted_index":{"Abstract":[0],"Digital":[1],"Twin":[2],"(DT)":[3],"technology":[4],"monitors,":[5],"simulates,":[6],"optimizes,":[7],"models,":[8],"and":[9,43,51,103,139],"predicts":[10],"the":[11,61,70,78,81,100,114,124,136],"behavior":[12],"of":[13,34,40,63,73,90,141],"physical":[14],"entities.":[15],"Healthcare":[16],"is":[17,55],"a":[18,22,37,56,64,144],"significant":[19],"domain":[20],"where":[21],"DT":[23],"can":[24,47,134],"be":[25],"functional":[26],"for":[27,147],"multiple":[28],"purposes.":[29],"However,":[30],"these":[31,120],"diverse":[32],"uses":[33],"DTs":[35,74,108],"need":[36],"clear":[38],"understanding":[39],"both":[41],"general":[42],"specific":[44],"aspects":[45,105,121],"that":[46,58,106],"affect":[48],"their":[49,148],"adoption":[50],"integration.":[52],"This":[53],"paper":[54],"meta-review":[57,82],"leads":[59],"to":[60,68,122],"development":[62],"conceptual":[65],"framework":[66,133],"designed":[67],"support":[69],"high-level":[71],"evaluation":[72],"in":[75,109,128],"healthcare.":[76,110],"Using":[77],"PRISMA":[79],"methodology,":[80],"synthesizes":[83],"insights":[84],"from":[85],"20":[86],"selected":[87],"reviews":[88],"out":[89],"1,075":[91],"studies.":[92],"Based":[93],"on":[94],"this":[95],"comprehensive":[96],"analysis,":[97],"we":[98,112],"extract":[99],"functional,":[101],"technological,":[102],"operational":[104],"characterize":[107],"Additionally,":[111],"examine":[113],"structural":[115],"(e.g.,":[116],"hierarchical)":[117],"relationships":[118],"among":[119],"address":[123],"various":[125],"complexity":[126],"scales":[127],"digital":[129],"health.":[130],"The":[131],"resulting":[132],"promote":[135],"effective":[137],"design":[138],"implementation":[140],"DTs,":[142],"offering":[143],"structured":[145],"approach":[146],"assessment.":[149]},"counts_by_year":[{"year":2026,"cited_by_count":23},{"year":2025,"cited_by_count":25},{"year":2024,"cited_by_count":1}],"updated_date":"2026-07-23T08:03:31.855105","created_date":"2025-10-10T00:00:00"}