{"id":"https://openalex.org/W4405653627","doi":"https://doi.org/10.1007/s10462-024-11041-5","title":"Applications of deep learning in Alzheimer\u2019s disease: a systematic literature review of current trends, methodologies, challenges, innovations, and future directions","display_name":"Applications of deep learning in Alzheimer\u2019s disease: a systematic literature review of current trends, methodologies, challenges, innovations, and future directions","publication_year":2024,"publication_date":"2024-12-20","ids":{"openalex":"https://openalex.org/W4405653627","doi":"https://doi.org/10.1007/s10462-024-11041-5"},"language":"en","primary_location":{"id":"doi:10.1007/s10462-024-11041-5","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10462-024-11041-5","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10462-024-11041-5.pdf","source":{"id":"https://openalex.org/S122814990","display_name":"Artificial Intelligence Review","issn_l":"0269-2821","issn":["0269-2821","1573-7462"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Artificial Intelligence Review","raw_type":"journal-article"},"type":"review","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s10462-024-11041-5.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5063253200","display_name":"Shiva Toumaj","orcid":"https://orcid.org/0000-0002-4828-9427"},"institutions":[{"id":"https://openalex.org/I38476204","display_name":"Urmia University","ror":"https://ror.org/032fk0x53","country_code":"IR","type":"education","lineage":["https://openalex.org/I38476204"]},{"id":"https://openalex.org/I4391767979","display_name":"Urmia University of Medical Sciences","ror":"https://ror.org/03jbsdf87","country_code":null,"type":"education","lineage":["https://openalex.org/I4391767979"]}],"countries":["IR"],"is_corresponding":false,"raw_author_name":"Shiva Toumaj","raw_affiliation_strings":["Urmia University of Medical Sciences, Urmia, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Urmia University of Medical Sciences, Urmia, Iran","institution_ids":["https://openalex.org/I38476204","https://openalex.org/I4391767979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086695777","display_name":"Arash Heidari","orcid":"https://orcid.org/0000-0003-4279-8551"},"institutions":[{"id":"https://openalex.org/I1293555014","display_name":"Islamic Azad University of Tabriz","ror":"https://ror.org/04hnf9a51","country_code":"IR","type":"education","lineage":["https://openalex.org/I110525433","https://openalex.org/I1293555014"]},{"id":"https://openalex.org/I4387153143","display_name":"Atlas \u00dcniversitesi","ror":"https://ror.org/02jqzm779","country_code":null,"type":"education","lineage":["https://openalex.org/I4387153143"]},{"id":"https://openalex.org/I50627504","display_name":"Istanbul Arel University","ror":"https://ror.org/03natay60","country_code":"TR","type":"education","lineage":["https://openalex.org/I50627504"]}],"countries":["IR","TR"],"is_corresponding":true,"raw_author_name":"Arash Heidari","raw_affiliation_strings":["Department of Computer Engineering, Faculty of Engineering and Natural Science, \u0130stanbul Atlas University, Istanbul, T\u00fcrkiye","Department of Computer Engineering, Tabriz Branch, Islamic Azad University, Tabriz, Iran"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Engineering, Faculty of Engineering and Natural Science, \u0130stanbul Atlas University, Istanbul, T\u00fcrkiye","institution_ids":["https://openalex.org/I4387153143","https://openalex.org/I50627504"]},{"raw_affiliation_string":"Department of Computer Engineering, Tabriz Branch, Islamic Azad University, Tabriz, Iran","institution_ids":["https://openalex.org/I1293555014"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5093448842","display_name":"Reza Shahhosseini","orcid":null},"institutions":[{"id":"https://openalex.org/I3125470973","display_name":"Istanbul Medipol University","ror":"https://ror.org/037jwzz50","country_code":"TR","type":"education","lineage":["https://openalex.org/I3125470973"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Reza Shahhosseini","raw_affiliation_strings":["Istanbul Medipol University, Istanbul, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Istanbul Medipol University, Istanbul, Turkey","institution_ids":["https://openalex.org/I3125470973"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007907571","display_name":"Nima Jafari Navimipour","orcid":"https://orcid.org/0000-0002-5514-5536"},"institutions":[{"id":"https://openalex.org/I132286405","display_name":"Kadir Has University","ror":"https://ror.org/03zzckc47","country_code":"TR","type":"education","lineage":["https://openalex.org/I132286405"]},{"id":"https://openalex.org/I3130874397","display_name":"Western Caspian University","ror":"https://ror.org/05cgtjz78","country_code":"AZ","type":"education","lineage":["https://openalex.org/I3130874397"]},{"id":"https://openalex.org/I75357094","display_name":"National Yunlin University of Science and Technology","ror":"https://ror.org/04qkq2m54","country_code":"TW","type":"education","lineage":["https://openalex.org/I75357094"]}],"countries":["AZ","TR","TW"],"is_corresponding":false,"raw_author_name":"Nima Jafari Navimipour","raw_affiliation_strings":["Department of Computer Engineering, Faculty of Engineering and Natural Sciences, Kadir Has University, Istanbul, Turkey","Future Technology Research Center, National Yunlin University of Science and Technology, Douliou, 64002, Yunlin, Taiwan","Research Center of High Technologies and Innovative Engineering, Western Caspian University, Baku, Azerbaijan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computer Engineering, Faculty of Engineering and Natural Sciences, Kadir Has University, Istanbul, Turkey","institution_ids":["https://openalex.org/I132286405"]},{"raw_affiliation_string":"Future Technology Research Center, National Yunlin University of Science and Technology, Douliou, 64002, Yunlin, Taiwan","institution_ids":["https://openalex.org/I75357094"]},{"raw_affiliation_string":"Research Center of High Technologies and Innovative Engineering, Western Caspian University, Baku, Azerbaijan","institution_ids":["https://openalex.org/I3130874397"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5086695777"],"corresponding_institution_ids":["https://openalex.org/I1293555014","https://openalex.org/I4387153143","https://openalex.org/I50627504"],"apc_list":{"value":3090,"currency":"USD","value_usd":3090},"apc_paid":{"value":3090,"currency":"USD","value_usd":3090},"fwci":4.8019,"has_fulltext":true,"cited_by_count":64,"citation_normalized_percentile":{"value":0.95493562,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":99,"max":100},"biblio":{"volume":"58","issue":"2","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9898999929428101,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9898999929428101,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9879999756813049,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12702","display_name":"Brain Tumor Detection and Classification","score":0.9782000184059143,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6701117753982544},{"id":"https://openalex.org/keywords/current","display_name":"Current (fluid)","score":0.6210025548934937},{"id":"https://openalex.org/keywords/systematic-review","display_name":"Systematic review","score":0.5492029190063477},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.41571933031082153},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3612912893295288},{"id":"https://openalex.org/keywords/medline","display_name":"MEDLINE","score":0.18869656324386597},{"id":"https://openalex.org/keywords/political-science","display_name":"Political science","score":0.08847656846046448},{"id":"https://openalex.org/keywords/oceanography","display_name":"Oceanography","score":0.055387943983078},{"id":"https://openalex.org/keywords/geology","display_name":"Geology","score":0.05422070622444153}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6701117753982544},{"id":"https://openalex.org/C148043351","wikidata":"https://www.wikidata.org/wiki/Q4456944","display_name":"Current (fluid)","level":2,"score":0.6210025548934937},{"id":"https://openalex.org/C189708586","wikidata":"https://www.wikidata.org/wiki/Q1504425","display_name":"Systematic review","level":3,"score":0.5492029190063477},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.41571933031082153},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3612912893295288},{"id":"https://openalex.org/C2779473830","wikidata":"https://www.wikidata.org/wiki/Q1540899","display_name":"MEDLINE","level":2,"score":0.18869656324386597},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.08847656846046448},{"id":"https://openalex.org/C111368507","wikidata":"https://www.wikidata.org/wiki/Q43518","display_name":"Oceanography","level":1,"score":0.055387943983078},{"id":"https://openalex.org/C127313418","wikidata":"https://www.wikidata.org/wiki/Q1069","display_name":"Geology","level":0,"score":0.05422070622444153},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/s10462-024-11041-5","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10462-024-11041-5","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10462-024-11041-5.pdf","source":{"id":"https://openalex.org/S122814990","display_name":"Artificial Intelligence Review","issn_l":"0269-2821","issn":["0269-2821","1573-7462"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Artificial Intelligence Review","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.1007/s10462-024-11041-5","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s10462-024-11041-5","pdf_url":"https://link.springer.com/content/pdf/10.1007/s10462-024-11041-5.pdf","source":{"id":"https://openalex.org/S122814990","display_name":"Artificial Intelligence Review","issn_l":"0269-2821","issn":["0269-2821","1573-7462"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Artificial Intelligence Review","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4405653627.pdf","grobid_xml":"https://content.openalex.org/works/W4405653627.grobid-xml"},"referenced_works_count":81,"referenced_works":["https://openalex.org/W3040248281","https://openalex.org/W3041975743","https://openalex.org/W3047901047","https://openalex.org/W3122625233","https://openalex.org/W3125401821","https://openalex.org/W3136333197","https://openalex.org/W3158891634","https://openalex.org/W3162048269","https://openalex.org/W3168517739","https://openalex.org/W4200554941","https://openalex.org/W4205309705","https://openalex.org/W4205619992","https://openalex.org/W4210492407","https://openalex.org/W4214825821","https://openalex.org/W4291008360","https://openalex.org/W4296800293","https://openalex.org/W4306742555","https://openalex.org/W4307565777","https://openalex.org/W4307657938","https://openalex.org/W4308404758","https://openalex.org/W4310136297","https://openalex.org/W4310701303","https://openalex.org/W4312247626","https://openalex.org/W4312569488","https://openalex.org/W4313458172","https://openalex.org/W4319321475","https://openalex.org/W4319964312","https://openalex.org/W4323534860","https://openalex.org/W4360798171","https://openalex.org/W4361004505","https://openalex.org/W4362696487","https://openalex.org/W4362704266","https://openalex.org/W4367174198","https://openalex.org/W4380369812","https://openalex.org/W4381384569","https://openalex.org/W4383068620","https://openalex.org/W4384029030","https://openalex.org/W4384038592","https://openalex.org/W4385271681","https://openalex.org/W4385376417","https://openalex.org/W4385406307","https://openalex.org/W4385431294","https://openalex.org/W4385501660","https://openalex.org/W4386068592","https://openalex.org/W4386078237","https://openalex.org/W4386262510","https://openalex.org/W4386571345","https://openalex.org/W4386629434","https://openalex.org/W4386905721","https://openalex.org/W4387131137","https://openalex.org/W4387139307","https://openalex.org/W4387140453","https://openalex.org/W4387247665","https://openalex.org/W4387408166","https://openalex.org/W4387878304","https://openalex.org/W4388261524","https://openalex.org/W4388490630","https://openalex.org/W4388642353","https://openalex.org/W4388665787","https://openalex.org/W4389265315","https://openalex.org/W4389286838","https://openalex.org/W4389513461","https://openalex.org/W4389549989","https://openalex.org/W4389556156","https://openalex.org/W4389671997","https://openalex.org/W4389954667","https://openalex.org/W4389962829","https://openalex.org/W4390420559","https://openalex.org/W4390590484","https://openalex.org/W4390609916","https://openalex.org/W4390673894","https://openalex.org/W4390777660","https://openalex.org/W4391046808","https://openalex.org/W4391363942","https://openalex.org/W4391509766","https://openalex.org/W4391573084","https://openalex.org/W4391690822","https://openalex.org/W4391848960","https://openalex.org/W4391884291","https://openalex.org/W4392024572","https://openalex.org/W4392194338"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W2899084033","https://openalex.org/W2748952813","https://openalex.org/W2390279801","https://openalex.org/W4391913857","https://openalex.org/W2358668433","https://openalex.org/W4396701345","https://openalex.org/W2376932109","https://openalex.org/W2001405890","https://openalex.org/W4396696052"],"abstract_inverted_index":{"Alzheimer\u2019s":[0,90],"Disease":[1],"(AD)":[2],"constitutes":[3],"a":[4],"significant":[5],"global":[6],"health":[7],"issue.":[8],"In":[9],"the":[10,81,94,178,220,228],"next":[11],"40":[12],"years,":[13],"it":[14,44],"is":[15,45,141,156],"expected":[16],"to":[17,36,46,63,118,182],"affect":[18],"106":[19],"million":[20],"people.":[21],"Although":[22],"more":[23,25,60,62,197,215],"and":[24,48,61,75,104,113,129,154,169,190,203,217],"people":[26],"are":[27,31,96,147,172],"getting":[28],"AD,":[29],"there":[30],"still":[32],"no":[33],"effective":[34],"drugs":[35],"treat":[37,49],"it.":[38],"Insightful":[39],"information":[40],"about":[41,86],"how":[42,119,125,130],"important":[43,139],"find":[47],"AD":[50,152,224],"quickly.":[51],"Recently,":[52],"Deep":[53],"Learning":[54],"(DL)":[55],"techniques":[56],"have":[57,84],"been":[58],"used":[59,134,150,159],"diagnose":[64],"AD.":[65],"They":[66],"claim":[67],"better":[68,200],"accuracy":[69],"in":[70,135,177,227],"drug":[71,101],"reuse,":[72,102],"medication":[73],"recognition,":[74],"labeling.":[76],"This":[77,184],"essay":[78],"meticulously":[79],"examines":[80,187],"works":[82],"that":[83,142,195,206],"talked":[85],"using":[87],"DL":[88,161],"with":[89],"disease.":[91],"Some":[92,163],"of":[93,222],"methods":[95,189],"Natural":[97],"Language":[98],"Processing":[99],"(NLP),":[100],"classification,":[103],"identification.":[105],"Concerning":[106],"these":[107],"methods,":[108],"we":[109],"examine":[110],"their":[111],"pros":[112],"cons,":[114],"paying":[115],"special":[116],"attention":[117],"easily":[120],"they":[121,127,131],"can":[122,132,207],"be":[123,133,208],"explained,":[124],"safe":[126],"are,":[128],"medical":[136],"situations.":[137],"One":[138],"finding":[140],"Convolutional":[143],"Neural":[144],"Networks":[145],"(CNNs)":[146],"most":[148,157],"often":[149,158],"for":[151,160],"research":[153,216],"Python":[155],"issues.":[162],"security":[164],"problems,":[165],"like":[166,199],"data":[167,201],"protection":[168],"model":[170],"stability,":[171],"not":[173],"looked":[174],"at":[175],"enough":[176],"present":[179,188],"research,":[180],"according":[181],"us.":[183],"study":[185],"thoroughly":[186],"also":[191],"points":[192],"out":[193],"areas":[194],"need":[196],"work,":[198],"integration":[202],"AI":[204],"systems":[205],"explained.":[209],"The":[210],"findings":[211],"should":[212],"help":[213],"guide":[214],"speed":[218],"up":[219],"creation":[221],"DL-based":[223],"identification":[225],"tools":[226],"future.":[229]},"counts_by_year":[{"year":2026,"cited_by_count":21},{"year":2025,"cited_by_count":43}],"updated_date":"2026-07-27T06:00:05.401030","created_date":"2025-10-10T00:00:00"}