{"id":"https://openalex.org/W4406530134","doi":"https://doi.org/10.1007/s10278-025-01387-9","title":"GLAC-Unet: Global-Local Active Contour Loss with an Efficient U-Shaped Architecture for Multiclass Medical Image Segmentation","display_name":"GLAC-Unet: Global-Local Active Contour Loss with an Efficient U-Shaped Architecture for Multiclass Medical Image Segmentation","publication_year":2025,"publication_date":"2025-01-17","ids":{"openalex":"https://openalex.org/W4406530134","doi":"https://doi.org/10.1007/s10278-025-01387-9","pmid":"https://pubmed.ncbi.nlm.nih.gov/39821780"},"language":"en","primary_location":{"id":"doi:10.1007/s10278-025-01387-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10278-025-01387-9","pdf_url":null,"source":{"id":"https://openalex.org/S4393920007","display_name":"Journal of Imaging Informatics in Medicine","issn_l":"2948-2925","issn":["2948-2925","2948-2933"],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Imaging Informatics in Medicine","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12572467/pdf/10278_2025_Article_1387.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061149066","display_name":"Minh-Nhat Trinh","orcid":"https://orcid.org/0000-0002-4154-5256"},"institutions":[{"id":"https://openalex.org/I71503853","display_name":"University of Algarve","ror":"https://ror.org/014g34x36","country_code":"PT","type":"education","lineage":["https://openalex.org/I71503853"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Minh-Nhat Trinh","raw_affiliation_strings":["Center of Marine Sciences, University of Algarve, Faro, Portugal"],"affiliations":[{"raw_affiliation_string":"Center of Marine Sciences, University of Algarve, Faro, Portugal","institution_ids":["https://openalex.org/I71503853"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019897482","display_name":"Thi-Thao Tran","orcid":"https://orcid.org/0009-0008-0862-1262"},"institutions":[{"id":"https://openalex.org/I94518387","display_name":"Hanoi University of Science and Technology","ror":"https://ror.org/04nyv3z04","country_code":"VN","type":"education","lineage":["https://openalex.org/I94518387"]}],"countries":["VN"],"is_corresponding":false,"raw_author_name":"Thi-Thao Tran","raw_affiliation_strings":["School of Electrical and Electronic Engineering, Hanoi University of Science and Technology, Hanoi, Vietnam"],"affiliations":[{"raw_affiliation_string":"School of Electrical and Electronic Engineering, Hanoi University of Science and Technology, Hanoi, Vietnam","institution_ids":["https://openalex.org/I94518387"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078078273","display_name":"Do-Hai-Ninh Nham","orcid":"https://orcid.org/0000-0002-8753-9062"},"institutions":[{"id":"https://openalex.org/I153267046","display_name":"University of Kaiserslautern","ror":"https://ror.org/04zrf7b53","country_code":"DE","type":"education","lineage":["https://openalex.org/I153267046"]},{"id":"https://openalex.org/I2802076133","display_name":"University of Koblenz and Landau","ror":"https://ror.org/01j9f6752","country_code":"DE","type":"education","lineage":["https://openalex.org/I2802076133"]},{"id":"https://openalex.org/I4387152675","display_name":"Rheinland-Pf\u00e4lzische Technische Universit\u00e4t Kaiserslautern-Landau","ror":"https://ror.org/01qrts582","country_code":"DE","type":"education","lineage":["https://openalex.org/I4387152675"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Do-Hai-Ninh Nham","raw_affiliation_strings":["Department of Mathematics, The University of Kaiserslautern-Landau (RPTU), Kaiserslautern, Germany"],"affiliations":[{"raw_affiliation_string":"Department of Mathematics, The University of Kaiserslautern-Landau (RPTU), Kaiserslautern, Germany","institution_ids":["https://openalex.org/I2802076133","https://openalex.org/I153267046","https://openalex.org/I4387152675"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047456186","display_name":"Men\u2010Tzung Lo","orcid":"https://orcid.org/0000-0003-2630-4945"},"institutions":[{"id":"https://openalex.org/I22265921","display_name":"National Central University","ror":"https://ror.org/00944ve71","country_code":"TW","type":"education","lineage":["https://openalex.org/I22265921"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Men-Tzung Lo","raw_affiliation_strings":["Department of Biomedical Sciences and Engineering, National Central University, Taoyuan City, Taiwan"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical Sciences and Engineering, National Central University, Taoyuan City, Taiwan","institution_ids":["https://openalex.org/I22265921"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5020470519","display_name":"Van-Truong Pham","orcid":"https://orcid.org/0000-0003-3489-0569"},"institutions":[{"id":"https://openalex.org/I94518387","display_name":"Hanoi University of Science and Technology","ror":"https://ror.org/04nyv3z04","country_code":"VN","type":"education","lineage":["https://openalex.org/I94518387"]}],"countries":["VN"],"is_corresponding":true,"raw_author_name":"Van-Truong Pham","raw_affiliation_strings":["School of Electrical and Electronic Engineering, Hanoi University of Science and Technology, Hanoi, Vietnam. truong.phamvan@hust.edu.vn","School of Electrical and Electronic Engineering, Hanoi University of Science and Technology, Hanoi, Vietnam"],"affiliations":[{"raw_affiliation_string":"School of Electrical and Electronic Engineering, Hanoi University of Science and Technology, Hanoi, Vietnam. truong.phamvan@hust.edu.vn","institution_ids":["https://openalex.org/I94518387"]},{"raw_affiliation_string":"School of Electrical and Electronic Engineering, Hanoi University of Science and Technology, Hanoi, Vietnam","institution_ids":["https://openalex.org/I94518387"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5020470519"],"corresponding_institution_ids":["https://openalex.org/I94518387"],"apc_list":null,"apc_paid":null,"fwci":4.8536,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.94204105,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":99},"biblio":{"volume":"38","issue":"5","first_page":"3198","last_page":"3220"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14510","display_name":"Medical Imaging and Analysis","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.575570285320282},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.5574547648429871},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5266596674919128},{"id":"https://openalex.org/keywords/computer-vision","display_name":"Computer vision","score":0.5067225098609924},{"id":"https://openalex.org/keywords/active-contour-model","display_name":"Active contour model","score":0.49619966745376587},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.4758198857307434},{"id":"https://openalex.org/keywords/architecture","display_name":"Architecture","score":0.46679362654685974},{"id":"https://openalex.org/keywords/image","display_name":"Image (mathematics)","score":0.44030898809432983},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.36594271659851074},{"id":"https://openalex.org/keywords/geography","display_name":"Geography","score":0.15584927797317505}],"concepts":[{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.575570285320282},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.5574547648429871},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5266596674919128},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.5067225098609924},{"id":"https://openalex.org/C112353826","wikidata":"https://www.wikidata.org/wiki/Q127313","display_name":"Active contour model","level":4,"score":0.49619966745376587},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.4758198857307434},{"id":"https://openalex.org/C123657996","wikidata":"https://www.wikidata.org/wiki/Q12271","display_name":"Architecture","level":2,"score":0.46679362654685974},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.44030898809432983},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.36594271659851074},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.15584927797317505},{"id":"https://openalex.org/C166957645","wikidata":"https://www.wikidata.org/wiki/Q23498","display_name":"Archaeology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000077321","descriptor_name":"Deep Learning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000465","descriptor_name":"Algorithms","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D007091","descriptor_name":"Image Processing, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1007/s10278-025-01387-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s10278-025-01387-9","pdf_url":null,"source":{"id":"https://openalex.org/S4393920007","display_name":"Journal of Imaging Informatics in Medicine","issn_l":"2948-2925","issn":["2948-2925","2948-2933"],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Imaging Informatics in Medicine","raw_type":"journal-article"},{"id":"pmid:39821780","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/39821780","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of imaging informatics in medicine","raw_type":null},{"id":"pmh:oai:europepmc.org:11379815","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12572467","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12572467/pdf/10278_2025_Article_1387.pdf","source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:sapientia.ualg.pt:10400.1/26768","is_oa":false,"landing_page_url":"http://hdl.handle.net/10400.1/26768","pdf_url":null,"source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"journal article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:11379815","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12572467","pdf_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC12572467/pdf/10278_2025_Article_1387.pdf","source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1842895452","display_name":null,"funder_award_id":"102.05-2021.34","funder_id":"https://openalex.org/F4320309617","funder_display_name":"National Foundation for Science and Technology Development"},{"id":"https://openalex.org/G7110693004","display_name":null,"funder_award_id":"102.05","funder_id":"https://openalex.org/F4320309617","funder_display_name":"National Foundation for Science and Technology Development"}],"funders":[{"id":"https://openalex.org/F4320309617","display_name":"National Foundation for Science and Technology Development","ror":"https://ror.org/04rw64z44"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W4406530134.pdf"},"referenced_works_count":72,"referenced_works":["https://openalex.org/W1580269359","https://openalex.org/W1677182931","https://openalex.org/W1901129140","https://openalex.org/W1921523184","https://openalex.org/W2009767800","https://openalex.org/W2072856308","https://openalex.org/W2114487471","https://openalex.org/W2116040950","https://openalex.org/W2122184585","https://openalex.org/W2132116135","https://openalex.org/W2139478903","https://openalex.org/W2188119724","https://openalex.org/W2254582863","https://openalex.org/W2559597482","https://openalex.org/W2592929672","https://openalex.org/W2734349601","https://openalex.org/W2752782242","https://openalex.org/W2793197658","https://openalex.org/W2793631099","https://openalex.org/W2794825826","https://openalex.org/W2804047627","https://openalex.org/W2884585870","https://openalex.org/W2890166761","https://openalex.org/W2903382683","https://openalex.org/W2908206262","https://openalex.org/W2920149494","https://openalex.org/W2928133111","https://openalex.org/W2932083555","https://openalex.org/W2937845726","https://openalex.org/W2953122916","https://openalex.org/W2969937244","https://openalex.org/W2970971581","https://openalex.org/W2976295171","https://openalex.org/W2997286550","https://openalex.org/W3007268491","https://openalex.org/W3014974815","https://openalex.org/W3015388942","https://openalex.org/W3038091703","https://openalex.org/W3038918411","https://openalex.org/W3081752372","https://openalex.org/W3082365061","https://openalex.org/W3102785203","https://openalex.org/W3103562302","https://openalex.org/W3112139896","https://openalex.org/W3112701542","https://openalex.org/W3127316871","https://openalex.org/W3127751679","https://openalex.org/W3130936001","https://openalex.org/W3153359550","https://openalex.org/W3160284783","https://openalex.org/W3186051098","https://openalex.org/W3186829339","https://openalex.org/W3217500219","https://openalex.org/W4206468981","https://openalex.org/W4226351492","https://openalex.org/W4312125929","https://openalex.org/W4317382439","https://openalex.org/W4319231503","https://openalex.org/W4321232185","https://openalex.org/W4361289103","https://openalex.org/W4387047512","https://openalex.org/W4388007015","https://openalex.org/W4390109369","https://openalex.org/W4391881689","https://openalex.org/W4400456009","https://openalex.org/W4403578428","https://openalex.org/W4404345267","https://openalex.org/W6618372016","https://openalex.org/W6743731764","https://openalex.org/W6746023985","https://openalex.org/W6750469568","https://openalex.org/W6789838333"],"related_works":["https://openalex.org/W2387003628","https://openalex.org/W123102278","https://openalex.org/W2081609930","https://openalex.org/W2365596436","https://openalex.org/W163453029","https://openalex.org/W2083612662","https://openalex.org/W1522196789","https://openalex.org/W2885157826","https://openalex.org/W2159463658","https://openalex.org/W4388208420"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2}],"updated_date":"2026-04-10T15:06:20.359241","created_date":"2025-10-10T00:00:00"}
