{"id":"https://openalex.org/W3172490830","doi":"https://doi.org/10.1007/s00521-021-06188-z","title":"New evaluation methods of read mapping by 17 aligners on simulated and empirical NGS data: an updated comparison of DNA- and RNA-Seq data from Illumina and Ion Torrent technologies","display_name":"New evaluation methods of read mapping by 17 aligners on simulated and empirical NGS data: an updated comparison of DNA- and RNA-Seq data from Illumina and Ion Torrent technologies","publication_year":2021,"publication_date":"2021-06-16","ids":{"openalex":"https://openalex.org/W3172490830","doi":"https://doi.org/10.1007/s00521-021-06188-z","mag":"3172490830","pmid":"https://pubmed.ncbi.nlm.nih.gov/34155424"},"language":"en","primary_location":{"id":"doi:10.1007/s00521-021-06188-z","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00521-021-06188-z","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00521-021-06188-z.pdf","source":{"id":"https://openalex.org/S147897268","display_name":"Neural Computing and Applications","issn_l":"0941-0643","issn":["0941-0643","1433-3058"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neural Computing and Applications","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://link.springer.com/content/pdf/10.1007/s00521-021-06188-z.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5031103156","display_name":"Luigi Donato","orcid":"https://orcid.org/0000-0002-5292-426X"},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]},{"id":"https://openalex.org/I53150968","display_name":"Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione","ror":"https://ror.org/04dxgvn87","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I53150968"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Luigi Donato","raw_affiliation_strings":["Department of Biomolecular Strategies, Genetics, Cutting-edge Therapies, I.E.ME.S.T., 90139 Palermo, Italy","Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125 Messina, Italy","Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125, Messina, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomolecular Strategies, Genetics, Cutting-edge Therapies, I.E.ME.S.T., 90139 Palermo, Italy","institution_ids":["https://openalex.org/I53150968"]},{"raw_affiliation_string":"Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125 Messina, Italy","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125, Messina, Italy","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038196489","display_name":"Concetta Scimone","orcid":"https://orcid.org/0000-0002-4824-1693"},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]},{"id":"https://openalex.org/I53150968","display_name":"Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione","ror":"https://ror.org/04dxgvn87","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I53150968"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Concetta Scimone","raw_affiliation_strings":["Department of Biomolecular Strategies, Genetics, Cutting-edge Therapies, I.E.ME.S.T., 90139 Palermo, Italy","Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125 Messina, Italy","Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125, Messina, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomolecular Strategies, Genetics, Cutting-edge Therapies, I.E.ME.S.T., 90139 Palermo, Italy","institution_ids":["https://openalex.org/I53150968"]},{"raw_affiliation_string":"Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125 Messina, Italy","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125, Messina, Italy","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047924014","display_name":"Carmela Rinaldi","orcid":"https://orcid.org/0000-0001-8090-1025"},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Carmela Rinaldi","raw_affiliation_strings":["Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125 Messina, Italy","Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125, Messina, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125 Messina, Italy","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125, Messina, Italy","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033624082","display_name":"Rosalia D\u2019Angelo","orcid":"https://orcid.org/0000-0001-6510-3121"},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Rosalia D\u2019Angelo","raw_affiliation_strings":["Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125, Messina, Italy"],"raw_orcid":"https://orcid.org/0000-0001-6510-3121","affiliations":[{"raw_affiliation_string":"Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125, Messina, Italy","institution_ids":["https://openalex.org/I112862951"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5069480245","display_name":"Antonina Sidoti","orcid":null},"institutions":[{"id":"https://openalex.org/I112862951","display_name":"University of Messina","ror":"https://ror.org/05ctdxz19","country_code":"IT","type":"education","lineage":["https://openalex.org/I112862951"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonina Sidoti","raw_affiliation_strings":["Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125 Messina, Italy","Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125, Messina, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125 Messina, Italy","institution_ids":["https://openalex.org/I112862951"]},{"raw_affiliation_string":"Division of Medical Biotechnologies and Preventive Medicine, Department of Biomedical and Dental Sciences and Morphofunctional Imaging, University of Messina, via C. Valeria 1, 98125, Messina, Italy","institution_ids":["https://openalex.org/I112862951"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5031103156"],"corresponding_institution_ids":["https://openalex.org/I112862951","https://openalex.org/I53150968"],"apc_list":{"value":2390,"currency":"EUR","value_usd":2990},"apc_paid":null,"fwci":1.5471,"has_fulltext":true,"cited_by_count":24,"citation_normalized_percentile":{"value":0.83016182,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"33","issue":"22","first_page":"15669","last_page":"15692"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9625999927520752,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9625999927520752,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13328","display_name":"Osteomyelitis and Bone Disorders Research","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12640","display_name":"Environmental DNA in Biodiversity Studies","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/2303","display_name":"Ecology"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7138459086418152},{"id":"https://openalex.org/keywords/dna-sequencing","display_name":"DNA sequencing","score":0.5691666603088379},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4800216257572174},{"id":"https://openalex.org/keywords/software","display_name":"Software","score":0.45309996604919434},{"id":"https://openalex.org/keywords/ion-semiconductor-sequencing","display_name":"Ion semiconductor sequencing","score":0.43378376960754395},{"id":"https://openalex.org/keywords/benchmarking","display_name":"Benchmarking","score":0.428989440202713},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1915622353553772},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.15513843297958374},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.1503126323223114}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7138459086418152},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.5691666603088379},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4800216257572174},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.45309996604919434},{"id":"https://openalex.org/C164928082","wikidata":"https://www.wikidata.org/wiki/Q6063435","display_name":"Ion semiconductor sequencing","level":4,"score":0.43378376960754395},{"id":"https://openalex.org/C86251818","wikidata":"https://www.wikidata.org/wiki/Q816754","display_name":"Benchmarking","level":2,"score":0.428989440202713},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1915622353553772},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15513843297958374},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.1503126323223114},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.0},{"id":"https://openalex.org/C162853370","wikidata":"https://www.wikidata.org/wiki/Q39809","display_name":"Marketing","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1007/s00521-021-06188-z","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00521-021-06188-z","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00521-021-06188-z.pdf","source":{"id":"https://openalex.org/S147897268","display_name":"Neural Computing and Applications","issn_l":"0941-0643","issn":["0941-0643","1433-3058"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neural Computing and Applications","raw_type":"journal-article"},{"id":"pmid:34155424","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/34155424","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neural computing & applications","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:8208613","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/8208613","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Neural Comput Appl","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/s00521-021-06188-z","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00521-021-06188-z","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00521-021-06188-z.pdf","source":{"id":"https://openalex.org/S147897268","display_name":"Neural Computing and Applications","issn_l":"0941-0643","issn":["0941-0643","1433-3058"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neural Computing and Applications","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.5299999713897705,"display_name":"Industry, innovation and infrastructure","id":"https://metadata.un.org/sdg/9"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3172490830.pdf","grobid_xml":"https://content.openalex.org/works/W3172490830.grobid-xml"},"referenced_works_count":96,"referenced_works":["https://openalex.org/W794840634","https://openalex.org/W1489607851","https://openalex.org/W1507311685","https://openalex.org/W1767867879","https://openalex.org/W1835146852","https://openalex.org/W1973530293","https://openalex.org/W1980355960","https://openalex.org/W2002875415","https://openalex.org/W2012016911","https://openalex.org/W2018604728","https://openalex.org/W2025648894","https://openalex.org/W2031550784","https://openalex.org/W2039716761","https://openalex.org/W2044364290","https://openalex.org/W2046137036","https://openalex.org/W2066419275","https://openalex.org/W2070181423","https://openalex.org/W2091193685","https://openalex.org/W2093931624","https://openalex.org/W2096173343","https://openalex.org/W2102278945","https://openalex.org/W2103441770","https://openalex.org/W2108234281","https://openalex.org/W2112113834","https://openalex.org/W2113138916","https://openalex.org/W2114031931","https://openalex.org/W2122515553","https://openalex.org/W2131088968","https://openalex.org/W2139898631","https://openalex.org/W2140729960","https://openalex.org/W2142759233","https://openalex.org/W2143110620","https://openalex.org/W2150612144","https://openalex.org/W2156715753","https://openalex.org/W2157181383","https://openalex.org/W2157539385","https://openalex.org/W2158297569","https://openalex.org/W2169456326","https://openalex.org/W2170551349","https://openalex.org/W2295828257","https://openalex.org/W2305228807","https://openalex.org/W2466826145","https://openalex.org/W2526975281","https://openalex.org/W2537565528","https://openalex.org/W2566567183","https://openalex.org/W2581264627","https://openalex.org/W2591707245","https://openalex.org/W2592216350","https://openalex.org/W2592783371","https://openalex.org/W2600407737","https://openalex.org/W2602661691","https://openalex.org/W2604585222","https://openalex.org/W2605525619","https://openalex.org/W2623802615","https://openalex.org/W2735607403","https://openalex.org/W2787742192","https://openalex.org/W2789843538","https://openalex.org/W2797956284","https://openalex.org/W2799764118","https://openalex.org/W2807818025","https://openalex.org/W2884792453","https://openalex.org/W2886757378","https://openalex.org/W2887815625","https://openalex.org/W2888193242","https://openalex.org/W2889498145","https://openalex.org/W2902947058","https://openalex.org/W2904450217","https://openalex.org/W2905473093","https://openalex.org/W2911251965","https://openalex.org/W2914267261","https://openalex.org/W2924923089","https://openalex.org/W2948769750","https://openalex.org/W2949395034","https://openalex.org/W2950464315","https://openalex.org/W2951874439","https://openalex.org/W2951951814","https://openalex.org/W2963963068","https://openalex.org/W2969831762","https://openalex.org/W2976918870","https://openalex.org/W2980426566","https://openalex.org/W3005014603","https://openalex.org/W3005642314","https://openalex.org/W3010795344","https://openalex.org/W3010964795","https://openalex.org/W3013630838","https://openalex.org/W3014151936","https://openalex.org/W3014638255","https://openalex.org/W3015800847","https://openalex.org/W3016488212","https://openalex.org/W3024549071","https://openalex.org/W3042377559","https://openalex.org/W3091035263","https://openalex.org/W3091609397","https://openalex.org/W3104237103","https://openalex.org/W3108851097","https://openalex.org/W3114491445"],"related_works":["https://openalex.org/W3009603553","https://openalex.org/W2127025027","https://openalex.org/W1848359393","https://openalex.org/W2155350564","https://openalex.org/W3031743318","https://openalex.org/W2091383172","https://openalex.org/W3011998075","https://openalex.org/W2022351219","https://openalex.org/W4236902765","https://openalex.org/W2347219288"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1}],"updated_date":"2026-04-29T09:16:38.111599","created_date":"2025-10-10T00:00:00"}