{"id":"https://openalex.org/W3131020876","doi":"https://doi.org/10.1007/s00422-021-00863-z","title":"Biological Cybernetics: 60 years and more to come","display_name":"Biological Cybernetics: 60 years and more to come","publication_year":2021,"publication_date":"2021-02-01","ids":{"openalex":"https://openalex.org/W3131020876","doi":"https://doi.org/10.1007/s00422-021-00863-z","mag":"3131020876","pmid":"https://pubmed.ncbi.nlm.nih.gov/33620520"},"language":"en","primary_location":{"id":"doi:10.1007/s00422-021-00863-z","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00422-021-00863-z","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00422-021-00863-z.pdf","source":{"id":"https://openalex.org/S87357125","display_name":"Biological Cybernetics","issn_l":"0340-1200","issn":["0340-1200","1432-0770"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Cybernetics","raw_type":"journal-article"},"type":"editorial","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s00422-021-00863-z.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005593731","display_name":"Benjamin Lindner","orcid":"https://orcid.org/0000-0001-5617-127X"},"institutions":[{"id":"https://openalex.org/I4210152641","display_name":"Bernstein Center for Computational Neuroscience Berlin","ror":"https://ror.org/05ewdps05","country_code":"DE","type":"government","lineage":["https://openalex.org/I4210092532","https://openalex.org/I4210152641"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Benjamin Lindner","raw_affiliation_strings":["Division Bernstein Center for Computational Neuroscience Berlin, Humboldt University Berlin, Philippstr. 13, Haus 2, Berlin, 10115, Germany. bc@bccn-berlin.de","Division Bernstein Center for Computational Neuroscience Berlin, Humboldt University Berlin, Philippstr. 13, Haus 2, Berlin, 10115, Germany"],"affiliations":[{"raw_affiliation_string":"Division Bernstein Center for Computational Neuroscience Berlin, Humboldt University Berlin, Philippstr. 13, Haus 2, Berlin, 10115, Germany. bc@bccn-berlin.de","institution_ids":["https://openalex.org/I4210152641"]},{"raw_affiliation_string":"Division Bernstein Center for Computational Neuroscience Berlin, Humboldt University Berlin, Philippstr. 13, Haus 2, Berlin, 10115, Germany","institution_ids":["https://openalex.org/I4210152641"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083157573","display_name":"Peter J. Thomas","orcid":"https://orcid.org/0000-0001-7533-6770"},"institutions":[{"id":"https://openalex.org/I58956616","display_name":"Case Western Reserve University","ror":"https://ror.org/051fd9666","country_code":"US","type":"education","lineage":["https://openalex.org/I58956616"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter J. Thomas","raw_affiliation_strings":["Department of Mathematics, Applied Mathematics, and Statistics, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44106, USA"],"affiliations":[{"raw_affiliation_string":"Department of Mathematics, Applied Mathematics, and Statistics, Case Western Reserve University, 10900 Euclid Avenue, Cleveland, Ohio, 44106, USA","institution_ids":["https://openalex.org/I58956616"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003609825","display_name":"Jean\u2010Marc Fellous","orcid":"https://orcid.org/0000-0003-4102-8336"},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jean-Marc Fellous","raw_affiliation_strings":["Departments of Psychology ad Biomedical Engineering, University of Arizona, 1503 E University Blvd, Tucson, AZ, 85721, USA"],"affiliations":[{"raw_affiliation_string":"Departments of Psychology ad Biomedical Engineering, University of Arizona, 1503 E University Blvd, Tucson, AZ, 85721, USA","institution_ids":["https://openalex.org/I138006243"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015482433","display_name":"Paul Tiesinga","orcid":"https://orcid.org/0000-0003-4509-6870"},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Paul Tiesinga","raw_affiliation_strings":["Donders Institute, Faculty of Science, Radboud University, Heyendaalseweg 135, Nijmegen, AJ, 6525, Netherlands"],"affiliations":[{"raw_affiliation_string":"Donders Institute, Faculty of Science, Radboud University, Heyendaalseweg 135, Nijmegen, AJ, 6525, Netherlands","institution_ids":["https://openalex.org/I145872427"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5005593731"],"corresponding_institution_ids":["https://openalex.org/I4210152641"],"apc_list":{"value":2790,"currency":"EUR","value_usd":3590},"apc_paid":{"value":2790,"currency":"EUR","value_usd":3590},"fwci":0.2434,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.51499241,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":96,"max":97},"biblio":{"volume":"115","issue":"1","first_page":"5","last_page":"6"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.6822999715805054,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.6822999715805054,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13937","display_name":"Genetics, Bioinformatics, and Biomedical Research","score":0.6198999881744385,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cybernetics","display_name":"Cybernetics","score":0.8510017395019531},{"id":"https://openalex.org/keywords/complex-system","display_name":"Complex system","score":0.6052694320678711},{"id":"https://openalex.org/keywords/biocybernetics","display_name":"Biocybernetics","score":0.5050674080848694},{"id":"https://openalex.org/keywords/cognitive-science","display_name":"Cognitive science","score":0.48161715269088745},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.392235666513443},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.3403306007385254},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.32846906781196594},{"id":"https://openalex.org/keywords/epistemology","display_name":"Epistemology","score":0.32732027769088745},{"id":"https://openalex.org/keywords/philosophy","display_name":"Philosophy","score":0.24031329154968262}],"concepts":[{"id":"https://openalex.org/C115286129","wikidata":"https://www.wikidata.org/wiki/Q123637","display_name":"Cybernetics","level":2,"score":0.8510017395019531},{"id":"https://openalex.org/C47822265","wikidata":"https://www.wikidata.org/wiki/Q854457","display_name":"Complex system","level":2,"score":0.6052694320678711},{"id":"https://openalex.org/C108426073","wikidata":"https://www.wikidata.org/wiki/Q864512","display_name":"Biocybernetics","level":3,"score":0.5050674080848694},{"id":"https://openalex.org/C188147891","wikidata":"https://www.wikidata.org/wiki/Q147638","display_name":"Cognitive science","level":1,"score":0.48161715269088745},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.392235666513443},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3403306007385254},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.32846906781196594},{"id":"https://openalex.org/C111472728","wikidata":"https://www.wikidata.org/wiki/Q9471","display_name":"Epistemology","level":1,"score":0.32732027769088745},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.24031329154968262}],"mesh":[{"descriptor_ui":"D003491","descriptor_name":"Cybernetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003491","descriptor_name":"Cybernetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D003491","descriptor_name":"Cybernetics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":5,"locations":[{"id":"doi:10.1007/s00422-021-00863-z","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00422-021-00863-z","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00422-021-00863-z.pdf","source":{"id":"https://openalex.org/S87357125","display_name":"Biological Cybernetics","issn_l":"0340-1200","issn":["0340-1200","1432-0770"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Cybernetics","raw_type":"journal-article"},{"id":"pmid:33620520","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33620520","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological cybernetics","raw_type":null},{"id":"pmh:oai:edoc.hu-berlin.de:18452/27380","is_oa":true,"landing_page_url":"http://edoc.hu-berlin.de/18452/27380","pdf_url":null,"source":{"id":"https://openalex.org/S4306400923","display_name":"edoc Publication server (Humboldt University of Berlin)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I39343248","host_organization_name":"Humboldt-Universit\u00e4t zu Berlin","host_organization_lineage":["https://openalex.org/I39343248"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"article"},{"id":"pmh:oai:frl.publisso.de:frl:6447076","is_oa":true,"landing_page_url":"https://repository.publisso.de/resource/frl:6447076","pdf_url":null,"source":{"id":"https://openalex.org/S4377196269","display_name":"PUBLISSO (German National Library of Medicine)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210112663","host_organization_name":"ZB MED - Information Centre for Life Sciences","host_organization_lineage":["https://openalex.org/I4210112663"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://lobid.org/resources/99370671255506441#!, 115(1):5-6","raw_type":"Zeitschriftenartikel"},{"id":"pmh:oai:pubmedcentral.nih.gov:7901165","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7901165","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biol Cybern","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1007/s00422-021-00863-z","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00422-021-00863-z","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00422-021-00863-z.pdf","source":{"id":"https://openalex.org/S87357125","display_name":"Biological Cybernetics","issn_l":"0340-1200","issn":["0340-1200","1432-0770"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Cybernetics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3131020876.pdf","grobid_xml":"https://content.openalex.org/works/W3131020876.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1969510989","https://openalex.org/W2353094154","https://openalex.org/W2375036654","https://openalex.org/W4231170545","https://openalex.org/W2024349756","https://openalex.org/W1507049390","https://openalex.org/W4212991614","https://openalex.org/W2029089426","https://openalex.org/W2749009009","https://openalex.org/W2072162089"],"abstract_inverted_index":{"Introduction!#!Adequate":[0],"cardiorespiratory":[1,98],"fitness":[2,99],"is":[3,37],"of":[4,24],"utmost":[5],"importance":[6],"during":[7,31,72],"spaceflight":[8],"and":[9,27,100,110,124],"should":[10],"be":[11,93,102],"assessable":[12],"via":[13],"moderate":[14],"work":[15],"rate":[16,42],"intensities,":[17],"e.g.,":[18],"using":[19],"kinetics":[20,44,90],"parameters.":[21],"The":[22],"combination":[23,119],"restricted":[25],"sleep,":[26],"defined":[28,121],"physical":[29,70,122],"exercise":[30],"a":[32,103],"45-day":[33],"simulated":[34],"space":[35],"mission":[36,74],"expected":[38],"to":[39,92,95,106,116],"slow":[40],"heart":[41],"(HR)":[43],"without":[45],"changes":[46,96],"in":[47,97,114,118],"oxygen":[48],"uptake":[49],"([Formula:":[50],"see":[51],"text])":[52],"kinetics.!##!Methods!#!Overall,":[53],"14":[54],"crew":[55],"members":[56],"(9":[57],"males,":[58],"5":[59],"females,":[60],"37":[61],"\u00b1":[62,66],"7":[63],"yrs,":[64],"23.4":[65],"3.5":[67],"kg":[68],"m!##!Results!#!CCF!##!Discussion!#!The":[69],"training":[71],"the":[73],"accelerated":[75],"HR":[76,84,89],"kinetics,":[77],"but":[78],"had":[79],"no":[80],"impact":[81],"on":[82],"mean":[83],"values":[85],"post":[86],"mission.":[87],"Thus,":[88],"seem":[91],"sensitive":[94],"may":[101],"valuable":[104],"parameter":[105],"monitor":[107],"fitness.":[108],"Kinetics":[109],"capacities":[111],"adapt":[112],"independently":[113],"response":[115],"confinement":[117],"with":[120],"activity":[123],"sleep.":[125]},"counts_by_year":[{"year":2022,"cited_by_count":3}],"updated_date":"2026-03-27T05:58:40.876381","created_date":"2025-10-10T00:00:00"}
