{"id":"https://openalex.org/W2093166308","doi":"https://doi.org/10.1007/s00422-014-0619-1","title":"Effective connectivity at synaptic level in humans: a review and future prospects","display_name":"Effective connectivity at synaptic level in humans: a review and future prospects","publication_year":2014,"publication_date":"2014-08-15","ids":{"openalex":"https://openalex.org/W2093166308","doi":"https://doi.org/10.1007/s00422-014-0619-1","mag":"2093166308","pmid":"https://pubmed.ncbi.nlm.nih.gov/25128317"},"language":"en","primary_location":{"id":"doi:10.1007/s00422-014-0619-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00422-014-0619-1","pdf_url":null,"source":{"id":"https://openalex.org/S87357125","display_name":"Biological Cybernetics","issn_l":"0340-1200","issn":["0340-1200","1432-0770"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Cybernetics","raw_type":"journal-article"},"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005213656","display_name":"\u00d6nder G\u00fcrcan","orcid":"https://orcid.org/0000-0001-6982-5658"},"institutions":[{"id":"https://openalex.org/I41641357","display_name":"Ege University","ror":"https://ror.org/02eaafc18","country_code":"TR","type":"education","lineage":["https://openalex.org/I41641357"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"\u00d6nder G\u00fcrcan","raw_affiliation_strings":["Computer Engineering Department, Ege University, Universite Cad., 35100, Bornova, Izmir, Turkey, onder.gurcan@ege.edu.tr","Computer Engineering Department, Ege University, Universite Cad., 35100, Bornova, Izmir, Turkey"],"affiliations":[{"raw_affiliation_string":"Computer Engineering Department, Ege University, Universite Cad., 35100, Bornova, Izmir, Turkey, onder.gurcan@ege.edu.tr","institution_ids":[]},{"raw_affiliation_string":"Computer Engineering Department, Ege University, Universite Cad., 35100, Bornova, Izmir, Turkey","institution_ids":["https://openalex.org/I41641357"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5005213656"],"corresponding_institution_ids":["https://openalex.org/I41641357"],"apc_list":{"value":2790,"currency":"EUR","value_usd":3590},"apc_paid":null,"fwci":0.313,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.59561809,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"108","issue":"6","first_page":"713","last_page":"733"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10241","display_name":"Functional Brain Connectivity Studies","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10502","display_name":"Advanced Memory and Neural Computing","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/2208","display_name":"Electrical and Electronic Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.5892545580863953},{"id":"https://openalex.org/keywords/complex-system","display_name":"Complex system","score":0.5357441306114197},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.497329980134964},{"id":"https://openalex.org/keywords/cognitive-science","display_name":"Cognitive science","score":0.4595126211643219},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.43290627002716064},{"id":"https://openalex.org/keywords/systems-neuroscience","display_name":"Systems neuroscience","score":0.4183329939842224},{"id":"https://openalex.org/keywords/psychology","display_name":"Psychology","score":0.3010059595108032},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2781761884689331},{"id":"https://openalex.org/keywords/central-nervous-system","display_name":"Central nervous system","score":0.1609877049922943}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.5892545580863953},{"id":"https://openalex.org/C47822265","wikidata":"https://www.wikidata.org/wiki/Q854457","display_name":"Complex system","level":2,"score":0.5357441306114197},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.497329980134964},{"id":"https://openalex.org/C188147891","wikidata":"https://www.wikidata.org/wiki/Q147638","display_name":"Cognitive science","level":1,"score":0.4595126211643219},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.43290627002716064},{"id":"https://openalex.org/C31288803","wikidata":"https://www.wikidata.org/wiki/Q2617516","display_name":"Systems neuroscience","level":5,"score":0.4183329939842224},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3010059595108032},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2781761884689331},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.1609877049922943},{"id":"https://openalex.org/C2778609137","wikidata":"https://www.wikidata.org/wiki/Q105790271","display_name":"Myelin","level":3,"score":0.0},{"id":"https://openalex.org/C2776985911","wikidata":"https://www.wikidata.org/wiki/Q916698","display_name":"Oligodendrocyte","level":4,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005544","descriptor_name":"Forecasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005544","descriptor_name":"Forecasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005544","descriptor_name":"Forecasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007395","descriptor_name":"Interneurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007395","descriptor_name":"Interneurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007395","descriptor_name":"Interneurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D007395","descriptor_name":"Interneurons","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D007395","descriptor_name":"Interneurons","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D007395","descriptor_name":"Interneurons","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D008322","descriptor_name":"Mammals","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008322","descriptor_name":"Mammals","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008322","descriptor_name":"Mammals","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D009046","descriptor_name":"Motor Neurons","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D009488","descriptor_name":"Neurosciences","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009488","descriptor_name":"Neurosciences","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009488","descriptor_name":"Neurosciences","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013045","descriptor_name":"Species Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D013116","descriptor_name":"Spinal Cord","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D013569","descriptor_name":"Synapses","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D018482","descriptor_name":"Muscle, Skeletal","qualifier_ui":"Q000294","qualifier_name":"innervation","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true},{"descriptor_ui":"D063132","descriptor_name":"Connectome","qualifier_ui":"Q000639","qualifier_name":"trends","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/s00422-014-0619-1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00422-014-0619-1","pdf_url":null,"source":{"id":"https://openalex.org/S87357125","display_name":"Biological Cybernetics","issn_l":"0340-1200","issn":["0340-1200","1432-0770"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Cybernetics","raw_type":"journal-article"},{"id":"pmid:25128317","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25128317","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological cybernetics","raw_type":null},{"id":"pmh:oai:HAL:cea-01806917v1","is_oa":false,"landing_page_url":"https://cea.hal.science/cea-01806917","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biological Cybernetics (Modeling), 2014, 108, pp.713 - 733. ⟨10.1007/s00422-014-0619-1⟩","raw_type":"Journal articles"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":146,"referenced_works":["https://openalex.org/W6093035","https://openalex.org/W9064404","https://openalex.org/W16873836","https://openalex.org/W62639009","https://openalex.org/W65738273","https://openalex.org/W172298727","https://openalex.org/W176707287","https://openalex.org/W597709495","https://openalex.org/W1481189295","https://openalex.org/W1486852018","https://openalex.org/W1508379405","https://openalex.org/W1512746852","https://openalex.org/W1514853588","https://openalex.org/W1530683550","https://openalex.org/W1552174187","https://openalex.org/W1565369861","https://openalex.org/W1569930087","https://openalex.org/W1572401739","https://openalex.org/W1590711701","https://openalex.org/W1669925514","https://openalex.org/W1750100667","https://openalex.org/W1761010261","https://openalex.org/W1847097404","https://openalex.org/W1863227302","https://openalex.org/W1867196520","https://openalex.org/W1912975988","https://openalex.org/W1965476983","https://openalex.org/W1967764809","https://openalex.org/W1969483526","https://openalex.org/W1969944285","https://openalex.org/W1974302391","https://openalex.org/W1979773754","https://openalex.org/W1979854415","https://openalex.org/W1980349290","https://openalex.org/W1983110705","https://openalex.org/W1985683154","https://openalex.org/W1985940938","https://openalex.org/W1985983039","https://openalex.org/W1986870707","https://openalex.org/W1990517441","https://openalex.org/W1995650302","https://openalex.org/W2002861841","https://openalex.org/W2003129811","https://openalex.org/W2005101215","https://openalex.org/W2006017444","https://openalex.org/W2013684097","https://openalex.org/W2014744085","https://openalex.org/W2016708835","https://openalex.org/W2018027127","https://openalex.org/W2020519533","https://openalex.org/W2020802091","https://openalex.org/W2024424774","https://openalex.org/W2026475322","https://openalex.org/W2028418738","https://openalex.org/W2028802293","https://openalex.org/W2029074321","https://openalex.org/W2039013116","https://openalex.org/W2041391841","https://openalex.org/W2042060110","https://openalex.org/W2043679829","https://openalex.org/W2044012436","https://openalex.org/W2044613381","https://openalex.org/W2044751593","https://openalex.org/W2045491133","https://openalex.org/W2046191651","https://openalex.org/W2046372172","https://openalex.org/W2046894301","https://openalex.org/W2049053063","https://openalex.org/W2053773581","https://openalex.org/W2054394248","https://openalex.org/W2058376707","https://openalex.org/W2061564920","https://openalex.org/W2061744336","https://openalex.org/W2067741599","https://openalex.org/W2068705913","https://openalex.org/W2069308336","https://openalex.org/W2078474809","https://openalex.org/W2079037974","https://openalex.org/W2081986990","https://openalex.org/W2085306742","https://openalex.org/W2087058693","https://openalex.org/W2101567517","https://openalex.org/W2103179919","https://openalex.org/W2105563853","https://openalex.org/W2111935653","https://openalex.org/W2116339921","https://openalex.org/W2117120818","https://openalex.org/W2117332865","https://openalex.org/W2117663940","https://openalex.org/W2118352903","https://openalex.org/W2118710432","https://openalex.org/W2119823590","https://openalex.org/W2120327449","https://openalex.org/W2122410182","https://openalex.org/W2124290836","https://openalex.org/W2124776405","https://openalex.org/W2125134203","https://openalex.org/W2128432504","https://openalex.org/W2131764799","https://openalex.org/W2134156766","https://openalex.org/W2138754805","https://openalex.org/W2138960099","https://openalex.org/W2139780076","https://openalex.org/W2141907517","https://openalex.org/W2142808530","https://openalex.org/W2143041522","https://openalex.org/W2148051570","https://openalex.org/W2150378486","https://openalex.org/W2152502378","https://openalex.org/W2156091557","https://openalex.org/W2163137450","https://openalex.org/W2164653071","https://openalex.org/W2166280719","https://openalex.org/W2167700167","https://openalex.org/W2168025484","https://openalex.org/W2170057251","https://openalex.org/W2170688416","https://openalex.org/W2170750178","https://openalex.org/W2171658832","https://openalex.org/W2171865010","https://openalex.org/W2180809782","https://openalex.org/W2187063188","https://openalex.org/W2207052072","https://openalex.org/W2215040991","https://openalex.org/W2327368511","https://openalex.org/W2341514930","https://openalex.org/W2406777949","https://openalex.org/W2417032001","https://openalex.org/W2490377892","https://openalex.org/W2492294785","https://openalex.org/W2498075210","https://openalex.org/W2539632242","https://openalex.org/W2582765108","https://openalex.org/W2896027395","https://openalex.org/W2911607583","https://openalex.org/W3083591227","https://openalex.org/W3133236490","https://openalex.org/W3140119090","https://openalex.org/W3140459166","https://openalex.org/W3148499377","https://openalex.org/W3148930403","https://openalex.org/W4211143448","https://openalex.org/W4234384669","https://openalex.org/W4285719527","https://openalex.org/W4292477447","https://openalex.org/W4298223230"],"related_works":["https://openalex.org/W3118263852","https://openalex.org/W2804228241","https://openalex.org/W2583788194","https://openalex.org/W4386782110","https://openalex.org/W3211517612","https://openalex.org/W4379260685","https://openalex.org/W1940423692","https://openalex.org/W2979904504","https://openalex.org/W1988997331","https://openalex.org/W2502496245"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-03-20T23:20:44.827607","created_date":"2025-10-10T00:00:00"}