{"id":"https://openalex.org/W1998041052","doi":"https://doi.org/10.1007/s00422-007-0196-7","title":"Computational modeling of paroxysmal depolarization shifts in neurons induced by the glutamate release from astrocytes","display_name":"Computational modeling of paroxysmal depolarization shifts in neurons induced by the glutamate release from astrocytes","publication_year":2007,"publication_date":"2007-12-06","ids":{"openalex":"https://openalex.org/W1998041052","doi":"https://doi.org/10.1007/s00422-007-0196-7","mag":"1998041052","pmid":"https://pubmed.ncbi.nlm.nih.gov/18064484"},"language":"en","primary_location":{"id":"doi:10.1007/s00422-007-0196-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00422-007-0196-7","pdf_url":null,"source":{"id":"https://openalex.org/S87357125","display_name":"Biological Cybernetics","issn_l":"0340-1200","issn":["0340-1200","1432-0770"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Cybernetics","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5070127159","display_name":"Alexander Silchenko","orcid":"https://orcid.org/0000-0001-5591-238X"},"institutions":[{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Alexander N. Silchenko","raw_affiliation_strings":["Institute of Neuroscience and Biophysics 3 - Medicine, Research Center Juelich, 52425, Juelich, Germany. a.silchenko@fz-juelich.de","Institute of Neuroscience and Biophysics 3 - Medicine, Research Center Juelich, 52425, Juelich, Germany"],"affiliations":[{"raw_affiliation_string":"Institute of Neuroscience and Biophysics 3 - Medicine, Research Center Juelich, 52425, Juelich, Germany. a.silchenko@fz-juelich.de","institution_ids":["https://openalex.org/I171892758"]},{"raw_affiliation_string":"Institute of Neuroscience and Biophysics 3 - Medicine, Research Center Juelich, 52425, Juelich, Germany","institution_ids":["https://openalex.org/I171892758"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5078406508","display_name":"Peter A. Tass","orcid":"https://orcid.org/0000-0002-5736-7415"},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]},{"id":"https://openalex.org/I4210140243","display_name":"Samueli Institute","ror":"https://ror.org/03teef091","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210140243"]},{"id":"https://openalex.org/I171892758","display_name":"Forschungszentrum J\u00fclich","ror":"https://ror.org/02nv7yv05","country_code":"DE","type":"facility","lineage":["https://openalex.org/I1305996414","https://openalex.org/I171892758"]},{"id":"https://openalex.org/I4210166946","display_name":"Imaging Center","ror":"https://ror.org/05hsqsk33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210166946"]}],"countries":["DE","US"],"is_corresponding":false,"raw_author_name":"Peter A. Tass","raw_affiliation_strings":["Brain Imaging Center West, Leo-Brandt-Street, 52425, Juelich, Germany","Institute of Neuromodulation, University of Cologne, 50924, Cologne, Germany","Institute of Neuroscience and Biophysics 3 - Medicine, Research Center Juelich, 52425, Juelich, Germany","Virtual Institute of Neuromodulation, Research Center Juelich, 52425, Juelich, Germany"],"affiliations":[{"raw_affiliation_string":"Brain Imaging Center West, Leo-Brandt-Street, 52425, Juelich, Germany","institution_ids":["https://openalex.org/I4210166946"]},{"raw_affiliation_string":"Institute of Neuromodulation, University of Cologne, 50924, Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]},{"raw_affiliation_string":"Institute of Neuroscience and Biophysics 3 - Medicine, Research Center Juelich, 52425, Juelich, Germany","institution_ids":["https://openalex.org/I171892758"]},{"raw_affiliation_string":"Virtual Institute of Neuromodulation, Research Center Juelich, 52425, Juelich, Germany","institution_ids":["https://openalex.org/I4210140243"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5070127159"],"corresponding_institution_ids":["https://openalex.org/I171892758"],"apc_list":{"value":2790,"currency":"EUR","value_usd":3590},"apc_paid":null,"fwci":1.5145,"has_fulltext":false,"cited_by_count":60,"citation_normalized_percentile":{"value":0.79030039,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"98","issue":"1","first_page":"61","last_page":"74"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12236","display_name":"Photoreceptor and optogenetics research","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10581","display_name":"Neural dynamics and brain function","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glutamate-receptor","display_name":"Glutamate receptor","score":0.837998628616333},{"id":"https://openalex.org/keywords/astrocyte","display_name":"Astrocyte","score":0.7752856016159058},{"id":"https://openalex.org/keywords/depolarization","display_name":"Depolarization","score":0.7556723952293396},{"id":"https://openalex.org/keywords/neuroscience","display_name":"Neuroscience","score":0.6967683434486389},{"id":"https://openalex.org/keywords/biophysics","display_name":"Biophysics","score":0.5265206098556519},{"id":"https://openalex.org/keywords/exocytosis","display_name":"Exocytosis","score":0.5250817537307739},{"id":"https://openalex.org/keywords/premovement-neuronal-activity","display_name":"Premovement neuronal activity","score":0.44564592838287354},{"id":"https://openalex.org/keywords/metabotropic-glutamate-receptor","display_name":"Metabotropic glutamate receptor","score":0.419874906539917},{"id":"https://openalex.org/keywords/calcium-in-biology","display_name":"Calcium in biology","score":0.41591233015060425},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.414612740278244},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3969348967075348},{"id":"https://openalex.org/keywords/intracellular","display_name":"Intracellular","score":0.39187198877334595},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.27630841732025146},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.25129514932632446},{"id":"https://openalex.org/keywords/central-nervous-system","display_name":"Central nervous system","score":0.21784764528274536},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.12130483984947205}],"concepts":[{"id":"https://openalex.org/C61174792","wikidata":"https://www.wikidata.org/wiki/Q420510","display_name":"Glutamate receptor","level":3,"score":0.837998628616333},{"id":"https://openalex.org/C2777542381","wikidata":"https://www.wikidata.org/wiki/Q502961","display_name":"Astrocyte","level":3,"score":0.7752856016159058},{"id":"https://openalex.org/C4141045","wikidata":"https://www.wikidata.org/wiki/Q83183","display_name":"Depolarization","level":2,"score":0.7556723952293396},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6967683434486389},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.5265206098556519},{"id":"https://openalex.org/C175969161","wikidata":"https://www.wikidata.org/wiki/Q323426","display_name":"Exocytosis","level":3,"score":0.5250817537307739},{"id":"https://openalex.org/C74254510","wikidata":"https://www.wikidata.org/wiki/Q7240508","display_name":"Premovement neuronal activity","level":2,"score":0.44564592838287354},{"id":"https://openalex.org/C49051014","wikidata":"https://www.wikidata.org/wiki/Q2033959","display_name":"Metabotropic glutamate receptor","level":4,"score":0.419874906539917},{"id":"https://openalex.org/C181080969","wikidata":"https://www.wikidata.org/wiki/Q60097","display_name":"Calcium in biology","level":3,"score":0.41591233015060425},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.414612740278244},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3969348967075348},{"id":"https://openalex.org/C79879829","wikidata":"https://www.wikidata.org/wiki/Q5571762","display_name":"Intracellular","level":2,"score":0.39187198877334595},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.27630841732025146},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.25129514932632446},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.21784764528274536},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12130483984947205},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D001253","descriptor_name":"Astrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001253","descriptor_name":"Astrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001253","descriptor_name":"Astrocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008959","descriptor_name":"Models, Neurological","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018698","descriptor_name":"Glutamic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018698","descriptor_name":"Glutamic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018698","descriptor_name":"Glutamic Acid","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D019295","descriptor_name":"Computational Biology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s00422-007-0196-7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s00422-007-0196-7","pdf_url":null,"source":{"id":"https://openalex.org/S87357125","display_name":"Biological Cybernetics","issn_l":"0340-1200","issn":["0340-1200","1432-0770"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological Cybernetics","raw_type":"journal-article"},{"id":"pmid:18064484","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18064484","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biological cybernetics","raw_type":null},{"id":"pmh:oai:juser.fz-juelich.de:14770","is_oa":false,"landing_page_url":"http://juser.fz-juelich.de/record/14770","pdf_url":null,"source":{"id":"https://openalex.org/S4306401090","display_name":"JuSER (Forschungszentrum J\u00fclich)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I171892758","host_organization_name":"Forschungszentrum J\u00fclich","host_organization_lineage":["https://openalex.org/I171892758"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biological cybernetics 98, 61 - 74 (2008). doi:10.1007/s00422-007-0196-7","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":73,"referenced_works":["https://openalex.org/W1486208308","https://openalex.org/W1500581425","https://openalex.org/W1535641516","https://openalex.org/W1586815960","https://openalex.org/W1590117132","https://openalex.org/W1600549717","https://openalex.org/W1642181682","https://openalex.org/W1897919376","https://openalex.org/W1943910815","https://openalex.org/W1965893090","https://openalex.org/W1966907942","https://openalex.org/W1967192722","https://openalex.org/W1971016259","https://openalex.org/W1974807815","https://openalex.org/W1978836458","https://openalex.org/W1980618916","https://openalex.org/W1982558709","https://openalex.org/W1982950909","https://openalex.org/W1986246844","https://openalex.org/W1990220309","https://openalex.org/W1999208340","https://openalex.org/W2002789216","https://openalex.org/W2015949591","https://openalex.org/W2016719895","https://openalex.org/W2017523469","https://openalex.org/W2024292538","https://openalex.org/W2026154459","https://openalex.org/W2032730787","https://openalex.org/W2033797809","https://openalex.org/W2034565593","https://openalex.org/W2034899304","https://openalex.org/W2036838450","https://openalex.org/W2044232368","https://openalex.org/W2044730840","https://openalex.org/W2045762344","https://openalex.org/W2050452462","https://openalex.org/W2053739364","https://openalex.org/W2055244899","https://openalex.org/W2060689618","https://openalex.org/W2061642869","https://openalex.org/W2070948004","https://openalex.org/W2073263421","https://openalex.org/W2074042825","https://openalex.org/W2076082077","https://openalex.org/W2077274654","https://openalex.org/W2083744508","https://openalex.org/W2084722225","https://openalex.org/W2088299086","https://openalex.org/W2088988616","https://openalex.org/W2090971379","https://openalex.org/W2095923239","https://openalex.org/W2104417933","https://openalex.org/W2108809409","https://openalex.org/W2109078104","https://openalex.org/W2111547035","https://openalex.org/W2117530806","https://openalex.org/W2120613443","https://openalex.org/W2123519003","https://openalex.org/W2123609069","https://openalex.org/W2133315293","https://openalex.org/W2134230622","https://openalex.org/W2135328571","https://openalex.org/W2139411310","https://openalex.org/W2147101007","https://openalex.org/W2154100802","https://openalex.org/W2154759314","https://openalex.org/W2156094132","https://openalex.org/W2164938885","https://openalex.org/W2185212694","https://openalex.org/W2411086663","https://openalex.org/W2496982173","https://openalex.org/W4210979710","https://openalex.org/W4234546939"],"related_works":["https://openalex.org/W2131792212","https://openalex.org/W4366235780","https://openalex.org/W2283539280","https://openalex.org/W2951899425","https://openalex.org/W2137197598","https://openalex.org/W4225147667","https://openalex.org/W3182878900","https://openalex.org/W3002370256","https://openalex.org/W4319299256","https://openalex.org/W2975749752"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":6}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}