{"id":"https://openalex.org/W3199344981","doi":"https://doi.org/10.1007/s00180-021-01148-6","title":"Hierarchical correction of p-values via an ultrametric tree running Ornstein-Uhlenbeck process","display_name":"Hierarchical correction of p-values via an ultrametric tree running Ornstein-Uhlenbeck process","publication_year":2021,"publication_date":"2021-09-12","ids":{"openalex":"https://openalex.org/W3199344981","doi":"https://doi.org/10.1007/s00180-021-01148-6","mag":"3199344981"},"language":"en","primary_location":{"id":"doi:10.1007/s00180-021-01148-6","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00180-021-01148-6","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00180-021-01148-6.pdf","source":{"id":"https://openalex.org/S8500805","display_name":"Computational Statistics","issn_l":"0943-4062","issn":["0943-4062","1613-9658"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational Statistics","raw_type":"journal-article"},"type":"article","indexed_in":["arxiv","crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/s00180-021-01148-6.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057437870","display_name":"Antoine Bichat","orcid":"https://orcid.org/0000-0001-6599-7081"},"institutions":[{"id":"https://openalex.org/I4210102442","display_name":"Enterome (France)","ror":"https://ror.org/0139s2465","country_code":"FR","type":"company","lineage":["https://openalex.org/I4210102442"]},{"id":"https://openalex.org/I4210155549","display_name":"Laboratoire de Math\u00e9matiques Blaise Pascal","ror":"https://ror.org/05sd5r855","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I198244214","https://openalex.org/I4210141950","https://openalex.org/I4210155549"]},{"id":"https://openalex.org/I4387153769","display_name":"Laboratoire de Math\u00e9matiques et Mod\u00e9lisation d'\u00c9vry","ror":"https://ror.org/03jca6281","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I277688954","https://openalex.org/I4210097372","https://openalex.org/I4387153769","https://openalex.org/I88467170"]},{"id":"https://openalex.org/I88467170","display_name":"Universit\u00e9 d'\u00c9vry Val-d'Essonne","ror":"https://ror.org/00e96v939","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954","https://openalex.org/I88467170"]}],"countries":["FR"],"is_corresponding":true,"raw_author_name":"Antoine Bichat","raw_affiliation_strings":["Enterome, 94-96 Avenue Ledru Rollin, 75011, Paris, France","LaMME, Universit\u00e9 d\u2019\u00c9vry val d\u2019Essonne, 91000, \u00c9vry, France","Enterome (France)","LaMME - Laboratoire de Math\u00e9matiques et Mod\u00e9lisation d'Evry (IBGBI, 23 boulevard de France\r\n91037 Evry - France)"],"raw_orcid":"https://orcid.org/0000-0001-6599-7081","affiliations":[{"raw_affiliation_string":"Enterome, 94-96 Avenue Ledru Rollin, 75011, Paris, France","institution_ids":["https://openalex.org/I4210102442"]},{"raw_affiliation_string":"LaMME, Universit\u00e9 d\u2019\u00c9vry val d\u2019Essonne, 91000, \u00c9vry, France","institution_ids":["https://openalex.org/I88467170"]},{"raw_affiliation_string":"Enterome (France)","institution_ids":["https://openalex.org/I4210102442"]},{"raw_affiliation_string":"LaMME - Laboratoire de Math\u00e9matiques et Mod\u00e9lisation d'Evry (IBGBI, 23 boulevard de France\r\n91037 Evry - France)","institution_ids":["https://openalex.org/I4210155549","https://openalex.org/I4387153769"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089457658","display_name":"Christophe Ambroise","orcid":"https://orcid.org/0000-0002-8148-0346"},"institutions":[{"id":"https://openalex.org/I4210155549","display_name":"Laboratoire de Math\u00e9matiques Blaise Pascal","ror":"https://ror.org/05sd5r855","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I198244214","https://openalex.org/I4210141950","https://openalex.org/I4210155549"]},{"id":"https://openalex.org/I4387153769","display_name":"Laboratoire de Math\u00e9matiques et Mod\u00e9lisation d'\u00c9vry","ror":"https://ror.org/03jca6281","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I277688954","https://openalex.org/I4210097372","https://openalex.org/I4387153769","https://openalex.org/I88467170"]},{"id":"https://openalex.org/I88467170","display_name":"Universit\u00e9 d'\u00c9vry Val-d'Essonne","ror":"https://ror.org/00e96v939","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954","https://openalex.org/I88467170"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Christophe Ambroise","raw_affiliation_strings":["LaMME, Universit\u00e9 d\u2019\u00c9vry val d\u2019Essonne, 91000, \u00c9vry, France","LaMME - Laboratoire de Math\u00e9matiques et Mod\u00e9lisation d'Evry (IBGBI, 23 boulevard de France\r\n91037 Evry - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"LaMME, Universit\u00e9 d\u2019\u00c9vry val d\u2019Essonne, 91000, \u00c9vry, France","institution_ids":["https://openalex.org/I88467170"]},{"raw_affiliation_string":"LaMME - Laboratoire de Math\u00e9matiques et Mod\u00e9lisation d'Evry (IBGBI, 23 boulevard de France\r\n91037 Evry - France)","institution_ids":["https://openalex.org/I4210155549","https://openalex.org/I4387153769"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5055648418","display_name":"Mahendra Mariadassou","orcid":"https://orcid.org/0000-0003-2986-354X"},"institutions":[{"id":"https://openalex.org/I277688954","display_name":"Universit\u00e9 Paris-Saclay","ror":"https://ror.org/03xjwb503","country_code":"FR","type":"education","lineage":["https://openalex.org/I277688954"]},{"id":"https://openalex.org/I4210088668","display_name":"Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement","ror":"https://ror.org/003vg9w96","country_code":"FR","type":"government","lineage":["https://openalex.org/I4210088668"]},{"id":"https://openalex.org/I4210159481","display_name":"Math\u00e9matiques et Informatique Appliqu\u00e9es du G\u00e9nome \u00e0 l'Environnement","ror":"https://ror.org/05qdnns64","country_code":"FR","type":"facility","lineage":["https://openalex.org/I4210088668","https://openalex.org/I4210159481"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Mahendra Mariadassou","raw_affiliation_strings":["MaIAGE, INRAE, Universit\u00e9 Paris-Saclay, 78350, Jouy-en-Josas, France","MaIAGE - Math\u00e9matiques et Informatique Appliqu\u00e9es du G\u00e9nome \u00e0 l'Environnement [Jouy-En-Josas] (B\u00e2t. 233, Domaine de Vilvert - 78352 Jouy-en-Josas Cedex - France)"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"MaIAGE, INRAE, Universit\u00e9 Paris-Saclay, 78350, Jouy-en-Josas, France","institution_ids":["https://openalex.org/I4210159481","https://openalex.org/I277688954","https://openalex.org/I4210088668"]},{"raw_affiliation_string":"MaIAGE - Math\u00e9matiques et Informatique Appliqu\u00e9es du G\u00e9nome \u00e0 l'Environnement [Jouy-En-Josas] (B\u00e2t. 233, Domaine de Vilvert - 78352 Jouy-en-Josas Cedex - France)","institution_ids":["https://openalex.org/I4210159481"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5057437870"],"corresponding_institution_ids":["https://openalex.org/I4210102442","https://openalex.org/I4210155549","https://openalex.org/I4387153769","https://openalex.org/I88467170"],"apc_list":{"value":2490,"currency":"EUR","value_usd":3090},"apc_paid":{"value":2190,"currency":"EUR","value_usd":2361},"fwci":1.3655,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.79269622,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"37","issue":"3","first_page":"995","last_page":"1013"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13234","display_name":"advanced mathematical theories","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/2610","display_name":"Mathematical Physics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T13234","display_name":"advanced mathematical theories","score":0.9959999918937683,"subfield":{"id":"https://openalex.org/subfields/2610","display_name":"Mathematical Physics"},"field":{"id":"https://openalex.org/fields/26","display_name":"Mathematics"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10067","display_name":"Stochastic processes and financial applications","score":0.9936000108718872,"subfield":{"id":"https://openalex.org/subfields/2003","display_name":"Finance"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10282","display_name":"Financial Risk and Volatility Modeling","score":0.9627000093460083,"subfield":{"id":"https://openalex.org/subfields/2003","display_name":"Finance"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ultrametric-space","display_name":"Ultrametric space","score":0.9484191536903381},{"id":"https://openalex.org/keywords/ornstein\u2013uhlenbeck-process","display_name":"Ornstein\u2013Uhlenbeck process","score":0.8458479642868042},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.5874592065811157},{"id":"https://openalex.org/keywords/tree","display_name":"Tree (set theory)","score":0.5157887935638428},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.4332549273967743},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.362338125705719},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.32017040252685547},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.30479252338409424},{"id":"https://openalex.org/keywords/discrete-mathematics","display_name":"Discrete mathematics","score":0.2363351285457611},{"id":"https://openalex.org/keywords/stochastic-process","display_name":"Stochastic process","score":0.17683064937591553}],"concepts":[{"id":"https://openalex.org/C61067352","wikidata":"https://www.wikidata.org/wiki/Q1897429","display_name":"Ultrametric space","level":3,"score":0.9484191536903381},{"id":"https://openalex.org/C31634936","wikidata":"https://www.wikidata.org/wiki/Q1757587","display_name":"Ornstein\u2013Uhlenbeck process","level":3,"score":0.8458479642868042},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.5874592065811157},{"id":"https://openalex.org/C113174947","wikidata":"https://www.wikidata.org/wiki/Q2859736","display_name":"Tree (set theory)","level":2,"score":0.5157887935638428},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.4332549273967743},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.362338125705719},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.32017040252685547},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.30479252338409424},{"id":"https://openalex.org/C118615104","wikidata":"https://www.wikidata.org/wiki/Q121416","display_name":"Discrete mathematics","level":1,"score":0.2363351285457611},{"id":"https://openalex.org/C8272713","wikidata":"https://www.wikidata.org/wiki/Q176737","display_name":"Stochastic process","level":2,"score":0.17683064937591553},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0},{"id":"https://openalex.org/C198043062","wikidata":"https://www.wikidata.org/wiki/Q180953","display_name":"Metric space","level":2,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1007/s00180-021-01148-6","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00180-021-01148-6","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00180-021-01148-6.pdf","source":{"id":"https://openalex.org/S8500805","display_name":"Computational Statistics","issn_l":"0943-4062","issn":["0943-4062","1613-9658"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational Statistics","raw_type":"journal-article"},{"id":"pmh:oai:arXiv.org:2009.13335","is_oa":true,"landing_page_url":"http://arxiv.org/abs/2009.13335","pdf_url":"https://arxiv.org/pdf/2009.13335","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"text"},{"id":"pmh:oai:HAL:hal-04072108v1","is_oa":true,"landing_page_url":"https://hal.inrae.fr/hal-04072108","pdf_url":null,"source":{"id":"https://openalex.org/S4306402512","display_name":"HAL (Le Centre pour la Communication Scientifique Directe)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1294671590","host_organization_name":"Centre National de la Recherche Scientifique","host_organization_lineage":["https://openalex.org/I1294671590"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Computational Statistics, 2022, 37 (3), pp.995-1013. &#x27E8;10.1007/s00180-021-01148-6&#x27E9;","raw_type":"Journal articles"},{"id":"pmh:oai:RePEc:spr:compst:v:37:y:2022:i:3:d:10.1007_s00180-021-01148-6","is_oa":false,"landing_page_url":"http://link.springer.com/10.1007/s00180-021-01148-6","pdf_url":null,"source":{"id":"https://openalex.org/S4306401271","display_name":"RePEc: Research Papers in Economics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I77793887","host_organization_name":"Federal Reserve Bank of St. Louis","host_organization_lineage":["https://openalex.org/I77793887"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"doi:10.1007/s00180-021-01148-6","is_oa":true,"landing_page_url":"https://doi.org/10.1007/s00180-021-01148-6","pdf_url":"https://link.springer.com/content/pdf/10.1007/s00180-021-01148-6.pdf","source":{"id":"https://openalex.org/S8500805","display_name":"Computational Statistics","issn_l":"0943-4062","issn":["0943-4062","1613-9658"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational Statistics","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W3199344981.pdf","grobid_xml":"https://content.openalex.org/works/W3199344981.grobid-xml"},"referenced_works_count":68,"referenced_works":["https://openalex.org/W1528177290","https://openalex.org/W1579271636","https://openalex.org/W1596515083","https://openalex.org/W1635102558","https://openalex.org/W1857789879","https://openalex.org/W1869362176","https://openalex.org/W1966206981","https://openalex.org/W1968950612","https://openalex.org/W1972978214","https://openalex.org/W1974530346","https://openalex.org/W1981684917","https://openalex.org/W1986136207","https://openalex.org/W1986589809","https://openalex.org/W1993131575","https://openalex.org/W2001842053","https://openalex.org/W2025956781","https://openalex.org/W2026906073","https://openalex.org/W2032279931","https://openalex.org/W2037320822","https://openalex.org/W2041693368","https://openalex.org/W2047795990","https://openalex.org/W2069119359","https://openalex.org/W2102760656","https://openalex.org/W2104093114","https://openalex.org/W2104432572","https://openalex.org/W2108562800","https://openalex.org/W2110065044","https://openalex.org/W2128235479","https://openalex.org/W2133856765","https://openalex.org/W2135046866","https://openalex.org/W2147606185","https://openalex.org/W2150092391","https://openalex.org/W2154972590","https://openalex.org/W2157795344","https://openalex.org/W2170435768","https://openalex.org/W2229664587","https://openalex.org/W2269465602","https://openalex.org/W2464096417","https://openalex.org/W2488678869","https://openalex.org/W2510675082","https://openalex.org/W2562805374","https://openalex.org/W2583479953","https://openalex.org/W2612324143","https://openalex.org/W2768727455","https://openalex.org/W2798084948","https://openalex.org/W2802105404","https://openalex.org/W2947440980","https://openalex.org/W2952200190","https://openalex.org/W2963502225","https://openalex.org/W2987747596","https://openalex.org/W2998840182","https://openalex.org/W3010193979","https://openalex.org/W3017216193","https://openalex.org/W3040750741","https://openalex.org/W3100780377","https://openalex.org/W3101280595","https://openalex.org/W3101939697","https://openalex.org/W3103324688","https://openalex.org/W3118862598","https://openalex.org/W3129844785","https://openalex.org/W3135415606","https://openalex.org/W3160500979","https://openalex.org/W4252684946","https://openalex.org/W4287760825","https://openalex.org/W4294107304","https://openalex.org/W4327812366","https://openalex.org/W4362223627","https://openalex.org/W4399612323"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W4395449128","https://openalex.org/W4287598215","https://openalex.org/W3105794585","https://openalex.org/W4236333616","https://openalex.org/W2999666600","https://openalex.org/W2054856023","https://openalex.org/W4245978557","https://openalex.org/W4285726363","https://openalex.org/W1612061217"],"abstract_inverted_index":{"Abstract":[0],"Statistical":[1],"testing":[2,28],"is":[3,49,87,97],"classically":[4],"used":[5,50],"as":[6],"an":[7,39],"exploratory":[8],"tool":[9],"to":[10,26,83],"search":[11],"for":[12,51,68],"association":[13],"between":[14,36],"a":[15,33,43,58,90],"phenotype":[16],"and":[17],"many":[18],"possible":[19],"explanatory":[20],"variables.":[21],"This":[22],"approach":[23],"often":[24],"leads":[25],"multiple":[27],"under":[29],"dependence.":[30],"We":[31,56],"assume":[32],"hierarchical":[34],"structure":[35,48],"tests":[37],"via":[38,79],"Ornstein-Uhlenbeck":[40,66],"process":[41,46,67],"on":[42,89],"tree.":[44],"The":[45,72,93],"correlation":[47],"smoothing":[52],"the":[53,62,65,75],"p":[54,69],"-values.":[55],"design":[57],"penalized":[59],"estimation":[60],"of":[61,64,74],"mean":[63],"-value":[70],"computation.":[71],"performances":[73],"algorithm":[76],"are":[77],"assessed":[78],"simulations.":[80],"Its":[81],"ability":[82],"discover":[84],"new":[85],"associations":[86],"demonstrated":[88],"metagenomic":[91],"dataset.":[92],"corresponding":[94],"R":[95],"package":[96],"available":[98],"from":[99],"https://github.com/abichat/zazou":[100],".":[101]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1}],"updated_date":"2026-05-07T13:39:58.223016","created_date":"2025-10-10T00:00:00"}
