{"id":"https://openalex.org/W4385376554","doi":"https://doi.org/10.1007/978-981-99-4749-2_65","title":"An Efficient Drug Design Method Based on Drug-Target Affinity","display_name":"An Efficient Drug Design Method Based on Drug-Target Affinity","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W4385376554","doi":"https://doi.org/10.1007/978-981-99-4749-2_65"},"language":"en","primary_location":{"id":"doi:10.1007/978-981-99-4749-2_65","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-981-99-4749-2_65","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100449218","display_name":"Haoran Liu","orcid":"https://orcid.org/0000-0001-6829-2650"},"institutions":[{"id":"https://openalex.org/I43922553","display_name":"Wuhan University of Science and Technology","ror":"https://ror.org/00e4hrk88","country_code":"CN","type":"education","lineage":["https://openalex.org/I43922553"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Haoran Liu","raw_affiliation_strings":["School of Computer Science and Technology, Wuhan University of Science and Technology, Wuhan, China","The Hubei Key Laboratory of Intelligent Information Processing and Real-Time Industrial System, Wuhan University of Science and Technology, Wuhan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Wuhan University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I43922553"]},{"raw_affiliation_string":"The Hubei Key Laboratory of Intelligent Information Processing and Real-Time Industrial System, Wuhan University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I43922553"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100395673","display_name":"Xiaolong Zhang","orcid":"https://orcid.org/0000-0001-5615-2044"},"institutions":[{"id":"https://openalex.org/I43922553","display_name":"Wuhan University of Science and Technology","ror":"https://ror.org/00e4hrk88","country_code":"CN","type":"education","lineage":["https://openalex.org/I43922553"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Xiaolong Zhang","raw_affiliation_strings":["School of Computer Science and Technology, Wuhan University of Science and Technology, Wuhan, China","The Hubei Key Laboratory of Intelligent Information Processing and Real-Time Industrial System, Wuhan University of Science and Technology, Wuhan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Wuhan University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I43922553"]},{"raw_affiliation_string":"The Hubei Key Laboratory of Intelligent Information Processing and Real-Time Industrial System, Wuhan University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I43922553"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064053470","display_name":"Xiaoli Lin","orcid":null},"institutions":[{"id":"https://openalex.org/I43922553","display_name":"Wuhan University of Science and Technology","ror":"https://ror.org/00e4hrk88","country_code":"CN","type":"education","lineage":["https://openalex.org/I43922553"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaoli Lin","raw_affiliation_strings":["School of Computer Science and Technology, Wuhan University of Science and Technology, Wuhan, China","The Hubei Key Laboratory of Intelligent Information Processing and Real-Time Industrial System, Wuhan University of Science and Technology, Wuhan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Wuhan University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I43922553"]},{"raw_affiliation_string":"The Hubei Key Laboratory of Intelligent Information Processing and Real-Time Industrial System, Wuhan University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I43922553"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101421877","display_name":"Jing Hu","orcid":"https://orcid.org/0000-0003-1348-8773"},"institutions":[{"id":"https://openalex.org/I43922553","display_name":"Wuhan University of Science and Technology","ror":"https://ror.org/00e4hrk88","country_code":"CN","type":"education","lineage":["https://openalex.org/I43922553"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Hu","raw_affiliation_strings":["School of Computer Science and Technology, Wuhan University of Science and Technology, Wuhan, China","The Hubei Key Laboratory of Intelligent Information Processing and Real-Time Industrial System, Wuhan University of Science and Technology, Wuhan, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer Science and Technology, Wuhan University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I43922553"]},{"raw_affiliation_string":"The Hubei Key Laboratory of Intelligent Information Processing and Real-Time Industrial System, Wuhan University of Science and Technology, Wuhan, China","institution_ids":["https://openalex.org/I43922553"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5100395673"],"corresponding_institution_ids":["https://openalex.org/I43922553"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"764","last_page":"775"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9830999970436096,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10274","display_name":"Synthesis and biological activity","score":0.9821000099182129,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.7755289673805237},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7086016535758972},{"id":"https://openalex.org/keywords/drug-design","display_name":"Drug design","score":0.5623015761375427},{"id":"https://openalex.org/keywords/drug-target","display_name":"Drug target","score":0.5112814903259277},{"id":"https://openalex.org/keywords/coding","display_name":"Coding (social sciences)","score":0.4513040781021118},{"id":"https://openalex.org/keywords/drug-development","display_name":"Drug development","score":0.4353407025337219},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.428910493850708},{"id":"https://openalex.org/keywords/docking","display_name":"Docking (animal)","score":0.41253432631492615},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3558175265789032},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.32834580540657043},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.21251040697097778},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.1565905511379242},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.10019457340240479},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.08679842948913574},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.07792726159095764},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.07364308834075928}],"concepts":[{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.7755289673805237},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7086016535758972},{"id":"https://openalex.org/C192071366","wikidata":"https://www.wikidata.org/wiki/Q2991682","display_name":"Drug design","level":2,"score":0.5623015761375427},{"id":"https://openalex.org/C2989108626","wikidata":"https://www.wikidata.org/wiki/Q904407","display_name":"Drug target","level":2,"score":0.5112814903259277},{"id":"https://openalex.org/C179518139","wikidata":"https://www.wikidata.org/wiki/Q5140297","display_name":"Coding (social sciences)","level":2,"score":0.4513040781021118},{"id":"https://openalex.org/C64903051","wikidata":"https://www.wikidata.org/wiki/Q2198549","display_name":"Drug development","level":3,"score":0.4353407025337219},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.428910493850708},{"id":"https://openalex.org/C41685203","wikidata":"https://www.wikidata.org/wiki/Q1974042","display_name":"Docking (animal)","level":2,"score":0.41253432631492615},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3558175265789032},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.32834580540657043},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.21251040697097778},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.1565905511379242},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10019457340240479},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.08679842948913574},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.07792726159095764},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.07364308834075928},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.0},{"id":"https://openalex.org/C159110408","wikidata":"https://www.wikidata.org/wiki/Q121176","display_name":"Nursing","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-981-99-4749-2_65","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-981-99-4749-2_65","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W1975147762","https://openalex.org/W1981622697","https://openalex.org/W2028279608","https://openalex.org/W2031390939","https://openalex.org/W2041686943","https://openalex.org/W2064675550","https://openalex.org/W2105668062","https://openalex.org/W2134967712","https://openalex.org/W2604527271","https://openalex.org/W2784055414","https://openalex.org/W2900090807","https://openalex.org/W2901411193","https://openalex.org/W2919115771","https://openalex.org/W2966111606","https://openalex.org/W2970971581","https://openalex.org/W3003217347","https://openalex.org/W3011701533","https://openalex.org/W3013657235","https://openalex.org/W3015608194","https://openalex.org/W3023594261","https://openalex.org/W3046580973","https://openalex.org/W3090171308","https://openalex.org/W3125566655","https://openalex.org/W3126326305","https://openalex.org/W3164716914","https://openalex.org/W3168436232","https://openalex.org/W3209044105","https://openalex.org/W4200279547","https://openalex.org/W4210710803","https://openalex.org/W4291302291","https://openalex.org/W4295905361","https://openalex.org/W4309452766"],"related_works":["https://openalex.org/W4308805210","https://openalex.org/W2004102775","https://openalex.org/W2127264463","https://openalex.org/W3164924009","https://openalex.org/W1854810044","https://openalex.org/W2245879397","https://openalex.org/W2553548503","https://openalex.org/W3045995536","https://openalex.org/W2060851522","https://openalex.org/W2156224181"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}