{"id":"https://openalex.org/W4286377541","doi":"https://doi.org/10.1007/978-981-19-4549-6_6","title":"Predicting Drug-Target Interactions Binding Affinity by Using Dual Updating Multi-task Learning","display_name":"Predicting Drug-Target Interactions Binding Affinity by Using Dual Updating Multi-task Learning","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4286377541","doi":"https://doi.org/10.1007/978-981-19-4549-6_6"},"language":"en","primary_location":{"id":"doi:10.1007/978-981-19-4549-6_6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-981-19-4549-6_6","pdf_url":null,"source":{"id":"https://openalex.org/S2764900261","display_name":"Communications in computer and information science","issn_l":"1865-0929","issn":["1865-0929","1865-0937"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Communications in Computer and Information Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5035091685","display_name":"Chengyu Shi","orcid":"https://orcid.org/0000-0001-5146-8461"},"institutions":[{"id":"https://openalex.org/I37796252","display_name":"Beijing University of Technology","ror":"https://ror.org/037b1pp87","country_code":"CN","type":"education","lineage":["https://openalex.org/I37796252"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Chengyu Shi","raw_affiliation_strings":["Beijing University of Technology, Beijing, 100020, China"],"affiliations":[{"raw_affiliation_string":"Beijing University of Technology, Beijing, 100020, China","institution_ids":["https://openalex.org/I37796252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036375505","display_name":"Shaofu Lin","orcid":"https://orcid.org/0000-0002-3653-6531"},"institutions":[{"id":"https://openalex.org/I37796252","display_name":"Beijing University of Technology","ror":"https://ror.org/037b1pp87","country_code":"CN","type":"education","lineage":["https://openalex.org/I37796252"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Shaofu Lin","raw_affiliation_strings":["Beijing University of Technology, Beijing, 100020, China"],"affiliations":[{"raw_affiliation_string":"Beijing University of Technology, Beijing, 100020, China","institution_ids":["https://openalex.org/I37796252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100765306","display_name":"Jianhui Chen","orcid":"https://orcid.org/0000-0001-6501-9819"},"institutions":[{"id":"https://openalex.org/I37796252","display_name":"Beijing University of Technology","ror":"https://ror.org/037b1pp87","country_code":"CN","type":"education","lineage":["https://openalex.org/I37796252"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianhui Chen","raw_affiliation_strings":["Beijing University of Technology, Beijing, 100020, China"],"affiliations":[{"raw_affiliation_string":"Beijing University of Technology, Beijing, 100020, China","institution_ids":["https://openalex.org/I37796252"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082529341","display_name":"M. Wang","orcid":"https://orcid.org/0000-0003-4062-710X"},"institutions":[{"id":"https://openalex.org/I37796252","display_name":"Beijing University of Technology","ror":"https://ror.org/037b1pp87","country_code":"CN","type":"education","lineage":["https://openalex.org/I37796252"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Mengzhen Wang","raw_affiliation_strings":["Beijing University of Technology, Beijing, 100020, China"],"affiliations":[{"raw_affiliation_string":"Beijing University of Technology, Beijing, 100020, China","institution_ids":["https://openalex.org/I37796252"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050964791","display_name":"Qingcai Gao","orcid":null},"institutions":[{"id":"https://openalex.org/I37796252","display_name":"Beijing University of Technology","ror":"https://ror.org/037b1pp87","country_code":"CN","type":"education","lineage":["https://openalex.org/I37796252"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qingcai Gao","raw_affiliation_strings":["Beijing University of Technology, Beijing, 100020, China"],"affiliations":[{"raw_affiliation_string":"Beijing University of Technology, Beijing, 100020, China","institution_ids":["https://openalex.org/I37796252"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5035091685"],"corresponding_institution_ids":["https://openalex.org/I37796252"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.257505,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"66","last_page":"76"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.9909999966621399,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10911","display_name":"Chemical Synthesis and Analysis","score":0.9677000045776367,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/task","display_name":"Task (project management)","score":0.7683309316635132},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6899612545967102},{"id":"https://openalex.org/keywords/drug-target","display_name":"Drug target","score":0.65653395652771},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.652825653553009},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.6043847799301147},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.5915859341621399},{"id":"https://openalex.org/keywords/dual","display_name":"Dual (grammatical number)","score":0.5569258332252502},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.5352334380149841},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.48150381445884705},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.4355221390724182},{"id":"https://openalex.org/keywords/deep-neural-networks","display_name":"Deep neural networks","score":0.4342448115348816},{"id":"https://openalex.org/keywords/field","display_name":"Field (mathematics)","score":0.4239104986190796},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.15449458360671997},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.10689038038253784},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.0999041497707367},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.08189001679420471},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.0713062584400177}],"concepts":[{"id":"https://openalex.org/C2780451532","wikidata":"https://www.wikidata.org/wiki/Q759676","display_name":"Task (project management)","level":2,"score":0.7683309316635132},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6899612545967102},{"id":"https://openalex.org/C2989108626","wikidata":"https://www.wikidata.org/wiki/Q904407","display_name":"Drug target","level":2,"score":0.65653395652771},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.652825653553009},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.6043847799301147},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.5915859341621399},{"id":"https://openalex.org/C2780980858","wikidata":"https://www.wikidata.org/wiki/Q110022","display_name":"Dual (grammatical number)","level":2,"score":0.5569258332252502},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.5352334380149841},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.48150381445884705},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.4355221390724182},{"id":"https://openalex.org/C2984842247","wikidata":"https://www.wikidata.org/wiki/Q197536","display_name":"Deep neural networks","level":3,"score":0.4342448115348816},{"id":"https://openalex.org/C9652623","wikidata":"https://www.wikidata.org/wiki/Q190109","display_name":"Field (mathematics)","level":2,"score":0.4239104986190796},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.15449458360671997},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.10689038038253784},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.0999041497707367},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.08189001679420471},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0713062584400177},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.0},{"id":"https://openalex.org/C201995342","wikidata":"https://www.wikidata.org/wiki/Q682496","display_name":"Systems engineering","level":1,"score":0.0},{"id":"https://openalex.org/C124952713","wikidata":"https://www.wikidata.org/wiki/Q8242","display_name":"Literature","level":1,"score":0.0},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C111919701","wikidata":"https://www.wikidata.org/wiki/Q9135","display_name":"Operating system","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-981-19-4549-6_6","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-981-19-4549-6_6","pdf_url":null,"source":{"id":"https://openalex.org/S2764900261","display_name":"Communications in computer and information science","issn_l":"1865-0929","issn":["1865-0929","1865-0937"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Communications in Computer and Information Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1757990252","https://openalex.org/W1888005072","https://openalex.org/W2035585923","https://openalex.org/W2086286404","https://openalex.org/W2138072853","https://openalex.org/W2138274020","https://openalex.org/W2147526198","https://openalex.org/W2173027866","https://openalex.org/W2785947426","https://openalex.org/W2791796577","https://openalex.org/W2793951981","https://openalex.org/W2955251621","https://openalex.org/W2980789587","https://openalex.org/W3015490653","https://openalex.org/W3105705953","https://openalex.org/W3127104022","https://openalex.org/W3197123494","https://openalex.org/W6702248584","https://openalex.org/W6830646645"],"related_works":["https://openalex.org/W4210854019","https://openalex.org/W1629725936","https://openalex.org/W4288754364","https://openalex.org/W4308734192","https://openalex.org/W4309130954","https://openalex.org/W4293355921","https://openalex.org/W2131463865","https://openalex.org/W4312831135","https://openalex.org/W3216512054","https://openalex.org/W2936852653"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}