{"id":"https://openalex.org/W149094378","doi":"https://doi.org/10.1007/978-3-642-37137-0_1","title":"Integrative Approaches for Drug Discovery \u2013 PPAR Gamma as a Case Study","display_name":"Integrative Approaches for Drug Discovery \u2013 PPAR Gamma as a Case Study","publication_year":2013,"publication_date":"2013-01-01","ids":{"openalex":"https://openalex.org/W149094378","doi":"https://doi.org/10.1007/978-3-642-37137-0_1","mag":"149094378"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-37137-0_1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-37137-0_1","pdf_url":null,"source":{"id":"https://openalex.org/S2764461748","display_name":"Studies in computational intelligence","issn_l":"1860-949X","issn":["1860-949X","1860-9503"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Computational Intelligence","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043323519","display_name":"Meena Kishore Sakharkar","orcid":"https://orcid.org/0000-0002-9289-3314"},"institutions":[{"id":"https://openalex.org/I146399215","display_name":"University of Tsukuba","ror":"https://ror.org/02956yf07","country_code":"JP","type":"education","lineage":["https://openalex.org/I146399215"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Meena Kishore Sakharkar","raw_affiliation_strings":["University of Tsukuba, Tsukuba, Japan"],"affiliations":[{"raw_affiliation_string":"University of Tsukuba, Tsukuba, Japan","institution_ids":["https://openalex.org/I146399215"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5043323519"],"corresponding_institution_ids":["https://openalex.org/I146399215"],"apc_list":null,"apc_paid":null,"fwci":0.5802,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.68005928,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"1"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11072","display_name":"Peroxisome Proliferator-Activated Receptors","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism","score":0.9807999730110168,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/peroxisome-proliferator-activated-receptor","display_name":"Peroxisome proliferator-activated receptor","score":0.6582587361335754},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"Drug discovery","score":0.6351737976074219},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5938246250152588},{"id":"https://openalex.org/keywords/disease","display_name":"Disease","score":0.5824339985847473},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5574547648429871},{"id":"https://openalex.org/keywords/nuclear-receptor","display_name":"Nuclear receptor","score":0.5331287384033203},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5201435685157776},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.5092176198959351},{"id":"https://openalex.org/keywords/drug-development","display_name":"Drug development","score":0.47326353192329407},{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.45403051376342773},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.4406070113182068},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.43702417612075806},{"id":"https://openalex.org/keywords/drug","display_name":"Drug","score":0.3801037073135376},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.36979568004608154},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.28986871242523193},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.24988457560539246},{"id":"https://openalex.org/keywords/pharmacology","display_name":"Pharmacology","score":0.23392677307128906},{"id":"https://openalex.org/keywords/transcription-factor","display_name":"Transcription factor","score":0.18880465626716614},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.1379464566707611}],"concepts":[{"id":"https://openalex.org/C187345961","wikidata":"https://www.wikidata.org/wiki/Q419629","display_name":"Peroxisome proliferator-activated receptor","level":3,"score":0.6582587361335754},{"id":"https://openalex.org/C74187038","wikidata":"https://www.wikidata.org/wiki/Q1418791","display_name":"Drug discovery","level":2,"score":0.6351737976074219},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5938246250152588},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5824339985847473},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5574547648429871},{"id":"https://openalex.org/C63932345","wikidata":"https://www.wikidata.org/wiki/Q422500","display_name":"Nuclear receptor","level":4,"score":0.5331287384033203},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5201435685157776},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.5092176198959351},{"id":"https://openalex.org/C64903051","wikidata":"https://www.wikidata.org/wiki/Q2198549","display_name":"Drug development","level":3,"score":0.47326353192329407},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.45403051376342773},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.4406070113182068},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.43702417612075806},{"id":"https://openalex.org/C2780035454","wikidata":"https://www.wikidata.org/wiki/Q8386","display_name":"Drug","level":2,"score":0.3801037073135376},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.36979568004608154},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.28986871242523193},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24988457560539246},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.23392677307128906},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.18880465626716614},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1379464566707611}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-642-37137-0_1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-37137-0_1","pdf_url":null,"source":{"id":"https://openalex.org/S2764461748","display_name":"Studies in computational intelligence","issn_l":"1860-949X","issn":["1860-949X","1860-9503"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Studies in Computational Intelligence","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2057155961","https://openalex.org/W2094628134","https://openalex.org/W2898595765","https://openalex.org/W2096630686","https://openalex.org/W4307501484","https://openalex.org/W2921046411","https://openalex.org/W2061080379","https://openalex.org/W2025424979","https://openalex.org/W2228293239","https://openalex.org/W149094378"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2014,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}