{"id":"https://openalex.org/W2172811046","doi":"https://doi.org/10.1007/978-3-642-30191-9_4","title":"Reconstruction of Transcription Regulatory Networks by Stability-Based Network Component Analysis","display_name":"Reconstruction of Transcription Regulatory Networks by Stability-Based Network Component Analysis","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W2172811046","doi":"https://doi.org/10.1007/978-3-642-30191-9_4","mag":"2172811046"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-30191-9_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-30191-9_4","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100330034","display_name":"Xi Chen","orcid":"https://orcid.org/0000-0003-2648-3146"},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xi Chen","raw_affiliation_strings":["Department of Electrical & Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA, 22203, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical & Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA, 22203, USA","institution_ids":["https://openalex.org/I859038795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100337669","display_name":"Chen Wang","orcid":"https://orcid.org/0000-0003-2638-3081"},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chen Wang","raw_affiliation_strings":["Department of Electrical & Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA, 22203, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical & Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA, 22203, USA","institution_ids":["https://openalex.org/I859038795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001200228","display_name":"Ayesha N. Shajahan\u2010Haq","orcid":"https://orcid.org/0000-0001-7616-320X"},"institutions":[{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I2799903593","display_name":"Georgetown University Medical Center","ror":"https://ror.org/00hjz7x27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799903593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ayesha N. Shajahan","raw_affiliation_strings":["Lombardi Comprehensive Cancer Center and Department of Oncology, Georgetown University, Washington, DC, USA, 20057"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lombardi Comprehensive Cancer Center and Department of Oncology, Georgetown University, Washington, DC, USA, 20057","institution_ids":["https://openalex.org/I2799903593","https://openalex.org/I184565670"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032949456","display_name":"Rebecca B. Riggins","orcid":"https://orcid.org/0000-0002-1555-4431"},"institutions":[{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I2799903593","display_name":"Georgetown University Medical Center","ror":"https://ror.org/00hjz7x27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799903593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rebecca B. Riggins","raw_affiliation_strings":["Lombardi Comprehensive Cancer Center and Department of Oncology, Georgetown University, Washington, DC, USA, 20057"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lombardi Comprehensive Cancer Center and Department of Oncology, Georgetown University, Washington, DC, USA, 20057","institution_ids":["https://openalex.org/I2799903593","https://openalex.org/I184565670"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011322600","display_name":"Robert Clarke","orcid":"https://orcid.org/0000-0002-9278-0854"},"institutions":[{"id":"https://openalex.org/I184565670","display_name":"Georgetown University","ror":"https://ror.org/05vzafd60","country_code":"US","type":"education","lineage":["https://openalex.org/I184565670"]},{"id":"https://openalex.org/I2799903593","display_name":"Georgetown University Medical Center","ror":"https://ror.org/00hjz7x27","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2799903593"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Robert Clarke","raw_affiliation_strings":["Lombardi Comprehensive Cancer Center and Department of Oncology, Georgetown University, Washington, DC, USA, 20057"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lombardi Comprehensive Cancer Center and Department of Oncology, Georgetown University, Washington, DC, USA, 20057","institution_ids":["https://openalex.org/I2799903593","https://openalex.org/I184565670"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5101536121","display_name":"Jianhua Xuan","orcid":"https://orcid.org/0000-0001-7256-1374"},"institutions":[{"id":"https://openalex.org/I859038795","display_name":"Virginia Tech","ror":"https://ror.org/02smfhw86","country_code":"US","type":"education","lineage":["https://openalex.org/I859038795"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jianhua Xuan","raw_affiliation_strings":["Department of Electrical & Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA, 22203, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical & Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA, 22203, USA","institution_ids":["https://openalex.org/I859038795"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.13217403,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"36","last_page":"47"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9986000061035156,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9962000250816345,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7154614925384521},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.611043393611908},{"id":"https://openalex.org/keywords/inference","display_name":"Inference","score":0.5785988569259644},{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.5682571530342102},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.5264866352081299},{"id":"https://openalex.org/keywords/transcription-factor","display_name":"Transcription factor","score":0.42840176820755005},{"id":"https://openalex.org/keywords/motif","display_name":"Motif (music)","score":0.42186418175697327},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3601250648498535},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3470829129219055},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.32674479484558105},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3146618604660034},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.2774990200996399},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.21725350618362427},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.14723804593086243}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7154614925384521},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.611043393611908},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.5785988569259644},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.5682571530342102},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.5264866352081299},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.42840176820755005},{"id":"https://openalex.org/C32276052","wikidata":"https://www.wikidata.org/wiki/Q908349","display_name":"Motif (music)","level":2,"score":0.42186418175697327},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3601250648498535},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3470829129219055},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.32674479484558105},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3146618604660034},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.2774990200996399},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21725350618362427},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.14723804593086243},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C24890656","wikidata":"https://www.wikidata.org/wiki/Q82811","display_name":"Acoustics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/978-3-642-30191-9_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-30191-9_4","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},{"id":"pmh:oai:europepmc.org:2878907","is_oa":false,"landing_page_url":"http://europepmc.org/articles/PMC3652899","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4099999964237213,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":22,"referenced_works":["https://openalex.org/W1982168843","https://openalex.org/W1992614239","https://openalex.org/W2051559956","https://openalex.org/W2068000365","https://openalex.org/W2069645361","https://openalex.org/W2070672503","https://openalex.org/W2076186971","https://openalex.org/W2082926700","https://openalex.org/W2094036688","https://openalex.org/W2098607364","https://openalex.org/W2107209294","https://openalex.org/W2115722741","https://openalex.org/W2133446381","https://openalex.org/W2135030836","https://openalex.org/W2136305830","https://openalex.org/W2139324860","https://openalex.org/W2150533948","https://openalex.org/W2153733894","https://openalex.org/W2154522528","https://openalex.org/W2164963884","https://openalex.org/W2285306916","https://openalex.org/W4248058040"],"related_works":["https://openalex.org/W3170299350","https://openalex.org/W2368410102","https://openalex.org/W2605676258","https://openalex.org/W2368037387","https://openalex.org/W2950199998","https://openalex.org/W2560421304","https://openalex.org/W2951387065","https://openalex.org/W2134575910","https://openalex.org/W4385727351","https://openalex.org/W4306798985"],"abstract_inverted_index":null,"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}