{"id":"https://openalex.org/W1563766529","doi":"https://doi.org/10.1007/978-3-642-28067-2_7","title":"Computational Modeling and Verification of Signaling Pathways in Cancer","display_name":"Computational Modeling and Verification of Signaling Pathways in Cancer","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W1563766529","doi":"https://doi.org/10.1007/978-3-642-28067-2_7","mag":"1563766529"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-28067-2_7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-28067-2_7","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5030155062","display_name":"Haijun Gong","orcid":"https://orcid.org/0000-0003-1666-1674"},"institutions":[{"id":"https://openalex.org/I4210156583","display_name":"Laboratoire d'Informatique de Paris-Nord","ror":"https://ror.org/05g1zjw44","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I4210091279","https://openalex.org/I4210156583","https://openalex.org/I4210159245"]},{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["FR","US"],"is_corresponding":true,"raw_author_name":"Haijun Gong","raw_affiliation_strings":["Computer Science Department, Carnegie Mellon University, Pittsburgh, USA","Computer Science Department, Carnegie-Mellon University, Pittsburgh, Pa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science Department, Carnegie Mellon University, Pittsburgh, USA","institution_ids":["https://openalex.org/I74973139"]},{"raw_affiliation_string":"Computer Science Department, Carnegie-Mellon University, Pittsburgh, Pa","institution_ids":["https://openalex.org/I74973139","https://openalex.org/I4210156583"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054022139","display_name":"Paolo Zuliani","orcid":"https://orcid.org/0000-0001-6033-5919"},"institutions":[{"id":"https://openalex.org/I4210156583","display_name":"Laboratoire d'Informatique de Paris-Nord","ror":"https://ror.org/05g1zjw44","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I4210091279","https://openalex.org/I4210156583","https://openalex.org/I4210159245"]},{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["FR","US"],"is_corresponding":false,"raw_author_name":"Paolo Zuliani","raw_affiliation_strings":["Computer Science Department, Carnegie Mellon University, Pittsburgh, USA","Computer Science Department, Carnegie-Mellon University, Pittsburgh, Pa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science Department, Carnegie Mellon University, Pittsburgh, USA","institution_ids":["https://openalex.org/I74973139"]},{"raw_affiliation_string":"Computer Science Department, Carnegie-Mellon University, Pittsburgh, Pa","institution_ids":["https://openalex.org/I74973139","https://openalex.org/I4210156583"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027580280","display_name":"Anvesh Komuravelli","orcid":"https://orcid.org/0000-0002-0927-2075"},"institutions":[{"id":"https://openalex.org/I4210156583","display_name":"Laboratoire d'Informatique de Paris-Nord","ror":"https://ror.org/05g1zjw44","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I4210091279","https://openalex.org/I4210156583","https://openalex.org/I4210159245"]},{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["FR","US"],"is_corresponding":false,"raw_author_name":"Anvesh Komuravelli","raw_affiliation_strings":["Computer Science Department, Carnegie Mellon University, Pittsburgh, USA","Computer Science Department, Carnegie-Mellon University, Pittsburgh, Pa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science Department, Carnegie Mellon University, Pittsburgh, USA","institution_ids":["https://openalex.org/I74973139"]},{"raw_affiliation_string":"Computer Science Department, Carnegie-Mellon University, Pittsburgh, Pa","institution_ids":["https://openalex.org/I74973139","https://openalex.org/I4210156583"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020336186","display_name":"James R. Faeder","orcid":"https://orcid.org/0000-0001-8127-609X"},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James R. Faeder","raw_affiliation_strings":["Department of Computational Biology, University of Pittsburgh, Pittsburgh, USA","Department of Computational Biology, University of Pittsburgh, Pittsburgh, PA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Computational Biology, University of Pittsburgh, Pittsburgh, USA","institution_ids":["https://openalex.org/I170201317"]},{"raw_affiliation_string":"Department of Computational Biology, University of Pittsburgh, Pittsburgh, PA","institution_ids":["https://openalex.org/I170201317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5105356861","display_name":"Edmund M. Clarke","orcid":null},"institutions":[{"id":"https://openalex.org/I4210156583","display_name":"Laboratoire d'Informatique de Paris-Nord","ror":"https://ror.org/05g1zjw44","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I4210091279","https://openalex.org/I4210156583","https://openalex.org/I4210159245"]},{"id":"https://openalex.org/I74973139","display_name":"Carnegie Mellon University","ror":"https://ror.org/05x2bcf33","country_code":"US","type":"education","lineage":["https://openalex.org/I74973139"]}],"countries":["FR","US"],"is_corresponding":false,"raw_author_name":"Edmund M. Clarke","raw_affiliation_strings":["Computer Science Department, Carnegie Mellon University, Pittsburgh, USA","Computer Science Department, Carnegie-Mellon University, Pittsburgh, Pa"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Computer Science Department, Carnegie Mellon University, Pittsburgh, USA","institution_ids":["https://openalex.org/I74973139"]},{"raw_affiliation_string":"Computer Science Department, Carnegie-Mellon University, Pittsburgh, Pa","institution_ids":["https://openalex.org/I74973139","https://openalex.org/I4210156583"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5030155062"],"corresponding_institution_ids":["https://openalex.org/I4210156583","https://openalex.org/I74973139"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":14.5746,"has_fulltext":false,"cited_by_count":25,"citation_normalized_percentile":{"value":0.98743268,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"117","last_page":"135"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11142","display_name":"Advanced Glycation End Products research","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11142","display_name":"Advanced Glycation End Products research","score":0.9966999888420105,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11591","display_name":"NF-\u03baB Signaling Pathways","score":0.9965000152587891,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects","score":0.9939000010490417,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/crosstalk","display_name":"Crosstalk","score":0.7775129079818726},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6329300403594971},{"id":"https://openalex.org/keywords/hmgb1","display_name":"HMGB1","score":0.42663976550102234},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3385465741157532},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.2371431589126587},{"id":"https://openalex.org/keywords/inflammation","display_name":"Inflammation","score":0.22110649943351746},{"id":"https://openalex.org/keywords/electronic-engineering","display_name":"Electronic engineering","score":0.14223888516426086},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.11788377165794373}],"concepts":[{"id":"https://openalex.org/C169822122","wikidata":"https://www.wikidata.org/wiki/Q230187","display_name":"Crosstalk","level":2,"score":0.7775129079818726},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6329300403594971},{"id":"https://openalex.org/C2780545709","wikidata":"https://www.wikidata.org/wiki/Q21130552","display_name":"HMGB1","level":3,"score":0.42663976550102234},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3385465741157532},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2371431589126587},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.22110649943351746},{"id":"https://openalex.org/C24326235","wikidata":"https://www.wikidata.org/wiki/Q126095","display_name":"Electronic engineering","level":1,"score":0.14223888516426086},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.11788377165794373},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/978-3-642-28067-2_7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-28067-2_7","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},{"id":"pmh:oai:iris.uniroma1.it:11573/1681075","is_oa":false,"landing_page_url":"https://hdl.handle.net/11573/1681075","pdf_url":null,"source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":55,"referenced_works":["https://openalex.org/W339627914","https://openalex.org/W1517251498","https://openalex.org/W1569248486","https://openalex.org/W1590804833","https://openalex.org/W1597756947","https://openalex.org/W1606860353","https://openalex.org/W1641228030","https://openalex.org/W1650797637","https://openalex.org/W1945598588","https://openalex.org/W1967625949","https://openalex.org/W1969853331","https://openalex.org/W1979634817","https://openalex.org/W1982528660","https://openalex.org/W1990674638","https://openalex.org/W1992708996","https://openalex.org/W2008819839","https://openalex.org/W2008887283","https://openalex.org/W2013304729","https://openalex.org/W2016000295","https://openalex.org/W2018653121","https://openalex.org/W2019860010","https://openalex.org/W2024918098","https://openalex.org/W2025970479","https://openalex.org/W2033194496","https://openalex.org/W2034269086","https://openalex.org/W2042321087","https://openalex.org/W2044737524","https://openalex.org/W2046290067","https://openalex.org/W2051312368","https://openalex.org/W2061773314","https://openalex.org/W2067971887","https://openalex.org/W2069941324","https://openalex.org/W2076526469","https://openalex.org/W2080719056","https://openalex.org/W2086390177","https://openalex.org/W2089586229","https://openalex.org/W2093803300","https://openalex.org/W2101153911","https://openalex.org/W2113126782","https://openalex.org/W2121567796","https://openalex.org/W2124810679","https://openalex.org/W2125937596","https://openalex.org/W2127683740","https://openalex.org/W2141997480","https://openalex.org/W2143998429","https://openalex.org/W2149139293","https://openalex.org/W2152105216","https://openalex.org/W2161081924","https://openalex.org/W2166422915","https://openalex.org/W2170498206","https://openalex.org/W2175715045","https://openalex.org/W2340735175","https://openalex.org/W2361838659","https://openalex.org/W2913459036","https://openalex.org/W4244457856"],"related_works":["https://openalex.org/W2748952813","https://openalex.org/W2965511311","https://openalex.org/W2157119957","https://openalex.org/W2064185357","https://openalex.org/W2016169910","https://openalex.org/W3158711521","https://openalex.org/W3030923191","https://openalex.org/W2123714571","https://openalex.org/W2376849124","https://openalex.org/W2133054993"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":6},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-04-28T14:05:53.105641","created_date":"2025-10-10T00:00:00"}