{"id":"https://openalex.org/W206420962","doi":"https://doi.org/10.1007/978-3-642-24553-4_35","title":"Do MicroRNAs Preferentially Target the Genes with Low DNA Methylation Level at the Promoter Region?","display_name":"Do MicroRNAs Preferentially Target the Genes with Low DNA Methylation Level at the Promoter Region?","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W206420962","doi":"https://doi.org/10.1007/978-3-642-24553-4_35","mag":"206420962"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-24553-4_35","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-24553-4_35","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048196927","display_name":"Zhixi Su","orcid":"https://orcid.org/0000-0002-4881-1238"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhixi Su","raw_affiliation_strings":["Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065943710","display_name":"Junfeng Xia","orcid":"https://orcid.org/0000-0003-3024-1705"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Junfeng Xia","raw_affiliation_strings":["Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA","institution_ids":["https://openalex.org/I200719446"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006688612","display_name":"Zhongming Zhao","orcid":"https://orcid.org/0000-0002-3477-0914"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zhongming Zhao","raw_affiliation_strings":["Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA","Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA","Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Informatics, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Department of Cancer Biology, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA","institution_ids":["https://openalex.org/I200719446"]},{"raw_affiliation_string":"Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, 37232, USA","institution_ids":["https://openalex.org/I200719446"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I200719446"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"253","last_page":"258"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11482","display_name":"RNA modifications and cancer","score":0.9912999868392944,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dna-methylation","display_name":"DNA methylation","score":0.775353729724884},{"id":"https://openalex.org/keywords/epigenetics","display_name":"Epigenetics","score":0.6870803236961365},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.6756277084350586},{"id":"https://openalex.org/keywords/epigenetics-of-physical-exercise","display_name":"Epigenetics of physical exercise","score":0.6504856944084167},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.6257858872413635},{"id":"https://openalex.org/keywords/gene-silencing","display_name":"Gene silencing","score":0.6150939464569092},{"id":"https://openalex.org/keywords/promoter","display_name":"Promoter","score":0.5802177786827087},{"id":"https://openalex.org/keywords/methylation","display_name":"Methylation","score":0.5550695061683655},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5340505838394165},{"id":"https://openalex.org/keywords/regulation-of-gene-expression","display_name":"Regulation of gene expression","score":0.5329927206039429},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.5145630240440369},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.37304237484931946}],"concepts":[{"id":"https://openalex.org/C190727270","wikidata":"https://www.wikidata.org/wiki/Q874745","display_name":"DNA methylation","level":4,"score":0.775353729724884},{"id":"https://openalex.org/C41091548","wikidata":"https://www.wikidata.org/wiki/Q26939","display_name":"Epigenetics","level":3,"score":0.6870803236961365},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.6756277084350586},{"id":"https://openalex.org/C37080517","wikidata":"https://www.wikidata.org/wiki/Q18353747","display_name":"Epigenetics of physical exercise","level":5,"score":0.6504856944084167},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6257858872413635},{"id":"https://openalex.org/C119056186","wikidata":"https://www.wikidata.org/wiki/Q1431332","display_name":"Gene silencing","level":3,"score":0.6150939464569092},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.5802177786827087},{"id":"https://openalex.org/C33288867","wikidata":"https://www.wikidata.org/wiki/Q518328","display_name":"Methylation","level":3,"score":0.5550695061683655},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5340505838394165},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.5329927206039429},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5145630240440369},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.37304237484931946}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-642-24553-4_35","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-24553-4_35","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5799999833106995,"id":"https://metadata.un.org/sdg/2","display_name":"Zero hunger"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W1598044505","https://openalex.org/W1966489066","https://openalex.org/W1967841068","https://openalex.org/W1972092183","https://openalex.org/W1975437957","https://openalex.org/W1983611264","https://openalex.org/W2004172747","https://openalex.org/W2024848067","https://openalex.org/W2046241907","https://openalex.org/W2055742349","https://openalex.org/W2059099579","https://openalex.org/W2067151470","https://openalex.org/W2070571588","https://openalex.org/W2107038650","https://openalex.org/W2107983332","https://openalex.org/W2113588666","https://openalex.org/W2128874237","https://openalex.org/W2146453000","https://openalex.org/W2160226189"],"related_works":["https://openalex.org/W2106340242","https://openalex.org/W2084207260","https://openalex.org/W4290034632","https://openalex.org/W2150628237","https://openalex.org/W2123238153","https://openalex.org/W2581702729","https://openalex.org/W2014085481","https://openalex.org/W3107516814","https://openalex.org/W2167996825","https://openalex.org/W1985855821"],"abstract_inverted_index":null,"counts_by_year":[{"year":2012,"cited_by_count":1}],"updated_date":"2026-07-14T23:27:15.235271","created_date":"2025-10-10T00:00:00"}