{"id":"https://openalex.org/W2234304375","doi":"https://doi.org/10.1007/978-3-642-20036-6_4","title":"Causal Reasoning on Biological Networks: Interpreting Transcriptional Changes","display_name":"Causal Reasoning on Biological Networks: Interpreting Transcriptional Changes","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W2234304375","doi":"https://doi.org/10.1007/978-3-642-20036-6_4","mag":"2234304375"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-20036-6_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-20036-6_4","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065939739","display_name":"Leonid Chindelevitch","orcid":"https://orcid.org/0000-0002-6619-6013"},"institutions":[{"id":"https://openalex.org/I180857899","display_name":"Pfizer (United States)","ror":"https://ror.org/01xdqrp08","country_code":"US","type":"company","lineage":["https://openalex.org/I180857899"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Leonid Chindelevitch","raw_affiliation_strings":["Computational Sciences Center of Emphasis, Pfizer Worldwide Research and Development, Cambridge, MA, USA"],"affiliations":[{"raw_affiliation_string":"Computational Sciences Center of Emphasis, Pfizer Worldwide Research and Development, Cambridge, MA, USA","institution_ids":["https://openalex.org/I180857899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038688193","display_name":"Daniel Ziemek","orcid":null},"institutions":[{"id":"https://openalex.org/I180857899","display_name":"Pfizer (United States)","ror":"https://ror.org/01xdqrp08","country_code":"US","type":"company","lineage":["https://openalex.org/I180857899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Daniel Ziemek","raw_affiliation_strings":["Computational Sciences Center of Emphasis, Pfizer Worldwide Research and Development, Cambridge, MA, USA"],"affiliations":[{"raw_affiliation_string":"Computational Sciences Center of Emphasis, Pfizer Worldwide Research and Development, Cambridge, MA, USA","institution_ids":["https://openalex.org/I180857899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054882931","display_name":"Ahmed Enayetallah","orcid":null},"institutions":[{"id":"https://openalex.org/I180857899","display_name":"Pfizer (United States)","ror":"https://ror.org/01xdqrp08","country_code":"US","type":"company","lineage":["https://openalex.org/I180857899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ahmed Enayetallah","raw_affiliation_strings":["Compound Safety Prediction, Pfizer Worldwide Medicinal Chemistry, Groton, CT, USA"],"affiliations":[{"raw_affiliation_string":"Compound Safety Prediction, Pfizer Worldwide Medicinal Chemistry, Groton, CT, USA","institution_ids":["https://openalex.org/I180857899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051778273","display_name":"Ranjit Randhawa","orcid":"https://orcid.org/0000-0003-1516-7674"},"institutions":[{"id":"https://openalex.org/I180857899","display_name":"Pfizer (United States)","ror":"https://ror.org/01xdqrp08","country_code":"US","type":"company","lineage":["https://openalex.org/I180857899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ranjit Randhawa","raw_affiliation_strings":["Computational Sciences Center of Emphasis, Pfizer Worldwide Research and Development, Cambridge, MA, USA"],"affiliations":[{"raw_affiliation_string":"Computational Sciences Center of Emphasis, Pfizer Worldwide Research and Development, Cambridge, MA, USA","institution_ids":["https://openalex.org/I180857899"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033816209","display_name":"Ben S. Sidders","orcid":"https://orcid.org/0000-0003-2733-3078"},"institutions":[{"id":"https://openalex.org/I189718659","display_name":"Pfizer (United Kingdom)","ror":"https://ror.org/04x4v8p40","country_code":"GB","type":"company","lineage":["https://openalex.org/I180857899","https://openalex.org/I189718659"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Ben Sidders","raw_affiliation_strings":["eBiology, Pfizer Worldwide Research and Development, Sandwich, Kent, UK"],"affiliations":[{"raw_affiliation_string":"eBiology, Pfizer Worldwide Research and Development, Sandwich, Kent, UK","institution_ids":["https://openalex.org/I189718659"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038589077","display_name":"Christoph Brockel","orcid":null},"institutions":[{"id":"https://openalex.org/I180857899","display_name":"Pfizer (United States)","ror":"https://ror.org/01xdqrp08","country_code":"US","type":"company","lineage":["https://openalex.org/I180857899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Christoph Brockel","raw_affiliation_strings":["Translational and Bioinformatics, Pfizer Business Technologies, Cambridge, MA, USA"],"affiliations":[{"raw_affiliation_string":"Translational and Bioinformatics, Pfizer Business Technologies, Cambridge, MA, USA","institution_ids":["https://openalex.org/I180857899"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089308999","display_name":"Enoch S. Huang","orcid":null},"institutions":[{"id":"https://openalex.org/I180857899","display_name":"Pfizer (United States)","ror":"https://ror.org/01xdqrp08","country_code":"US","type":"company","lineage":["https://openalex.org/I180857899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Enoch Huang","raw_affiliation_strings":["Computational Sciences Center of Emphasis, Pfizer Worldwide Research and Development, Cambridge, MA, USA"],"affiliations":[{"raw_affiliation_string":"Computational Sciences Center of Emphasis, Pfizer Worldwide Research and Development, Cambridge, MA, USA","institution_ids":["https://openalex.org/I180857899"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":7,"corresponding_author_ids":["https://openalex.org/A5065939739"],"corresponding_institution_ids":["https://openalex.org/I180857899"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":10.066,"has_fulltext":false,"cited_by_count":55,"citation_normalized_percentile":{"value":0.98472669,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"34","last_page":"37"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11710","display_name":"Biomedical Text Mining and Ontologies","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9958999752998352,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9753999710083008,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pace","display_name":"Pace","score":0.739876389503479},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.696879506111145},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.552652895450592},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.46547362208366394},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.37761688232421875},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3457547724246979},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.3271978497505188},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.32318878173828125},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1702486276626587},{"id":"https://openalex.org/keywords/geography","display_name":"Geography","score":0.06978237628936768}],"concepts":[{"id":"https://openalex.org/C2777526511","wikidata":"https://www.wikidata.org/wiki/Q691543","display_name":"Pace","level":2,"score":0.739876389503479},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.696879506111145},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.552652895450592},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.46547362208366394},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.37761688232421875},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3457547724246979},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3271978497505188},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.32318878173828125},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1702486276626587},{"id":"https://openalex.org/C205649164","wikidata":"https://www.wikidata.org/wiki/Q1071","display_name":"Geography","level":0,"score":0.06978237628936768},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C13280743","wikidata":"https://www.wikidata.org/wiki/Q131089","display_name":"Geodesy","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-642-20036-6_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-20036-6_4","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4300000071525574,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":19,"referenced_works":["https://openalex.org/W84180114","https://openalex.org/W1535641839","https://openalex.org/W1965934331","https://openalex.org/W1984252723","https://openalex.org/W2058451329","https://openalex.org/W2060871791","https://openalex.org/W2061280979","https://openalex.org/W2066902594","https://openalex.org/W2083869247","https://openalex.org/W2096525273","https://openalex.org/W2100083453","https://openalex.org/W2117007075","https://openalex.org/W2128077735","https://openalex.org/W2130307435","https://openalex.org/W2137106034","https://openalex.org/W2144420811","https://openalex.org/W2159675211","https://openalex.org/W2171437346","https://openalex.org/W4231041617"],"related_works":["https://openalex.org/W3107474891","https://openalex.org/W2348097614","https://openalex.org/W4220903678","https://openalex.org/W2355215981","https://openalex.org/W4285266677","https://openalex.org/W2347219288","https://openalex.org/W1480922982","https://openalex.org/W4226300739","https://openalex.org/W2967673535","https://openalex.org/W759646176"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":4},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":3}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}