{"id":"https://openalex.org/W1508810647","doi":"https://doi.org/10.1007/978-3-642-16493-4_52","title":"The Data-Based Mathematical Modeling and Parameter Identification in JAK-STAT Signaling Pathway by Using a Hybrid Evolutionary Algorithm","display_name":"The Data-Based Mathematical Modeling and Parameter Identification in JAK-STAT Signaling Pathway by Using a Hybrid Evolutionary Algorithm","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W1508810647","doi":"https://doi.org/10.1007/978-3-642-16493-4_52","mag":"1508810647"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-16493-4_52","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-16493-4_52","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053538039","display_name":"Wei Zhang","orcid":"https://orcid.org/0000-0001-9298-4497"},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wei Zhang","raw_affiliation_strings":["School of Mathematics and Statistics, Wuhan University, Wuhan, 430072, China"],"affiliations":[{"raw_affiliation_string":"School of Mathematics and Statistics, Wuhan University, Wuhan, 430072, China","institution_ids":["https://openalex.org/I37461747"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009409122","display_name":"Xiufen Zou","orcid":"https://orcid.org/0000-0001-5294-0764"},"institutions":[{"id":"https://openalex.org/I37461747","display_name":"Wuhan University","ror":"https://ror.org/033vjfk17","country_code":"CN","type":"education","lineage":["https://openalex.org/I37461747"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiufen Zou","raw_affiliation_strings":["School of Mathematics and Statistics, Wuhan University, Wuhan, 430072, China"],"affiliations":[{"raw_affiliation_string":"School of Mathematics and Statistics, Wuhan University, Wuhan, 430072, China","institution_ids":["https://openalex.org/I37461747"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5053538039"],"corresponding_institution_ids":["https://openalex.org/I37461747"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.14576585,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"516","last_page":"522"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.991100013256073,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.9894999861717224,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/stat5","display_name":"STAT5","score":0.6622153520584106},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6333515644073486},{"id":"https://openalex.org/keywords/jak-stat-signaling-pathway","display_name":"JAK-STAT signaling pathway","score":0.5749891400337219},{"id":"https://openalex.org/keywords/stat","display_name":"stat","score":0.5274115800857544},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.42328715324401855},{"id":"https://openalex.org/keywords/evolutionary-algorithm","display_name":"Evolutionary algorithm","score":0.41706812381744385},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.41011151671409607},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"Signal transduction","score":0.2741285562515259},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.19398385286331177},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.13275471329689026},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.12354621291160583},{"id":"https://openalex.org/keywords/stat3","display_name":"STAT3","score":0.06381848454475403}],"concepts":[{"id":"https://openalex.org/C2779391668","wikidata":"https://www.wikidata.org/wiki/Q4210018","display_name":"STAT5","level":3,"score":0.6622153520584106},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6333515644073486},{"id":"https://openalex.org/C157333092","wikidata":"https://www.wikidata.org/wiki/Q902835","display_name":"JAK-STAT signaling pathway","level":4,"score":0.5749891400337219},{"id":"https://openalex.org/C2778277574","wikidata":"https://www.wikidata.org/wiki/Q665327","display_name":"stat","level":4,"score":0.5274115800857544},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.42328715324401855},{"id":"https://openalex.org/C159149176","wikidata":"https://www.wikidata.org/wiki/Q14489129","display_name":"Evolutionary algorithm","level":2,"score":0.41706812381744385},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.41011151671409607},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.2741285562515259},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.19398385286331177},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.13275471329689026},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12354621291160583},{"id":"https://openalex.org/C2778923194","wikidata":"https://www.wikidata.org/wiki/Q14912019","display_name":"STAT3","level":3,"score":0.06381848454475403},{"id":"https://openalex.org/C42362537","wikidata":"https://www.wikidata.org/wiki/Q87099740","display_name":"Tyrosine kinase","level":3,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-642-16493-4_52","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-16493-4_52","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1595159159","https://openalex.org/W1660272337","https://openalex.org/W1702674772","https://openalex.org/W1821858011","https://openalex.org/W1978486653","https://openalex.org/W1982528660","https://openalex.org/W2034375425","https://openalex.org/W2039793587","https://openalex.org/W2050661504","https://openalex.org/W2069271582","https://openalex.org/W2081948801","https://openalex.org/W2083802827","https://openalex.org/W2109655246","https://openalex.org/W2116688022","https://openalex.org/W2120019133","https://openalex.org/W2133411540","https://openalex.org/W2143784594","https://openalex.org/W2143894094","https://openalex.org/W2154701841","https://openalex.org/W3146312110"],"related_works":["https://openalex.org/W2899945467","https://openalex.org/W2353430781","https://openalex.org/W1970308473","https://openalex.org/W2905210710","https://openalex.org/W2998564252","https://openalex.org/W1565555611","https://openalex.org/W3216146155","https://openalex.org/W2015394381","https://openalex.org/W2105214962","https://openalex.org/W2916246606"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-01-15T23:16:33.117629","created_date":"2025-10-10T00:00:00"}