{"id":"https://openalex.org/W2122382544","doi":"https://doi.org/10.1007/978-3-642-12683-3_40","title":"A Self-regulatory System of Interlinked Signaling Feedback Loops Controls Mouse Limb Patterning","display_name":"A Self-regulatory System of Interlinked Signaling Feedback Loops Controls Mouse Limb Patterning","publication_year":2010,"publication_date":"2010-01-01","ids":{"openalex":"https://openalex.org/W2122382544","doi":"https://doi.org/10.1007/978-3-642-12683-3_40","mag":"2122382544"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-12683-3_40","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-12683-3_40","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108241811","display_name":"Jean-Denis B\u00e9nazet","orcid":null},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":true,"raw_author_name":"Jean-Denis Benazet","raw_affiliation_strings":["Developmental Genetics, Department of Biomedicine, University of Basel, Switzerland"],"affiliations":[{"raw_affiliation_string":"Developmental Genetics, Department of Biomedicine, University of Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060050578","display_name":"Mirko Bischofberger","orcid":"https://orcid.org/0000-0002-0878-8184"},"institutions":[{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Mirko Bischofberger","raw_affiliation_strings":["Computational Systems Biology Group, Ecole Polytechnique Federale de Lausanne (EPFL), Switzerland"],"affiliations":[{"raw_affiliation_string":"Computational Systems Biology Group, Ecole Polytechnique Federale de Lausanne (EPFL), Switzerland","institution_ids":["https://openalex.org/I5124864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065916083","display_name":"Eva Tiecke","orcid":null},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Eva Tiecke","raw_affiliation_strings":["Developmental Genetics, Department of Biomedicine, University of Basel, Switzerland"],"affiliations":[{"raw_affiliation_string":"Developmental Genetics, Department of Biomedicine, University of Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034954612","display_name":"Alexandre Gonalves","orcid":null},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Alexandre Gonalves","raw_affiliation_strings":["Developmental Genetics, Department of Biomedicine, University of Basel, Switzerland"],"affiliations":[{"raw_affiliation_string":"Developmental Genetics, Department of Biomedicine, University of Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080982128","display_name":"James F. Martin","orcid":"https://orcid.org/0000-0002-7842-9857"},"institutions":[{"id":"https://openalex.org/I125029298","display_name":"Texas A&M Health Science Center","ror":"https://ror.org/01tx6pn92","country_code":"US","type":"education","lineage":["https://openalex.org/I125029298","https://openalex.org/I91045830"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James F. Martin","raw_affiliation_strings":["Texas A&M Health Science Center, Institute of Biosciences and Technology, Houston, USA"],"affiliations":[{"raw_affiliation_string":"Texas A&M Health Science Center, Institute of Biosciences and Technology, Houston, USA","institution_ids":["https://openalex.org/I125029298"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042387218","display_name":"Aime Zuniga","orcid":null},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Aime Zuniga","raw_affiliation_strings":["Developmental Genetics, Department of Biomedicine, University of Basel, Switzerland"],"affiliations":[{"raw_affiliation_string":"Developmental Genetics, Department of Biomedicine, University of Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045537456","display_name":"F\u00e9lix Naef","orcid":"https://orcid.org/0000-0001-9786-3037"},"institutions":[{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Felix Naef","raw_affiliation_strings":["Computational Systems Biology Group, Ecole Polytechnique Federale de Lausanne (EPFL), Switzerland"],"affiliations":[{"raw_affiliation_string":"Computational Systems Biology Group, Ecole Polytechnique Federale de Lausanne (EPFL), Switzerland","institution_ids":["https://openalex.org/I5124864"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004075942","display_name":"Rolf Zeller","orcid":"https://orcid.org/0000-0002-3186-7403"},"institutions":[{"id":"https://openalex.org/I1850255","display_name":"University of Basel","ror":"https://ror.org/02s6k3f65","country_code":"CH","type":"education","lineage":["https://openalex.org/I1850255"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Rolf Zeller","raw_affiliation_strings":["Developmental Genetics, Department of Biomedicine, University of Basel, Switzerland"],"affiliations":[{"raw_affiliation_string":"Developmental Genetics, Department of Biomedicine, University of Basel, Switzerland","institution_ids":["https://openalex.org/I1850255"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5108241811"],"corresponding_institution_ids":["https://openalex.org/I1850255"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":2.8868,"has_fulltext":false,"cited_by_count":15,"citation_normalized_percentile":{"value":0.91296239,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":null,"issue":null,"first_page":"575","last_page":"576"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":0.9932000041007996,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10505","display_name":"Pluripotent Stem Cells Research","score":0.9904000163078308,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11677","display_name":"Congenital heart defects research","score":0.963699996471405,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/morphogen","display_name":"Morphogen","score":0.8603224754333496},{"id":"https://openalex.org/keywords/limb-development","display_name":"Limb development","score":0.7299709320068359},{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.6551059484481812},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6107131242752075},{"id":"https://openalex.org/keywords/systems-biology","display_name":"Systems biology","score":0.5582900643348694},{"id":"https://openalex.org/keywords/fibroblast-growth-factor","display_name":"Fibroblast growth factor","score":0.4959450662136078},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.4720127284526825},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3842715620994568},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.34050214290618896},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.21973097324371338},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.18393951654434204},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.16546642780303955},{"id":"https://openalex.org/keywords/receptor","display_name":"Receptor","score":0.07821837067604065}],"concepts":[{"id":"https://openalex.org/C2778386714","wikidata":"https://www.wikidata.org/wiki/Q417084","display_name":"Morphogen","level":3,"score":0.8603224754333496},{"id":"https://openalex.org/C86370654","wikidata":"https://www.wikidata.org/wiki/Q2277862","display_name":"Limb development","level":3,"score":0.7299709320068359},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.6551059484481812},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6107131242752075},{"id":"https://openalex.org/C152662350","wikidata":"https://www.wikidata.org/wiki/Q815297","display_name":"Systems biology","level":2,"score":0.5582900643348694},{"id":"https://openalex.org/C74373430","wikidata":"https://www.wikidata.org/wiki/Q24727126","display_name":"Fibroblast growth factor","level":3,"score":0.4959450662136078},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.4720127284526825},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3842715620994568},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.34050214290618896},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.21973097324371338},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.18393951654434204},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16546642780303955},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.07821837067604065}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-642-12683-3_40","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-12683-3_40","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/15","score":0.4399999976158142,"display_name":"Life in Land"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":1,"referenced_works":["https://openalex.org/W2046688088"],"related_works":["https://openalex.org/W2324583877","https://openalex.org/W2017936411","https://openalex.org/W1772460563","https://openalex.org/W2048800081","https://openalex.org/W1963463566","https://openalex.org/W3011032586","https://openalex.org/W4246928882","https://openalex.org/W2724632460","https://openalex.org/W200033838","https://openalex.org/W2163991937"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}