{"id":"https://openalex.org/W1597410318","doi":"https://doi.org/10.1007/978-3-642-04271-3_81","title":"Analysis of MR Images of Mice in Preclinical Treatment Monitoring of Polycystic Kidney Disease","display_name":"Analysis of MR Images of Mice in Preclinical Treatment Monitoring of Polycystic Kidney Disease","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W1597410318","doi":"https://doi.org/10.1007/978-3-642-04271-3_81","mag":"1597410318","pmid":"https://pubmed.ncbi.nlm.nih.gov/20426169"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-04271-3_81","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-04271-3_81","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012436496","display_name":"Stathis Hadjidemetriou","orcid":"https://orcid.org/0000-0002-3205-5511"},"institutions":[{"id":"https://openalex.org/I2801240073","display_name":"University Medical Center Freiburg","ror":"https://ror.org/03vzbgh69","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Stathis Hadjidemetriou","raw_affiliation_strings":["University Hospital Freiburg, Dept. of Diagnostic Radiology, Medical Physics, Hugstetter Street 55, 79106 Freiburg, Germany. efstathios.hadjidemetriou@uniklinik-freiburg.de","Dept. of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Hugstetter Street 55, 79106, Freiburg, Germany"],"affiliations":[{"raw_affiliation_string":"University Hospital Freiburg, Dept. of Diagnostic Radiology, Medical Physics, Hugstetter Street 55, 79106 Freiburg, Germany. efstathios.hadjidemetriou@uniklinik-freiburg.de","institution_ids":["https://openalex.org/I2801240073"]},{"raw_affiliation_string":"Dept. of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Hugstetter Street 55, 79106, Freiburg, Germany","institution_ids":["https://openalex.org/I2801240073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066482184","display_name":"Wilfried Reichardt","orcid":"https://orcid.org/0000-0002-8888-399X"},"institutions":[{"id":"https://openalex.org/I2801240073","display_name":"University Medical Center Freiburg","ror":"https://ror.org/03vzbgh69","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Wilfried Reichardt","raw_affiliation_strings":["Dept. of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Hugstetter Street 55, 79106, Freiburg, Germany"],"affiliations":[{"raw_affiliation_string":"Dept. of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Hugstetter Street 55, 79106, Freiburg, Germany","institution_ids":["https://openalex.org/I2801240073"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007018487","display_name":"Martin Buechert","orcid":"https://orcid.org/0000-0001-5844-8711"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Martin Buechert","raw_affiliation_strings":["Magnetic Resonance Development and Application Center, Hugstetter Street 55, 79106, Freiburg, Germany"],"affiliations":[{"raw_affiliation_string":"Magnetic Resonance Development and Application Center, Hugstetter Street 55, 79106, Freiburg, Germany","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074730046","display_name":"J\u00fcrgen Hennig","orcid":"https://orcid.org/0000-0002-2273-3497"},"institutions":[{"id":"https://openalex.org/I2801240073","display_name":"University Medical Center Freiburg","ror":"https://ror.org/03vzbgh69","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Juergen Hennig","raw_affiliation_strings":["Dept. of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Hugstetter Street 55, 79106, Freiburg, Germany"],"affiliations":[{"raw_affiliation_string":"Dept. of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Hugstetter Street 55, 79106, Freiburg, Germany","institution_ids":["https://openalex.org/I2801240073"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5051492696","display_name":"Dominik von Elverfeldt","orcid":"https://orcid.org/0000-0002-6219-3528"},"institutions":[{"id":"https://openalex.org/I2801240073","display_name":"University Medical Center Freiburg","ror":"https://ror.org/03vzbgh69","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I2801240073"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dominik von Elverfeldt","raw_affiliation_strings":["Dept. of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Hugstetter Street 55, 79106, Freiburg, Germany"],"affiliations":[{"raw_affiliation_string":"Dept. of Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Hugstetter Street 55, 79106, Freiburg, Germany","institution_ids":["https://openalex.org/I2801240073"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5012436496"],"corresponding_institution_ids":["https://openalex.org/I2801240073"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":3.1321,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.91192711,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":96},"biblio":{"volume":"12","issue":"Pt 2","first_page":"665","last_page":"672"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11412","display_name":"Genetic and Kidney Cyst Diseases","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11412","display_name":"Genetic and Kidney Cyst Diseases","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12140","display_name":"Renal and related cancers","score":0.991599977016449,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12009","display_name":"Hedgehog Signaling Pathway Studies","score":0.9911999702453613,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/segmentation","display_name":"Segmentation","score":0.7336043119430542},{"id":"https://openalex.org/keywords/autosomal-dominant-polycystic-kidney-disease","display_name":"Autosomal dominant polycystic kidney disease","score":0.7070314884185791},{"id":"https://openalex.org/keywords/polycystic-kidney-disease","display_name":"Polycystic kidney disease","score":0.5939648747444153},{"id":"https://openalex.org/keywords/region-of-interest","display_name":"Region of interest","score":0.5868135094642639},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5604596138000488},{"id":"https://openalex.org/keywords/kidney","display_name":"Kidney","score":0.5068839192390442},{"id":"https://openalex.org/keywords/kidney-disease","display_name":"Kidney disease","score":0.44874897599220276},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.4476020038127899},{"id":"https://openalex.org/keywords/image-segmentation","display_name":"Image segmentation","score":0.4370349645614624},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.40474843978881836},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.35598456859588623},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.18953409790992737}],"concepts":[{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.7336043119430542},{"id":"https://openalex.org/C2776266639","wikidata":"https://www.wikidata.org/wiki/Q2732398","display_name":"Autosomal dominant polycystic kidney disease","level":3,"score":0.7070314884185791},{"id":"https://openalex.org/C2780145431","wikidata":"https://www.wikidata.org/wiki/Q15443105","display_name":"Polycystic kidney disease","level":3,"score":0.5939648747444153},{"id":"https://openalex.org/C19609008","wikidata":"https://www.wikidata.org/wiki/Q2138203","display_name":"Region of interest","level":2,"score":0.5868135094642639},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5604596138000488},{"id":"https://openalex.org/C2780091579","wikidata":"https://www.wikidata.org/wiki/Q9377","display_name":"Kidney","level":2,"score":0.5068839192390442},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.44874897599220276},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4476020038127899},{"id":"https://openalex.org/C124504099","wikidata":"https://www.wikidata.org/wiki/Q56933","display_name":"Image segmentation","level":3,"score":0.4370349645614624},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.40474843978881836},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.35598456859588623},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.18953409790992737}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D004353","descriptor_name":"Drug Evaluation, Preclinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004353","descriptor_name":"Drug Evaluation, Preclinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004353","descriptor_name":"Drug Evaluation, Preclinical","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007090","descriptor_name":"Image Interpretation, Computer-Assisted","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D007690","descriptor_name":"Polycystic Kidney Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D007690","descriptor_name":"Polycystic Kidney Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D007690","descriptor_name":"Polycystic Kidney Diseases","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":false},{"descriptor_ui":"D007690","descriptor_name":"Polycystic Kidney Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007690","descriptor_name":"Polycystic Kidney Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D007690","descriptor_name":"Polycystic Kidney Diseases","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D009025","descriptor_name":"Morpholines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D009025","descriptor_name":"Morpholines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D009025","descriptor_name":"Morpholines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012680","descriptor_name":"Sensitivity and Specificity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013141","descriptor_name":"Spiro Compounds","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D013141","descriptor_name":"Spiro Compounds","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D013141","descriptor_name":"Spiro Compounds","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015203","descriptor_name":"Reproducibility of Results","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-3-642-04271-3_81","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-04271-3_81","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},{"id":"pmid:20426169","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20426169","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8700000047683716,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":14,"referenced_works":["https://openalex.org/W1584247442","https://openalex.org/W1965799410","https://openalex.org/W1977814442","https://openalex.org/W2059784307","https://openalex.org/W2069445413","https://openalex.org/W2098979973","https://openalex.org/W2102702706","https://openalex.org/W2119300483","https://openalex.org/W2120016591","https://openalex.org/W2131191043","https://openalex.org/W2141270723","https://openalex.org/W2146324437","https://openalex.org/W2169527406","https://openalex.org/W2221432021"],"related_works":["https://openalex.org/W2361280987","https://openalex.org/W2012460677","https://openalex.org/W3012135765","https://openalex.org/W2055891993","https://openalex.org/W4213045027","https://openalex.org/W2003260510","https://openalex.org/W3039485340","https://openalex.org/W2318983696","https://openalex.org/W134421892","https://openalex.org/W2336065282"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}