{"id":"https://openalex.org/W1494385052","doi":"https://doi.org/10.1007/978-3-642-02504-4_5","title":"Building Maps of Drugs Mode-of-Action from Gene Expression Data","display_name":"Building Maps of Drugs Mode-of-Action from Gene Expression Data","publication_year":2009,"publication_date":"2009-01-01","ids":{"openalex":"https://openalex.org/W1494385052","doi":"https://doi.org/10.1007/978-3-642-02504-4_5","mag":"1494385052"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-642-02504-4_5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-02504-4_5","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084431909","display_name":"Francesco Iorio","orcid":"https://orcid.org/0000-0001-7063-8913"},"institutions":[{"id":"https://openalex.org/I131729948","display_name":"University of Salerno","ror":"https://ror.org/0192m2k53","country_code":"IT","type":"education","lineage":["https://openalex.org/I131729948"]},{"id":"https://openalex.org/I4210152213","display_name":"Telethon Institute Of Genetics And Medicine","ror":"https://ror.org/04xfdsg27","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210152213","https://openalex.org/I4210154366"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesco Iorio","raw_affiliation_strings":["Neural and Robotic Networks Lab (NeuRoNe Lab), Dept. of Mathematics and Computer Science, University of Salerno, Via Ponte don Melillo, Fisciano, (SA), Italy","Systems and Synthetic Biology Lab, TeleThon Institute of Genetics and Medicine (TIGEM), Via Pietro Castellino, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neural and Robotic Networks Lab (NeuRoNe Lab), Dept. of Mathematics and Computer Science, University of Salerno, Via Ponte don Melillo, Fisciano, (SA), Italy","institution_ids":["https://openalex.org/I131729948"]},{"raw_affiliation_string":"Systems and Synthetic Biology Lab, TeleThon Institute of Genetics and Medicine (TIGEM), Via Pietro Castellino, Naples, Italy","institution_ids":["https://openalex.org/I4210152213"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030668200","display_name":"Roberto Tagliaferri","orcid":"https://orcid.org/0000-0001-8134-9025"},"institutions":[{"id":"https://openalex.org/I131729948","display_name":"University of Salerno","ror":"https://ror.org/0192m2k53","country_code":"IT","type":"education","lineage":["https://openalex.org/I131729948"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Roberto Tagliaferri","raw_affiliation_strings":["DMI, Dipartimento di Matematica ed Informatica, Universit\u00e0 di Salerno, Via Ponte don Melillo, 84084, Fisciano (Sa), Italy","Neural and Robotic Networks Lab (NeuRoNe Lab), Dept. of Mathematics and Computer Science, University of Salerno, Via Ponte don Melillo, Fisciano, (SA), Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"DMI, Dipartimento di Matematica ed Informatica, Universit\u00e0 di Salerno, Via Ponte don Melillo, 84084, Fisciano (Sa), Italy","institution_ids":["https://openalex.org/I131729948"]},{"raw_affiliation_string":"Neural and Robotic Networks Lab (NeuRoNe Lab), Dept. of Mathematics and Computer Science, University of Salerno, Via Ponte don Melillo, Fisciano, (SA), Italy","institution_ids":["https://openalex.org/I131729948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5001896455","display_name":"Diego di Bernardo","orcid":"https://orcid.org/0000-0002-1911-7407"},"institutions":[{"id":"https://openalex.org/I4210152213","display_name":"Telethon Institute Of Genetics And Medicine","ror":"https://ror.org/04xfdsg27","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210152213","https://openalex.org/I4210154366"]},{"id":"https://openalex.org/I71267560","display_name":"University of Naples Federico II","ror":"https://ror.org/05290cv24","country_code":"IT","type":"education","lineage":["https://openalex.org/I71267560"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Diego di Bernardo","raw_affiliation_strings":["Dept. of Computer Science and Systems, University Federico II\u00d3 of Naples, P.le Tecchio, Naples, Italy","Systems and Synthetic Biology Lab, TeleThon Institute of Genetics and Medicine (TIGEM), Via Pietro Castellino, Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Computer Science and Systems, University Federico II\u00d3 of Naples, P.le Tecchio, Naples, Italy","institution_ids":["https://openalex.org/I71267560"]},{"raw_affiliation_string":"Systems and Synthetic Biology Lab, TeleThon Institute of Genetics and Medicine (TIGEM), Via Pietro Castellino, Naples, Italy","institution_ids":["https://openalex.org/I4210152213"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.10171327,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"56","last_page":"65"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.998199999332428,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9979000091552734,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9973999857902527,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7602081298828125},{"id":"https://openalex.org/keywords/normalization","display_name":"Normalization (sociology)","score":0.6802466511726379},{"id":"https://openalex.org/keywords/embedding","display_name":"Embedding","score":0.5981031656265259},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.5959491729736328},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.5908617377281189},{"id":"https://openalex.org/keywords/statistic","display_name":"Statistic","score":0.560357928276062},{"id":"https://openalex.org/keywords/visualization","display_name":"Visualization","score":0.5101706981658936},{"id":"https://openalex.org/keywords/euclidean-distance","display_name":"Euclidean distance","score":0.451199471950531},{"id":"https://openalex.org/keywords/data-set","display_name":"Data set","score":0.44924280047416687},{"id":"https://openalex.org/keywords/euclidean-space","display_name":"Euclidean space","score":0.42988812923431396},{"id":"https://openalex.org/keywords/expression","display_name":"Expression (computer science)","score":0.41613149642944336},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2789907455444336},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.12898263335227966},{"id":"https://openalex.org/keywords/statistics","display_name":"Statistics","score":0.07814663648605347}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7602081298828125},{"id":"https://openalex.org/C136886441","wikidata":"https://www.wikidata.org/wiki/Q926129","display_name":"Normalization (sociology)","level":2,"score":0.6802466511726379},{"id":"https://openalex.org/C41608201","wikidata":"https://www.wikidata.org/wiki/Q980509","display_name":"Embedding","level":2,"score":0.5981031656265259},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.5959491729736328},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.5908617377281189},{"id":"https://openalex.org/C89128539","wikidata":"https://www.wikidata.org/wiki/Q1949963","display_name":"Statistic","level":2,"score":0.560357928276062},{"id":"https://openalex.org/C36464697","wikidata":"https://www.wikidata.org/wiki/Q451553","display_name":"Visualization","level":2,"score":0.5101706981658936},{"id":"https://openalex.org/C120174047","wikidata":"https://www.wikidata.org/wiki/Q847073","display_name":"Euclidean distance","level":2,"score":0.451199471950531},{"id":"https://openalex.org/C58489278","wikidata":"https://www.wikidata.org/wiki/Q1172284","display_name":"Data set","level":2,"score":0.44924280047416687},{"id":"https://openalex.org/C186450821","wikidata":"https://www.wikidata.org/wiki/Q17295","display_name":"Euclidean space","level":2,"score":0.42988812923431396},{"id":"https://openalex.org/C90559484","wikidata":"https://www.wikidata.org/wiki/Q778379","display_name":"Expression (computer science)","level":2,"score":0.41613149642944336},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2789907455444336},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.12898263335227966},{"id":"https://openalex.org/C105795698","wikidata":"https://www.wikidata.org/wiki/Q12483","display_name":"Statistics","level":1,"score":0.07814663648605347},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C202444582","wikidata":"https://www.wikidata.org/wiki/Q837863","display_name":"Pure mathematics","level":1,"score":0.0},{"id":"https://openalex.org/C19165224","wikidata":"https://www.wikidata.org/wiki/Q23404","display_name":"Anthropology","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-642-02504-4_5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-642-02504-4_5","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.47999998927116394,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":6,"referenced_works":["https://openalex.org/W2007292697","https://openalex.org/W2091879895","https://openalex.org/W2118208601","https://openalex.org/W2121604817","https://openalex.org/W2130410032","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2953716828","https://openalex.org/W2904857019","https://openalex.org/W2944728705","https://openalex.org/W3011538607","https://openalex.org/W2904022177","https://openalex.org/W2591697403","https://openalex.org/W4321441197","https://openalex.org/W2359348847","https://openalex.org/W2105228010","https://openalex.org/W2749646986"],"abstract_inverted_index":null,"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}