{"id":"https://openalex.org/W1571891226","doi":"https://doi.org/10.1007/978-3-540-78757-0_3","title":"Generating Linkage Disequilibrium Patterns in Data Simulations Using genomeSIMLA","display_name":"Generating Linkage Disequilibrium Patterns in Data Simulations Using genomeSIMLA","publication_year":2008,"publication_date":"2008-04-02","ids":{"openalex":"https://openalex.org/W1571891226","doi":"https://doi.org/10.1007/978-3-540-78757-0_3","mag":"1571891226"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-540-78757-0_3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-540-78757-0_3","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004289607","display_name":"Todd L. Edwards","orcid":"https://orcid.org/0000-0003-4318-6119"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4210105714","display_name":"Center for Human Genetics","ror":"https://ror.org/01gcrbc43","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210105714"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Todd L. Edwards","raw_affiliation_strings":["Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA","Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN"],"affiliations":[{"raw_affiliation_string":"Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4210105714"]},{"raw_affiliation_string":"Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN","institution_ids":["https://openalex.org/I4210105714","https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066140517","display_name":"William S. Bush","orcid":"https://orcid.org/0000-0002-9729-6519"},"institutions":[{"id":"https://openalex.org/I4210105714","display_name":"Center for Human Genetics","ror":"https://ror.org/01gcrbc43","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210105714"]},{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William S. Bush","raw_affiliation_strings":["Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA","Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN"],"affiliations":[{"raw_affiliation_string":"Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4210105714"]},{"raw_affiliation_string":"Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN","institution_ids":["https://openalex.org/I4210105714","https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068228499","display_name":"Stephen Turner","orcid":"https://orcid.org/0000-0001-9140-9028"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4210105714","display_name":"Center for Human Genetics","ror":"https://ror.org/01gcrbc43","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210105714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen D. Turner","raw_affiliation_strings":["Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA","Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN"],"affiliations":[{"raw_affiliation_string":"Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4210105714"]},{"raw_affiliation_string":"Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN","institution_ids":["https://openalex.org/I4210105714","https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052578174","display_name":"Scott Dudek","orcid":"https://orcid.org/0000-0003-2904-3824"},"institutions":[{"id":"https://openalex.org/I4210105714","display_name":"Center for Human Genetics","ror":"https://ror.org/01gcrbc43","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210105714"]},{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott M. Dudek","raw_affiliation_strings":["Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA","Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN"],"affiliations":[{"raw_affiliation_string":"Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4210105714"]},{"raw_affiliation_string":"Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN","institution_ids":["https://openalex.org/I4210105714","https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037933356","display_name":"Eric S. Torstenson","orcid":"https://orcid.org/0000-0002-8434-7647"},"institutions":[{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]},{"id":"https://openalex.org/I4210105714","display_name":"Center for Human Genetics","ror":"https://ror.org/01gcrbc43","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210105714"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eric S. Torstenson","raw_affiliation_strings":["Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA","Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN"],"affiliations":[{"raw_affiliation_string":"Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4210105714"]},{"raw_affiliation_string":"Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN","institution_ids":["https://openalex.org/I4210105714","https://openalex.org/I200719446"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063778803","display_name":"Mike Schmidt","orcid":"https://orcid.org/0000-0003-4721-1457"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mike Schmidt","raw_affiliation_strings":["Center for Statistical Genetics and Genetic Epidemiology, Miami Institute for Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA","Center for Statistical Genetics and Genetic Epidemiology, Miami Institute for Human Genetics, University of Miami Miller School of Medicine, Miami, FL"],"affiliations":[{"raw_affiliation_string":"Center for Statistical Genetics and Genetic Epidemiology, Miami Institute for Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Center for Statistical Genetics and Genetic Epidemiology, Miami Institute for Human Genetics, University of Miami Miller School of Medicine, Miami, FL","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083429290","display_name":"Eden R. Martin","orcid":"https://orcid.org/0000-0002-4035-9152"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eden Martin","raw_affiliation_strings":["Center for Statistical Genetics and Genetic Epidemiology, Miami Institute for Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA","Center for Statistical Genetics and Genetic Epidemiology, Miami Institute for Human Genetics, University of Miami Miller School of Medicine, Miami, FL"],"affiliations":[{"raw_affiliation_string":"Center for Statistical Genetics and Genetic Epidemiology, Miami Institute for Human Genetics, University of Miami Miller School of Medicine, Miami, FL, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Center for Statistical Genetics and Genetic Epidemiology, Miami Institute for Human Genetics, University of Miami Miller School of Medicine, Miami, FL","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081769614","display_name":"Marylyn D. Ritchie","orcid":"https://orcid.org/0000-0002-1208-1720"},"institutions":[{"id":"https://openalex.org/I4210105714","display_name":"Center for Human Genetics","ror":"https://ror.org/01gcrbc43","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210105714"]},{"id":"https://openalex.org/I200719446","display_name":"Vanderbilt University","ror":"https://ror.org/02vm5rt34","country_code":"US","type":"education","lineage":["https://openalex.org/I200719446"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marylyn D. Ritchie","raw_affiliation_strings":["Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA","Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN"],"affiliations":[{"raw_affiliation_string":"Center for Human Genetics Research, Department of Molecular Physiology & Biophysics, Vanderbilt University, Nashville, TN, USA","institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4210105714"]},{"raw_affiliation_string":"Center for Human Genetics Research, Department of Molecular Physiology and Biophysics, Vanderbilt University, Nashville, TN","institution_ids":["https://openalex.org/I4210105714","https://openalex.org/I200719446"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5004289607"],"corresponding_institution_ids":["https://openalex.org/I200719446","https://openalex.org/I4210105714"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":15.1498,"has_fulltext":false,"cited_by_count":38,"citation_normalized_percentile":{"value":0.98379971,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"24","last_page":"35"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.9962999820709229,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.9828000068664551,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/international-hapmap-project","display_name":"International HapMap Project","score":0.7242320775985718},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6583559513092041},{"id":"https://openalex.org/keywords/linkage-disequilibrium","display_name":"Linkage disequilibrium","score":0.6552625298500061},{"id":"https://openalex.org/keywords/initialization","display_name":"Initialization","score":0.5938436985015869},{"id":"https://openalex.org/keywords/linkage","display_name":"Linkage (software)","score":0.5308747291564941},{"id":"https://openalex.org/keywords/population","display_name":"Population","score":0.5048006772994995},{"id":"https://openalex.org/keywords/multivariate-statistics","display_name":"Multivariate statistics","score":0.5021545886993408},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.48796480894088745},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.33935558795928955},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.13191324472427368},{"id":"https://openalex.org/keywords/human-genome","display_name":"Human genome","score":0.12291502952575684},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.11535495519638062},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.07059547305107117}],"concepts":[{"id":"https://openalex.org/C177580304","wikidata":"https://www.wikidata.org/wiki/Q1147298","display_name":"International HapMap Project","level":5,"score":0.7242320775985718},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6583559513092041},{"id":"https://openalex.org/C35605836","wikidata":"https://www.wikidata.org/wiki/Q2064311","display_name":"Linkage disequilibrium","level":5,"score":0.6552625298500061},{"id":"https://openalex.org/C114466953","wikidata":"https://www.wikidata.org/wiki/Q6034165","display_name":"Initialization","level":2,"score":0.5938436985015869},{"id":"https://openalex.org/C31266012","wikidata":"https://www.wikidata.org/wiki/Q6554340","display_name":"Linkage (software)","level":3,"score":0.5308747291564941},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.5048006772994995},{"id":"https://openalex.org/C161584116","wikidata":"https://www.wikidata.org/wiki/Q1952580","display_name":"Multivariate statistics","level":2,"score":0.5021545886993408},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.48796480894088745},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.33935558795928955},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13191324472427368},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.12291502952575684},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.11535495519638062},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07059547305107117},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C197754878","wikidata":"https://www.wikidata.org/wiki/Q80711","display_name":"Haplotype","level":4,"score":0.0},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.0},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-540-78757-0_3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-540-78757-0_3","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1492992226","https://openalex.org/W1548995919","https://openalex.org/W1891283710","https://openalex.org/W1944558458","https://openalex.org/W1967668456","https://openalex.org/W1980175560","https://openalex.org/W1994050986","https://openalex.org/W1994664175","https://openalex.org/W2006423274","https://openalex.org/W2018823764","https://openalex.org/W2023615944","https://openalex.org/W2031082289","https://openalex.org/W2040709122","https://openalex.org/W2048755332","https://openalex.org/W2058401000","https://openalex.org/W2082122713","https://openalex.org/W2104690544","https://openalex.org/W2110830484","https://openalex.org/W2114123573","https://openalex.org/W2130539871","https://openalex.org/W2134783591","https://openalex.org/W2151773637","https://openalex.org/W2160160618","https://openalex.org/W2161102342","https://openalex.org/W2172260290","https://openalex.org/W4210633230"],"related_works":["https://openalex.org/W2166135130","https://openalex.org/W2171631495","https://openalex.org/W2038652894","https://openalex.org/W1968004796","https://openalex.org/W2158822573","https://openalex.org/W1969997927","https://openalex.org/W2045093806","https://openalex.org/W2391022532","https://openalex.org/W2063478222","https://openalex.org/W2056799531"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":7},{"year":2012,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
