{"id":"https://openalex.org/W1628492644","doi":"https://doi.org/10.1007/978-3-540-73060-6_4","title":"A Context-Specific Network of Protein-DNA and Protein-Protein Interactions Reveals New Regulatory Motifs in Human B Cells","display_name":"A Context-Specific Network of Protein-DNA and Protein-Protein Interactions Reveals New Regulatory Motifs in Human B Cells","publication_year":2007,"publication_date":"2007-09-18","ids":{"openalex":"https://openalex.org/W1628492644","doi":"https://doi.org/10.1007/978-3-540-73060-6_4","mag":"1628492644"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-540-73060-6_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-540-73060-6_4","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5104109891","display_name":"C\u00e9line Lef\u00e8bvre","orcid":null},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Celine Lefebvre","raw_affiliation_strings":["Center for Computational Biology and Bioinformatics, Columbia University, 1130 St Nicholas Avenue, 9th Floor, New York NY 10032,","Center for Computational Biology and Bioinformatics, Columbia University, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Biology and Bioinformatics, Columbia University, 1130 St Nicholas Avenue, 9th Floor, New York NY 10032,","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Center for Computational Biology and Bioinformatics, Columbia University, New York, NY","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087635680","display_name":"Wei Keat Lim","orcid":"https://orcid.org/0000-0002-6226-2570"},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wei Keat Lim","raw_affiliation_strings":["Center for Computational Biology and Bioinformatics, Columbia University, 1130 St Nicholas Avenue, 9th Floor, New York NY 10032,","Center for Computational Biology and Bioinformatics, Columbia University, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Biology and Bioinformatics, Columbia University, 1130 St Nicholas Avenue, 9th Floor, New York NY 10032,","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Center for Computational Biology and Bioinformatics, Columbia University, New York, NY","institution_ids":["https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071634974","display_name":"Katia Basso","orcid":"https://orcid.org/0000-0002-9316-6039"},"institutions":[{"id":"https://openalex.org/I4210145812","display_name":"Cancer Genetics (United States)","ror":"https://ror.org/05feyya22","country_code":"US","type":"company","lineage":["https://openalex.org/I4210145812"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Katia Basso","raw_affiliation_strings":["Institute of Cancer Genetics, Columbia University, 1130 St Nicholas Avenue, New York NY 10032,","Institute of Cancer Genetics, Columbia University, New York, NY#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cancer Genetics, Columbia University, 1130 St Nicholas Avenue, New York NY 10032,","institution_ids":["https://openalex.org/I4210145812"]},{"raw_affiliation_string":"Institute of Cancer Genetics, Columbia University, New York, NY#TAB#","institution_ids":["https://openalex.org/I4210145812","https://openalex.org/I78577930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016969000","display_name":"Riccardo Dalla Favera","orcid":null},"institutions":[{"id":"https://openalex.org/I4210145812","display_name":"Cancer Genetics (United States)","ror":"https://ror.org/05feyya22","country_code":"US","type":"company","lineage":["https://openalex.org/I4210145812"]},{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Riccardo Dalla Favera","raw_affiliation_strings":["Institute of Cancer Genetics, Columbia University, 1130 St Nicholas Avenue, New York NY 10032,","Institute of Cancer Genetics, Columbia University, New York, NY#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Cancer Genetics, Columbia University, 1130 St Nicholas Avenue, New York NY 10032,","institution_ids":["https://openalex.org/I4210145812"]},{"raw_affiliation_string":"Institute of Cancer Genetics, Columbia University, New York, NY#TAB#","institution_ids":["https://openalex.org/I4210145812","https://openalex.org/I78577930"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5046245448","display_name":"Andrea Califano","orcid":"https://orcid.org/0000-0003-4742-3679"},"institutions":[{"id":"https://openalex.org/I78577930","display_name":"Columbia University","ror":"https://ror.org/00hj8s172","country_code":"US","type":"education","lineage":["https://openalex.org/I78577930"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Andrea Califano","raw_affiliation_strings":["Center for Computational Biology and Bioinformatics, Columbia University, 1130 St Nicholas Avenue, 9th Floor, New York NY 10032,","Center for Computational Biology and Bioinformatics, Columbia University, New York, NY"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Computational Biology and Bioinformatics, Columbia University, 1130 St Nicholas Avenue, 9th Floor, New York NY 10032,","institution_ids":["https://openalex.org/I78577930"]},{"raw_affiliation_string":"Center for Computational Biology and Bioinformatics, Columbia University, New York, NY","institution_ids":["https://openalex.org/I78577930"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":3.2883,"has_fulltext":false,"cited_by_count":23,"citation_normalized_percentile":{"value":0.92000344,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"42","last_page":"56"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9983999729156494,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.9983000159263611,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.6237258911132812},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.5963204503059387},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.5433406233787537},{"id":"https://openalex.org/keywords/transcription-factor","display_name":"Transcription factor","score":0.5232590436935425},{"id":"https://openalex.org/keywords/interaction-network","display_name":"Interaction network","score":0.5076748132705688},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.48385679721832275},{"id":"https://openalex.org/keywords/gene-regulatory-network","display_name":"Gene regulatory network","score":0.463625431060791},{"id":"https://openalex.org/keywords/dna","display_name":"DNA","score":0.43278759717941284},{"id":"https://openalex.org/keywords/transcription","display_name":"Transcription (linguistics)","score":0.42799851298332214},{"id":"https://openalex.org/keywords/protein\u2013protein-interaction","display_name":"Protein\u2013protein interaction","score":0.4199789762496948},{"id":"https://openalex.org/keywords/gene-expression","display_name":"Gene expression","score":0.17664608359336853}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.6237258911132812},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5963204503059387},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.5433406233787537},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5232590436935425},{"id":"https://openalex.org/C55105296","wikidata":"https://www.wikidata.org/wiki/Q841382","display_name":"Interaction network","level":3,"score":0.5076748132705688},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.48385679721832275},{"id":"https://openalex.org/C67339327","wikidata":"https://www.wikidata.org/wiki/Q1502576","display_name":"Gene regulatory network","level":4,"score":0.463625431060791},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.43278759717941284},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.42799851298332214},{"id":"https://openalex.org/C11804247","wikidata":"https://www.wikidata.org/wiki/Q896177","display_name":"Protein\u2013protein interaction","level":2,"score":0.4199789762496948},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.17664608359336853},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-540-73060-6_4","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-540-73060-6_4","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1588911128","https://openalex.org/W1872324379","https://openalex.org/W1988496202","https://openalex.org/W1992922335","https://openalex.org/W1994803330","https://openalex.org/W2011986160","https://openalex.org/W2098045561","https://openalex.org/W2101181377","https://openalex.org/W2103017472","https://openalex.org/W2120743639","https://openalex.org/W2121963546","https://openalex.org/W2123280311","https://openalex.org/W2132582966","https://openalex.org/W2134672568","https://openalex.org/W2137335580","https://openalex.org/W2137464714","https://openalex.org/W2137881949","https://openalex.org/W2149310258","https://openalex.org/W2150392051","https://openalex.org/W2153577994","https://openalex.org/W2155723007","https://openalex.org/W2161409973","https://openalex.org/W2163296115","https://openalex.org/W2166898290","https://openalex.org/W3099289621","https://openalex.org/W4255855797"],"related_works":["https://openalex.org/W4229728790","https://openalex.org/W2800059693","https://openalex.org/W2066232588","https://openalex.org/W4377086792","https://openalex.org/W2767490506","https://openalex.org/W1987705964","https://openalex.org/W1841073402","https://openalex.org/W2106286319","https://openalex.org/W2069244164","https://openalex.org/W3087302704"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":1}],"updated_date":"2026-06-11T09:08:48.828518","created_date":"2025-10-10T00:00:00"}