{"id":"https://openalex.org/W1578770889","doi":"https://doi.org/10.1007/978-3-540-30217-9_52","title":"Designing Multiple-Use Primer Set for Multiplex PCR by Using Compact GAs","display_name":"Designing Multiple-Use Primer Set for Multiplex PCR by Using Compact GAs","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W1578770889","doi":"https://doi.org/10.1007/978-3-540-30217-9_52","mag":"1578770889"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-540-30217-9_52","is_oa":true,"landing_page_url":"https://doi.org/10.1007/978-3-540-30217-9_52","pdf_url":"https://link.springer.com/content/pdf/10.1007/978-3-540-30217-9_52.pdf","source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"conference-paper","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://link.springer.com/content/pdf/10.1007/978-3-540-30217-9_52.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083657574","display_name":"Yucheng Huang","orcid":"https://orcid.org/0000-0002-2367-6199"},"institutions":[{"id":"https://openalex.org/I16733864","display_name":"National Taiwan University","ror":"https://ror.org/05bqach95","country_code":"TW","type":"education","lineage":["https://openalex.org/I16733864"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yu-Cheng Huang","raw_affiliation_strings":["Dept. of Computer Science and Information Engineering, National Taiwan University, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Computer Science and Information Engineering, National Taiwan University, Taiwan","institution_ids":["https://openalex.org/I16733864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067041449","display_name":"Han\u2010Yu Chuang","orcid":null},"institutions":[{"id":"https://openalex.org/I16733864","display_name":"National Taiwan University","ror":"https://ror.org/05bqach95","country_code":"TW","type":"education","lineage":["https://openalex.org/I16733864"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Han-Yu Chuang","raw_affiliation_strings":["Dept. of Computer Science and Information Engineering, National Taiwan University, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Computer Science and Information Engineering, National Taiwan University, Taiwan","institution_ids":["https://openalex.org/I16733864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000235008","display_name":"Huai\u2010Kuang Tsai","orcid":"https://orcid.org/0000-0002-4200-8137"},"institutions":[{"id":"https://openalex.org/I16733864","display_name":"National Taiwan University","ror":"https://ror.org/05bqach95","country_code":"TW","type":"education","lineage":["https://openalex.org/I16733864"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Huai-Kuang Tsai","raw_affiliation_strings":["Dept. of Computer Science and Information Engineering, National Taiwan University, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Computer Science and Information Engineering, National Taiwan University, Taiwan","institution_ids":["https://openalex.org/I16733864"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061318739","display_name":"Chun-Fan Chang","orcid":null},"institutions":[{"id":"https://openalex.org/I205612303","display_name":"Chinese Culture University","ror":"https://ror.org/04shepe48","country_code":"TW","type":"education","lineage":["https://openalex.org/I205612303"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Chun-Fan Chang","raw_affiliation_strings":["Chinese Culture University, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Chinese Culture University, Taiwan","institution_ids":["https://openalex.org/I205612303"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102154466","display_name":"Cheng\u2010Yan Kao","orcid":null},"institutions":[{"id":"https://openalex.org/I16733864","display_name":"National Taiwan University","ror":"https://ror.org/05bqach95","country_code":"TW","type":"education","lineage":["https://openalex.org/I16733864"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Cheng-Yan Kao","raw_affiliation_strings":["Dept. of Computer Science and Information Engineering, National Taiwan University, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dept. of Computer Science and Information Engineering, National Taiwan University, Taiwan","institution_ids":["https://openalex.org/I16733864"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":0.0,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.09028815,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"511","last_page":"521"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11970","display_name":"Molecular Biology Techniques and Applications","score":0.9987999796867371,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10848","display_name":"Advanced Multi-Objective Optimization Algorithms","score":0.9908999800682068,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9886999726295471,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/primer","display_name":"Primer (cosmetics)","score":0.7670822143554688},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6884326338768005},{"id":"https://openalex.org/keywords/heuristic","display_name":"Heuristic","score":0.6483609080314636},{"id":"https://openalex.org/keywords/multiplex-polymerase-chain-reaction","display_name":"Multiplex polymerase chain reaction","score":0.6428278088569641},{"id":"https://openalex.org/keywords/computation","display_name":"Computation","score":0.6149577498435974},{"id":"https://openalex.org/keywords/multiplex","display_name":"Multiplex","score":0.6068497896194458},{"id":"https://openalex.org/keywords/set","display_name":"Set (abstract data type)","score":0.594204306602478},{"id":"https://openalex.org/keywords/genetic-algorithm","display_name":"Genetic algorithm","score":0.4786611497402191},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.4228246212005615},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.4127289354801178},{"id":"https://openalex.org/keywords/polymerase-chain-reaction","display_name":"Polymerase chain reaction","score":0.359016478061676},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.18052303791046143},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.17984822392463684},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.11257156729698181},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.10773018002510071},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.08113223314285278}],"concepts":[{"id":"https://openalex.org/C2777563447","wikidata":"https://www.wikidata.org/wiki/Q7243397","display_name":"Primer (cosmetics)","level":2,"score":0.7670822143554688},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6884326338768005},{"id":"https://openalex.org/C173801870","wikidata":"https://www.wikidata.org/wiki/Q201413","display_name":"Heuristic","level":2,"score":0.6483609080314636},{"id":"https://openalex.org/C90583042","wikidata":"https://www.wikidata.org/wiki/Q1952456","display_name":"Multiplex polymerase chain reaction","level":4,"score":0.6428278088569641},{"id":"https://openalex.org/C45374587","wikidata":"https://www.wikidata.org/wiki/Q12525525","display_name":"Computation","level":2,"score":0.6149577498435974},{"id":"https://openalex.org/C2781188995","wikidata":"https://www.wikidata.org/wiki/Q6934982","display_name":"Multiplex","level":2,"score":0.6068497896194458},{"id":"https://openalex.org/C177264268","wikidata":"https://www.wikidata.org/wiki/Q1514741","display_name":"Set (abstract data type)","level":2,"score":0.594204306602478},{"id":"https://openalex.org/C8880873","wikidata":"https://www.wikidata.org/wiki/Q187787","display_name":"Genetic algorithm","level":2,"score":0.4786611497402191},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4228246212005615},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.4127289354801178},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.359016478061676},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.18052303791046143},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17984822392463684},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.11257156729698181},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10773018002510071},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.08113223314285278},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-540-30217-9_52","is_oa":true,"landing_page_url":"https://doi.org/10.1007/978-3-540-30217-9_52","pdf_url":"https://link.springer.com/content/pdf/10.1007/978-3-540-30217-9_52.pdf","source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":{"id":"doi:10.1007/978-3-540-30217-9_52","is_oa":true,"landing_page_url":"https://doi.org/10.1007/978-3-540-30217-9_52","pdf_url":"https://link.springer.com/content/pdf/10.1007/978-3-540-30217-9_52.pdf","source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1578770889.pdf","grobid_xml":"https://content.openalex.org/works/W1578770889.grobid-xml"},"referenced_works_count":25,"referenced_works":["https://openalex.org/W203272431","https://openalex.org/W1521380130","https://openalex.org/W1560337332","https://openalex.org/W1750082253","https://openalex.org/W1963953102","https://openalex.org/W1974250007","https://openalex.org/W2007287649","https://openalex.org/W2011039300","https://openalex.org/W2011546759","https://openalex.org/W2016207616","https://openalex.org/W2016929496","https://openalex.org/W2020643009","https://openalex.org/W2022637272","https://openalex.org/W2049967755","https://openalex.org/W2070557871","https://openalex.org/W2084507708","https://openalex.org/W2093843227","https://openalex.org/W2099813847","https://openalex.org/W2116661285","https://openalex.org/W2118066113","https://openalex.org/W2142448093","https://openalex.org/W2148379945","https://openalex.org/W2149181019","https://openalex.org/W2169629105","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2375570161","https://openalex.org/W3084381115","https://openalex.org/W2360792334","https://openalex.org/W2133683229","https://openalex.org/W2083048402","https://openalex.org/W1975323116","https://openalex.org/W2066005224","https://openalex.org/W2367685784","https://openalex.org/W1585187208","https://openalex.org/W2113143881"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-08-04T08:18:43.703281","created_date":"2025-10-10T00:00:00"}