{"id":"https://openalex.org/W2607196065","doi":"https://doi.org/10.1007/978-3-319-56970-3_20","title":"The Copy-Number Tree Mixture Deconvolution Problem and Applications to Multi-sample Bulk Sequencing Tumor Data","display_name":"The Copy-Number Tree Mixture Deconvolution Problem and Applications to Multi-sample Bulk Sequencing Tumor Data","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2607196065","doi":"https://doi.org/10.1007/978-3-319-56970-3_20","mag":"2607196065"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-319-56970-3_20","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-56970-3_20","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://ir.cwi.nl/pub/25770/RCMB7937.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015317678","display_name":"Simone Zaccaria","orcid":"https://orcid.org/0000-0002-5265-7392"},"institutions":[{"id":"https://openalex.org/I66752286","display_name":"University of Milano-Bicocca","ror":"https://ror.org/01ynf4891","country_code":"IT","type":"education","lineage":["https://openalex.org/I66752286"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["IT","US"],"is_corresponding":true,"raw_author_name":"Simone Zaccaria","raw_affiliation_strings":["Department of Computer Science, Brown University, Providence, Rhode Island, 02912, USA","Dipartimento di Informatica, Univ. degli Studi di Milano-Bicocca, Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Brown University, Providence, Rhode Island, 02912, USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Dipartimento di Informatica, Univ. degli Studi di Milano-Bicocca, Milan, Italy","institution_ids":["https://openalex.org/I66752286"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089040838","display_name":"Mohammed El-Kebir","orcid":"https://orcid.org/0000-0002-1468-2407"},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mohammed El-Kebir","raw_affiliation_strings":["Department of Computer Science, Brown University, Providence, Rhode Island, 02912, USA","Department of Computer Science, Princeton University, Princeton, New Jersey, 08540, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Brown University, Providence, Rhode Island, 02912, USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Department of Computer Science, Princeton University, Princeton, New Jersey, 08540, USA","institution_ids":["https://openalex.org/I20089843"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029642674","display_name":"Gunnar W. Klau","orcid":"https://orcid.org/0000-0002-6340-0090"},"institutions":[{"id":"https://openalex.org/I1341640284","display_name":"Centrum Wiskunde & Informatica","ror":"https://ror.org/00x7ekv49","country_code":"NL","type":"facility","lineage":["https://openalex.org/I1341640284","https://openalex.org/I2800991832"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]},{"id":"https://openalex.org/I44260953","display_name":"Heinrich Heine University D\u00fcsseldorf","ror":"https://ror.org/024z2rq82","country_code":"DE","type":"education","lineage":["https://openalex.org/I44260953"]}],"countries":["DE","NL","US"],"is_corresponding":false,"raw_author_name":"Gunnar W. Klau","raw_affiliation_strings":["Algorithmic Bioinformatics, Heinrich Heine University, D\u00fcsseldorf, Germany","Department of Computer Science, Brown University, Providence, Rhode Island, 02912, USA","Life Sciences Group, Centrum Wiskunde & Informatica (CWI), Amsterdam, The Netherlands"],"affiliations":[{"raw_affiliation_string":"Algorithmic Bioinformatics, Heinrich Heine University, D\u00fcsseldorf, Germany","institution_ids":["https://openalex.org/I44260953"]},{"raw_affiliation_string":"Department of Computer Science, Brown University, Providence, Rhode Island, 02912, USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Life Sciences Group, Centrum Wiskunde & Informatica (CWI), Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I1341640284"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5025899028","display_name":"Benjamin J. Raphael","orcid":"https://orcid.org/0000-0003-1274-048X"},"institutions":[{"id":"https://openalex.org/I20089843","display_name":"Princeton University","ror":"https://ror.org/00hx57361","country_code":"US","type":"education","lineage":["https://openalex.org/I20089843"]},{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Benjamin J. Raphael","raw_affiliation_strings":["Department of Computer Science, Brown University, Providence, Rhode Island, 02912, USA","Department of Computer Science, Princeton University, Princeton, New Jersey, 08540, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, Brown University, Providence, Rhode Island, 02912, USA","institution_ids":["https://openalex.org/I27804330"]},{"raw_affiliation_string":"Department of Computer Science, Princeton University, Princeton, New Jersey, 08540, USA","institution_ids":["https://openalex.org/I20089843"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5015317678"],"corresponding_institution_ids":["https://openalex.org/I27804330","https://openalex.org/I66752286"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":5.0912,"has_fulltext":true,"cited_by_count":25,"citation_normalized_percentile":{"value":0.95757576,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"318","last_page":"335"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11369","display_name":"Genetic factors in colorectal cancer","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/phylogenetic-tree","display_name":"Phylogenetic tree","score":0.8142558336257935},{"id":"https://openalex.org/keywords/tree","display_name":"Tree (set theory)","score":0.6380493640899658},{"id":"https://openalex.org/keywords/deconvolution","display_name":"Deconvolution","score":0.5837100148200989},{"id":"https://openalex.org/keywords/tree-rearrangement","display_name":"Tree rearrangement","score":0.5244900584220886},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.480146586894989},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.44046926498413086},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.416179895401001},{"id":"https://openalex.org/keywords/algorithm","display_name":"Algorithm","score":0.3843514621257782},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.24298998713493347},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2304299771785736},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.139804869890213},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.11612063646316528}],"concepts":[{"id":"https://openalex.org/C193252679","wikidata":"https://www.wikidata.org/wiki/Q242125","display_name":"Phylogenetic tree","level":3,"score":0.8142558336257935},{"id":"https://openalex.org/C113174947","wikidata":"https://www.wikidata.org/wiki/Q2859736","display_name":"Tree (set theory)","level":2,"score":0.6380493640899658},{"id":"https://openalex.org/C174576160","wikidata":"https://www.wikidata.org/wiki/Q1183700","display_name":"Deconvolution","level":2,"score":0.5837100148200989},{"id":"https://openalex.org/C53208351","wikidata":"https://www.wikidata.org/wiki/Q7837630","display_name":"Tree rearrangement","level":4,"score":0.5244900584220886},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.480146586894989},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.44046926498413086},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.416179895401001},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.3843514621257782},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.24298998713493347},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2304299771785736},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.139804869890213},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.11612063646316528}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/978-3-319-56970-3_20","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-56970-3_20","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},{"id":"pmh:oai:cwi.nl:25770","is_oa":true,"landing_page_url":"https://ir.cwi.nl/pub/25770","pdf_url":"https://ir.cwi.nl/pub/25770/RCMB7937.pdf","source":{"id":"https://openalex.org/S7407055335","display_name":"Centrum Wiskunde & Informatica (CWI), the national research institute for mathematics and computer science in the Netherlands","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"}],"best_oa_location":{"id":"pmh:oai:cwi.nl:25770","is_oa":true,"landing_page_url":"https://ir.cwi.nl/pub/25770","pdf_url":"https://ir.cwi.nl/pub/25770/RCMB7937.pdf","source":{"id":"https://openalex.org/S7407055335","display_name":"Centrum Wiskunde & Informatica (CWI), the national research institute for mathematics and computer science in the Netherlands","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G2847588046","display_name":null,"funder_award_id":"R01HG007069","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G3497591915","display_name":null,"funder_award_id":"(NIH)","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G361500113","display_name":"CAREER:  Algorithms for Next-Generation Genomics","funder_award_id":"1053753","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G6287737109","display_name":null,"funder_award_id":"CCF-1053753","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G6671297155","display_name":null,"funder_award_id":"CAREER","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2607196065.pdf"},"referenced_works_count":34,"referenced_works":["https://openalex.org/W1640140784","https://openalex.org/W1965001144","https://openalex.org/W1967304777","https://openalex.org/W1979693095","https://openalex.org/W2002295829","https://openalex.org/W2006288875","https://openalex.org/W2010873488","https://openalex.org/W2016661249","https://openalex.org/W2048154580","https://openalex.org/W2050146329","https://openalex.org/W2051570610","https://openalex.org/W2088735033","https://openalex.org/W2096746187","https://openalex.org/W2109991075","https://openalex.org/W2111187843","https://openalex.org/W2111874706","https://openalex.org/W2122392334","https://openalex.org/W2127214385","https://openalex.org/W2131416340","https://openalex.org/W2138019532","https://openalex.org/W2150575159","https://openalex.org/W2154598603","https://openalex.org/W2170490448","https://openalex.org/W2233603983","https://openalex.org/W2238824573","https://openalex.org/W2269040222","https://openalex.org/W2339819569","https://openalex.org/W2400394836","https://openalex.org/W2402730620","https://openalex.org/W2416255737","https://openalex.org/W2482614962","https://openalex.org/W2502685008","https://openalex.org/W2515462796","https://openalex.org/W2543676470"],"related_works":["https://openalex.org/W85430217","https://openalex.org/W4205930990","https://openalex.org/W1993799876","https://openalex.org/W2917424786","https://openalex.org/W3088015816","https://openalex.org/W2607237371","https://openalex.org/W3212896338","https://openalex.org/W2785637779","https://openalex.org/W2362218761","https://openalex.org/W2113708670"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":1}],"updated_date":"2026-04-21T08:09:41.155169","created_date":"2025-10-10T00:00:00"}