{"id":"https://openalex.org/W2464694747","doi":"https://doi.org/10.1007/978-3-319-43681-4_9","title":"The Gene Family-Free Median of Three","display_name":"The Gene Family-Free Median of Three","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2464694747","doi":"https://doi.org/10.1007/978-3-319-43681-4_9","mag":"2464694747","pmid":"https://pubmed.ncbi.nlm.nih.gov/28559921"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-319-43681-4_9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-43681-4_9","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"preprint","indexed_in":["arxiv","crossref","datacite","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://almob.biomedcentral.com/track/pdf/10.1186/s13015-017-0106-z","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5055740017","display_name":"Daniel Doerr","orcid":"https://orcid.org/0000-0002-3720-6227"},"institutions":[{"id":"https://openalex.org/I174424907","display_name":"Laboratoire d'Informatique Fondamentale de Lille","ror":"https://ror.org/05rhg0h08","country_code":"FR","type":"facility","lineage":["https://openalex.org/I174424907"]},{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH","FR"],"is_corresponding":false,"raw_author_name":"Daniel Doerr","raw_affiliation_strings":["School of Computer and Communication Sciences, EPFL, 1015, Lausanne, Switzerland","School of Computer and Communication Sciences, EPFL#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer and Communication Sciences, EPFL, 1015, Lausanne, Switzerland","institution_ids":["https://openalex.org/I5124864"]},{"raw_affiliation_string":"School of Computer and Communication Sciences, EPFL#TAB#","institution_ids":["https://openalex.org/I174424907"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025531180","display_name":"Pedro Feij\u00e3o","orcid":null},"institutions":[{"id":"https://openalex.org/I20121455","display_name":"Bielefeld University","ror":"https://ror.org/02hpadn98","country_code":"DE","type":"education","lineage":["https://openalex.org/I20121455"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Pedro Feij\u00e3o","raw_affiliation_strings":["Faculty of Technology, Bielefeld University, 33615, Bielefeld, Germany","[Bielefeld University]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Technology, Bielefeld University, 33615, Bielefeld, Germany","institution_ids":["https://openalex.org/I20121455"]},{"raw_affiliation_string":"[Bielefeld University]","institution_ids":["https://openalex.org/I20121455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083364801","display_name":"Metin Balaban","orcid":"https://orcid.org/0000-0002-6947-5915"},"institutions":[{"id":"https://openalex.org/I174424907","display_name":"Laboratoire d'Informatique Fondamentale de Lille","ror":"https://ror.org/05rhg0h08","country_code":"FR","type":"facility","lineage":["https://openalex.org/I174424907"]},{"id":"https://openalex.org/I5124864","display_name":"\u00c9cole Polytechnique F\u00e9d\u00e9rale de Lausanne","ror":"https://ror.org/02s376052","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I5124864"]}],"countries":["CH","FR"],"is_corresponding":false,"raw_author_name":"Metin Balaban","raw_affiliation_strings":["School of Computer and Communication Sciences, EPFL, 1015, Lausanne, Switzerland","School of Computer and Communication Sciences, EPFL#TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Computer and Communication Sciences, EPFL, 1015, Lausanne, Switzerland","institution_ids":["https://openalex.org/I5124864"]},{"raw_affiliation_string":"School of Computer and Communication Sciences, EPFL#TAB#","institution_ids":["https://openalex.org/I174424907"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5063811688","display_name":"C\u00e9dric Chauve","orcid":"https://orcid.org/0000-0001-9837-1878"},"institutions":[{"id":"https://openalex.org/I18014758","display_name":"Simon Fraser University","ror":"https://ror.org/0213rcc28","country_code":"CA","type":"education","lineage":["https://openalex.org/I18014758"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Cedric Chauve","raw_affiliation_strings":["Department of Mathematics, Simon Fraser University, Burnaby, BC, Canada","[Simon Fraser University]"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Mathematics, Simon Fraser University, Burnaby, BC, Canada","institution_ids":["https://openalex.org/I18014758"]},{"raw_affiliation_string":"[Simon Fraser University]","institution_ids":["https://openalex.org/I18014758"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":{"value":5000,"currency":"EUR","value_usd":5392},"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.04863412,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"12","issue":"1","first_page":"102","last_page":"120"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13664","display_name":"Genome Rearrangement Algorithms","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13664","display_name":"Genome Rearrangement Algorithms","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11269","display_name":"Algorithms and Data Compression","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.7168313264846802},{"id":"https://openalex.org/keywords/breakpoint","display_name":"Breakpoint","score":0.5396753549575806},{"id":"https://openalex.org/keywords/adjacency-list","display_name":"Adjacency list","score":0.5292032957077026},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5201752185821533},{"id":"https://openalex.org/keywords/gene-family","display_name":"Gene family","score":0.4982638359069824},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.48787856101989746},{"id":"https://openalex.org/keywords/similarity","display_name":"Similarity (geometry)","score":0.48477858304977417},{"id":"https://openalex.org/keywords/comparative-genomics","display_name":"Comparative genomics","score":0.47059333324432373},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.4407891631126404},{"id":"https://openalex.org/keywords/graph","display_name":"Graph","score":0.4359130263328552},{"id":"https://openalex.org/keywords/gene-prediction","display_name":"Gene prediction","score":0.42832377552986145},{"id":"https://openalex.org/keywords/sequence","display_name":"Sequence (biology)","score":0.4215218424797058},{"id":"https://openalex.org/keywords/extant-taxon","display_name":"Extant taxon","score":0.41092246770858765},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4078955352306366},{"id":"https://openalex.org/keywords/genomics","display_name":"Genomics","score":0.38808658719062805},{"id":"https://openalex.org/keywords/combinatorics","display_name":"Combinatorics","score":0.3384284973144531},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.30315589904785156},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.24299803376197815},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.1408856213092804},{"id":"https://openalex.org/keywords/evolutionary-biology","display_name":"Evolutionary biology","score":0.1264672875404358}],"concepts":[{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.7168313264846802},{"id":"https://openalex.org/C206936463","wikidata":"https://www.wikidata.org/wiki/Q634179","display_name":"Breakpoint","level":4,"score":0.5396753549575806},{"id":"https://openalex.org/C110484373","wikidata":"https://www.wikidata.org/wiki/Q264398","display_name":"Adjacency list","level":2,"score":0.5292032957077026},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5201752185821533},{"id":"https://openalex.org/C5911399","wikidata":"https://www.wikidata.org/wiki/Q2278983","display_name":"Gene family","level":4,"score":0.4982638359069824},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.48787856101989746},{"id":"https://openalex.org/C103278499","wikidata":"https://www.wikidata.org/wiki/Q254465","display_name":"Similarity (geometry)","level":3,"score":0.48477858304977417},{"id":"https://openalex.org/C105176652","wikidata":"https://www.wikidata.org/wiki/Q1147112","display_name":"Comparative genomics","level":5,"score":0.47059333324432373},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.4407891631126404},{"id":"https://openalex.org/C132525143","wikidata":"https://www.wikidata.org/wiki/Q141488","display_name":"Graph","level":2,"score":0.4359130263328552},{"id":"https://openalex.org/C105565629","wikidata":"https://www.wikidata.org/wiki/Q1248292","display_name":"Gene prediction","level":4,"score":0.42832377552986145},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.4215218424797058},{"id":"https://openalex.org/C178300618","wikidata":"https://www.wikidata.org/wiki/Q1898509","display_name":"Extant taxon","level":2,"score":0.41092246770858765},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4078955352306366},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.38808658719062805},{"id":"https://openalex.org/C114614502","wikidata":"https://www.wikidata.org/wiki/Q76592","display_name":"Combinatorics","level":1,"score":0.3384284973144531},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.30315589904785156},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.24299803376197815},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.1408856213092804},{"id":"https://openalex.org/C78458016","wikidata":"https://www.wikidata.org/wiki/Q840400","display_name":"Evolutionary biology","level":1,"score":0.1264672875404358},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.0},{"id":"https://openalex.org/C138626823","wikidata":"https://www.wikidata.org/wiki/Q916504","display_name":"Chromosomal translocation","level":3,"score":0.0}],"mesh":[],"locations_count":13,"locations":[{"id":"doi:10.1007/978-3-319-43681-4_9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-43681-4_9","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},{"id":"doi:10.1186/s13015-017-0106-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13015-017-0106-z","pdf_url":"https://almob.biomedcentral.com/track/pdf/10.1186/s13015-017-0106-z","source":{"id":"https://openalex.org/S205663195","display_name":"Algorithms for Molecular Biology","issn_l":"1748-7188","issn":["1748-7188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Algorithms for Molecular Biology","raw_type":"journal-article"},{"id":"pmid:28559921","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/28559921","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Algorithms for molecular biology : AMB","raw_type":null},{"id":"pmh:oai:arXiv.org:1606.05910","is_oa":true,"landing_page_url":"http://arxiv.org/abs/1606.05910","pdf_url":"https://arxiv.org/pdf/1606.05910","source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"},{"id":"mag:2464694747","is_oa":true,"landing_page_url":"http://export.arxiv.org/pdf/1606.05910","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"arXiv (Cornell University)","raw_type":null},{"id":"pmh:oai:doaj.org/article:701fbc85be564a298e8c09687275af1f","is_oa":true,"landing_page_url":"https://doaj.org/article/701fbc85be564a298e8c09687275af1f","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Algorithms for Molecular Biology, Vol 12, Iss 1, Pp 1-14 (2017)","raw_type":"article"},{"id":"pmh:oai:europepmc.org:4295286","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/5446766","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:infoscience.epfl.ch:229696","is_oa":true,"landing_page_url":"http://infoscience.epfl.ch/record/229696","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:infoscience.tind.io:225270","is_oa":true,"landing_page_url":"https://infoscience.epfl.ch/handle/20.500.14299/133875","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"conference proceedings"},{"id":"pmh:oai:infoscience.tind.io:229696","is_oa":true,"landing_page_url":"https://infoscience.epfl.ch/handle/20.500.14299/139075","pdf_url":null,"source":{"id":"https://openalex.org/S4306400487","display_name":"Infoscience (Ecole Polytechnique F\u00e9d\u00e9rale de Lausanne)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"research article"},{"id":"doi:10.48550/arxiv.1606.05910","is_oa":true,"landing_page_url":"https://doi.org/10.48550/arxiv.1606.05910","pdf_url":null,"source":{"id":"https://openalex.org/S4306400194","display_name":"arXiv (Cornell University)","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I205783295","host_organization_name":"Cornell University","host_organization_lineage":["https://openalex.org/I205783295"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article"},{"id":"doi:10.6084/m9.figshare.c.3789478","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.c.3789478","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article"},{"id":"doi:10.6084/m9.figshare.c.3789478.v1","is_oa":true,"landing_page_url":"https://doi.org/10.6084/m9.figshare.c.3789478.v1","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":null,"is_accepted":false,"is_published":null,"raw_source_name":null,"raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/s13015-017-0106-z","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13015-017-0106-z","pdf_url":"https://almob.biomedcentral.com/track/pdf/10.1186/s13015-017-0106-z","source":{"id":"https://openalex.org/S205663195","display_name":"Algorithms for Molecular Biology","issn_l":"1748-7188","issn":["1748-7188"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Algorithms for Molecular Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Partnerships for the goals","score":0.49000000953674316,"id":"https://metadata.un.org/sdg/17"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321487","display_name":"Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"},{"id":"https://openalex.org/F4320334593","display_name":"Natural Sciences and Engineering Research Council of Canada","ror":"https://ror.org/01h531d29"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2464694747.pdf","grobid_xml":"https://content.openalex.org/works/W2464694747.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W319819633","https://openalex.org/W1481103812","https://openalex.org/W1517399014","https://openalex.org/W1967621400","https://openalex.org/W1979835060","https://openalex.org/W1980948656","https://openalex.org/W1986644389","https://openalex.org/W1999163215","https://openalex.org/W2004707197","https://openalex.org/W2029036185","https://openalex.org/W2032146159","https://openalex.org/W2038225707","https://openalex.org/W2041386815","https://openalex.org/W2055043387","https://openalex.org/W2100874222","https://openalex.org/W2116245614","https://openalex.org/W2139231345","https://openalex.org/W2386581568","https://openalex.org/W2590560913"],"related_works":["https://openalex.org/W2963443301","https://openalex.org/W1937590909","https://openalex.org/W4226351012","https://openalex.org/W2241525119","https://openalex.org/W1491114444","https://openalex.org/W1492180884","https://openalex.org/W73633159","https://openalex.org/W3012690863","https://openalex.org/W145877605","https://openalex.org/W1973260309","https://openalex.org/W2099956347","https://openalex.org/W1522355229","https://openalex.org/W2188453950","https://openalex.org/W2765896480","https://openalex.org/W1494919299","https://openalex.org/W2079438607","https://openalex.org/W2946809214","https://openalex.org/W1579842940","https://openalex.org/W2166727973","https://openalex.org/W1555746086"],"abstract_inverted_index":{"The":[0,174],"gene":[1,12,20,99,213],"family-free":[2,76,125,226],"framework":[3],"for":[4,11,45,67,114,127,130,142,146,156,181,231,244],"comparative":[5],"genomics":[6],"aims":[7],"at":[8],"providing":[9],"methods":[10,176],"order":[13],"analysis":[14],"that":[15,52,84],"do":[16],"not":[17],"require":[18],"prior":[19],"family":[21,214],"assignment,":[22],"but":[23],"work":[24],"directly":[25],"on":[26,79,189],"a":[27,49,65,69,98,121,165,224],"sequence":[28,92],"similarity":[29,93],"graph.":[30],"We":[31,63,101,118,160,218],"study":[32,102,219],"two":[33],"problems":[34],"related":[35,122],"to":[36,59,163,210,241],"the":[37,46,54,60,86,95,131,149,197,211,220],"breakpoint":[38,57,88],"median":[39,70],"of":[40,48,56,71,97,134,151,186,223],"three":[41,72],"genomes,":[42],"which":[43,169],"asks":[44],"construction":[47],"fourth":[50],"genome":[51],"minimizes":[53],"sum":[55],"distances":[58],"input":[61],"genomes.":[62],"present":[64,139,229],"model":[66,227],"constructing":[68],"genomes":[73,129,182,188],"in":[74,94,172,184],"this":[75,147],"setting,":[77],"based":[78],"maximizing":[80],"an":[81,109,140,238],"objective":[82],"function":[83],"generalizes":[85],"classical":[87],"distance":[89],"by":[90],"integrating":[91],"score":[96],"adjacency.":[100],"its":[103,115,143,232],"computational":[104,221],"complexity":[105,222],"and":[106,138,192,228],"we":[107,236],"describe":[108,164],"integer":[110],"linear":[111],"program":[112],"(ILP)":[113],"exact":[116,152],"solution.":[117,144,233],"further":[119],"discuss":[120],"problem":[123],"called":[124],"adjacencies":[126],"k":[128],"special":[132],"case":[133],"$$k":[135],"\\le":[136],"3$$":[137],"ILP":[141],"However,":[145],"problem,":[148],"computation":[150],"solutions":[153],"remains":[154],"intractable":[155],"sufficiently":[157],"large":[158],"instances.":[159],"then":[161],"proceed":[162],"heuristic":[166],"method,":[167],"FFAdj-AM,":[168,235],"performs":[170,204],"well":[171],"practice.":[173],"developed":[175],"compute":[177],"accurate":[178],"positional":[179,248],"orthologs":[180],"comparable":[183],"size":[185],"bacterial":[187],"simulated":[190],"data":[191,194],"genomic":[193],"acquired":[195],"from":[196],"OMA":[198],"orthology":[199],"database.":[200],"In":[201],"particular,":[202],"FFAdj-AM":[203],"equally":[205],"or":[206],"better":[207],"when":[208],"compared":[209],"well-established":[212],"prediction":[215],"tool":[216],"MultiMSOAR.":[217],"new":[225],"algorithms":[230],"With":[234],"propose":[237],"appealing":[239],"alternative":[240],"established":[242],"tools":[243],"identifying":[245],"higher":[246],"confidence":[247],"orthologs.":[249]},"counts_by_year":[],"updated_date":"2026-06-17T08:01:34.144755","created_date":"2025-10-10T00:00:00"}