{"id":"https://openalex.org/W2477669721","doi":"https://doi.org/10.1007/978-3-319-40126-3_22","title":"Reconstruction of Metabolic Models for Liver Cancer Cells","display_name":"Reconstruction of Metabolic Models for Liver Cancer Cells","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2477669721","doi":"https://doi.org/10.1007/978-3-319-40126-3_22","mag":"2477669721"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-319-40126-3_22","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-40126-3_22","pdf_url":null,"source":{"id":"https://openalex.org/S2764905038","display_name":"Advances in intelligent systems and computing","issn_l":"2194-5357","issn":["2194-5357","2194-5365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Intelligent Systems and Computing","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100785146","display_name":"Jorge Ferreira","orcid":"https://orcid.org/0000-0002-5132-1651"},"institutions":[{"id":"https://openalex.org/I99682543","display_name":"University of Minho","ror":"https://ror.org/037wpkx04","country_code":"PT","type":"education","lineage":["https://openalex.org/I99682543"]}],"countries":["PT"],"is_corresponding":true,"raw_author_name":"Jorge Ferreira","raw_affiliation_strings":["Centre Biological Engineering, University of Minho, Braga, Portugal"],"affiliations":[{"raw_affiliation_string":"Centre Biological Engineering, University of Minho, Braga, Portugal","institution_ids":["https://openalex.org/I99682543"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081208807","display_name":"Sara Correia","orcid":"https://orcid.org/0000-0002-0395-5561"},"institutions":[{"id":"https://openalex.org/I99682543","display_name":"University of Minho","ror":"https://ror.org/037wpkx04","country_code":"PT","type":"education","lineage":["https://openalex.org/I99682543"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Sara Correia","raw_affiliation_strings":["Centre Biological Engineering, University of Minho, Braga, Portugal"],"affiliations":[{"raw_affiliation_string":"Centre Biological Engineering, University of Minho, Braga, Portugal","institution_ids":["https://openalex.org/I99682543"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040524717","display_name":"Miguel Rocha","orcid":"https://orcid.org/0000-0001-8439-8172"},"institutions":[{"id":"https://openalex.org/I99682543","display_name":"University of Minho","ror":"https://ror.org/037wpkx04","country_code":"PT","type":"education","lineage":["https://openalex.org/I99682543"]}],"countries":["PT"],"is_corresponding":false,"raw_author_name":"Miguel Rocha","raw_affiliation_strings":["Centre Biological Engineering, University of Minho, Braga, Portugal","Dep. de Inf.Campus of Gualtar, Universidade do Minho, Braga, Portugal"],"affiliations":[{"raw_affiliation_string":"Centre Biological Engineering, University of Minho, Braga, Portugal","institution_ids":["https://openalex.org/I99682543"]},{"raw_affiliation_string":"Dep. de Inf.Campus of Gualtar, Universidade do Minho, Braga, Portugal","institution_ids":["https://openalex.org/I99682543"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5100785146"],"corresponding_institution_ids":["https://openalex.org/I99682543"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.0584063,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"213","last_page":"221"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.992900013923645,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.991100013256073,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.608392059803009},{"id":"https://openalex.org/keywords/phenotype","display_name":"Phenotype","score":0.5499399304389954},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.4477331042289734},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.44605308771133423},{"id":"https://openalex.org/keywords/hepatocyte","display_name":"Hepatocyte","score":0.4274170398712158},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.4240581691265106},{"id":"https://openalex.org/keywords/pipeline","display_name":"Pipeline (software)","score":0.4162179231643677},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.36872395873069763},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.16313517093658447},{"id":"https://openalex.org/keywords/biochemistry","display_name":"Biochemistry","score":0.16299396753311157},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.10702207684516907},{"id":"https://openalex.org/keywords/in-vitro","display_name":"In vitro","score":0.09161147475242615}],"concepts":[{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.608392059803009},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5499399304389954},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4477331042289734},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.44605308771133423},{"id":"https://openalex.org/C2776200302","wikidata":"https://www.wikidata.org/wiki/Q827450","display_name":"Hepatocyte","level":3,"score":0.4274170398712158},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4240581691265106},{"id":"https://openalex.org/C43521106","wikidata":"https://www.wikidata.org/wiki/Q2165493","display_name":"Pipeline (software)","level":2,"score":0.4162179231643677},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.36872395873069763},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16313517093658447},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16299396753311157},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10702207684516907},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.09161147475242615},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1007/978-3-319-40126-3_22","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-40126-3_22","pdf_url":null,"source":{"id":"https://openalex.org/S2764905038","display_name":"Advances in intelligent systems and computing","issn_l":"2194-5357","issn":["2194-5357","2194-5365"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Intelligent Systems and Computing","raw_type":"book-chapter"},{"id":"pmh:oai:repositorium.sdum.uminho.pt:1822/44785","is_oa":false,"landing_page_url":"http://hdl.handle.net/1822/44785","pdf_url":null,"source":{"id":"https://openalex.org/S4306400354","display_name":"Reposit\u00f3riUM (Universidade do Minho)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I99682543","host_organization_name":"University of Minho","host_organization_lineage":["https://openalex.org/I99682543"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"conference paper"},{"id":"pmh:oai:repositorium.uminho.pt:1822/44785","is_oa":false,"landing_page_url":"https://hdl.handle.net/1822/44785","pdf_url":null,"source":{"id":"https://openalex.org/S4306402433","display_name":"Portuguese National Funding Agency for Science, Research and Technology (RCAAP Project by FCT)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"conference paper"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.5699999928474426,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W1965712234","https://openalex.org/W1968399600","https://openalex.org/W1969067437","https://openalex.org/W1982309495","https://openalex.org/W1996529795","https://openalex.org/W2009282793","https://openalex.org/W2036181747","https://openalex.org/W2067094344","https://openalex.org/W2072585523","https://openalex.org/W2078355959","https://openalex.org/W2081010896","https://openalex.org/W2099787654","https://openalex.org/W2103950919","https://openalex.org/W2104108767","https://openalex.org/W2106787323","https://openalex.org/W2124653577","https://openalex.org/W2132151783","https://openalex.org/W2132218677","https://openalex.org/W2133730856","https://openalex.org/W2134394193","https://openalex.org/W2144589197","https://openalex.org/W2153349010","https://openalex.org/W2170974939","https://openalex.org/W2254469873","https://openalex.org/W4243536482","https://openalex.org/W4246739026"],"related_works":["https://openalex.org/W2395877311","https://openalex.org/W3141792278","https://openalex.org/W3037187668","https://openalex.org/W3140535278","https://openalex.org/W4250971390","https://openalex.org/W2146636675","https://openalex.org/W2387479390","https://openalex.org/W3144326514","https://openalex.org/W2050689325","https://openalex.org/W2076122407"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1}],"updated_date":"2026-04-05T17:49:38.594831","created_date":"2025-10-10T00:00:00"}