{"id":"https://openalex.org/W2481746403","doi":"https://doi.org/10.1007/978-3-319-39441-1_11","title":"Topological Analysis of Amplicon Structure in Comparative Genomic Hybridization (CGH) Data: An Application to ERBB2/HER2/NEU Amplified Tumors","display_name":"Topological Analysis of Amplicon Structure in Comparative Genomic Hybridization (CGH) Data: An Application to ERBB2/HER2/NEU Amplified Tumors","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2481746403","doi":"https://doi.org/10.1007/978-3-319-39441-1_11","mag":"2481746403"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-319-39441-1_11","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-39441-1_11","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091718678","display_name":"Sergio Ardanza-Trevijano","orcid":"https://orcid.org/0000-0003-2827-5383"},"institutions":[{"id":"https://openalex.org/I88155538","display_name":"Universidad de Navarra","ror":"https://ror.org/02rxc7m23","country_code":"ES","type":"education","lineage":["https://openalex.org/I88155538"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Sergio Ardanza-Trevijano","raw_affiliation_strings":["Department of Physics and Applied Mathematics, University of Navarra, 31080, Pamplona, Spain"],"affiliations":[{"raw_affiliation_string":"Department of Physics and Applied Mathematics, University of Navarra, 31080, Pamplona, Spain","institution_ids":["https://openalex.org/I88155538"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110430340","display_name":"G. Montero Gonz\u00e1lez","orcid":null},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Georgina Gonzalez","raw_affiliation_strings":["Department of Molecular and Cellular Biology, University of California Davis, One Shields Avenue, Davis, CA, 95616, USA"],"affiliations":[{"raw_affiliation_string":"Department of Molecular and Cellular Biology, University of California Davis, One Shields Avenue, Davis, CA, 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058720973","display_name":"Tyler Borrman","orcid":"https://orcid.org/0000-0001-7386-8159"},"institutions":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tyler Borrman","raw_affiliation_strings":["Medical School, University of Massachusetts, 368 Plantation Street, Worcester, MA, 01605, USA"],"affiliations":[{"raw_affiliation_string":"Medical School, University of Massachusetts, 368 Plantation Street, Worcester, MA, 01605, USA","institution_ids":["https://openalex.org/I166722992"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035599648","display_name":"Juan Luis Garc\u0131\u0301a","orcid":"https://orcid.org/0000-0002-2146-5726"},"institutions":[{"id":"https://openalex.org/I4210138819","display_name":"Centro de Investigaci\u00f3n del C\u00e1ncer","ror":"https://ror.org/04rxrdv16","country_code":"ES","type":"facility","lineage":["https://openalex.org/I134820265","https://openalex.org/I184999862","https://openalex.org/I4210138819"]},{"id":"https://openalex.org/I184999862","display_name":"Universidad de Salamanca","ror":"https://ror.org/02f40zc51","country_code":"ES","type":"education","lineage":["https://openalex.org/I184999862"]}],"countries":["ES"],"is_corresponding":false,"raw_author_name":"Juan Luis Garcia","raw_affiliation_strings":["Centro de Investigaci\u00f3n del Cancer, Universidad de Salamanca, 37007, Salamanca, Spain"],"affiliations":[{"raw_affiliation_string":"Centro de Investigaci\u00f3n del Cancer, Universidad de Salamanca, 37007, Salamanca, Spain","institution_ids":["https://openalex.org/I4210138819","https://openalex.org/I184999862"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077553966","display_name":"Javier Arsuaga","orcid":"https://orcid.org/0000-0002-4979-8215"},"institutions":[{"id":"https://openalex.org/I84218800","display_name":"University of California, Davis","ror":"https://ror.org/05rrcem69","country_code":"US","type":"education","lineage":["https://openalex.org/I84218800"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Javier Arsuaga","raw_affiliation_strings":["Department of Mathematics, University of California Davis, One Shields Avenue, Davis, CA, 95616, USA","Department of Molecular and Cellular Biology, University of California Davis, One Shields Avenue, Davis, CA, 95616, USA"],"affiliations":[{"raw_affiliation_string":"Department of Mathematics, University of California Davis, One Shields Avenue, Davis, CA, 95616, USA","institution_ids":["https://openalex.org/I84218800"]},{"raw_affiliation_string":"Department of Molecular and Cellular Biology, University of California Davis, One Shields Avenue, Davis, CA, 95616, USA","institution_ids":["https://openalex.org/I84218800"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5077553966"],"corresponding_institution_ids":["https://openalex.org/I84218800"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.07142857,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"113","last_page":"129"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11213","display_name":"Genomic variations and chromosomal abnormalities","score":0.9995999932289124,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9952999949455261,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":0.9925000071525574,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/amplicon","display_name":"Amplicon","score":0.8909773826599121},{"id":"https://openalex.org/keywords/comparative-genomic-hybridization","display_name":"Comparative genomic hybridization","score":0.7407456636428833},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.46166732907295227},{"id":"https://openalex.org/keywords/homology","display_name":"Homology (biology)","score":0.45749980211257935},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.43405574560165405},{"id":"https://openalex.org/keywords/gene-duplication","display_name":"Gene duplication","score":0.4225327968597412},{"id":"https://openalex.org/keywords/copy-number-variation","display_name":"Copy-number variation","score":0.4102243483066559},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.39992377161979675},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.3665093779563904},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3481699526309967},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.33095839619636536},{"id":"https://openalex.org/keywords/polymerase-chain-reaction","display_name":"Polymerase chain reaction","score":0.11756458878517151}],"concepts":[{"id":"https://openalex.org/C8185291","wikidata":"https://www.wikidata.org/wiki/Q2844457","display_name":"Amplicon","level":4,"score":0.8909773826599121},{"id":"https://openalex.org/C124942203","wikidata":"https://www.wikidata.org/wiki/Q656638","display_name":"Comparative genomic hybridization","level":4,"score":0.7407456636428833},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.46166732907295227},{"id":"https://openalex.org/C165525559","wikidata":"https://www.wikidata.org/wiki/Q224180","display_name":"Homology (biology)","level":3,"score":0.45749980211257935},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.43405574560165405},{"id":"https://openalex.org/C7602840","wikidata":"https://www.wikidata.org/wiki/Q746284","display_name":"Gene duplication","level":3,"score":0.4225327968597412},{"id":"https://openalex.org/C120821319","wikidata":"https://www.wikidata.org/wiki/Q1501491","display_name":"Copy-number variation","level":4,"score":0.4102243483066559},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.39992377161979675},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.3665093779563904},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3481699526309967},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.33095839619636536},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.11756458878517151}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-319-39441-1_11","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-39441-1_11","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.7799999713897705}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W107886322","https://openalex.org/W1520417253","https://openalex.org/W1832363463","https://openalex.org/W1872613111","https://openalex.org/W1978703991","https://openalex.org/W1983781571","https://openalex.org/W1985794577","https://openalex.org/W1986268755","https://openalex.org/W1986354050","https://openalex.org/W1988485005","https://openalex.org/W2011298649","https://openalex.org/W2016299037","https://openalex.org/W2051904177","https://openalex.org/W2054857758","https://openalex.org/W2058316685","https://openalex.org/W2058830224","https://openalex.org/W2066721762","https://openalex.org/W2068174699","https://openalex.org/W2070083767","https://openalex.org/W2074276412","https://openalex.org/W2076356585","https://openalex.org/W2078993948","https://openalex.org/W2079360110","https://openalex.org/W2085511145","https://openalex.org/W2086486491","https://openalex.org/W2088891952","https://openalex.org/W2091330544","https://openalex.org/W2099747853","https://openalex.org/W2100725331","https://openalex.org/W2102368730","https://openalex.org/W2107626316","https://openalex.org/W2110065044","https://openalex.org/W2110359348","https://openalex.org/W2120552178","https://openalex.org/W2122593356","https://openalex.org/W2127710810","https://openalex.org/W2133174470","https://openalex.org/W2141305489","https://openalex.org/W2143186560","https://openalex.org/W2153906117","https://openalex.org/W2157878484","https://openalex.org/W2167925280","https://openalex.org/W2343983168","https://openalex.org/W2561675875"],"related_works":["https://openalex.org/W2081420039","https://openalex.org/W2010401695","https://openalex.org/W2028976524","https://openalex.org/W2140795153","https://openalex.org/W2413147539","https://openalex.org/W3165689115","https://openalex.org/W2108754964","https://openalex.org/W97043878","https://openalex.org/W4280645807","https://openalex.org/W1963487910"],"abstract_inverted_index":null,"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}