{"id":"https://openalex.org/W2398336133","doi":"https://doi.org/10.1007/978-3-319-31744-1_12","title":"Multigene P-value Integration Based on SNPs Investigation for Seeking Radiosensitivity Signatures","display_name":"Multigene P-value Integration Based on SNPs Investigation for Seeking Radiosensitivity Signatures","publication_year":2016,"publication_date":"2016-01-01","ids":{"openalex":"https://openalex.org/W2398336133","doi":"https://doi.org/10.1007/978-3-319-31744-1_12","mag":"2398336133"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-319-31744-1_12","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-31744-1_12","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5014860660","display_name":"Joanna \u017by\u0142a","orcid":"https://orcid.org/0000-0002-2895-7969"},"institutions":[{"id":"https://openalex.org/I119004910","display_name":"Silesian University of Technology","ror":"https://ror.org/02dyjk442","country_code":"PL","type":"education","lineage":["https://openalex.org/I119004910"]}],"countries":["PL"],"is_corresponding":true,"raw_author_name":"Joanna Zyla","raw_affiliation_strings":["Data Mining Group, Institute of Automatic Control, Silesian University of Technology, Gliwice, ul. Akademicka 16, 44-100, Gliwice, Poland"],"affiliations":[{"raw_affiliation_string":"Data Mining Group, Institute of Automatic Control, Silesian University of Technology, Gliwice, ul. Akademicka 16, 44-100, Gliwice, Poland","institution_ids":["https://openalex.org/I119004910"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011581548","display_name":"Christophe Badie","orcid":"https://orcid.org/0000-0003-4572-5008"},"institutions":[{"id":"https://openalex.org/I348769827","display_name":"Public Health England","ror":"https://ror.org/00vbvha87","country_code":"GB","type":"government","lineage":["https://openalex.org/I1311074006","https://openalex.org/I348769827"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Christophe Badie","raw_affiliation_strings":["Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Didcot, Chilton, Oxfordshire, OX11 ORQ, UK"],"affiliations":[{"raw_affiliation_string":"Centre for Radiation, Chemical and Environmental Hazards, Public Health England, Didcot, Chilton, Oxfordshire, OX11 ORQ, UK","institution_ids":["https://openalex.org/I348769827"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007141199","display_name":"Ghazi Alsbeih","orcid":"https://orcid.org/0000-0002-2128-6293"},"institutions":[{"id":"https://openalex.org/I2800965796","display_name":"King Faisal Specialist Hospital & Research Centre","ror":"https://ror.org/05n0wgt02","country_code":"SA","type":"healthcare","lineage":["https://openalex.org/I2800965796"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Ghazi Alsbeih","raw_affiliation_strings":["Radiation Biology Section, Biomedical Physics Department, King Faisal Specialist Hospital and Research Centre, Riyadh, 11211, Kingdom of Saudi Arabia"],"affiliations":[{"raw_affiliation_string":"Radiation Biology Section, Biomedical Physics Department, King Faisal Specialist Hospital and Research Centre, Riyadh, 11211, Kingdom of Saudi Arabia","institution_ids":["https://openalex.org/I2800965796"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5027451254","display_name":"Joanna Pola\u0144ska","orcid":"https://orcid.org/0000-0001-8004-9864"},"institutions":[{"id":"https://openalex.org/I119004910","display_name":"Silesian University of Technology","ror":"https://ror.org/02dyjk442","country_code":"PL","type":"education","lineage":["https://openalex.org/I119004910"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Joanna Polanska","raw_affiliation_strings":["Data Mining Group, Institute of Automatic Control, Silesian University of Technology, Gliwice, ul. Akademicka 16, 44-100, Gliwice, Poland"],"affiliations":[{"raw_affiliation_string":"Data Mining Group, Institute of Automatic Control, Silesian University of Technology, Gliwice, ul. Akademicka 16, 44-100, Gliwice, Poland","institution_ids":["https://openalex.org/I119004910"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5014860660"],"corresponding_institution_ids":["https://openalex.org/I119004910"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.01845444,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"125","last_page":"134"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways","score":0.9969000220298767,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9909999966621399,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11359","display_name":"Effects of Radiation Exposure","score":0.9757000207901001,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/radiosensitivity","display_name":"Radiosensitivity","score":0.7729542255401611},{"id":"https://openalex.org/keywords/radiation-therapy","display_name":"Radiation therapy","score":0.6260371208190918},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphism","display_name":"Single-nucleotide polymorphism","score":0.5973863005638123},{"id":"https://openalex.org/keywords/kras","display_name":"KRAS","score":0.559046745300293},{"id":"https://openalex.org/keywords/snp","display_name":"SNP","score":0.5435710549354553},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.500852108001709},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.46760478615760803},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.46488022804260254},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.4480307400226593},{"id":"https://openalex.org/keywords/ionizing-radiation","display_name":"Ionizing radiation","score":0.4298091232776642},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3574073910713196},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3320017457008362},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.32873862981796265},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.2772443890571594},{"id":"https://openalex.org/keywords/mutation","display_name":"Mutation","score":0.2164115309715271},{"id":"https://openalex.org/keywords/genotype","display_name":"Genotype","score":0.20243176817893982},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.1724485158920288},{"id":"https://openalex.org/keywords/irradiation","display_name":"Irradiation","score":0.16362416744232178},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.13452720642089844},{"id":"https://openalex.org/keywords/physics","display_name":"Physics","score":0.12171715497970581}],"concepts":[{"id":"https://openalex.org/C206684579","wikidata":"https://www.wikidata.org/wiki/Q4387689","display_name":"Radiosensitivity","level":3,"score":0.7729542255401611},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.6260371208190918},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.5973863005638123},{"id":"https://openalex.org/C2781187634","wikidata":"https://www.wikidata.org/wiki/Q20969980","display_name":"KRAS","level":4,"score":0.559046745300293},{"id":"https://openalex.org/C139275648","wikidata":"https://www.wikidata.org/wiki/Q17134011","display_name":"SNP","level":5,"score":0.5435710549354553},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.500852108001709},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.46760478615760803},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.46488022804260254},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.4480307400226593},{"id":"https://openalex.org/C18231593","wikidata":"https://www.wikidata.org/wiki/Q186161","display_name":"Ionizing radiation","level":3,"score":0.4298091232776642},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3574073910713196},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3320017457008362},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.32873862981796265},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2772443890571594},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.2164115309715271},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.20243176817893982},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1724485158920288},{"id":"https://openalex.org/C111337013","wikidata":"https://www.wikidata.org/wiki/Q2737837","display_name":"Irradiation","level":2,"score":0.16362416744232178},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13452720642089844},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.12171715497970581},{"id":"https://openalex.org/C185544564","wikidata":"https://www.wikidata.org/wiki/Q81197","display_name":"Nuclear physics","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-319-31744-1_12","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-31744-1_12","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.6800000071525574,"display_name":"Good health and well-being"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W115055913","https://openalex.org/W572215686","https://openalex.org/W574736066","https://openalex.org/W1533179050","https://openalex.org/W1560020441","https://openalex.org/W1587447328","https://openalex.org/W1636392194","https://openalex.org/W1776458718","https://openalex.org/W1973740519","https://openalex.org/W1981139027","https://openalex.org/W1995358091","https://openalex.org/W2008998482","https://openalex.org/W2021807197","https://openalex.org/W2027044610","https://openalex.org/W2082992860","https://openalex.org/W2089175718","https://openalex.org/W2108205507","https://openalex.org/W2130410032","https://openalex.org/W2142114378","https://openalex.org/W2156996716","https://openalex.org/W2158785918","https://openalex.org/W2167806431","https://openalex.org/W2313814802","https://openalex.org/W2330978860","https://openalex.org/W2911453016","https://openalex.org/W4230174249","https://openalex.org/W4300487841","https://openalex.org/W6676661585"],"related_works":["https://openalex.org/W2051321470","https://openalex.org/W1997352593","https://openalex.org/W2143489661","https://openalex.org/W3016573916","https://openalex.org/W4281711902","https://openalex.org/W3206555169","https://openalex.org/W2070581548","https://openalex.org/W3157359833","https://openalex.org/W2413660786","https://openalex.org/W3024317680"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}