{"id":"https://openalex.org/W51469642","doi":"https://doi.org/10.1007/978-3-319-05269-4_9","title":"AptaCluster \u2013 A Method to Cluster HT-SELEX Aptamer Pools and Lessons from Its Application","display_name":"AptaCluster \u2013 A Method to Cluster HT-SELEX Aptamer Pools and Lessons from Its Application","publication_year":2014,"publication_date":"2014-01-01","ids":{"openalex":"https://openalex.org/W51469642","doi":"https://doi.org/10.1007/978-3-319-05269-4_9","mag":"51469642","pmid":"https://pubmed.ncbi.nlm.nih.gov/25558474"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-319-05269-4_9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-05269-4_9","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4281958","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5050306634","display_name":"Jan Hoinka","orcid":"https://orcid.org/0000-0002-0652-381X"},"institutions":[{"id":"https://openalex.org/I4210109390","display_name":"National Center for Biotechnology Information","ror":"https://ror.org/02meqm098","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I2800548410","https://openalex.org/I4210109390"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jan Hoinka","raw_affiliation_strings":["National Center of Biotechnology Information, National Library of Medicine, NIH, Bethesda MD 20894, USA","National Center of Biotechnology Information, National Library of Medicine, NIH, Bethesda, USA#TAB#"],"affiliations":[{"raw_affiliation_string":"National Center of Biotechnology Information, National Library of Medicine, NIH, Bethesda MD 20894, USA","institution_ids":["https://openalex.org/I4210109390"]},{"raw_affiliation_string":"National Center of Biotechnology Information, National Library of Medicine, NIH, Bethesda, USA#TAB#","institution_ids":["https://openalex.org/I4210109390"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102822234","display_name":"Alexey Berezhnoy","orcid":"https://orcid.org/0000-0002-7886-5181"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alexey Berezhnoy","raw_affiliation_strings":["Department of Microbiology & Immunology, University of Miami Miller School of Medicine, Miami, Florida 33101, USA","Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, USA"],"affiliations":[{"raw_affiliation_string":"Department of Microbiology & Immunology, University of Miami Miller School of Medicine, Miami, Florida 33101, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091041425","display_name":"Zuben E. Sauna","orcid":"https://orcid.org/0000-0001-8202-5188"},"institutions":[{"id":"https://openalex.org/I1318287680","display_name":"Center for Biologics Evaluation and Research","ror":"https://ror.org/02nr3fr97","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1318287680","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Zuben E. Sauna","raw_affiliation_strings":["Laboratory of Hemostasis, Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA","Laboratory of Hemostasis, Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, USA#TAB#"],"affiliations":[{"raw_affiliation_string":"Laboratory of Hemostasis, Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, USA","institution_ids":["https://openalex.org/I1318287680"]},{"raw_affiliation_string":"Laboratory of Hemostasis, Division of Hematology, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, USA#TAB#","institution_ids":["https://openalex.org/I1318287680"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068892519","display_name":"Eli Gilboa","orcid":"https://orcid.org/0000-0002-2645-8154"},"institutions":[{"id":"https://openalex.org/I145608581","display_name":"University of Miami","ror":"https://ror.org/02dgjyy92","country_code":"US","type":"education","lineage":["https://openalex.org/I145608581"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Eli Gilboa","raw_affiliation_strings":["Department of Microbiology & Immunology, University of Miami Miller School of Medicine, Miami, USA","Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, USA"],"affiliations":[{"raw_affiliation_string":"Department of Microbiology & Immunology, University of Miami Miller School of Medicine, Miami, USA","institution_ids":["https://openalex.org/I145608581"]},{"raw_affiliation_string":"Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, USA","institution_ids":["https://openalex.org/I145608581"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089548776","display_name":"Teresa M. Przytycka","orcid":"https://orcid.org/0000-0002-6261-277X"},"institutions":[{"id":"https://openalex.org/I4210109390","display_name":"National Center for Biotechnology Information","ror":"https://ror.org/02meqm098","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I2800548410","https://openalex.org/I4210109390"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Teresa M. Przytycka","raw_affiliation_strings":["National Center of Biotechnology Information, National Library of Medicine, NIH, Bethesda, USA","National Center of Biotechnology Information, National Library of Medicine, NIH, Bethesda, USA#TAB#"],"affiliations":[{"raw_affiliation_string":"National Center of Biotechnology Information, National Library of Medicine, NIH, Bethesda, USA","institution_ids":["https://openalex.org/I4210109390"]},{"raw_affiliation_string":"National Center of Biotechnology Information, National Library of Medicine, NIH, Bethesda, USA#TAB#","institution_ids":["https://openalex.org/I4210109390"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5050306634"],"corresponding_institution_ids":["https://openalex.org/I4210109390"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":13.9323,"has_fulltext":false,"cited_by_count":105,"citation_normalized_percentile":{"value":0.9909618,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":97,"max":99},"biblio":{"volume":"8394","issue":null,"first_page":"115","last_page":"128"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9997000098228455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systematic-evolution-of-ligands-by-exponential-enrichment","display_name":"Systematic evolution of ligands by exponential enrichment","score":0.9655898809432983},{"id":"https://openalex.org/keywords/aptamer","display_name":"Aptamer","score":0.8298126459121704},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6633075475692749},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.61266028881073},{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.5843114852905273},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4680927097797394},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.24427726864814758},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.2383200228214264},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.10326957702636719},{"id":"https://openalex.org/keywords/rna","display_name":"RNA","score":0.07223665714263916}],"concepts":[{"id":"https://openalex.org/C122682173","wikidata":"https://www.wikidata.org/wiki/Q907101","display_name":"Systematic evolution of ligands by exponential enrichment","level":4,"score":0.9655898809432983},{"id":"https://openalex.org/C128972844","wikidata":"https://www.wikidata.org/wiki/Q418722","display_name":"Aptamer","level":2,"score":0.8298126459121704},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6633075475692749},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.61266028881073},{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.5843114852905273},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4680927097797394},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.24427726864814758},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.2383200228214264},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.10326957702636719},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.07223665714263916},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1007/978-3-319-05269-4_9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-319-05269-4_9","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},{"id":"pmid:25558474","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/25558474","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research in computational molecular biology : ... Annual International Conference, RECOMB ... : proceedings. RECOMB (Conference : 2005- )","raw_type":null},{"id":"pmh:oai:pubmedcentral.nih.gov:4281958","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4281958","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Res Comput Mol Biol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:4281958","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4281958","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Res Comput Mol Biol","raw_type":"Text"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W3240003","https://openalex.org/W29709319","https://openalex.org/W1502916507","https://openalex.org/W1566992315","https://openalex.org/W1984093755","https://openalex.org/W1984936484","https://openalex.org/W2007081196","https://openalex.org/W2013414181","https://openalex.org/W2038276547","https://openalex.org/W2048907669","https://openalex.org/W2049543568","https://openalex.org/W2051003176","https://openalex.org/W2085251576","https://openalex.org/W2104525153","https://openalex.org/W2119342775","https://openalex.org/W2152121035","https://openalex.org/W2290761674"],"related_works":["https://openalex.org/W4313237059","https://openalex.org/W2392306680","https://openalex.org/W4311808994","https://openalex.org/W3093450845","https://openalex.org/W4283324873","https://openalex.org/W4307216241","https://openalex.org/W3041313328","https://openalex.org/W3108749156","https://openalex.org/W4304099287","https://openalex.org/W2418123252"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":12},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":10},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":7},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":11},{"year":2015,"cited_by_count":11}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}