{"id":"https://openalex.org/W7117964529","doi":"https://doi.org/10.1007/978-3-032-09569-5_31","title":"Disentanglement of\u00a0Biological and\u00a0Technical Factors via\u00a0Latent Space Rotation in\u00a0Clinical Imaging Improves Disease Pattern Discovery","display_name":"Disentanglement of\u00a0Biological and\u00a0Technical Factors via\u00a0Latent Space Rotation in\u00a0Clinical Imaging Improves Disease Pattern Discovery","publication_year":2026,"publication_date":"2026-01-01","ids":{"openalex":"https://openalex.org/W7117964529","doi":"https://doi.org/10.1007/978-3-032-09569-5_31"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-032-09569-5_31","is_oa":true,"landing_page_url":"https://doi.org/10.1007/978-3-032-09569-5_31","pdf_url":"https://link.springer.com/content/pdf/10.1007/978-3-032-09569-5_31.pdf","source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://link.springer.com/content/pdf/10.1007/978-3-032-09569-5_31.pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041400975","display_name":"Jeanny Pan","orcid":null},"institutions":[{"id":"https://openalex.org/I161878677","display_name":"Austrian Research Institute for Artificial Intelligence","ror":"https://ror.org/04j47vk14","country_code":"AT","type":"facility","lineage":["https://openalex.org/I161878677","https://openalex.org/I4210107880"]},{"id":"https://openalex.org/I4210118047","display_name":"Laboratoire d\u2019Imagerie Biom\u00e9dicale","ror":"https://ror.org/02b9znm90","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210118047"]}],"countries":["AT","FR"],"is_corresponding":true,"raw_author_name":"Jeanny Pan","raw_affiliation_strings":["Comprehensive Center for Artificial Intelligence in Medicine, Vienna, Austria","Computational Imaging Research Lab, Department for Biomedical Imaging and Image-guided Therapy, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Center for Artificial Intelligence in Medicine, Vienna, Austria","institution_ids":["https://openalex.org/I161878677"]},{"raw_affiliation_string":"Computational Imaging Research Lab, Department for Biomedical Imaging and Image-guided Therapy, Vienna, Austria","institution_ids":["https://openalex.org/I4210118047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003998290","display_name":"Philipp Seeb\u00f6ck","orcid":"https://orcid.org/0000-0001-5512-5810"},"institutions":[{"id":"https://openalex.org/I161878677","display_name":"Austrian Research Institute for Artificial Intelligence","ror":"https://ror.org/04j47vk14","country_code":"AT","type":"facility","lineage":["https://openalex.org/I161878677","https://openalex.org/I4210107880"]},{"id":"https://openalex.org/I4210118047","display_name":"Laboratoire d\u2019Imagerie Biom\u00e9dicale","ror":"https://ror.org/02b9znm90","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210118047"]}],"countries":["AT","FR"],"is_corresponding":false,"raw_author_name":"Philipp Seeb\u00f6ck","raw_affiliation_strings":["Comprehensive Center for Artificial Intelligence in Medicine, Vienna, Austria","Computational Imaging Research Lab, Department for Biomedical Imaging and Image-guided Therapy, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Center for Artificial Intelligence in Medicine, Vienna, Austria","institution_ids":["https://openalex.org/I161878677"]},{"raw_affiliation_string":"Computational Imaging Research Lab, Department for Biomedical Imaging and Image-guided Therapy, Vienna, Austria","institution_ids":["https://openalex.org/I4210118047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012700563","display_name":"Christoph F\u00fcrb\u00f6ck","orcid":null},"institutions":[{"id":"https://openalex.org/I161878677","display_name":"Austrian Research Institute for Artificial Intelligence","ror":"https://ror.org/04j47vk14","country_code":"AT","type":"facility","lineage":["https://openalex.org/I161878677","https://openalex.org/I4210107880"]},{"id":"https://openalex.org/I4210118047","display_name":"Laboratoire d\u2019Imagerie Biom\u00e9dicale","ror":"https://ror.org/02b9znm90","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210118047"]}],"countries":["AT","FR"],"is_corresponding":false,"raw_author_name":"Christoph F\u00fcrb\u00f6ck","raw_affiliation_strings":["Comprehensive Center for Artificial Intelligence in Medicine, Vienna, Austria","Computational Imaging Research Lab, Department for Biomedical Imaging and Image-guided Therapy, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Center for Artificial Intelligence in Medicine, Vienna, Austria","institution_ids":["https://openalex.org/I161878677"]},{"raw_affiliation_string":"Computational Imaging Research Lab, Department for Biomedical Imaging and Image-guided Therapy, Vienna, Austria","institution_ids":["https://openalex.org/I4210118047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046226628","display_name":"Svitlana Pochepnia","orcid":"https://orcid.org/0009-0005-9496-1295"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Svitlana Pochepnia","raw_affiliation_strings":["Division of General and Pediatric Radiology, Department for Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of General and Pediatric Radiology, Department for Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076430371","display_name":"Jennifer Straub","orcid":"https://orcid.org/0000-0002-2576-1717"},"institutions":[{"id":"https://openalex.org/I161878677","display_name":"Austrian Research Institute for Artificial Intelligence","ror":"https://ror.org/04j47vk14","country_code":"AT","type":"facility","lineage":["https://openalex.org/I161878677","https://openalex.org/I4210107880"]},{"id":"https://openalex.org/I4210118047","display_name":"Laboratoire d\u2019Imagerie Biom\u00e9dicale","ror":"https://ror.org/02b9znm90","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210118047"]}],"countries":["AT","FR"],"is_corresponding":false,"raw_author_name":"Jennifer Straub","raw_affiliation_strings":["Comprehensive Center for Artificial Intelligence in Medicine, Vienna, Austria","Computational Imaging Research Lab, Department for Biomedical Imaging and Image-guided Therapy, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Center for Artificial Intelligence in Medicine, Vienna, Austria","institution_ids":["https://openalex.org/I161878677"]},{"raw_affiliation_string":"Computational Imaging Research Lab, Department for Biomedical Imaging and Image-guided Therapy, Vienna, Austria","institution_ids":["https://openalex.org/I4210118047"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015345650","display_name":"Lucian Beer","orcid":"https://orcid.org/0000-0003-4388-7580"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Lucian Beer","raw_affiliation_strings":["Division of General and Pediatric Radiology, Department for Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of General and Pediatric Radiology, Department for Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014530467","display_name":"Helmut Prosch","orcid":"https://orcid.org/0000-0002-6119-6364"},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Helmut Prosch","raw_affiliation_strings":["Division of General and Pediatric Radiology, Department for Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of General and Pediatric Radiology, Department for Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5121509162","display_name":"Georg Langs","orcid":null},"institutions":[{"id":"https://openalex.org/I161878677","display_name":"Austrian Research Institute for Artificial Intelligence","ror":"https://ror.org/04j47vk14","country_code":"AT","type":"facility","lineage":["https://openalex.org/I161878677","https://openalex.org/I4210107880"]},{"id":"https://openalex.org/I4210118047","display_name":"Laboratoire d\u2019Imagerie Biom\u00e9dicale","ror":"https://ror.org/02b9znm90","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210096427","https://openalex.org/I4210118047"]}],"countries":["AT","FR"],"is_corresponding":false,"raw_author_name":"Georg Langs","raw_affiliation_strings":["Comprehensive Center for Artificial Intelligence in Medicine, Vienna, Austria","Computational Imaging Research Lab, Department for Biomedical Imaging and Image-guided Therapy, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Comprehensive Center for Artificial Intelligence in Medicine, Vienna, Austria","institution_ids":["https://openalex.org/I161878677"]},{"raw_affiliation_string":"Computational Imaging Research Lab, Department for Biomedical Imaging and Image-guided Therapy, Vienna, Austria","institution_ids":["https://openalex.org/I4210118047"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5041400975"],"corresponding_institution_ids":["https://openalex.org/I161878677","https://openalex.org/I4210118047"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":{"value":5000,"currency":"EUR","value_usd":5392},"fwci":65.9286,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":{"value":0.98698482,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":98},"biblio":{"volume":null,"issue":null,"first_page":"309","last_page":"319"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.38589999079704285,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12422","display_name":"Radiomics and Machine Learning in Medical Imaging","score":0.38589999079704285,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.24570000171661377,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11775","display_name":"COVID-19 diagnosis using AI","score":0.10599999874830246,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/representation","display_name":"Representation (politics)","score":0.5088000297546387},{"id":"https://openalex.org/keywords/domain","display_name":"Domain (mathematical analysis)","score":0.5005000233650208},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.4790000021457672},{"id":"https://openalex.org/keywords/medical-imaging","display_name":"Medical imaging","score":0.4526999890804291},{"id":"https://openalex.org/keywords/external-data-representation","display_name":"External Data Representation","score":0.41269999742507935},{"id":"https://openalex.org/keywords/rotation","display_name":"Rotation (mathematics)","score":0.39070001244544983},{"id":"https://openalex.org/keywords/consistency","display_name":"Consistency (knowledge bases)","score":0.3901999890804291},{"id":"https://openalex.org/keywords/biological-data","display_name":"Biological data","score":0.3695000112056732},{"id":"https://openalex.org/keywords/code","display_name":"Code (set theory)","score":0.35899999737739563}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.8306000232696533},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6258000135421753},{"id":"https://openalex.org/C2776359362","wikidata":"https://www.wikidata.org/wiki/Q2145286","display_name":"Representation (politics)","level":3,"score":0.5088000297546387},{"id":"https://openalex.org/C36503486","wikidata":"https://www.wikidata.org/wiki/Q11235244","display_name":"Domain (mathematical analysis)","level":2,"score":0.5005000233650208},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.4790000021457672},{"id":"https://openalex.org/C31601959","wikidata":"https://www.wikidata.org/wiki/Q931309","display_name":"Medical imaging","level":2,"score":0.4526999890804291},{"id":"https://openalex.org/C116409475","wikidata":"https://www.wikidata.org/wiki/Q1385056","display_name":"External Data Representation","level":2,"score":0.41269999742507935},{"id":"https://openalex.org/C74050887","wikidata":"https://www.wikidata.org/wiki/Q848368","display_name":"Rotation (mathematics)","level":2,"score":0.39070001244544983},{"id":"https://openalex.org/C2776436953","wikidata":"https://www.wikidata.org/wiki/Q5163215","display_name":"Consistency (knowledge bases)","level":2,"score":0.3901999890804291},{"id":"https://openalex.org/C201797286","wikidata":"https://www.wikidata.org/wiki/Q4914986","display_name":"Biological data","level":2,"score":0.3695000112056732},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3612000048160553},{"id":"https://openalex.org/C2776760102","wikidata":"https://www.wikidata.org/wiki/Q5139990","display_name":"Code (set theory)","level":3,"score":0.35899999737739563},{"id":"https://openalex.org/C124535831","wikidata":"https://www.wikidata.org/wiki/Q4915074","display_name":"Biomarker discovery","level":4,"score":0.3564999997615814},{"id":"https://openalex.org/C159620131","wikidata":"https://www.wikidata.org/wiki/Q1938983","display_name":"Spatial analysis","level":2,"score":0.3321000039577484},{"id":"https://openalex.org/C89600930","wikidata":"https://www.wikidata.org/wiki/Q1423946","display_name":"Segmentation","level":2,"score":0.3228999972343445},{"id":"https://openalex.org/C164866538","wikidata":"https://www.wikidata.org/wiki/Q367351","display_name":"Cluster (spacecraft)","level":2,"score":0.31610000133514404},{"id":"https://openalex.org/C2779478453","wikidata":"https://www.wikidata.org/wiki/Q6889748","display_name":"Modularity (biology)","level":2,"score":0.3140999972820282},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.2969000041484833},{"id":"https://openalex.org/C2780226545","wikidata":"https://www.wikidata.org/wiki/Q6888030","display_name":"Modality (human\u2013computer interaction)","level":2,"score":0.2921999990940094},{"id":"https://openalex.org/C9652623","wikidata":"https://www.wikidata.org/wiki/Q190109","display_name":"Field (mathematics)","level":2,"score":0.2906999886035919},{"id":"https://openalex.org/C43126263","wikidata":"https://www.wikidata.org/wiki/Q128751","display_name":"Source code","level":2,"score":0.29010000824928284},{"id":"https://openalex.org/C163985040","wikidata":"https://www.wikidata.org/wiki/Q1172399","display_name":"Data acquisition","level":2,"score":0.2865000069141388},{"id":"https://openalex.org/C2777601683","wikidata":"https://www.wikidata.org/wiki/Q6499736","display_name":"Vocabulary","level":2,"score":0.2773999869823456},{"id":"https://openalex.org/C2778572836","wikidata":"https://www.wikidata.org/wiki/Q380933","display_name":"Space (punctuation)","level":2,"score":0.27649998664855957},{"id":"https://openalex.org/C2776145971","wikidata":"https://www.wikidata.org/wiki/Q30673951","display_name":"Labeled data","level":2,"score":0.2639999985694885},{"id":"https://openalex.org/C93361087","wikidata":"https://www.wikidata.org/wiki/Q4426698","display_name":"Data consistency","level":2,"score":0.2635999917984009},{"id":"https://openalex.org/C59404180","wikidata":"https://www.wikidata.org/wiki/Q17013334","display_name":"Feature learning","level":2,"score":0.26100000739097595},{"id":"https://openalex.org/C2779808786","wikidata":"https://www.wikidata.org/wiki/Q6664603","display_name":"Locality","level":2,"score":0.25679999589920044}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-032-09569-5_31","is_oa":true,"landing_page_url":"https://doi.org/10.1007/978-3-032-09569-5_31","pdf_url":"https://link.springer.com/content/pdf/10.1007/978-3-032-09569-5_31.pdf","source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":{"id":"doi:10.1007/978-3-032-09569-5_31","is_oa":true,"landing_page_url":"https://doi.org/10.1007/978-3-032-09569-5_31","pdf_url":"https://link.springer.com/content/pdf/10.1007/978-3-032-09569-5_31.pdf","source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"sustainable_development_goals":[{"score":0.4236948788166046,"id":"https://metadata.un.org/sdg/4","display_name":"Quality Education"}],"awards":[{"id":"https://openalex.org/G612855475","display_name":"Trustworthy AI Tools for the Prediction of Obesity Related Vascular Diseases","funder_award_id":"101080302","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G7737748700","display_name":"Emerging Infectious Lung Disease Monitor","funder_award_id":"P35189","funder_id":"https://openalex.org/F4320321181","funder_display_name":"Austrian Science Fund"}],"funders":[{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321181","display_name":"Austrian Science Fund","ror":"https://ror.org/013tf3c58"},{"id":"https://openalex.org/F4320322679","display_name":"International Atomic Energy Agency","ror":"https://ror.org/02zt1gg83"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W7117964529.pdf","grobid_xml":"https://content.openalex.org/works/W7117964529.grobid-xml"},"referenced_works_count":15,"referenced_works":["https://openalex.org/W1540856690","https://openalex.org/W1995554623","https://openalex.org/W1997786880","https://openalex.org/W2097645701","https://openalex.org/W2137954917","https://openalex.org/W2950086191","https://openalex.org/W2964288524","https://openalex.org/W2998702515","https://openalex.org/W3074741277","https://openalex.org/W3083569266","https://openalex.org/W4235169531","https://openalex.org/W4294723684","https://openalex.org/W4393239042","https://openalex.org/W4401172250","https://openalex.org/W4405092793"],"related_works":[],"abstract_inverted_index":{"Abstract":[0],"Identifying":[1],"new":[2],"disease-related":[3],"patterns":[4],"in":[5,170],"medical":[6],"imaging":[7,41,173],"data":[8,55,86,101],"with":[9],"the":[10,16,60,78,85,104,132,142,153,163],"help":[11],"of":[12,18,62,84,91],"machine":[13],"learning":[14,57],"enlarges":[15],"vocabulary":[17],"recognizable":[19],"findings.":[20],"This":[21,160],"supports":[22],"diagnostic":[23],"and":[24,59,93,127],"prognostic":[25],"assessment.":[26],"However,":[27],"image":[28],"appearance":[29],"varies":[30],"not":[31],"only":[32],"due":[33,39],"to":[34,40,44,75,109,131,144],"biological":[35,92],"differences,":[36],"but":[37],"also":[38],"technology":[42],"linked":[43],"vendors,":[45],"scanning-":[46],"or":[47],"reconstruction":[48],"parameters.":[49],"The":[50],"resulting":[51],"domain":[52,79],"shifts":[53],"impedes":[54],"representation":[56,107],"strategies":[58],"discovery":[61,169],"biologically":[63],"meaningful":[64],"cluster":[65],"appearances.":[66],"To":[67],"address":[68],"these":[69],"challenges,":[70],"we":[71],"introduce":[72],"an":[73],"approach":[74],"actively":[76],"learn":[77],"shift":[80],"via":[81],"post-hoc":[82],"rotation":[83],"latent":[87],"space,":[88],"enabling":[89],"disentanglement":[90],"technical":[94],"factors.":[95],"Results":[96],"on":[97,148,178],"real-world":[98],"heterogeneous":[99],"clinical":[100],"showcase":[102],"that":[103,162],"learned":[105,154],"disentangled":[106],"leads":[108],"stable":[110],"clusters":[111,143],"representing":[112],"tissue-types":[113],"across":[114],"different":[115],"acquisition":[116],"settings.":[117],"Cluster":[118],"consistency":[119],"is":[120,176],"improved":[121],"by":[122],"+19.01%":[123],"(ARI),":[124],"+16.85%":[125],"(NMI),":[126],"+12.39%":[128],"(Dice)":[129],"compared":[130],"entangled":[133],"representation,":[134],"outperforming":[135],"four":[136],"state-of-the-art":[137],"harmonization":[138],"methods.":[139],"When":[140],"using":[141],"quantify":[145],"tissue":[146],"composition":[147],"idiopathic":[149],"pulmonary":[150],"fibrosis":[151],"patients,":[152],"profiles":[155],"enhance":[156],"Cox":[157],"survival":[158],"prediction.":[159],"indicates":[161],"proposed":[164],"label-free":[165],"framework":[166],"facilitates":[167],"biomarker":[168],"multi-center":[171],"routine":[172],"data.":[174],"Code":[175],"available":[177],"GitHub":[179],"https://github.com/cirmuw/latent-space-rotation-disentanglement":[180],".":[181]},"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-05-03T08:25:01.440150","created_date":"2026-01-02T00:00:00"}