{"id":"https://openalex.org/W4403365596","doi":"https://doi.org/10.1007/978-3-031-72083-3_21","title":"Immune-Guided AI for\u00a0Reproducible Regions of\u00a0Interest Selection in\u00a0Multiplex Immunofluorescence Pathology Imaging","display_name":"Immune-Guided AI for\u00a0Reproducible Regions of\u00a0Interest Selection in\u00a0Multiplex Immunofluorescence Pathology Imaging","publication_year":2024,"publication_date":"2024-01-01","ids":{"openalex":"https://openalex.org/W4403365596","doi":"https://doi.org/10.1007/978-3-031-72083-3_21"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-031-72083-3_21","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-031-72083-3_21","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113431621","display_name":"Tanishq Gautam","orcid":null},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tanishq Gautam","raw_affiliation_strings":["The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029074946","display_name":"Karla Iliana Gonz\u00e1lez","orcid":null},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karina P. Gonzalez","raw_affiliation_strings":["Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024723166","display_name":"Maria E. Salvatierra","orcid":null},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maria E. Salvatierra","raw_affiliation_strings":["Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043117364","display_name":"Alejandra G. Serrano","orcid":"https://orcid.org/0000-0001-6759-9239"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alejandra Serrano","raw_affiliation_strings":["Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045480484","display_name":"Pingjun Chen","orcid":"https://orcid.org/0000-0003-0528-1713"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Pingjun Chen","raw_affiliation_strings":["The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006285886","display_name":"Xiaoxi Pan","orcid":"https://orcid.org/0000-0002-6146-5771"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaoxi Pan","raw_affiliation_strings":["Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008136014","display_name":"Yasin Shokrollahi","orcid":"https://orcid.org/0000-0002-2456-7103"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yasin Shokrollahi","raw_affiliation_strings":["The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078763626","display_name":"Sara Ranjbar","orcid":"https://orcid.org/0000-0002-4344-1282"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sara Ranjbar","raw_affiliation_strings":["The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110321777","display_name":"Leticia Rodr\u00edguez","orcid":null},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leticia Rodriguez","raw_affiliation_strings":["The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Patient Mosaic Team","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Patient Mosaic Team","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016000784","display_name":"Luisa M. Solis\u2010Soto","orcid":null},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Luisa Solis-Soto","raw_affiliation_strings":["Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011555338","display_name":"Yinyin Yuan","orcid":"https://orcid.org/0000-0002-8556-4707"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yinyin Yuan","raw_affiliation_strings":["Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030552872","display_name":"Sim\u00f3n P. Castillo","orcid":"https://orcid.org/0000-0002-0606-2160"},"institutions":[{"id":"https://openalex.org/I1343551460","display_name":"The University of Texas MD Anderson Cancer Center","ror":"https://ror.org/04twxam07","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1343551460"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Simon P. Castillo","raw_affiliation_strings":["Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA"],"raw_orcid":"https://orcid.org/0000-0002-0606-2160","affiliations":[{"raw_affiliation_string":"Department of Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]},{"raw_affiliation_string":"The Institute for Data Science in Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, 77098, USA","institution_ids":["https://openalex.org/I1343551460"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":13,"corresponding_author_ids":["https://openalex.org/A5030552872"],"corresponding_institution_ids":["https://openalex.org/I1343551460"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.28538012,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"222","last_page":"231"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9950000047683716,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.9950000047683716,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11289","display_name":"Single-cell and spatial transcriptomics","score":0.992900013923645,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10862","display_name":"AI in cancer detection","score":0.9918000102043152,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/multiplex","display_name":"Multiplex","score":0.785686194896698},{"id":"https://openalex.org/keywords/immunofluorescence","display_name":"Immunofluorescence","score":0.6431953310966492},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6015009880065918},{"id":"https://openalex.org/keywords/selection","display_name":"Selection (genetic algorithm)","score":0.4772234261035919},{"id":"https://openalex.org/keywords/immune-system","display_name":"Immune system","score":0.46684062480926514},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.4229786992073059},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.30775001645088196},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.2053963840007782},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.20332753658294678},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.13380715250968933},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.12175506353378296},{"id":"https://openalex.org/keywords/antibody","display_name":"Antibody","score":0.1206430196762085}],"concepts":[{"id":"https://openalex.org/C2781188995","wikidata":"https://www.wikidata.org/wiki/Q6934982","display_name":"Multiplex","level":2,"score":0.785686194896698},{"id":"https://openalex.org/C2778236600","wikidata":"https://www.wikidata.org/wiki/Q592324","display_name":"Immunofluorescence","level":3,"score":0.6431953310966492},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6015009880065918},{"id":"https://openalex.org/C81917197","wikidata":"https://www.wikidata.org/wiki/Q628760","display_name":"Selection (genetic algorithm)","level":2,"score":0.4772234261035919},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.46684062480926514},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4229786992073059},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.30775001645088196},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2053963840007782},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20332753658294678},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.13380715250968933},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.12175506353378296},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.1206430196762085}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-031-72083-3_21","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-031-72083-3_21","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2","score":0.7400000095367432}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W639708223","https://openalex.org/W2120431466","https://openalex.org/W2141269240","https://openalex.org/W2194775991","https://openalex.org/W2295739065","https://openalex.org/W2408688145","https://openalex.org/W2531409750","https://openalex.org/W2963351448","https://openalex.org/W3033721673","https://openalex.org/W3106654583","https://openalex.org/W4282966980","https://openalex.org/W4317434093","https://openalex.org/W4362693620","https://openalex.org/W4384130825","https://openalex.org/W4385948838","https://openalex.org/W4389042111","https://openalex.org/W6893711219"],"related_works":["https://openalex.org/W2022037402","https://openalex.org/W2395884055","https://openalex.org/W3006199032","https://openalex.org/W1963826946","https://openalex.org/W2087421209","https://openalex.org/W2547948671","https://openalex.org/W2129034889","https://openalex.org/W3043695311","https://openalex.org/W4294738915","https://openalex.org/W159842789"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-06-13T06:13:01.061226","created_date":"2025-10-10T00:00:00"}
