{"id":"https://openalex.org/W4399268134","doi":"https://doi.org/10.1007/978-3-031-61569-6_7","title":"Mapping Signaling Mechanisms in Neurotoxic Injury from Sparsely Sampled Data Using a Constraint Satisfaction Framework","display_name":"Mapping Signaling Mechanisms in Neurotoxic Injury from Sparsely Sampled Data Using a Constraint Satisfaction Framework","publication_year":2024,"publication_date":"2024-01-01","ids":{"openalex":"https://openalex.org/W4399268134","doi":"https://doi.org/10.1007/978-3-031-61569-6_7"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-031-61569-6_7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-031-61569-6_7","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5114226964","display_name":"J. Page","orcid":null},"institutions":[{"id":"https://openalex.org/I4210111757","display_name":"Rochester General Hospital","ror":"https://ror.org/01jk6xr82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210111757"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Jeffery Page","raw_affiliation_strings":["Center for Clinical Systems Biology, Rochester General Hospital, Rochester, NY, USA"],"affiliations":[{"raw_affiliation_string":"Center for Clinical Systems Biology, Rochester General Hospital, Rochester, NY, USA","institution_ids":["https://openalex.org/I4210111757"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089175484","display_name":"Kimberly A. Kelly","orcid":"https://orcid.org/0000-0002-1146-3137"},"institutions":[{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"funder","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]},{"id":"https://openalex.org/I198423848","display_name":"National Institute for Occupational Safety and Health","ror":"https://ror.org/0502a2655","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934","https://openalex.org/I198423848"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kimberly A. Kelly","raw_affiliation_strings":["Centers for Disease Control and Prevention, NIOSH, Morgantown, WV, USA"],"affiliations":[{"raw_affiliation_string":"Centers for Disease Control and Prevention, NIOSH, Morgantown, WV, USA","institution_ids":["https://openalex.org/I198423848","https://openalex.org/I1289490764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111167572","display_name":"Lindsay T. Michalovicz","orcid":null},"institutions":[{"id":"https://openalex.org/I198423848","display_name":"National Institute for Occupational Safety and Health","ror":"https://ror.org/0502a2655","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934","https://openalex.org/I198423848"]},{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"funder","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lindsay T. Michalovicz","raw_affiliation_strings":["Centers for Disease Control and Prevention, NIOSH, Morgantown, WV, USA"],"affiliations":[{"raw_affiliation_string":"Centers for Disease Control and Prevention, NIOSH, Morgantown, WV, USA","institution_ids":["https://openalex.org/I198423848","https://openalex.org/I1289490764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5098977874","display_name":"James P. O\u2019Callahghan","orcid":null},"institutions":[{"id":"https://openalex.org/I198423848","display_name":"National Institute for Occupational Safety and Health","ror":"https://ror.org/0502a2655","country_code":"US","type":"facility","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934","https://openalex.org/I198423848"]},{"id":"https://openalex.org/I1289490764","display_name":"Centers for Disease Control and Prevention","ror":"https://ror.org/042twtr12","country_code":"US","type":"funder","lineage":["https://openalex.org/I1289490764","https://openalex.org/I1299022934"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James P. O\u2019Callahghan","raw_affiliation_strings":["Centers for Disease Control and Prevention, NIOSH, Morgantown, WV, USA"],"affiliations":[{"raw_affiliation_string":"Centers for Disease Control and Prevention, NIOSH, Morgantown, WV, USA","institution_ids":["https://openalex.org/I198423848","https://openalex.org/I1289490764"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109402685","display_name":"Shichen Shen","orcid":null},"institutions":[{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shichen Shen","raw_affiliation_strings":["Department of Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA"],"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101494929","display_name":"Xiaoyu Zhu","orcid":"https://orcid.org/0000-0001-8466-9120"},"institutions":[{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaoyu Zhu","raw_affiliation_strings":["Department of Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA"],"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063759058","display_name":"Jun Qu","orcid":"https://orcid.org/0000-0002-1346-6809"},"institutions":[{"id":"https://openalex.org/I63190737","display_name":"University at Buffalo, State University of New York","ror":"https://ror.org/01y64my43","country_code":"US","type":"education","lineage":["https://openalex.org/I63190737"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jun Qu","raw_affiliation_strings":["Department of Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA"],"affiliations":[{"raw_affiliation_string":"Department of Pharmaceutical Sciences, University at Buffalo, Buffalo, NY, USA","institution_ids":["https://openalex.org/I63190737"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055857917","display_name":"Jonathan Boyd","orcid":"https://orcid.org/0000-0002-7023-9979"},"institutions":[{"id":"https://openalex.org/I184840846","display_name":"Virginia Commonwealth University","ror":"https://ror.org/02nkdxk79","country_code":"US","type":"education","lineage":["https://openalex.org/I184840846"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan Boyd","raw_affiliation_strings":["Department of Orthopaedic Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA, USA","institution_ids":["https://openalex.org/I184840846"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5015262975","display_name":"Gordon Broderick","orcid":"https://orcid.org/0000-0002-3588-8252"},"institutions":[{"id":"https://openalex.org/I4210111757","display_name":"Rochester General Hospital","ror":"https://ror.org/01jk6xr82","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210111757"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gordon Broderick","raw_affiliation_strings":["Center for Clinical Systems Biology, Rochester General Hospital, Rochester, NY, USA"],"affiliations":[{"raw_affiliation_string":"Center for Clinical Systems Biology, Rochester General Hospital, Rochester, NY, USA","institution_ids":["https://openalex.org/I4210111757"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":9,"corresponding_author_ids":["https://openalex.org/A5114226964"],"corresponding_institution_ids":["https://openalex.org/I4210111757"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.24547911,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"95","last_page":"110"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9884999990463257,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9884999990463257,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9668999910354614,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11303","display_name":"Bayesian Modeling and Causal Inference","score":0.92330002784729,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.8006561994552612},{"id":"https://openalex.org/keywords/constraint","display_name":"Constraint (computer-aided design)","score":0.6057714819908142},{"id":"https://openalex.org/keywords/constraint-satisfaction-problem","display_name":"Constraint satisfaction problem","score":0.5839086174964905},{"id":"https://openalex.org/keywords/constraint-satisfaction","display_name":"Constraint satisfaction","score":0.5627200603485107},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.30076444149017334},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.06832310557365417},{"id":"https://openalex.org/keywords/probabilistic-logic","display_name":"Probabilistic logic","score":0.05177748203277588}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.8006561994552612},{"id":"https://openalex.org/C2776036281","wikidata":"https://www.wikidata.org/wiki/Q48769818","display_name":"Constraint (computer-aided design)","level":2,"score":0.6057714819908142},{"id":"https://openalex.org/C199622910","wikidata":"https://www.wikidata.org/wiki/Q1128326","display_name":"Constraint satisfaction problem","level":3,"score":0.5839086174964905},{"id":"https://openalex.org/C44616089","wikidata":"https://www.wikidata.org/wiki/Q30158686","display_name":"Constraint satisfaction","level":3,"score":0.5627200603485107},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.30076444149017334},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.06832310557365417},{"id":"https://openalex.org/C49937458","wikidata":"https://www.wikidata.org/wiki/Q2599292","display_name":"Probabilistic logic","level":2,"score":0.05177748203277588},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-031-61569-6_7","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-031-61569-6_7","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1886819223","https://openalex.org/W1968877074","https://openalex.org/W1969856246","https://openalex.org/W1989284002","https://openalex.org/W1990043489","https://openalex.org/W1990521929","https://openalex.org/W2033215199","https://openalex.org/W2071141381","https://openalex.org/W2087983512","https://openalex.org/W2092947384","https://openalex.org/W2105597591","https://openalex.org/W2106947018","https://openalex.org/W2118185206","https://openalex.org/W2126877057","https://openalex.org/W2157989234","https://openalex.org/W2159875930","https://openalex.org/W2208500123","https://openalex.org/W2231507043","https://openalex.org/W2317856197","https://openalex.org/W2319494906","https://openalex.org/W2322294994","https://openalex.org/W2334039158","https://openalex.org/W2417344110","https://openalex.org/W2613979314","https://openalex.org/W2783487549","https://openalex.org/W2884325401","https://openalex.org/W2922816079","https://openalex.org/W2923424733","https://openalex.org/W3005884436","https://openalex.org/W3015125287","https://openalex.org/W3191866206","https://openalex.org/W3200853882","https://openalex.org/W3201957722","https://openalex.org/W4225927444","https://openalex.org/W7036823945"],"related_works":["https://openalex.org/W2161128834","https://openalex.org/W2091348864","https://openalex.org/W2569549435","https://openalex.org/W2097415053","https://openalex.org/W2012141606","https://openalex.org/W1550482496","https://openalex.org/W2784687883","https://openalex.org/W2102858635","https://openalex.org/W2012694101","https://openalex.org/W2470231588"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}