{"id":"https://openalex.org/W4323647241","doi":"https://doi.org/10.1007/978-3-031-25599-1_43","title":"Inferring Pathological Metabolic Patterns in Breast Cancer Tissue from Genome-Scale Models","display_name":"Inferring Pathological Metabolic Patterns in Breast Cancer Tissue from Genome-Scale Models","publication_year":2023,"publication_date":"2023-01-01","ids":{"openalex":"https://openalex.org/W4323647241","doi":"https://doi.org/10.1007/978-3-031-25599-1_43"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-031-25599-1_43","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-031-25599-1_43","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://bia.unibz.it/esploro/outputs/conferenceProceeding/Inferring-Pathological-Metabolic-Patterns-in-Breast/991006856891601241","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084921040","display_name":"Matteo N. Amaradio","orcid":"https://orcid.org/0000-0003-3942-4460"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Matteo N. Amaradio","raw_affiliation_strings":["Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058187503","display_name":"Giorgio Jansen","orcid":"https://orcid.org/0000-0001-7320-4053"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]},{"id":"https://openalex.org/I241749","display_name":"University of Cambridge","ror":"https://ror.org/013meh722","country_code":"GB","type":"education","lineage":["https://openalex.org/I241749"]}],"countries":["GB","IT"],"is_corresponding":false,"raw_author_name":"Giorgio Jansen","raw_affiliation_strings":["Department of Biochemistry, University of Cambridge, Cambridge, UK","Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Biochemistry, University of Cambridge, Cambridge, UK","institution_ids":["https://openalex.org/I241749"]},{"raw_affiliation_string":"Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058318377","display_name":"Varun Ojha","orcid":"https://orcid.org/0000-0002-9256-1192"},"institutions":[{"id":"https://openalex.org/I84884186","display_name":"Newcastle University","ror":"https://ror.org/01kj2bm70","country_code":"GB","type":"education","lineage":["https://openalex.org/I84884186"]},{"id":"https://openalex.org/I71052956","display_name":"University of Reading","ror":"https://ror.org/05v62cm79","country_code":"GB","type":"education","lineage":["https://openalex.org/I71052956"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Varun Ojha","raw_affiliation_strings":["School of Computing, Newcastle University, Newcastle Upon Tyne, UK","University of Reading, Reading, UK"],"affiliations":[{"raw_affiliation_string":"School of Computing, Newcastle University, Newcastle Upon Tyne, UK","institution_ids":["https://openalex.org/I84884186"]},{"raw_affiliation_string":"University of Reading, Reading, UK","institution_ids":["https://openalex.org/I71052956"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039973207","display_name":"Jole Costanza","orcid":"https://orcid.org/0000-0002-0290-3970"},"institutions":[{"id":"https://openalex.org/I4210160365","display_name":"Istituto Nazionale Genetica Molecolare","ror":"https://ror.org/05rb1q636","country_code":"IT","type":"nonprofit","lineage":["https://openalex.org/I4210160365"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Jole Costanza","raw_affiliation_strings":["Fondazione Instituto Nazionale Di Genetica Molecolare, Milan, Italy"],"affiliations":[{"raw_affiliation_string":"Fondazione Instituto Nazionale Di Genetica Molecolare, Milan, Italy","institution_ids":["https://openalex.org/I4210160365"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007549483","display_name":"Giuseppe Di Fatta","orcid":"https://orcid.org/0000-0003-3096-2844"},"institutions":[{"id":"https://openalex.org/I171543936","display_name":"Free University of Bozen-Bolzano","ror":"https://ror.org/012ajp527","country_code":"IT","type":"education","lineage":["https://openalex.org/I171543936"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Giuseppe Di Fatta","raw_affiliation_strings":["Free University of Bozen-Bolzano, Bolzano, Italy"],"affiliations":[{"raw_affiliation_string":"Free University of Bozen-Bolzano, Bolzano, Italy","institution_ids":["https://openalex.org/I171543936"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5026158192","display_name":"Giuseppe Nicosia","orcid":"https://orcid.org/0000-0002-0650-3157"},"institutions":[{"id":"https://openalex.org/I39063666","display_name":"University of Catania","ror":"https://ror.org/03a64bh57","country_code":"IT","type":"education","lineage":["https://openalex.org/I39063666"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Giuseppe Nicosia","raw_affiliation_strings":["Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy","University of Catania, Catania, Italy"],"affiliations":[{"raw_affiliation_string":"Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]},{"raw_affiliation_string":"University of Catania, Catania, Italy","institution_ids":["https://openalex.org/I39063666"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5026158192"],"corresponding_institution_ids":["https://openalex.org/I39063666"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":1.6875,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.82261177,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":95},"biblio":{"volume":null,"issue":null,"first_page":"596","last_page":"612"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9976999759674072,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10791","display_name":"Advanced Control Systems Optimization","score":0.9890000224113464,"subfield":{"id":"https://openalex.org/subfields/2207","display_name":"Control and Systems Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/in-silico","display_name":"In silico","score":0.7444023489952087},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.6224969625473022},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"Breast cancer","score":0.6147854924201965},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.5671089291572571},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5277517437934875},{"id":"https://openalex.org/keywords/human-genome","display_name":"Human genome","score":0.45670318603515625},{"id":"https://openalex.org/keywords/cancer","display_name":"Cancer","score":0.41922762989997864},{"id":"https://openalex.org/keywords/bioinformatics","display_name":"Bioinformatics","score":0.3349812924861908},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.32228702306747437},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.22641226649284363},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.22318023443222046}],"concepts":[{"id":"https://openalex.org/C2775905019","wikidata":"https://www.wikidata.org/wiki/Q192572","display_name":"In silico","level":3,"score":0.7444023489952087},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.6224969625473022},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.6147854924201965},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.5671089291572571},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5277517437934875},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.45670318603515625},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.41922762989997864},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3349812924861908},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.32228702306747437},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.22641226649284363},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.22318023443222046}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/978-3-031-25599-1_43","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-031-25599-1_43","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},{"id":"pmh:oai:unibz.it:11323825460001241","is_oa":true,"landing_page_url":"https://bia.unibz.it/esploro/outputs/conferenceProceeding/Inferring-Pathological-Metabolic-Patterns-in-Breast/991006856891601241","pdf_url":null,"source":{"id":"https://openalex.org/S4210197018","display_name":"View","issn_l":"2688-268X","issn":["2688-268X","2688-3988"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"}],"best_oa_location":{"id":"pmh:oai:unibz.it:11323825460001241","is_oa":true,"landing_page_url":"https://bia.unibz.it/esploro/outputs/conferenceProceeding/Inferring-Pathological-Metabolic-Patterns-in-Breast/991006856891601241","pdf_url":null,"source":{"id":"https://openalex.org/S4210197018","display_name":"View","issn_l":"2688-268X","issn":["2688-268X","2688-3988"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"},"sustainable_development_goals":[{"score":0.7799999713897705,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1482090313","https://openalex.org/W1576645054","https://openalex.org/W1619434176","https://openalex.org/W1753313258","https://openalex.org/W1926951007","https://openalex.org/W2010434645","https://openalex.org/W2046080114","https://openalex.org/W2062641936","https://openalex.org/W2078355959","https://openalex.org/W2127931938","https://openalex.org/W2131719921","https://openalex.org/W2202347610","https://openalex.org/W2801369487","https://openalex.org/W2916475656","https://openalex.org/W2943301094","https://openalex.org/W2945788288","https://openalex.org/W2987028578","https://openalex.org/W2995984012","https://openalex.org/W3003470753","https://openalex.org/W3023752815","https://openalex.org/W3048211865","https://openalex.org/W3092617690","https://openalex.org/W3122203348","https://openalex.org/W3197471843","https://openalex.org/W3206886897","https://openalex.org/W4210568616","https://openalex.org/W4224014712"],"related_works":["https://openalex.org/W4391375266","https://openalex.org/W3129816939","https://openalex.org/W2912862995","https://openalex.org/W2985427592","https://openalex.org/W2101501829","https://openalex.org/W2400569965","https://openalex.org/W2060263731","https://openalex.org/W2003194288","https://openalex.org/W1969895229","https://openalex.org/W2108497208"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}