{"id":"https://openalex.org/W4285172001","doi":"https://doi.org/10.1007/978-3-031-04749-7_3","title":"Transcription Factor-Centric Approach to Identify Non-recurring Putative Regulatory Drivers in Cancer","display_name":"Transcription Factor-Centric Approach to Identify Non-recurring Putative Regulatory Drivers in Cancer","publication_year":2022,"publication_date":"2022-01-01","ids":{"openalex":"https://openalex.org/W4285172001","doi":"https://doi.org/10.1007/978-3-031-04749-7_3","pmid":"https://pubmed.ncbi.nlm.nih.gov/36507923"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-031-04749-7_3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-031-04749-7_3","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9740185","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5102385742","display_name":"Jingkang Zhao","orcid":null},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jingkang Zhao","raw_affiliation_strings":["Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA","Program in Computational Biology and Bioinformatics, Duke University, Durham, NC 27708, USA","Center for Genomic and Computational Biology, Duke University, Durham, USA","Program in Computational Biology and Bioinformatics, Duke University, Durham, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Program in Computational Biology and Bioinformatics, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Center for Genomic and Computational Biology, Duke University, Durham, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Program in Computational Biology and Bioinformatics, Duke University, Durham, USA","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068262175","display_name":"Vincentius Martin","orcid":null},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vincentius Martin","raw_affiliation_strings":["Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA","Department of Computer Science, Duke University, Durham, NC 27708, USA","Center for Genomic and Computational Biology, Duke University, Durham, USA","Department of Computer Science, Duke University, Durham, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Department of Computer Science, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Center for Genomic and Computational Biology, Duke University, Durham, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Department of Computer Science, Duke University, Durham, USA","institution_ids":["https://openalex.org/I170897317"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5082030263","display_name":"Raluca Gord\u00e2n","orcid":"https://orcid.org/0000-0002-6404-6556"},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Raluca Gord\u00e2n","raw_affiliation_strings":["Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA","Department of Biostatistics and Bioinformatics, Duke University, Durham, NC 27708, USA","Department of Computer Science, Duke University, Durham, NC 27708, USA","Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27708, USA","Center for Genomic and Computational Biology, Duke University, Durham, USA","Department of Biostatistics and Bioinformatics, Duke University, Durham, USA","Department of Computer Science, Duke University, Durham, USA","Department of Molecular Genetics and Microbiology, Duke University, Durham, USA","Program in Computational Biology and Bioinformatics, Duke University, Durham, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genomic and Computational Biology, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Department of Biostatistics and Bioinformatics, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Department of Computer Science, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Department of Molecular Genetics and Microbiology, Duke University, Durham, NC 27708, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Center for Genomic and Computational Biology, Duke University, Durham, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Department of Biostatistics and Bioinformatics, Duke University, Durham, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Department of Computer Science, Duke University, Durham, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Department of Molecular Genetics and Microbiology, Duke University, Durham, USA","institution_ids":["https://openalex.org/I170897317"]},{"raw_affiliation_string":"Program in Computational Biology and Bioinformatics, Duke University, Durham, USA","institution_ids":["https://openalex.org/I170897317"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5082030263"],"corresponding_institution_ids":["https://openalex.org/I170897317"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":1.7317,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.85176471,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"13278","issue":null,"first_page":"36","last_page":"51"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.9998999834060669,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11642","display_name":"Genomics and Rare Diseases","score":0.9957000017166138,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.7059044241905212},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.626607358455658},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.6233479976654053},{"id":"https://openalex.org/keywords/regulatory-sequence","display_name":"Regulatory sequence","score":0.5977110862731934},{"id":"https://openalex.org/keywords/transcription-factor","display_name":"Transcription factor","score":0.5340344905853271},{"id":"https://openalex.org/keywords/somatic-cell","display_name":"Somatic cell","score":0.5282691717147827},{"id":"https://openalex.org/keywords/coding-region","display_name":"Coding region","score":0.49755170941352844},{"id":"https://openalex.org/keywords/mutation","display_name":"Mutation","score":0.495884507894516},{"id":"https://openalex.org/keywords/germline-mutation","display_name":"Germline mutation","score":0.47116929292678833},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.4332579970359802},{"id":"https://openalex.org/keywords/genome","display_name":"Genome","score":0.42032191157341003}],"concepts":[{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.7059044241905212},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.626607358455658},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6233479976654053},{"id":"https://openalex.org/C21592294","wikidata":"https://www.wikidata.org/wiki/Q3238407","display_name":"Regulatory sequence","level":4,"score":0.5977110862731934},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.5340344905853271},{"id":"https://openalex.org/C134305767","wikidata":"https://www.wikidata.org/wiki/Q725508","display_name":"Somatic cell","level":3,"score":0.5282691717147827},{"id":"https://openalex.org/C91779695","wikidata":"https://www.wikidata.org/wiki/Q3780824","display_name":"Coding region","level":3,"score":0.49755170941352844},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.495884507894516},{"id":"https://openalex.org/C13514818","wikidata":"https://www.wikidata.org/wiki/Q5552256","display_name":"Germline mutation","level":4,"score":0.47116929292678833},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4332579970359802},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.42032191157341003}],"mesh":[],"locations_count":3,"locations":[{"id":"doi:10.1007/978-3-031-04749-7_3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-031-04749-7_3","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},{"id":"pmid:36507923","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/36507923","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Research in computational molecular biology : ... Annual International Conference, RECOMB ... : proceedings. RECOMB (Conference : 2005- )","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:9740185","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9740185","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Res Comput Mol Biol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:9740185","is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/9740185","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Res Comput Mol Biol","raw_type":"Text"},"sustainable_development_goals":[{"score":0.6100000143051147,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"awards":[{"id":"https://openalex.org/G281885895","display_name":null,"funder_award_id":"R01 GM135658","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":43,"referenced_works":["https://openalex.org/W1547212375","https://openalex.org/W1587447328","https://openalex.org/W1882772761","https://openalex.org/W1971816489","https://openalex.org/W1975177444","https://openalex.org/W1995837988","https://openalex.org/W2009720434","https://openalex.org/W2014677321","https://openalex.org/W2015845481","https://openalex.org/W2030209169","https://openalex.org/W2085363874","https://openalex.org/W2104500293","https://openalex.org/W2108797218","https://openalex.org/W2111378135","https://openalex.org/W2114031931","https://openalex.org/W2115012618","https://openalex.org/W2173732482","https://openalex.org/W2270152626","https://openalex.org/W2271238666","https://openalex.org/W2278526634","https://openalex.org/W2341025815","https://openalex.org/W2346937970","https://openalex.org/W2606776638","https://openalex.org/W2724543993","https://openalex.org/W2724571272","https://openalex.org/W2737838117","https://openalex.org/W2749613778","https://openalex.org/W2767680469","https://openalex.org/W2805175436","https://openalex.org/W2944181739","https://openalex.org/W2945144872","https://openalex.org/W2956135855","https://openalex.org/W2976640061","https://openalex.org/W3004480399","https://openalex.org/W3004859565","https://openalex.org/W3006500278","https://openalex.org/W3042334589","https://openalex.org/W3047143891","https://openalex.org/W3094409093","https://openalex.org/W3096568637","https://openalex.org/W3108342587","https://openalex.org/W3182973519","https://openalex.org/W4230174249"],"related_works":["https://openalex.org/W4296060409","https://openalex.org/W3111064715","https://openalex.org/W2623784472","https://openalex.org/W1972248466","https://openalex.org/W2041452721","https://openalex.org/W824391999","https://openalex.org/W2065180810","https://openalex.org/W2940468410","https://openalex.org/W2054270613","https://openalex.org/W4200456173"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1}],"updated_date":"2026-08-21T09:56:20.448147","created_date":"2025-10-10T00:00:00"}