{"id":"https://openalex.org/W3111870226","doi":"https://doi.org/10.1007/978-3-030-64511-3_5","title":"Activation vs. Organization: Prognostic Implications of T and B Cell Features of the PDAC Microenvironment","display_name":"Activation vs. Organization: Prognostic Implications of T and B Cell Features of the PDAC Microenvironment","publication_year":2020,"publication_date":"2020-01-01","ids":{"openalex":"https://openalex.org/W3111870226","doi":"https://doi.org/10.1007/978-3-030-64511-3_5","mag":"3111870226"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-030-64511-3_5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-030-64511-3_5","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046257833","display_name":"Elliot Gray","orcid":"https://orcid.org/0000-0001-9894-3135"},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Elliot Gray","raw_affiliation_strings":["Computational Biology and Department of Biomedical Engineering, Oregon Health and Science University (OHSU), Portland, OR, USA"],"affiliations":[{"raw_affiliation_string":"Computational Biology and Department of Biomedical Engineering, Oregon Health and Science University (OHSU), Portland, OR, USA","institution_ids":["https://openalex.org/I165690674"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052117035","display_name":"Shannon M. Liudahl","orcid":"https://orcid.org/0000-0002-8587-8204"},"institutions":[{"id":"https://openalex.org/I71578702","display_name":"University of Portland","ror":"https://ror.org/01q6pmm96","country_code":"US","type":"education","lineage":["https://openalex.org/I71578702"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shannon Liudahl","raw_affiliation_strings":["Department of Cell, Developmental, and Cancer Biology, OHSU, Portland, OR, USA"],"affiliations":[{"raw_affiliation_string":"Department of Cell, Developmental, and Cancer Biology, OHSU, Portland, OR, USA","institution_ids":["https://openalex.org/I71578702"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086280484","display_name":"Shamilene Sivagnanam","orcid":"https://orcid.org/0000-0001-5966-1522"},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]},{"id":"https://openalex.org/I71578702","display_name":"University of Portland","ror":"https://ror.org/01q6pmm96","country_code":"US","type":"education","lineage":["https://openalex.org/I71578702"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shamilene Sivagnanam","raw_affiliation_strings":["Computational Biology and Department of Biomedical Engineering, Oregon Health and Science University (OHSU), Portland, OR, USA","Department of Cell, Developmental, and Cancer Biology, OHSU, Portland, OR, USA"],"affiliations":[{"raw_affiliation_string":"Computational Biology and Department of Biomedical Engineering, Oregon Health and Science University (OHSU), Portland, OR, USA","institution_ids":["https://openalex.org/I165690674"]},{"raw_affiliation_string":"Department of Cell, Developmental, and Cancer Biology, OHSU, Portland, OR, USA","institution_ids":["https://openalex.org/I71578702"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091700539","display_name":"Courtney B. Betts","orcid":"https://orcid.org/0000-0002-0432-0445"},"institutions":[{"id":"https://openalex.org/I71578702","display_name":"University of Portland","ror":"https://ror.org/01q6pmm96","country_code":"US","type":"education","lineage":["https://openalex.org/I71578702"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Courtney Betts","raw_affiliation_strings":["Department of Cell, Developmental, and Cancer Biology, OHSU, Portland, OR, USA"],"affiliations":[{"raw_affiliation_string":"Department of Cell, Developmental, and Cancer Biology, OHSU, Portland, OR, USA","institution_ids":["https://openalex.org/I71578702"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030632046","display_name":"Jason M. Link","orcid":"https://orcid.org/0000-0002-6892-0431"},"institutions":[{"id":"https://openalex.org/I71578702","display_name":"University of Portland","ror":"https://ror.org/01q6pmm96","country_code":"US","type":"education","lineage":["https://openalex.org/I71578702"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason Link","raw_affiliation_strings":["Brenden-Colson Center for Pancreatic Care, Portland, OR, USA","Department of Molecular and Medical Genetics, OHSU, Portland, OR, USA"],"affiliations":[{"raw_affiliation_string":"Brenden-Colson Center for Pancreatic Care, Portland, OR, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Molecular and Medical Genetics, OHSU, Portland, OR, USA","institution_ids":["https://openalex.org/I71578702"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085268206","display_name":"Dove Keith","orcid":"https://orcid.org/0000-0001-6104-3264"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dove Keith","raw_affiliation_strings":["Brenden-Colson Center for Pancreatic Care, Portland, OR, USA"],"affiliations":[{"raw_affiliation_string":"Brenden-Colson Center for Pancreatic Care, Portland, OR, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043127162","display_name":"Brett C. Sheppard","orcid":"https://orcid.org/0000-0002-2182-7547"},"institutions":[{"id":"https://openalex.org/I71578702","display_name":"University of Portland","ror":"https://ror.org/01q6pmm96","country_code":"US","type":"education","lineage":["https://openalex.org/I71578702"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brett Sheppard","raw_affiliation_strings":["Brenden-Colson Center for Pancreatic Care, Portland, OR, USA","Department of Surgery, OHSU, Portland, OR, USA"],"affiliations":[{"raw_affiliation_string":"Brenden-Colson Center for Pancreatic Care, Portland, OR, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Surgery, OHSU, Portland, OR, USA","institution_ids":["https://openalex.org/I71578702"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081536984","display_name":"Rosalie C. Sears","orcid":"https://orcid.org/0000-0003-1558-2413"},"institutions":[{"id":"https://openalex.org/I4390039369","display_name":"OHSU Knight Cancer Institute","ror":"https://ror.org/002shna07","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I165690674","https://openalex.org/I4390039369"]},{"id":"https://openalex.org/I71578702","display_name":"University of Portland","ror":"https://ror.org/01q6pmm96","country_code":"US","type":"education","lineage":["https://openalex.org/I71578702"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rosalie Sears","raw_affiliation_strings":["Brenden-Colson Center for Pancreatic Care, Portland, OR, USA","Department of Molecular and Medical Genetics, OHSU, Portland, OR, USA","Knight Cancer Institute, Portland, OR, USA"],"affiliations":[{"raw_affiliation_string":"Brenden-Colson Center for Pancreatic Care, Portland, OR, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Molecular and Medical Genetics, OHSU, Portland, OR, USA","institution_ids":["https://openalex.org/I71578702"]},{"raw_affiliation_string":"Knight Cancer Institute, Portland, OR, USA","institution_ids":["https://openalex.org/I4390039369"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013518150","display_name":"Guillaume Thibault","orcid":"https://orcid.org/0000-0002-0734-2041"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Guillaume Thibault","raw_affiliation_strings":["OHSU Center for Spatial Systems Biomedicine, Portland, OR, USA"],"affiliations":[{"raw_affiliation_string":"OHSU Center for Spatial Systems Biomedicine, Portland, OR, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028899187","display_name":"Joe W. Gray","orcid":"https://orcid.org/0000-0001-9225-6756"},"institutions":[{"id":"https://openalex.org/I4390039369","display_name":"OHSU Knight Cancer Institute","ror":"https://ror.org/002shna07","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I165690674","https://openalex.org/I4390039369"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joe W. Gray","raw_affiliation_strings":["Knight Cancer Institute, Portland, OR, USA","OHSU Center for Spatial Systems Biomedicine, Portland, OR, USA"],"affiliations":[{"raw_affiliation_string":"Knight Cancer Institute, Portland, OR, USA","institution_ids":["https://openalex.org/I4390039369"]},{"raw_affiliation_string":"OHSU Center for Spatial Systems Biomedicine, Portland, OR, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025353193","display_name":"Lisa M. Coussens","orcid":"https://orcid.org/0000-0003-2389-1865"},"institutions":[{"id":"https://openalex.org/I4390039369","display_name":"OHSU Knight Cancer Institute","ror":"https://ror.org/002shna07","country_code":null,"type":"healthcare","lineage":["https://openalex.org/I165690674","https://openalex.org/I4390039369"]},{"id":"https://openalex.org/I71578702","display_name":"University of Portland","ror":"https://ror.org/01q6pmm96","country_code":"US","type":"education","lineage":["https://openalex.org/I71578702"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa M. Coussens","raw_affiliation_strings":["Brenden-Colson Center for Pancreatic Care, Portland, OR, USA","Department of Cell, Developmental, and Cancer Biology, OHSU, Portland, OR, USA","Knight Cancer Institute, Portland, OR, USA"],"affiliations":[{"raw_affiliation_string":"Brenden-Colson Center for Pancreatic Care, Portland, OR, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Cell, Developmental, and Cancer Biology, OHSU, Portland, OR, USA","institution_ids":["https://openalex.org/I71578702"]},{"raw_affiliation_string":"Knight Cancer Institute, Portland, OR, USA","institution_ids":["https://openalex.org/I4390039369"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5003286550","display_name":"Young Hwan Chang","orcid":"https://orcid.org/0000-0001-8764-1959"},"institutions":[{"id":"https://openalex.org/I165690674","display_name":"Oregon Health & Science University","ror":"https://ror.org/009avj582","country_code":"US","type":"education","lineage":["https://openalex.org/I165690674"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Young Hwan Chang","raw_affiliation_strings":["Computational Biology and Department of Biomedical Engineering, Oregon Health and Science University (OHSU), Portland, OR, USA","OHSU Center for Spatial Systems Biomedicine, Portland, OR, USA"],"affiliations":[{"raw_affiliation_string":"Computational Biology and Department of Biomedical Engineering, Oregon Health and Science University (OHSU), Portland, OR, USA","institution_ids":["https://openalex.org/I165690674"]},{"raw_affiliation_string":"OHSU Center for Spatial Systems Biomedicine, Portland, OR, USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":12,"corresponding_author_ids":["https://openalex.org/A5046257833"],"corresponding_institution_ids":["https://openalex.org/I165690674"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.32225264,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"44","last_page":"55"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.9994000196456909,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.9987000226974487,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cd8","display_name":"CD8","score":0.6200630068778992},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"Tumor microenvironment","score":0.6125328540802002},{"id":"https://openalex.org/keywords/immune-system","display_name":"Immune system","score":0.5598341226577759},{"id":"https://openalex.org/keywords/granzyme-b","display_name":"Granzyme B","score":0.4803275167942047},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.464947372674942},{"id":"https://openalex.org/keywords/cancer-research","display_name":"Cancer research","score":0.38639843463897705},{"id":"https://openalex.org/keywords/oncology","display_name":"Oncology","score":0.33603161573410034},{"id":"https://openalex.org/keywords/immunology","display_name":"Immunology","score":0.32714560627937317},{"id":"https://openalex.org/keywords/internal-medicine","display_name":"Internal medicine","score":0.3260102868080139}],"concepts":[{"id":"https://openalex.org/C167672396","wikidata":"https://www.wikidata.org/wiki/Q417800","display_name":"CD8","level":3,"score":0.6200630068778992},{"id":"https://openalex.org/C2776107976","wikidata":"https://www.wikidata.org/wiki/Q1786433","display_name":"Tumor microenvironment","level":3,"score":0.6125328540802002},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5598341226577759},{"id":"https://openalex.org/C2780380082","wikidata":"https://www.wikidata.org/wiki/Q12646460","display_name":"Granzyme B","level":4,"score":0.4803275167942047},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.464947372674942},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.38639843463897705},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.33603161573410034},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.32714560627937317},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3260102868080139}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-3-030-64511-3_5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-030-64511-3_5","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.699999988079071}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":24,"referenced_works":["https://openalex.org/W1554400778","https://openalex.org/W1877687928","https://openalex.org/W2023003954","https://openalex.org/W2056132907","https://openalex.org/W2067509761","https://openalex.org/W2071462987","https://openalex.org/W2122825543","https://openalex.org/W2136964874","https://openalex.org/W2143426320","https://openalex.org/W2169410102","https://openalex.org/W2235361305","https://openalex.org/W2604591951","https://openalex.org/W2609921003","https://openalex.org/W2737082469","https://openalex.org/W2801309958","https://openalex.org/W2889115331","https://openalex.org/W2911964244","https://openalex.org/W2949238013","https://openalex.org/W2952001837","https://openalex.org/W2999681746","https://openalex.org/W3000311037","https://openalex.org/W3001603296","https://openalex.org/W3134530972","https://openalex.org/W4211181525"],"related_works":["https://openalex.org/W2362732960","https://openalex.org/W3149028178","https://openalex.org/W2084341973","https://openalex.org/W2364467823","https://openalex.org/W2062137773","https://openalex.org/W2382799725","https://openalex.org/W150405246","https://openalex.org/W2364025601","https://openalex.org/W4312061069","https://openalex.org/W2085382985"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
