{"id":"https://openalex.org/W32587957","doi":"https://doi.org/10.1007/978-3-030-32281-6_1","title":"ISOTOPIC EXCHANGE OF HYDROGEN IN HEXASUBSTITUTED BENZENE DERIVATIVES.","display_name":"ISOTOPIC EXCHANGE OF HYDROGEN IN HEXASUBSTITUTED BENZENE DERIVATIVES.","publication_year":1967,"publication_date":"1967-01-01","ids":{"openalex":"https://openalex.org/W32587957","doi":"https://doi.org/10.1007/978-3-030-32281-6_1","mag":"32587957"},"language":"en","primary_location":{"id":"mag:32587957","is_oa":false,"landing_page_url":"http://www.osti.gov/scitech/biblio/4774854-isotopic-exchange-hydrogen-hexasubstituted-benzene-derivatives","pdf_url":null,"source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PRedictive Intelligence in MEdicine. PRIME (Workshop)","raw_type":null},"type":"article","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110621713","display_name":"A. G. Ginzburg","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A. G. Ginzburg","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065419957","display_name":"V. N. Setkina","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V. N. Setkina","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5050378834","display_name":"D.N. Kursanov","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D.N. Kursanov","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.00378629,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"11843","issue":null,"first_page":"1","last_page":"10"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.5759000182151794,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.5759000182151794,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.04989999905228615,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments","score":0.02449999935925007,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/benzene","display_name":"Benzene","score":0.6789352893829346},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.6029518842697144},{"id":"https://openalex.org/keywords/hydrogen","display_name":"Hydrogen","score":0.43178704380989075},{"id":"https://openalex.org/keywords/medicinal-chemistry","display_name":"Medicinal chemistry","score":0.36662429571151733},{"id":"https://openalex.org/keywords/organic-chemistry","display_name":"Organic chemistry","score":0.30224084854125977}],"concepts":[{"id":"https://openalex.org/C2777691172","wikidata":"https://www.wikidata.org/wiki/Q2270","display_name":"Benzene","level":2,"score":0.6789352893829346},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6029518842697144},{"id":"https://openalex.org/C512968161","wikidata":"https://www.wikidata.org/wiki/Q556","display_name":"Hydrogen","level":2,"score":0.43178704380989075},{"id":"https://openalex.org/C155647269","wikidata":"https://www.wikidata.org/wiki/Q243455","display_name":"Medicinal chemistry","level":1,"score":0.36662429571151733},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.30224084854125977}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:32587957","is_oa":false,"landing_page_url":"http://www.osti.gov/scitech/biblio/4774854-isotopic-exchange-hydrogen-hexasubstituted-benzene-derivatives","pdf_url":null,"source":{"id":"https://openalex.org/S4306402487","display_name":"OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I139351228","host_organization_name":"Office of Scientific and Technical Information","host_organization_lineage":["https://openalex.org/I139351228"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"PRedictive Intelligence in MEdicine. PRIME (Workshop)","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G1131972899","display_name":null,"funder_award_id":"U01 AG024904","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G137498894","display_name":null,"funder_award_id":"P50 AG005142","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G337388051","display_name":null,"funder_award_id":"R01 NS086905","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G854044502","display_name":null,"funder_award_id":"P41 EB015902","funder_id":"https://openalex.org/F4320337363","funder_display_name":"National Institute of Biomedical Imaging and Bioengineering"}],"funders":[{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337363","display_name":"National Institute of Biomedical Imaging and Bioengineering","ror":"https://ror.org/00372qc85"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W286420790","https://openalex.org/W1976308335","https://openalex.org/W2063480972","https://openalex.org/W207660275","https://openalex.org/W34997643","https://openalex.org/W1980253720","https://openalex.org/W2054111148","https://openalex.org/W2007168805","https://openalex.org/W271801756","https://openalex.org/W2272335791","https://openalex.org/W2989525667","https://openalex.org/W2072378248","https://openalex.org/W2047081597","https://openalex.org/W1977672173","https://openalex.org/W323289933","https://openalex.org/W2066306107","https://openalex.org/W2024351013","https://openalex.org/W1970008898","https://openalex.org/W1966017211","https://openalex.org/W2051628038"],"abstract_inverted_index":{"The":[0,124,291],"Alzheimer's":[1,24,39,62,280],"Disease":[2,40,63],"Prediction":[3],"Of":[4],"Longitudinal":[5],"Evolution":[6],"(TADPOLE)":[7],"Challenge":[8,27],"compares":[9],"the":[10,16,38,74,87,91,98,111,162,165,190,206,216,252,263,297],"performance":[11],"of":[12,19,23,52,73,86,100,114,127,164,174,210,236,238],"algorithms":[13,33,275],"at":[14,21,97,182],"predicting":[15,183],"future":[17,82],"evolution":[18],"individuals":[20],"risk":[22],"disease.":[25],"TADPOLE":[26,128],"participants":[28,261],"train":[29],"their":[30],"models":[31],"and":[32,70,106,151,229,274,283],"on":[34,110,198,225],"historical":[35],"data":[36,93,137],"from":[37,144],"Neuroimaging":[41],"Initiative":[42],"(ADNI)":[43],"study.":[44],"Participants":[45],"are":[46,78,89,276],"then":[47,79,136],"required":[48],"to":[49,260],"make":[50],"forecasts":[51],"three":[53,185],"key":[54],"outcomes":[55],"for":[56,117,161,213,279,284],"ADNI-3":[57],"rollover":[58],"participants:":[59],"clinical":[60,118,149,289],"diagnosis,":[61],"Assessment":[64],"Scale":[65],"Cognitive":[66],"Subdomain":[67],"(ADAS-Cog":[68],"13),":[69],"total":[71,173,239],"volume":[72,241],"ventricles":[75],"-":[76],"which":[77,158,195,222,271],"compared":[80],"with":[81,147,171],"measurements.":[83],"Strong":[84],"points":[85],"challenge":[88],"that":[90,107],"test":[92],"did":[94],"not":[95],"exist":[96],"time":[99],"forecasting":[101],"(it":[102],"was":[103,129,159,180,196,223,248],"acquired":[104,140],"afterwards),":[105],"it":[108],"focuses":[109],"challenging":[112],"problem":[113],"cohort":[115],"selection":[116],"trials":[119],"by":[120],"identifying":[121],"fast":[122],"progressors.":[123],"submission":[125,179,264,292],"phase":[126],"open":[130,295],"until":[131,141],"15":[132],"November":[133],"2017;":[134],"since":[135],"has":[138],"been":[139],"April":[142],"2019":[143],"219":[145],"subjects":[146],"223":[148],"visits":[150],"150":[152],"Magnetic":[153],"Resonance":[154],"Imaging":[155],"(MRI)":[156],"scans,":[157],"used":[160],"evaluation":[163],"participants'":[166],"predictions.":[167],"Thirty-three":[168],"teams":[169],"participated":[170],"a":[172,202],"92":[175],"submissions.":[176],"No":[177],"single":[178],"best":[181,191,217],"all":[184],"outcomes.":[186],"For":[187,243],"diagnosis":[188],"prediction,":[189],"forecast":[192,218,247],"(team":[193,219],"Frog),":[194],"based":[197,224],"gradient":[199],"boosting,":[200],"obtained":[201,232],"multiclass":[203],"area":[204],"under":[205],"receiver-operating":[207],"curve":[208],"(MAUC)":[209],"0.931,":[211],"while":[212],"ventricle":[214],"prediction":[215,282],"<i>EMC1</i>":[220],"),":[221,258],"disease":[226,281],"progression":[227],"modelling":[228],"spline":[230],"regression,":[231],"mean":[233],"absolute":[234],"error":[235],"0.41%":[237],"intracranial":[240],"(ICV).":[242],"ADAS-Cog":[244],"13,":[245],"no":[246],"considerably":[249],"better":[250],"than":[251],"benchmark":[253],"mixed":[254],"effects":[255],"model":[256],"(<i>BenchmarkME</i>":[257],"provided":[259],"before":[262],"deadline.":[265],"Further":[266],"analysis":[267],"can":[268],"help":[269],"understand":[270],"input":[272],"features":[273],"most":[277],"suitable":[278],"aiding":[285],"patient":[286],"stratification":[287],"in":[288],"trials.":[290],"system":[293],"remains":[294],"via":[296],"website:":[298],"https://tadpole.grand-challenge.org/.":[299]},"counts_by_year":[],"updated_date":"2026-06-24T13:16:06.693445","created_date":"2016-06-24T00:00:00"}