{"id":"https://openalex.org/W2949905412","doi":"https://doi.org/10.1007/978-3-030-17297-8_15","title":"Towards the Integration of Metabolic Network Modelling and Machine Learning for the Routine Analysis of High-Throughput Patient Data","display_name":"Towards the Integration of Metabolic Network Modelling and Machine Learning for the Routine Analysis of High-Throughput Patient Data","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2949905412","doi":"https://doi.org/10.1007/978-3-030-17297-8_15","mag":"2949905412"},"language":"en","primary_location":{"id":"doi:10.1007/978-3-030-17297-8_15","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-030-17297-8_15","pdf_url":null,"source":{"id":"https://openalex.org/S4210239436","display_name":"Computational biology","issn_l":"1568-2684","issn":["1568-2684","2662-2432"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320108","host_organization_name":"Springer Nature (Netherlands)","host_organization_lineage":["https://openalex.org/P4310320108","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature (Netherlands)","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational Biology","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022936776","display_name":"Maria Pires Pacheco","orcid":"https://orcid.org/0000-0001-7956-8093"},"institutions":[{"id":"https://openalex.org/I186903577","display_name":"University of Luxembourg","ror":"https://ror.org/036x5ad56","country_code":"LU","type":"education","lineage":["https://openalex.org/I186903577"]}],"countries":["LU"],"is_corresponding":true,"raw_author_name":"Maria Pires Pacheco","raw_affiliation_strings":["University of Luxembourg, Luxembourg City, Luxembourg"],"affiliations":[{"raw_affiliation_string":"University of Luxembourg, Luxembourg City, Luxembourg","institution_ids":["https://openalex.org/I186903577"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005845910","display_name":"Tamara Bintener","orcid":"https://orcid.org/0000-0001-8218-666X"},"institutions":[{"id":"https://openalex.org/I186903577","display_name":"University of Luxembourg","ror":"https://ror.org/036x5ad56","country_code":"LU","type":"education","lineage":["https://openalex.org/I186903577"]}],"countries":["LU"],"is_corresponding":false,"raw_author_name":"Tamara Bintener","raw_affiliation_strings":["University of Luxembourg, Luxembourg City, Luxembourg"],"affiliations":[{"raw_affiliation_string":"University of Luxembourg, Luxembourg City, Luxembourg","institution_ids":["https://openalex.org/I186903577"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050871083","display_name":"Thomas Sauter","orcid":"https://orcid.org/0000-0001-8225-2954"},"institutions":[{"id":"https://openalex.org/I186903577","display_name":"University of Luxembourg","ror":"https://ror.org/036x5ad56","country_code":"LU","type":"education","lineage":["https://openalex.org/I186903577"]}],"countries":["LU"],"is_corresponding":false,"raw_author_name":"Thomas Sauter","raw_affiliation_strings":["University of Luxembourg, Luxembourg City, Luxembourg"],"affiliations":[{"raw_affiliation_string":"University of Luxembourg, Luxembourg City, Luxembourg","institution_ids":["https://openalex.org/I186903577"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5022936776"],"corresponding_institution_ids":["https://openalex.org/I186903577"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.09700862,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"401","last_page":"424"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10932","display_name":"Microbial Metabolic Engineering and Bioproduction","score":0.9998000264167786,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10887","display_name":"Bioinformatics and Genomic Networks","score":0.9993000030517578,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10836","display_name":"Metabolomics and Mass Spectrometry Studies","score":0.9878000020980835,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/workflow","display_name":"Workflow","score":0.7604128122329712},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7442209124565125},{"id":"https://openalex.org/keywords/bottleneck","display_name":"Bottleneck","score":0.7425030469894409},{"id":"https://openalex.org/keywords/context","display_name":"Context (archaeology)","score":0.656571626663208},{"id":"https://openalex.org/keywords/throughput","display_name":"Throughput","score":0.5865843296051025},{"id":"https://openalex.org/keywords/identification","display_name":"Identification (biology)","score":0.48721522092819214},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.456862211227417},{"id":"https://openalex.org/keywords/data-integration","display_name":"Data integration","score":0.417081356048584},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.40331920981407166},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.3915504515171051},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3650406002998352},{"id":"https://openalex.org/keywords/database","display_name":"Database","score":0.11362433433532715}],"concepts":[{"id":"https://openalex.org/C177212765","wikidata":"https://www.wikidata.org/wiki/Q627335","display_name":"Workflow","level":2,"score":0.7604128122329712},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7442209124565125},{"id":"https://openalex.org/C2780513914","wikidata":"https://www.wikidata.org/wiki/Q18210350","display_name":"Bottleneck","level":2,"score":0.7425030469894409},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.656571626663208},{"id":"https://openalex.org/C157764524","wikidata":"https://www.wikidata.org/wiki/Q1383412","display_name":"Throughput","level":3,"score":0.5865843296051025},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.48721522092819214},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.456862211227417},{"id":"https://openalex.org/C72634772","wikidata":"https://www.wikidata.org/wiki/Q386824","display_name":"Data integration","level":2,"score":0.417081356048584},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.40331920981407166},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.3915504515171051},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3650406002998352},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.11362433433532715},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0},{"id":"https://openalex.org/C149635348","wikidata":"https://www.wikidata.org/wiki/Q193040","display_name":"Embedded system","level":1,"score":0.0},{"id":"https://openalex.org/C555944384","wikidata":"https://www.wikidata.org/wiki/Q249","display_name":"Wireless","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1007/978-3-030-17297-8_15","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-3-030-17297-8_15","pdf_url":null,"source":{"id":"https://openalex.org/S4210239436","display_name":"Computational biology","issn_l":"1568-2684","issn":["1568-2684","2662-2432"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310320108","host_organization_name":"Springer Nature (Netherlands)","host_organization_lineage":["https://openalex.org/P4310320108","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature (Netherlands)","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Computational Biology","raw_type":"book-chapter"},{"id":"pmh:oai:orbilu.uni.lu:10993/39847","is_oa":false,"landing_page_url":"https://orbilu.uni.lu/handle/10993/39847","pdf_url":null,"source":{"id":"https://openalex.org/S4306401815","display_name":"Open Repository and Bibliography (University of Luxembourg)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I186903577","host_organization_name":"University of Luxembourg","host_organization_lineage":["https://openalex.org/I186903577"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Automated Reasoning for Systems Biology and Medicine. Springer (2019).","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/1","score":0.4699999988079071,"display_name":"No poverty"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":90,"referenced_works":["https://openalex.org/W53099289","https://openalex.org/W1505191356","https://openalex.org/W1528905581","https://openalex.org/W1823460074","https://openalex.org/W1873332500","https://openalex.org/W1895993106","https://openalex.org/W1934094702","https://openalex.org/W1934704664","https://openalex.org/W1967717472","https://openalex.org/W1969879564","https://openalex.org/W1973260880","https://openalex.org/W1976401385","https://openalex.org/W1976548998","https://openalex.org/W1982846895","https://openalex.org/W1984445372","https://openalex.org/W1989773675","https://openalex.org/W2001088234","https://openalex.org/W2003390994","https://openalex.org/W2005895632","https://openalex.org/W2005914550","https://openalex.org/W2009282793","https://openalex.org/W2011584557","https://openalex.org/W2011650177","https://openalex.org/W2043398720","https://openalex.org/W2044935306","https://openalex.org/W2045921664","https://openalex.org/W2047511535","https://openalex.org/W2058401000","https://openalex.org/W2061222476","https://openalex.org/W2067094344","https://openalex.org/W2072700707","https://openalex.org/W2073570060","https://openalex.org/W2076262841","https://openalex.org/W2078355959","https://openalex.org/W2097353028","https://openalex.org/W2099529347","https://openalex.org/W2099787654","https://openalex.org/W2102184039","https://openalex.org/W2104108767","https://openalex.org/W2106422137","https://openalex.org/W2108068107","https://openalex.org/W2111967267","https://openalex.org/W2122825543","https://openalex.org/W2124156743","https://openalex.org/W2128776645","https://openalex.org/W2131395804","https://openalex.org/W2132218677","https://openalex.org/W2134394193","https://openalex.org/W2134650984","https://openalex.org/W2137052779","https://openalex.org/W2137219016","https://openalex.org/W2138164217","https://openalex.org/W2142572836","https://openalex.org/W2144589197","https://openalex.org/W2152027903","https://openalex.org/W2152883907","https://openalex.org/W2156476088","https://openalex.org/W2158485828","https://openalex.org/W2158604980","https://openalex.org/W2162314899","https://openalex.org/W2162666840","https://openalex.org/W2166045336","https://openalex.org/W2171437346","https://openalex.org/W2171777347","https://openalex.org/W2172129062","https://openalex.org/W2180291937","https://openalex.org/W2264489059","https://openalex.org/W2272140989","https://openalex.org/W2274532218","https://openalex.org/W2285763735","https://openalex.org/W2291465340","https://openalex.org/W2306891483","https://openalex.org/W2461427403","https://openalex.org/W2487770199","https://openalex.org/W2555369234","https://openalex.org/W2564268887","https://openalex.org/W2597235951","https://openalex.org/W2603756957","https://openalex.org/W2609826536","https://openalex.org/W2745688516","https://openalex.org/W2765187412","https://openalex.org/W2768221398","https://openalex.org/W2769533087","https://openalex.org/W2771185483","https://openalex.org/W2771298068","https://openalex.org/W2773395161","https://openalex.org/W2790019331","https://openalex.org/W2944993265","https://openalex.org/W4236812392","https://openalex.org/W4294940931"],"related_works":["https://openalex.org/W2595172197","https://openalex.org/W2084856301","https://openalex.org/W2135248929","https://openalex.org/W2092690310","https://openalex.org/W1493624592","https://openalex.org/W3190662310","https://openalex.org/W1507878993","https://openalex.org/W2798440551","https://openalex.org/W2794767707","https://openalex.org/W2888459714"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}
