{"id":"https://openalex.org/W2417026128","doi":"https://doi.org/10.1007/978-1-60327-101-1_5","title":"Artificial Neural Network Modeling in Environmental Toxicology","display_name":"Artificial Neural Network Modeling in Environmental Toxicology","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W2417026128","doi":"https://doi.org/10.1007/978-1-60327-101-1_5","mag":"2417026128","pmid":"https://pubmed.ncbi.nlm.nih.gov/19065806"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-60327-101-1_5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-60327-101-1_5","pdf_url":null,"source":{"id":"https://openalex.org/S4210172139","display_name":"Methods in molecular biology","issn_l":"1064-3745","issn":["1064-3745","1940-6029"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Molecular Biology\u2122","raw_type":"book-chapter"},"type":"review","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5052200482","display_name":"James Devillers","orcid":null},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"James Devillers","raw_affiliation_strings":["CTIS, Rillieux La Pape, France"],"affiliations":[{"raw_affiliation_string":"CTIS, Rillieux La Pape, France","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5052200482"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.732,"has_fulltext":false,"cited_by_count":8,"citation_normalized_percentile":{"value":0.7153268,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"458","issue":null,"first_page":"59","last_page":"77"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9944000244140625,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T14249","display_name":"Water Quality Monitoring and Analysis","score":0.9923999905586243,"subfield":{"id":"https://openalex.org/subfields/2311","display_name":"Industrial and Manufacturing Engineering"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10640","display_name":"Spectroscopy and Chemometric Analyses","score":0.9822999835014343,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ecotoxicity","display_name":"Ecotoxicity","score":0.8687273263931274},{"id":"https://openalex.org/keywords/quantitative-structure\u2013activity-relationship","display_name":"Quantitative structure\u2013activity relationship","score":0.6779128909111023},{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.66412752866745},{"id":"https://openalex.org/keywords/environmental-toxicology","display_name":"Environmental toxicology","score":0.6536970734596252},{"id":"https://openalex.org/keywords/aquatic-toxicology","display_name":"Aquatic toxicology","score":0.5106509327888489},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4343460202217102},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.42368295788764954},{"id":"https://openalex.org/keywords/biochemical-engineering","display_name":"Biochemical engineering","score":0.3215521574020386},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.253047913312912},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.2151728868484497},{"id":"https://openalex.org/keywords/chemistry","display_name":"Chemistry","score":0.18926414847373962},{"id":"https://openalex.org/keywords/toxicity","display_name":"Toxicity","score":0.06545346975326538}],"concepts":[{"id":"https://openalex.org/C46797941","wikidata":"https://www.wikidata.org/wiki/Q5333900","display_name":"Ecotoxicity","level":3,"score":0.8687273263931274},{"id":"https://openalex.org/C164126121","wikidata":"https://www.wikidata.org/wiki/Q766383","display_name":"Quantitative structure\u2013activity relationship","level":2,"score":0.6779128909111023},{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.66412752866745},{"id":"https://openalex.org/C41157215","wikidata":"https://www.wikidata.org/wiki/Q3995923","display_name":"Environmental toxicology","level":3,"score":0.6536970734596252},{"id":"https://openalex.org/C8381438","wikidata":"https://www.wikidata.org/wiki/Q4117900","display_name":"Aquatic toxicology","level":3,"score":0.5106509327888489},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4343460202217102},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.42368295788764954},{"id":"https://openalex.org/C183696295","wikidata":"https://www.wikidata.org/wiki/Q2487696","display_name":"Biochemical engineering","level":1,"score":0.3215521574020386},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.253047913312912},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.2151728868484497},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.18926414847373962},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.06545346975326538},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001419","descriptor_name":"Bacteria","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002627","descriptor_name":"Chemistry, Physical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002627","descriptor_name":"Chemistry, Physical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D002627","descriptor_name":"Chemistry, Physical","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D003445","descriptor_name":"Crustacea","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003445","descriptor_name":"Crustacea","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003445","descriptor_name":"Crustacea","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004463","descriptor_name":"Ecology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004463","descriptor_name":"Ecology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004463","descriptor_name":"Ecology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004784","descriptor_name":"Environmental Monitoring","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004784","descriptor_name":"Environmental Monitoring","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D004784","descriptor_name":"Environmental Monitoring","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005399","descriptor_name":"Fishes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005399","descriptor_name":"Fishes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005399","descriptor_name":"Fishes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007313","descriptor_name":"Insecta","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007313","descriptor_name":"Insecta","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007313","descriptor_name":"Insecta","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015262","descriptor_name":"Xenobiotics","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015262","descriptor_name":"Xenobiotics","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015262","descriptor_name":"Xenobiotics","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016571","descriptor_name":"Neural Networks, Computer","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D017753","descriptor_name":"Ecosystem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017753","descriptor_name":"Ecosystem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017753","descriptor_name":"Ecosystem","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021281","descriptor_name":"Quantitative Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021281","descriptor_name":"Quantitative Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D021281","descriptor_name":"Quantitative Structure-Activity Relationship","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D054750","descriptor_name":"Ecotoxicology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D054750","descriptor_name":"Ecotoxicology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D054750","descriptor_name":"Ecotoxicology","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D056890","descriptor_name":"Eukaryota","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D056890","descriptor_name":"Eukaryota","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D056890","descriptor_name":"Eukaryota","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-1-60327-101-1_5","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-60327-101-1_5","pdf_url":null,"source":{"id":"https://openalex.org/S4210172139","display_name":"Methods in molecular biology","issn_l":"1064-3745","issn":["1064-3745","1940-6029"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Molecular Biology\u2122","raw_type":"book-chapter"},{"id":"pmid:19065806","is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19065806","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in molecular biology (Clifton, N.J.)","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Life in Land","score":0.6200000047683716,"id":"https://metadata.un.org/sdg/15"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":64,"referenced_works":["https://openalex.org/W124337703","https://openalex.org/W135375627","https://openalex.org/W563360778","https://openalex.org/W610608852","https://openalex.org/W612879516","https://openalex.org/W623814603","https://openalex.org/W655356045","https://openalex.org/W1409662939","https://openalex.org/W1498436455","https://openalex.org/W1516478776","https://openalex.org/W1563088657","https://openalex.org/W1567512734","https://openalex.org/W1575881144","https://openalex.org/W1595740553","https://openalex.org/W1895919974","https://openalex.org/W1963527575","https://openalex.org/W1970871633","https://openalex.org/W1983018026","https://openalex.org/W1983709984","https://openalex.org/W1984568490","https://openalex.org/W1988400995","https://openalex.org/W1988883946","https://openalex.org/W1990237101","https://openalex.org/W2001193543","https://openalex.org/W2007626613","https://openalex.org/W2007698848","https://openalex.org/W2014477059","https://openalex.org/W2015936411","https://openalex.org/W2022500222","https://openalex.org/W2023531582","https://openalex.org/W2024081693","https://openalex.org/W2027237537","https://openalex.org/W2030579744","https://openalex.org/W2030967055","https://openalex.org/W2044235819","https://openalex.org/W2058857490","https://openalex.org/W2060413154","https://openalex.org/W2062225960","https://openalex.org/W2063530812","https://openalex.org/W2066273940","https://openalex.org/W2066622013","https://openalex.org/W2067921518","https://openalex.org/W2072720531","https://openalex.org/W2076147571","https://openalex.org/W2091886411","https://openalex.org/W2100099385","https://openalex.org/W2102201073","https://openalex.org/W2108764346","https://openalex.org/W2123799684","https://openalex.org/W2123992881","https://openalex.org/W2135897723","https://openalex.org/W2160101329","https://openalex.org/W2170877187","https://openalex.org/W2504189326","https://openalex.org/W2592138671","https://openalex.org/W2728988083","https://openalex.org/W2797583072","https://openalex.org/W2898471783","https://openalex.org/W2920895311","https://openalex.org/W2922487361","https://openalex.org/W4240861491","https://openalex.org/W4243491992","https://openalex.org/W4249303080","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2900716511","https://openalex.org/W2622261847","https://openalex.org/W1992133913","https://openalex.org/W2734735927","https://openalex.org/W2753230657","https://openalex.org/W4319234512","https://openalex.org/W4318953392","https://openalex.org/W2038537919","https://openalex.org/W2510237741","https://openalex.org/W2056671160"],"abstract_inverted_index":{"Artificial":[0],"neural":[1],"networks":[2],"are":[3,58,65],"increasingly":[4],"used":[5],"in":[6],"environmental":[7],"toxicology":[8],"to":[9,34],"find":[10],"complex":[11],"relationships":[12],"between":[13],"the":[14,48],"ecotoxicity":[15],"of":[16,27,43],"xenobiotics":[17],"and":[18,55,62],"their":[19,32],"structure":[20],"and/or":[21],"physicochemical":[22],"properties.":[23],"The":[24],"raison":[25],"d'etre":[26],"these":[28],"nonlinear":[29],"tools":[30],"is":[31],"ability":[33],"derive":[35],"powerful":[36],"QSARs":[37],"for":[38,53],"molecules":[39],"presenting":[40],"different":[41],"mechanisms":[42],"action.":[44],"In":[45],"this":[46],"chapter,":[47],"main":[49],"QSAR":[50],"models":[51],"derived":[52],"aquatic":[54],"terrestrial":[56],"species":[57],"reviewed.":[59],"Their":[60],"characteristics":[61],"modeling":[63],"performances":[64],"deeply":[66],"analyzed.":[67]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2014,"cited_by_count":3}],"updated_date":"2026-01-13T01:12:25.745995","created_date":"2025-10-10T00:00:00"}