{"id":"https://openalex.org/W107152574","doi":"https://doi.org/10.1007/978-1-4471-0513-8_35","title":"A Hybrid Classification Tree and Artificial Neural Network Model for Predicting the In vitro Response of the Human Immunodeficiency Virus (HIV1) to Anti-Viral Drug Therapy","display_name":"A Hybrid Classification Tree and Artificial Neural Network Model for Predicting the In vitro Response of the Human Immunodeficiency Virus (HIV1) to Anti-Viral Drug Therapy","publication_year":2000,"publication_date":"2000-01-01","ids":{"openalex":"https://openalex.org/W107152574","doi":"https://doi.org/10.1007/978-1-4471-0513-8_35","mag":"107152574"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4471-0513-8_35","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4471-0513-8_35","pdf_url":null,"source":{"id":"https://openalex.org/S4210236473","display_name":"Perspectives in neural computing","issn_l":"1431-6854","issn":["1431-6854"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Perspectives in Neural Computing","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072758095","display_name":"Wayne R. Danter","orcid":"https://orcid.org/0000-0002-9297-4405"},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"W. R. Danter","raw_affiliation_strings":["Departments of Medicine, University of Western Ontario, London, Canada","University of Western Ontario"],"affiliations":[{"raw_affiliation_string":"Departments of Medicine, University of Western Ontario, London, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"University of Western Ontario","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057650327","display_name":"Daniel B. Gregson","orcid":"https://orcid.org/0000-0002-5677-5003"},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"D. Gregson","raw_affiliation_strings":["Departments of Medicine, University of Western Ontario, London, Canada","University of Western Ontario"],"affiliations":[{"raw_affiliation_string":"Departments of Medicine, University of Western Ontario, London, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"University of Western Ontario","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004888223","display_name":"Kristi J. Ferguson","orcid":"https://orcid.org/0000-0003-1605-0611"},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"K. A Ferguson","raw_affiliation_strings":["Departments of Medicine, University of Western Ontario, London, Canada","University of Western Ontario"],"affiliations":[{"raw_affiliation_string":"Departments of Medicine, University of Western Ontario, London, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"University of Western Ontario","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067334630","display_name":"Matthew Danter","orcid":"https://orcid.org/0000-0001-7758-8779"},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"M. R. Danter","raw_affiliation_strings":["Departments of Medicine, University of Western Ontario, London, Canada","University of Western Ontario"],"affiliations":[{"raw_affiliation_string":"Departments of Medicine, University of Western Ontario, London, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"University of Western Ontario","institution_ids":["https://openalex.org/I125749732"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112799049","display_name":"John R. Bend","orcid":null},"institutions":[{"id":"https://openalex.org/I125749732","display_name":"Western University","ror":"https://ror.org/02grkyz14","country_code":"CA","type":"education","lineage":["https://openalex.org/I125749732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"J. Bend","raw_affiliation_strings":["Pharmacology and Toxicology, University of Western Ontario, London, Canada","University of Western Ontario"],"affiliations":[{"raw_affiliation_string":"Pharmacology and Toxicology, University of Western Ontario, London, Canada","institution_ids":["https://openalex.org/I125749732"]},{"raw_affiliation_string":"University of Western Ontario","institution_ids":["https://openalex.org/I125749732"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5072758095"],"corresponding_institution_ids":["https://openalex.org/I125749732"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.04600326,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"235","last_page":"240"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9894000291824341,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.9843999743461609,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/artificial-neural-network","display_name":"Artificial neural network","score":0.7614297270774841},{"id":"https://openalex.org/keywords/cart","display_name":"Cart","score":0.6626404523849487},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.6159704923629761},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.512349009513855},{"id":"https://openalex.org/keywords/receiver-operating-characteristic","display_name":"Receiver operating characteristic","score":0.4604938328266144},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4466722011566162},{"id":"https://openalex.org/keywords/probabilistic-neural-network","display_name":"Probabilistic neural network","score":0.43389222025871277},{"id":"https://openalex.org/keywords/decision-tree","display_name":"Decision tree","score":0.4315205514431},{"id":"https://openalex.org/keywords/tree","display_name":"Tree (set theory)","score":0.4262264370918274},{"id":"https://openalex.org/keywords/biological-system","display_name":"Biological system","score":0.34862348437309265},{"id":"https://openalex.org/keywords/pattern-recognition","display_name":"Pattern recognition (psychology)","score":0.33997827768325806},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.33657485246658325},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.19793471693992615},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.1937863528728485},{"id":"https://openalex.org/keywords/engineering","display_name":"Engineering","score":0.1907968521118164},{"id":"https://openalex.org/keywords/time-delay-neural-network","display_name":"Time delay neural network","score":0.11659994721412659}],"concepts":[{"id":"https://openalex.org/C50644808","wikidata":"https://www.wikidata.org/wiki/Q192776","display_name":"Artificial neural network","level":2,"score":0.7614297270774841},{"id":"https://openalex.org/C2777275308","wikidata":"https://www.wikidata.org/wiki/Q234668","display_name":"Cart","level":2,"score":0.6626404523849487},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.6159704923629761},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.512349009513855},{"id":"https://openalex.org/C58471807","wikidata":"https://www.wikidata.org/wiki/Q327120","display_name":"Receiver operating characteristic","level":2,"score":0.4604938328266144},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4466722011566162},{"id":"https://openalex.org/C134342201","wikidata":"https://www.wikidata.org/wiki/Q7246859","display_name":"Probabilistic neural network","level":4,"score":0.43389222025871277},{"id":"https://openalex.org/C84525736","wikidata":"https://www.wikidata.org/wiki/Q831366","display_name":"Decision tree","level":2,"score":0.4315205514431},{"id":"https://openalex.org/C113174947","wikidata":"https://www.wikidata.org/wiki/Q2859736","display_name":"Tree (set theory)","level":2,"score":0.4262264370918274},{"id":"https://openalex.org/C186060115","wikidata":"https://www.wikidata.org/wiki/Q30336093","display_name":"Biological system","level":1,"score":0.34862348437309265},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.33997827768325806},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.33657485246658325},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.19793471693992615},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1937863528728485},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.1907968521118164},{"id":"https://openalex.org/C175202392","wikidata":"https://www.wikidata.org/wiki/Q2434543","display_name":"Time delay neural network","level":3,"score":0.11659994721412659},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4471-0513-8_35","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4471-0513-8_35","pdf_url":null,"source":{"id":"https://openalex.org/S4210236473","display_name":"Perspectives in neural computing","issn_l":"1431-6854","issn":["1431-6854"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Perspectives in Neural Computing","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8299999833106995,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W1489213086","https://openalex.org/W1597190145","https://openalex.org/W1976683819","https://openalex.org/W1993785915","https://openalex.org/W1998619885","https://openalex.org/W2010069697","https://openalex.org/W2013347800","https://openalex.org/W2039173155","https://openalex.org/W2096580895","https://openalex.org/W2123715374","https://openalex.org/W2140827333","https://openalex.org/W4244471710","https://openalex.org/W4298053142"],"related_works":["https://openalex.org/W4400093351","https://openalex.org/W3193909393","https://openalex.org/W2322350723","https://openalex.org/W2618011907","https://openalex.org/W4226229889","https://openalex.org/W2945144341","https://openalex.org/W2974098477","https://openalex.org/W3126687991","https://openalex.org/W2258783214","https://openalex.org/W4255564201"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}
