{"id":"https://openalex.org/W4396966111","doi":"https://doi.org/10.1007/978-1-0716-3989-4_52","title":"A Scalable Adaptive Quadratic Kernel Method for\u00a0Interpretable Epistasis Analysis in\u00a0Complex Traits","display_name":"A Scalable Adaptive Quadratic Kernel Method for\u00a0Interpretable Epistasis Analysis in\u00a0Complex Traits","publication_year":2024,"publication_date":"2024-01-01","ids":{"openalex":"https://openalex.org/W4396966111","doi":"https://doi.org/10.1007/978-1-0716-3989-4_52"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-0716-3989-4_52","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-0716-3989-4_52","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040850992","display_name":"Boyang Fu","orcid":"https://orcid.org/0000-0002-0082-8735"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Boyang Fu","raw_affiliation_strings":["Department of Computer Science, UCLA, Los Angeles, CA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, UCLA, Los Angeles, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101688843","display_name":"Prateek Anand","orcid":"https://orcid.org/0009-0004-8455-1308"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Prateek Anand","raw_affiliation_strings":["Department of Computer Science, UCLA, Los Angeles, CA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, UCLA, Los Angeles, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102740755","display_name":"Aakarsh Anand","orcid":null},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aakarsh Anand","raw_affiliation_strings":["Department of Computer Science, UCLA, Los Angeles, CA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computer Science, UCLA, Los Angeles, CA, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046956664","display_name":"Joel Mefford","orcid":"https://orcid.org/0000-0003-3036-545X"},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Joel Mefford","raw_affiliation_strings":["Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA"],"affiliations":[{"raw_affiliation_string":"Semel Institute for Neuroscience and Human Behavior, UCLA, Los Angeles, CA, USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049741676","display_name":"Sriram Sankararaman","orcid":"https://orcid.org/0000-0003-1586-9641"},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Sriram Sankararaman","raw_affiliation_strings":["Department of Computational Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA","Department of Computer Science, UCLA, Los Angeles, CA, USA","Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA"],"affiliations":[{"raw_affiliation_string":"Department of Computational Medicine, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Computer Science, UCLA, Los Angeles, CA, USA","institution_ids":[]},{"raw_affiliation_string":"Department of Human Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5049741676"],"corresponding_institution_ids":["https://openalex.org/I161318765"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":1.5274,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.77487167,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":90,"max":94},"biblio":{"volume":null,"issue":null,"first_page":"458","last_page":"461"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9057000279426575,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10885","display_name":"Gene expression and cancer classification","score":0.9057000279426575,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.7992558479309082},{"id":"https://openalex.org/keywords/epistasis","display_name":"Epistasis","score":0.7348287105560303},{"id":"https://openalex.org/keywords/scalability","display_name":"Scalability","score":0.6761113405227661},{"id":"https://openalex.org/keywords/kernel","display_name":"Kernel (algebra)","score":0.6218134164810181},{"id":"https://openalex.org/keywords/quadratic-equation","display_name":"Quadratic equation","score":0.5588109493255615},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4423469007015228},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.4305976331233978},{"id":"https://openalex.org/keywords/kernel-method","display_name":"Kernel method","score":0.42820024490356445},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.3419806957244873},{"id":"https://openalex.org/keywords/mathematics","display_name":"Mathematics","score":0.1618030071258545},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.11932483315467834},{"id":"https://openalex.org/keywords/discrete-mathematics","display_name":"Discrete mathematics","score":0.10221567749977112},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.06392934918403625}],"concepts":[{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.7992558479309082},{"id":"https://openalex.org/C61727976","wikidata":"https://www.wikidata.org/wiki/Q751748","display_name":"Epistasis","level":3,"score":0.7348287105560303},{"id":"https://openalex.org/C48044578","wikidata":"https://www.wikidata.org/wiki/Q727490","display_name":"Scalability","level":2,"score":0.6761113405227661},{"id":"https://openalex.org/C74193536","wikidata":"https://www.wikidata.org/wiki/Q574844","display_name":"Kernel (algebra)","level":2,"score":0.6218134164810181},{"id":"https://openalex.org/C129844170","wikidata":"https://www.wikidata.org/wiki/Q41299","display_name":"Quadratic equation","level":2,"score":0.5588109493255615},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4423469007015228},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.4305976331233978},{"id":"https://openalex.org/C122280245","wikidata":"https://www.wikidata.org/wiki/Q620622","display_name":"Kernel method","level":3,"score":0.42820024490356445},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.3419806957244873},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1618030071258545},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.11932483315467834},{"id":"https://openalex.org/C118615104","wikidata":"https://www.wikidata.org/wiki/Q121416","display_name":"Discrete mathematics","level":1,"score":0.10221567749977112},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.06392934918403625},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0},{"id":"https://openalex.org/C77088390","wikidata":"https://www.wikidata.org/wiki/Q8513","display_name":"Database","level":1,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-0716-3989-4_52","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-0716-3989-4_52","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":4,"referenced_works":["https://openalex.org/W1798697719","https://openalex.org/W2103019860","https://openalex.org/W3080999617","https://openalex.org/W4385839618"],"related_works":["https://openalex.org/W2089892314","https://openalex.org/W1603091392","https://openalex.org/W4386075310","https://openalex.org/W2169565408","https://openalex.org/W2127229869","https://openalex.org/W3123056048","https://openalex.org/W2150638158","https://openalex.org/W2121506664","https://openalex.org/W2363184354","https://openalex.org/W2137862631"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1}],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2025-10-10T00:00:00"}