{"id":"https://openalex.org/W1587845087","doi":"https://doi.org/10.1007/11905455_1","title":"Modelling the Influence of RKIP on the ERK Signalling Pathway Using the Stochastic Process Algebra PEPA","display_name":"Modelling the Influence of RKIP on the ERK Signalling Pathway Using the Stochastic Process Algebra PEPA","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W1587845087","doi":"https://doi.org/10.1007/11905455_1","mag":"1587845087"},"language":"en","primary_location":{"id":"doi:10.1007/11905455_1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/11905455_1","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.research.ed.ac.uk/en/publications/80b9a2c0-88aa-4387-85d1-feff7846bd19","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5015862123","display_name":"Muffy Calder","orcid":"https://orcid.org/0000-0001-5033-7232"},"institutions":[{"id":"https://openalex.org/I7882870","display_name":"University of Glasgow","ror":"https://ror.org/00vtgdb53","country_code":"GB","type":"education","lineage":["https://openalex.org/I7882870"]}],"countries":["GB"],"is_corresponding":true,"raw_author_name":"Muffy Calder","raw_affiliation_strings":["Department of Computing Science, The University of Glasgow, Glasgow, Scotland"],"affiliations":[{"raw_affiliation_string":"Department of Computing Science, The University of Glasgow, Glasgow, Scotland","institution_ids":["https://openalex.org/I7882870"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000114432","display_name":"Stephen Gilmore","orcid":"https://orcid.org/0000-0002-3657-989X"},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Stephen Gilmore","raw_affiliation_strings":["Laboratory for Foundations of Computer Science, The University of Edinburgh, Scotland"],"affiliations":[{"raw_affiliation_string":"Laboratory for Foundations of Computer Science, The University of Edinburgh, Scotland","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035860397","display_name":"Jane Hillston","orcid":"https://orcid.org/0000-0003-4914-9255"},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Jane Hillston","raw_affiliation_strings":["Laboratory for Foundations of Computer Science, The University of Edinburgh, Scotland"],"affiliations":[{"raw_affiliation_string":"Laboratory for Foundations of Computer Science, The University of Edinburgh, Scotland","institution_ids":["https://openalex.org/I98677209"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5015862123"],"corresponding_institution_ids":["https://openalex.org/I7882870"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":72.5003,"has_fulltext":false,"cited_by_count":211,"citation_normalized_percentile":{"value":0.99959393,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":null,"issue":null,"first_page":"1","last_page":"23"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10621","display_name":"Gene Regulatory Network Analysis","score":0.9991000294685364,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.9975000023841858,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10211","display_name":"Computational Drug Discovery Methods","score":0.9912999868392944,"subfield":{"id":"https://openalex.org/subfields/1703","display_name":"Computational Theory and Mathematics"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/process-calculus","display_name":"Process calculus","score":0.7952708005905151},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.6838602423667908},{"id":"https://openalex.org/keywords/mapk/erk-pathway","display_name":"MAPK/ERK pathway","score":0.555223286151886},{"id":"https://openalex.org/keywords/theoretical-computer-science","display_name":"Theoretical computer science","score":0.48370081186294556},{"id":"https://openalex.org/keywords/process","display_name":"Process (computing)","score":0.48047035932540894},{"id":"https://openalex.org/keywords/affordance","display_name":"Affordance","score":0.47753727436065674},{"id":"https://openalex.org/keywords/semantics","display_name":"Semantics (computer science)","score":0.4692378342151642},{"id":"https://openalex.org/keywords/bisimulation","display_name":"Bisimulation","score":0.45222264528274536},{"id":"https://openalex.org/keywords/signalling-pathways","display_name":"Signalling pathways","score":0.44823262095451355},{"id":"https://openalex.org/keywords/signalling","display_name":"Signalling","score":0.4227638840675354},{"id":"https://openalex.org/keywords/distributed-computing","display_name":"Distributed computing","score":0.38216283917427063},{"id":"https://openalex.org/keywords/kinase","display_name":"Kinase","score":0.36441856622695923},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.3254165053367615},{"id":"https://openalex.org/keywords/signal-transduction","display_name":"Signal transduction","score":0.25546011328697205},{"id":"https://openalex.org/keywords/programming-language","display_name":"Programming language","score":0.18241170048713684},{"id":"https://openalex.org/keywords/human\u2013computer-interaction","display_name":"Human\u2013computer interaction","score":0.11713835597038269},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.11575430631637573},{"id":"https://openalex.org/keywords/cell-biology","display_name":"Cell biology","score":0.10872092843055725}],"concepts":[{"id":"https://openalex.org/C161771561","wikidata":"https://www.wikidata.org/wiki/Q1970286","display_name":"Process calculus","level":2,"score":0.7952708005905151},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.6838602423667908},{"id":"https://openalex.org/C57074206","wikidata":"https://www.wikidata.org/wiki/Q14197552","display_name":"MAPK/ERK pathway","level":3,"score":0.555223286151886},{"id":"https://openalex.org/C80444323","wikidata":"https://www.wikidata.org/wiki/Q2878974","display_name":"Theoretical computer science","level":1,"score":0.48370081186294556},{"id":"https://openalex.org/C98045186","wikidata":"https://www.wikidata.org/wiki/Q205663","display_name":"Process (computing)","level":2,"score":0.48047035932540894},{"id":"https://openalex.org/C194995250","wikidata":"https://www.wikidata.org/wiki/Q531136","display_name":"Affordance","level":2,"score":0.47753727436065674},{"id":"https://openalex.org/C184337299","wikidata":"https://www.wikidata.org/wiki/Q1437428","display_name":"Semantics (computer science)","level":2,"score":0.4692378342151642},{"id":"https://openalex.org/C135315306","wikidata":"https://www.wikidata.org/wiki/Q866364","display_name":"Bisimulation","level":2,"score":0.45222264528274536},{"id":"https://openalex.org/C3018449070","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signalling pathways","level":3,"score":0.44823262095451355},{"id":"https://openalex.org/C39743133","wikidata":"https://www.wikidata.org/wiki/Q3262595","display_name":"Signalling","level":2,"score":0.4227638840675354},{"id":"https://openalex.org/C120314980","wikidata":"https://www.wikidata.org/wiki/Q180634","display_name":"Distributed computing","level":1,"score":0.38216283917427063},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.36441856622695923},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.3254165053367615},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.25546011328697205},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.18241170048713684},{"id":"https://openalex.org/C107457646","wikidata":"https://www.wikidata.org/wiki/Q207434","display_name":"Human\u2013computer interaction","level":1,"score":0.11713835597038269},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11575430631637573},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.10872092843055725}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1007/11905455_1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/11905455_1","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.65.9250","is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.65.9250","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.dcs.ed.ac.uk/pepa/RKIPTCSB06.pdf","raw_type":"text"},{"id":"pmh:oai:pure.ed.ac.uk:openaire/80b9a2c0-88aa-4387-85d1-feff7846bd19","is_oa":true,"landing_page_url":"https://www.research.ed.ac.uk/en/publications/80b9a2c0-88aa-4387-85d1-feff7846bd19","pdf_url":null,"source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Calder, M, Gilmore, S & Hillston, J 2006, Modelling the Influence of RKIP on the ERK Signalling Pathway Using the Stochastic Process Algebra PEPA. in C Priami, A Ingolfsdottir, B Mishra & H Riis Nielson (eds), Transactions on Computational Systems Biology VII. Lecture Notes in Computer Science, vol. 4230, pp. 1-23. https://doi.org/10.1007/11905455_1","raw_type":"contributionToPeriodical"},{"id":"pmh:oai:pure.ed.ac.uk:publications/80b9a2c0-88aa-4387-85d1-feff7846bd19","is_oa":false,"landing_page_url":"http://hdl.handle.net/20.500.11820/80b9a2c0-88aa-4387-85d1-feff7846bd19","pdf_url":null,"source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":""}],"best_oa_location":{"id":"pmh:oai:pure.ed.ac.uk:openaire/80b9a2c0-88aa-4387-85d1-feff7846bd19","is_oa":true,"landing_page_url":"https://www.research.ed.ac.uk/en/publications/80b9a2c0-88aa-4387-85d1-feff7846bd19","pdf_url":null,"source":{"id":"https://openalex.org/S4306400321","display_name":"Edinburgh Research Explorer (University of Edinburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I98677209","host_organization_name":"University of Edinburgh","host_organization_lineage":["https://openalex.org/I98677209"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Calder, M, Gilmore, S & Hillston, J 2006, Modelling the Influence of RKIP on the ERK Signalling Pathway Using the Stochastic Process Algebra PEPA. in C Priami, A Ingolfsdottir, B Mishra & H Riis Nielson (eds), Transactions on Computational Systems Biology VII. Lecture Notes in Computer Science, vol. 4230, pp. 1-23. https://doi.org/10.1007/11905455_1","raw_type":"contributionToPeriodical"},"sustainable_development_goals":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W253803806","https://openalex.org/W1493186690","https://openalex.org/W1498125516","https://openalex.org/W1501020965","https://openalex.org/W1518886905","https://openalex.org/W1556566737","https://openalex.org/W1566900355","https://openalex.org/W1594089636","https://openalex.org/W2007006124","https://openalex.org/W2021089599","https://openalex.org/W2029222199","https://openalex.org/W2030334004","https://openalex.org/W2097920274","https://openalex.org/W2106190666","https://openalex.org/W2110796675","https://openalex.org/W2117486132","https://openalex.org/W2135012291","https://openalex.org/W2161621619","https://openalex.org/W2162943184","https://openalex.org/W2504360851","https://openalex.org/W2561675875","https://openalex.org/W2915794166","https://openalex.org/W4206542816","https://openalex.org/W4243252343","https://openalex.org/W4244123356","https://openalex.org/W4252040407"],"related_works":["https://openalex.org/W2583399457","https://openalex.org/W2145366203","https://openalex.org/W2034743224","https://openalex.org/W2167838019","https://openalex.org/W2807761056","https://openalex.org/W2148160518","https://openalex.org/W2788556514","https://openalex.org/W1536150964","https://openalex.org/W2149848093","https://openalex.org/W2000514139"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":8},{"year":2014,"cited_by_count":6},{"year":2013,"cited_by_count":11},{"year":2012,"cited_by_count":5}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}