{"id":"https://openalex.org/W1533957288","doi":"https://doi.org/10.1007/11564126_30","title":"Characterization of Novel HIV Drug Resistance Mutations Using Clustering, Multidimensional Scaling and SVM-Based Feature Ranking","display_name":"Characterization of Novel HIV Drug Resistance Mutations Using Clustering, Multidimensional Scaling and SVM-Based Feature Ranking","publication_year":2005,"publication_date":"2005-01-01","ids":{"openalex":"https://openalex.org/W1533957288","doi":"https://doi.org/10.1007/11564126_30","mag":"1533957288"},"language":"en","primary_location":{"id":"doi:10.1007/11564126_30","is_oa":false,"landing_page_url":"https://doi.org/10.1007/11564126_30","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2108/42096","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072463966","display_name":"Tobias Sing","orcid":"https://orcid.org/0000-0001-7870-7012"},"institutions":[{"id":"https://openalex.org/I4210109712","display_name":"Max Planck Institute for Informatics","ror":"https://ror.org/01w19ak89","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210109712"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Tobias Sing","raw_affiliation_strings":["Max Planck Institute for Informatics, Saarbr\u00fccken, Germany"],"affiliations":[{"raw_affiliation_string":"Max Planck Institute for Informatics, Saarbr\u00fccken, Germany","institution_ids":["https://openalex.org/I4210109712"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080590367","display_name":"Valentina Svicher","orcid":"https://orcid.org/0000-0002-2377-504X"},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Valentina Svicher","raw_affiliation_strings":["University of Rome \u201cTor Vergata\u201d, Italy","University of Rome \"Tor Vergata\", Italy"],"affiliations":[{"raw_affiliation_string":"University of Rome \u201cTor Vergata\u201d, Italy","institution_ids":["https://openalex.org/I116067653"]},{"raw_affiliation_string":"University of Rome \"Tor Vergata\", Italy","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035497488","display_name":"Niko Beerenwinkel","orcid":"https://orcid.org/0000-0002-0573-6119"},"institutions":[{"id":"https://openalex.org/I95457486","display_name":"University of California, Berkeley","ror":"https://ror.org/01an7q238","country_code":"US","type":"education","lineage":["https://openalex.org/I95457486"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Niko Beerenwinkel","raw_affiliation_strings":["University of California, Berkeley, CA, USA"],"affiliations":[{"raw_affiliation_string":"University of California, Berkeley, CA, USA","institution_ids":["https://openalex.org/I95457486"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069733218","display_name":"Francesca Ceccherini\u2010Silberstein","orcid":"https://orcid.org/0000-0002-6024-5101"},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesca Ceccherini-Silberstein","raw_affiliation_strings":["University of Rome \u201cTor Vergata\u201d, Italy","University of Rome \"Tor Vergata\", Italy"],"affiliations":[{"raw_affiliation_string":"University of Rome \u201cTor Vergata\u201d, Italy","institution_ids":["https://openalex.org/I116067653"]},{"raw_affiliation_string":"University of Rome \"Tor Vergata\", Italy","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000627402","display_name":"Martin D\u00e4umer","orcid":null},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Martin D\u00e4umer","raw_affiliation_strings":["University of Cologne, Germany"],"affiliations":[{"raw_affiliation_string":"University of Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074420045","display_name":"Rolf Kaiser","orcid":"https://orcid.org/0000-0002-2640-2548"},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Rolf Kaiser","raw_affiliation_strings":["University of Cologne, Germany"],"affiliations":[{"raw_affiliation_string":"University of Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113657566","display_name":"Hauke Walter","orcid":null},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Hauke Walter","raw_affiliation_strings":["University of Erlangen-N\u00fcrnberg, Germany"],"affiliations":[{"raw_affiliation_string":"University of Erlangen-N\u00fcrnberg, Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086466371","display_name":"Klaus Korn","orcid":"https://orcid.org/0000-0003-1891-2107"},"institutions":[{"id":"https://openalex.org/I181369854","display_name":"Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg","ror":"https://ror.org/00f7hpc57","country_code":"DE","type":"education","lineage":["https://openalex.org/I181369854"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Klaus Korn","raw_affiliation_strings":["University of Erlangen-N\u00fcrnberg, Germany"],"affiliations":[{"raw_affiliation_string":"University of Erlangen-N\u00fcrnberg, Germany","institution_ids":["https://openalex.org/I181369854"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074555350","display_name":"Daniel Hoffmann","orcid":"https://orcid.org/0000-0003-2973-7869"},"institutions":[{"id":"https://openalex.org/I2800451603","display_name":"Center of Advanced European Studies and Research","ror":"https://ror.org/05350h943","country_code":"DE","type":"facility","lineage":["https://openalex.org/I2800451603"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Daniel Hoffmann","raw_affiliation_strings":["Center for Advanced European Studies and Research, Bonn, Germany"],"affiliations":[{"raw_affiliation_string":"Center for Advanced European Studies and Research, Bonn, Germany","institution_ids":["https://openalex.org/I2800451603"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025348858","display_name":"Mark Oette","orcid":null},"institutions":[{"id":"https://openalex.org/I44260953","display_name":"Heinrich Heine University D\u00fcsseldorf","ror":"https://ror.org/024z2rq82","country_code":"DE","type":"education","lineage":["https://openalex.org/I44260953"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Mark Oette","raw_affiliation_strings":["University of D\u00fcsseldorf, Germany"],"affiliations":[{"raw_affiliation_string":"University of D\u00fcsseldorf, Germany","institution_ids":["https://openalex.org/I44260953"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054617732","display_name":"J\u00fcrgen K. Rockstroh","orcid":"https://orcid.org/0000-0003-2858-3888"},"institutions":[{"id":"https://openalex.org/I135140700","display_name":"University of Bonn","ror":"https://ror.org/041nas322","country_code":"DE","type":"education","lineage":["https://openalex.org/I135140700"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"J\u00fcrgen K. Rockstroh","raw_affiliation_strings":["University of Bonn, Germany"],"affiliations":[{"raw_affiliation_string":"University of Bonn, Germany","institution_ids":["https://openalex.org/I135140700"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016657591","display_name":"Gert F\u00e4tkenheuer","orcid":null},"institutions":[{"id":"https://openalex.org/I180923762","display_name":"University of Cologne","ror":"https://ror.org/00rcxh774","country_code":"DE","type":"education","lineage":["https://openalex.org/I180923762"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Gert F\u00e4tkenheuer","raw_affiliation_strings":["University of Cologne, Germany"],"affiliations":[{"raw_affiliation_string":"University of Cologne, Germany","institution_ids":["https://openalex.org/I180923762"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091721224","display_name":"Carlo Federico Perno","orcid":"https://orcid.org/0000-0002-0825-5388"},"institutions":[{"id":"https://openalex.org/I116067653","display_name":"University of Rome Tor Vergata","ror":"https://ror.org/02p77k626","country_code":"IT","type":"education","lineage":["https://openalex.org/I116067653"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Carlo-Federico Perno","raw_affiliation_strings":["University of Rome \u201cTor Vergata\u201d, Italy","University of Rome \"Tor Vergata\", Italy"],"affiliations":[{"raw_affiliation_string":"University of Rome \u201cTor Vergata\u201d, Italy","institution_ids":["https://openalex.org/I116067653"]},{"raw_affiliation_string":"University of Rome \"Tor Vergata\", Italy","institution_ids":["https://openalex.org/I116067653"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5023556977","display_name":"Thomas Lengauer","orcid":"https://orcid.org/0000-0003-3801-2640"},"institutions":[{"id":"https://openalex.org/I4210109712","display_name":"Max Planck Institute for Informatics","ror":"https://ror.org/01w19ak89","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210109712"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Thomas Lengauer","raw_affiliation_strings":["Max Planck Institute for Informatics, Saarbr\u00fccken, Germany"],"affiliations":[{"raw_affiliation_string":"Max Planck Institute for Informatics, Saarbr\u00fccken, Germany","institution_ids":["https://openalex.org/I4210109712"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5072463966"],"corresponding_institution_ids":["https://openalex.org/I4210109712"],"apc_list":{"value":5000,"currency":"EUR","value_usd":5392},"apc_paid":null,"fwci":16.589,"has_fulltext":false,"cited_by_count":37,"citation_normalized_percentile":{"value":0.99276411,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"285","last_page":"296"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment","score":0.9991999864578247,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9973000288009644,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.9865999817848206,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cluster-analysis","display_name":"Cluster analysis","score":0.6056863069534302},{"id":"https://openalex.org/keywords/ranking","display_name":"Ranking (information retrieval)","score":0.6030336022377014},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5493147969245911},{"id":"https://openalex.org/keywords/computational-biology","display_name":"Computational biology","score":0.547056257724762},{"id":"https://openalex.org/keywords/mutation","display_name":"Mutation","score":0.49447107315063477},{"id":"https://openalex.org/keywords/feature","display_name":"Feature (linguistics)","score":0.4866245687007904},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.4316328465938568},{"id":"https://openalex.org/keywords/support-vector-machine","display_name":"Support vector machine","score":0.41628187894821167},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.4001554250717163},{"id":"https://openalex.org/keywords/genetics","display_name":"Genetics","score":0.3399896025657654},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.3220568895339966},{"id":"https://openalex.org/keywords/biology","display_name":"Biology","score":0.3006182312965393},{"id":"https://openalex.org/keywords/gene","display_name":"Gene","score":0.14304113388061523}],"concepts":[{"id":"https://openalex.org/C73555534","wikidata":"https://www.wikidata.org/wiki/Q622825","display_name":"Cluster analysis","level":2,"score":0.6056863069534302},{"id":"https://openalex.org/C189430467","wikidata":"https://www.wikidata.org/wiki/Q7293293","display_name":"Ranking (information retrieval)","level":2,"score":0.6030336022377014},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5493147969245911},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.547056257724762},{"id":"https://openalex.org/C501734568","wikidata":"https://www.wikidata.org/wiki/Q42918","display_name":"Mutation","level":3,"score":0.49447107315063477},{"id":"https://openalex.org/C2776401178","wikidata":"https://www.wikidata.org/wiki/Q12050496","display_name":"Feature (linguistics)","level":2,"score":0.4866245687007904},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.4316328465938568},{"id":"https://openalex.org/C12267149","wikidata":"https://www.wikidata.org/wiki/Q282453","display_name":"Support vector machine","level":2,"score":0.41628187894821167},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.4001554250717163},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3399896025657654},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.3220568895339966},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3006182312965393},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.14304113388061523},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1007/11564126_30","is_oa":false,"landing_page_url":"https://doi.org/10.1007/11564126_30","pdf_url":null,"source":{"id":"https://openalex.org/S106296714","display_name":"Lecture notes in computer science","issn_l":"0302-9743","issn":["0302-9743","1611-3349"],"is_oa":false,"is_in_doaj":false,"is_core":true,"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Lecture Notes in Computer Science","raw_type":"book-chapter"},{"id":"pmh:oai:art.torvergata.it:2108/42096","is_oa":true,"landing_page_url":"http://hdl.handle.net/2108/42096","pdf_url":null,"source":{"id":"https://openalex.org/S4306400993","display_name":"Cineca Institutional Research Information System (Tor Vergata University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I116067653","host_organization_name":"University of Rome Tor Vergata","host_organization_lineage":["https://openalex.org/I116067653"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"},{"id":"pmh:oai:escidoc.org:escidoc:2044579","is_oa":false,"landing_page_url":"http://hdl.handle.net/11858/00-001M-0000-001A-030B-3","pdf_url":null,"source":{"id":"https://openalex.org/S7407052962","display_name":"Max Planck Digital Library","issn_l":null,"issn":[],"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/conferenceObject"},{"id":"pmh:oai:zenodo.org:168454","is_oa":true,"landing_page_url":"https://www.openaccessrepository.it/record/168454","pdf_url":null,"source":{"id":"https://openalex.org/S4306402478","display_name":"INFM-OAR (INFN Catania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I4210116497","host_organization_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Catania","host_organization_lineage":["https://openalex.org/I4210116497"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/bookPart"}],"best_oa_location":{"id":"pmh:oai:art.torvergata.it:2108/42096","is_oa":true,"landing_page_url":"http://hdl.handle.net/2108/42096","pdf_url":null,"source":{"id":"https://openalex.org/S4306400993","display_name":"Cineca Institutional Research Information System (Tor Vergata University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":"https://openalex.org/I116067653","host_organization_name":"University of Rome Tor Vergata","host_organization_lineage":["https://openalex.org/I116067653"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/conferenceObject"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.8500000238418579,"id":"https://metadata.un.org/sdg/3"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W16447527","https://openalex.org/W1492020089","https://openalex.org/W1988215875","https://openalex.org/W2012290228","https://openalex.org/W2054688372","https://openalex.org/W2067419109","https://openalex.org/W2110065044","https://openalex.org/W2122799540","https://openalex.org/W2130563372","https://openalex.org/W2134312057","https://openalex.org/W2143426320","https://openalex.org/W2164032557","https://openalex.org/W2169192079","https://openalex.org/W2271871949","https://openalex.org/W4236479494","https://openalex.org/W6737880917"],"related_works":["https://openalex.org/W2090763504","https://openalex.org/W148178222","https://openalex.org/W2188500270","https://openalex.org/W2303858293","https://openalex.org/W2104657898","https://openalex.org/W1948992892","https://openalex.org/W1886884218","https://openalex.org/W2915512527","https://openalex.org/W2804364458","https://openalex.org/W1910826599"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-04-04T16:13:02.066488","created_date":"2025-10-10T00:00:00"}