{"id":"https://openalex.org/W4211035346","doi":"https://doi.org/10.1002/aisy.202100204","title":"Establishment of a Knowledge\u2010and\u2010Data\u2010Driven Artificial Intelligence System with Robustness and Interpretability in Laboratory Medicine","display_name":"Establishment of a Knowledge\u2010and\u2010Data\u2010Driven Artificial Intelligence System with Robustness and Interpretability in Laboratory Medicine","publication_year":2022,"publication_date":"2022-02-09","ids":{"openalex":"https://openalex.org/W4211035346","doi":"https://doi.org/10.1002/aisy.202100204"},"language":"en","primary_location":{"id":"doi:10.1002/aisy.202100204","is_oa":true,"landing_page_url":"https://doi.org/10.1002/aisy.202100204","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/aisy.202100204","source":{"id":"https://openalex.org/S4210212817","display_name":"Advanced Intelligent Systems","issn_l":"2640-4567","issn":["2640-4567"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Intelligent Systems","raw_type":"journal-article"},"type":"article","indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/aisy.202100204","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000728648","display_name":"Beilei Wang","orcid":"https://orcid.org/0000-0001-5404-260X"},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Beilei Wang","raw_affiliation_strings":["Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","Department of Marine Biomedicine and Polar Medicine Naval Special Medical Center  880 Xiangyin Road Shanghai 200433 China","Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China","Department of Marine Biomedicine and Polar Medicine Naval Special Medical Center 880 Xiangyin Road Shanghai 200433 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]},{"raw_affiliation_string":"Department of Marine Biomedicine and Polar Medicine Naval Special Medical Center  880 Xiangyin Road Shanghai 200433 China","institution_ids":["https://openalex.org/I177933477"]},{"raw_affiliation_string":"Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]},{"raw_affiliation_string":"Department of Marine Biomedicine and Polar Medicine Naval Special Medical Center 880 Xiangyin Road Shanghai 200433 China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113888475","display_name":"Jing Jie","orcid":null},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jie Jing","raw_affiliation_strings":["Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]},{"raw_affiliation_string":"Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023773680","display_name":"Xiaochun Huang","orcid":"https://orcid.org/0000-0002-6792-1555"},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaochun Huang","raw_affiliation_strings":["Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]},{"raw_affiliation_string":"Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Cheng Hua","orcid":null},"institutions":[{"id":"https://openalex.org/I183067930","display_name":"Shanghai Jiao Tong University","ror":"https://ror.org/0220qvk04","country_code":"CN","type":"education","lineage":["https://openalex.org/I183067930"]},{"id":"https://openalex.org/I4210159575","display_name":"Huashan Hospital","ror":"https://ror.org/05201qm87","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210159575"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Cheng Hua","raw_affiliation_strings":["Antai College of Economics and Management Shanghai Jiao Tong University  1954 Huashan Road Shanghai 200031 China","Antai College of Economics and Management Shanghai Jiao Tong University 1954 Huashan Road Shanghai 200031 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Antai College of Economics and Management Shanghai Jiao Tong University  1954 Huashan Road Shanghai 200031 China","institution_ids":["https://openalex.org/I183067930","https://openalex.org/I4210159575"]},{"raw_affiliation_string":"Antai College of Economics and Management Shanghai Jiao Tong University 1954 Huashan Road Shanghai 200031 China","institution_ids":["https://openalex.org/I183067930"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100680083","display_name":"Qin Qin","orcid":"https://orcid.org/0000-0002-6432-2944"},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qin Qin","raw_affiliation_strings":["Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]},{"raw_affiliation_string":"Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112337544","display_name":"Yin Jia","orcid":"https://orcid.org/0009-0003-1115-7038"},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yin Jia","raw_affiliation_strings":["Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]},{"raw_affiliation_string":"Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100443935","display_name":"Zhiyong Wang","orcid":"https://orcid.org/0000-0002-8043-0312"},"institutions":[{"id":"https://openalex.org/I116953780","display_name":"Tongji University","ror":"https://ror.org/03rc6as71","country_code":"CN","type":"education","lineage":["https://openalex.org/I116953780"]},{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiyong Wang","raw_affiliation_strings":["Department of Information Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","Department of Information Shanghai Fourth People's Hospital Tongji University School of Medicine  1279 Sanmen Road Shanghai 200081 China","Department of Information Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China","Department of Information Shanghai Fourth People's Hospital Tongji University School of Medicine 1279 Sanmen Road Shanghai 200081 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Information Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]},{"raw_affiliation_string":"Department of Information Shanghai Fourth People's Hospital Tongji University School of Medicine  1279 Sanmen Road Shanghai 200081 China","institution_ids":["https://openalex.org/I116953780"]},{"raw_affiliation_string":"Department of Information Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]},{"raw_affiliation_string":"Department of Information Shanghai Fourth People's Hospital Tongji University School of Medicine 1279 Sanmen Road Shanghai 200081 China","institution_ids":["https://openalex.org/I116953780"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041259291","display_name":"Lei Jiang","orcid":"https://orcid.org/0000-0002-8177-4037"},"institutions":[{"id":"https://openalex.org/I4210099558","display_name":"Shanghai Changzheng Hospital","ror":"https://ror.org/0103dxn66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210099558"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lei Jiang","raw_affiliation_strings":["Department of Rheumatology and Immunology Shanghai Changzheng Hospital Navy Military Medical University  415 Fengyang Road Shanghai 200003 China","Department of Rheumatology and Immunology Shanghai Changzheng Hospital Navy Military Medical University 415 Fengyang Road Shanghai 200003 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Rheumatology and Immunology Shanghai Changzheng Hospital Navy Military Medical University  415 Fengyang Road Shanghai 200003 China","institution_ids":["https://openalex.org/I4210099558"]},{"raw_affiliation_string":"Department of Rheumatology and Immunology Shanghai Changzheng Hospital Navy Military Medical University 415 Fengyang Road Shanghai 200003 China","institution_ids":["https://openalex.org/I4210099558"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009827386","display_name":"Bai Gao","orcid":null},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bai Gao","raw_affiliation_strings":["Department of Information Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","Department of Information Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Information Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]},{"raw_affiliation_string":"Department of Information Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069698190","display_name":"Lele Wu","orcid":"https://orcid.org/0000-0002-3806-5163"},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Lele Wu","raw_affiliation_strings":["Department of Information Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","Department of Information Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Information Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]},{"raw_affiliation_string":"Department of Information Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087927939","display_name":"Xianfei Zeng","orcid":null},"institutions":[{"id":"https://openalex.org/I180632629","display_name":"Xi'an International Studies University","ror":"https://ror.org/05gcme754","country_code":"CN","type":"education","lineage":["https://openalex.org/I180632629"]},{"id":"https://openalex.org/I37802460","display_name":"Northwest University","ror":"https://ror.org/00z3td547","country_code":"CN","type":"education","lineage":["https://openalex.org/I37802460"]},{"id":"https://openalex.org/I4210107780","display_name":"Xi'an Medical University","ror":"https://ror.org/01fmc2233","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210107780"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xianfei Zeng","raw_affiliation_strings":["School of Medicine Xi'an Area Medical Laboratory Center Northwest University  15 Gaoxin Road Xi'an 710000 China","School of Medicine Xi'an Area Medical Laboratory Center Northwest University 15 Gaoxin Road Xi'an 710000 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Medicine Xi'an Area Medical Laboratory Center Northwest University  15 Gaoxin Road Xi'an 710000 China","institution_ids":["https://openalex.org/I37802460","https://openalex.org/I4210107780","https://openalex.org/I180632629"]},{"raw_affiliation_string":"School of Medicine Xi'an Area Medical Laboratory Center Northwest University 15 Gaoxin Road Xi'an 710000 China","institution_ids":["https://openalex.org/I37802460"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039085769","display_name":"Fubo Wang","orcid":"https://orcid.org/0000-0002-2209-9932"},"institutions":[{"id":"https://openalex.org/I160354086","display_name":"Guangxi Medical University","ror":"https://ror.org/03dveyr97","country_code":"CN","type":"education","lineage":["https://openalex.org/I160354086"]},{"id":"https://openalex.org/I4210151238","display_name":"Center for Genomic Science","ror":"https://ror.org/04xbkmk86","country_code":"IT","type":"facility","lineage":["https://openalex.org/I30771326","https://openalex.org/I4210151238"]}],"countries":["CN","IT"],"is_corresponding":true,"raw_author_name":"Fubo Wang","raw_affiliation_strings":["Center for Genomic and Personalized Medicine Guangxi Medical University  22 Shuangyong Road Nanning 530021 China","Center for Genomic and Personalized Medicine Guangxi Medical University 22 Shuangyong Road Nanning 530021 China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Genomic and Personalized Medicine Guangxi Medical University  22 Shuangyong Road Nanning 530021 China","institution_ids":["https://openalex.org/I4210151238"]},{"raw_affiliation_string":"Center for Genomic and Personalized Medicine Guangxi Medical University 22 Shuangyong Road Nanning 530021 China","institution_ids":["https://openalex.org/I160354086"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008423769","display_name":"Chuanbin Mao","orcid":"https://orcid.org/0000-0002-8142-3659"},"institutions":[{"id":"https://openalex.org/I8692664","display_name":"University of Oklahoma","ror":"https://ror.org/02aqsxs83","country_code":"US","type":"education","lineage":["https://openalex.org/I8692664"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Chuanbin Mao","raw_affiliation_strings":["Department of Chemistry and Biochemistry Stephenson Life Sciences Research Center University of Oklahoma  101 Stephenson Parkway Norman Oklahoma 73019-5300 USA","Department of Chemistry and Biochemistry Stephenson Life Sciences Research Center University of Oklahoma 101 Stephenson Parkway Norman Oklahoma 73019-5300 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry and Biochemistry Stephenson Life Sciences Research Center University of Oklahoma  101 Stephenson Parkway Norman Oklahoma 73019-5300 USA","institution_ids":["https://openalex.org/I8692664"]},{"raw_affiliation_string":"Department of Chemistry and Biochemistry Stephenson Life Sciences Research Center University of Oklahoma 101 Stephenson Parkway Norman Oklahoma 73019-5300 USA","institution_ids":["https://openalex.org/I8692664"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061964536","display_name":"Shanrong Liu","orcid":"https://orcid.org/0000-0002-4891-8713"},"institutions":[{"id":"https://openalex.org/I177933477","display_name":"Second Military Medical University","ror":"https://ror.org/04tavpn47","country_code":"CN","type":"education","lineage":["https://openalex.org/I177933477"]},{"id":"https://openalex.org/I4210115928","display_name":"Changhai Hospital","ror":"https://ror.org/02bjs0p66","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115928"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Shanrong Liu","raw_affiliation_strings":["Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China"],"raw_orcid":"https://orcid.org/0000-0002-4891-8713","affiliations":[{"raw_affiliation_string":"Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University  168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]},{"raw_affiliation_string":"Department of Laboratory Diagnostics Changhai Hospital Navy Military Medical University 168 Changhai Road Shanghai 200433 China","institution_ids":["https://openalex.org/I4210115928","https://openalex.org/I177933477"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":14,"corresponding_author_ids":["https://openalex.org/A5008423769","https://openalex.org/A5039085769","https://openalex.org/A5061964536"],"corresponding_institution_ids":["https://openalex.org/I160354086","https://openalex.org/I177933477","https://openalex.org/I4210115928","https://openalex.org/I4210151238","https://openalex.org/I8692664"],"apc_list":{"value":2750,"currency":"USD","value_usd":2750},"apc_paid":{"value":2750,"currency":"USD","value_usd":2750},"fwci":0.487,"has_fulltext":true,"cited_by_count":9,"citation_normalized_percentile":{"value":0.70374886,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"4","issue":"5","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.9902999997138977,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11636","display_name":"Artificial Intelligence in Healthcare and Education","score":0.9902999997138977,"subfield":{"id":"https://openalex.org/subfields/2718","display_name":"Health Informatics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12026","display_name":"Explainable Artificial Intelligence (XAI)","score":0.9901999831199646,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T13702","display_name":"Machine Learning in Healthcare","score":0.9854000210762024,"subfield":{"id":"https://openalex.org/subfields/1702","display_name":"Artificial Intelligence"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/interpretability","display_name":"Interpretability","score":0.9530378580093384},{"id":"https://openalex.org/keywords/artificial-intelligence","display_name":"Artificial intelligence","score":0.7262564897537231},{"id":"https://openalex.org/keywords/machine-learning","display_name":"Machine learning","score":0.5950098037719727},{"id":"https://openalex.org/keywords/computer-science","display_name":"Computer science","score":0.5636571049690247},{"id":"https://openalex.org/keywords/big-data","display_name":"Big data","score":0.5191423296928406},{"id":"https://openalex.org/keywords/robustness","display_name":"Robustness (evolution)","score":0.5018000602722168},{"id":"https://openalex.org/keywords/medical-diagnosis","display_name":"Medical diagnosis","score":0.43686628341674805},{"id":"https://openalex.org/keywords/applications-of-artificial-intelligence","display_name":"Applications of artificial intelligence","score":0.4200275242328644},{"id":"https://openalex.org/keywords/medical-laboratory","display_name":"Medical laboratory","score":0.41634446382522583},{"id":"https://openalex.org/keywords/data-science","display_name":"Data science","score":0.3531706631183624},{"id":"https://openalex.org/keywords/medicine","display_name":"Medicine","score":0.24998846650123596},{"id":"https://openalex.org/keywords/data-mining","display_name":"Data mining","score":0.2165313959121704},{"id":"https://openalex.org/keywords/pathology","display_name":"Pathology","score":0.16553816199302673}],"concepts":[{"id":"https://openalex.org/C2781067378","wikidata":"https://www.wikidata.org/wiki/Q17027399","display_name":"Interpretability","level":2,"score":0.9530378580093384},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.7262564897537231},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.5950098037719727},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5636571049690247},{"id":"https://openalex.org/C75684735","wikidata":"https://www.wikidata.org/wiki/Q858810","display_name":"Big data","level":2,"score":0.5191423296928406},{"id":"https://openalex.org/C63479239","wikidata":"https://www.wikidata.org/wiki/Q7353546","display_name":"Robustness (evolution)","level":3,"score":0.5018000602722168},{"id":"https://openalex.org/C534262118","wikidata":"https://www.wikidata.org/wiki/Q177719","display_name":"Medical diagnosis","level":2,"score":0.43686628341674805},{"id":"https://openalex.org/C157170001","wikidata":"https://www.wikidata.org/wiki/Q4781507","display_name":"Applications of artificial intelligence","level":2,"score":0.4200275242328644},{"id":"https://openalex.org/C44519122","wikidata":"https://www.wikidata.org/wiki/Q2296168","display_name":"Medical laboratory","level":2,"score":0.41634446382522583},{"id":"https://openalex.org/C2522767166","wikidata":"https://www.wikidata.org/wiki/Q2374463","display_name":"Data science","level":1,"score":0.3531706631183624},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24998846650123596},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.2165313959121704},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.16553816199302673},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1002/aisy.202100204","is_oa":true,"landing_page_url":"https://doi.org/10.1002/aisy.202100204","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/aisy.202100204","source":{"id":"https://openalex.org/S4210212817","display_name":"Advanced Intelligent Systems","issn_l":"2640-4567","issn":["2640-4567"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Intelligent Systems","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:9cba12ad35ac489b8fcaf44227d3ad7e","is_oa":false,"landing_page_url":"https://doaj.org/article/9cba12ad35ac489b8fcaf44227d3ad7e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Advanced Intelligent Systems, Vol 4, Iss 5, Pp n/a-n/a (2022)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1002/aisy.202100204","is_oa":true,"landing_page_url":"https://doi.org/10.1002/aisy.202100204","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/aisy.202100204","source":{"id":"https://openalex.org/S4210212817","display_name":"Advanced Intelligent Systems","issn_l":"2640-4567","issn":["2640-4567"],"is_oa":true,"is_in_doaj":true,"is_core":true,"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advanced Intelligent Systems","raw_type":"journal-article"},"sustainable_development_goals":[],"awards":[{"id":"https://openalex.org/G7888760843","display_name":null,"funder_award_id":"20511101200","funder_id":"https://openalex.org/F4320321885","funder_display_name":"Science and Technology Commission of Shanghai Municipality"}],"funders":[{"id":"https://openalex.org/F4320321885","display_name":"Science and Technology Commission of Shanghai Municipality","ror":"https://ror.org/03kt66j61"},{"id":"https://openalex.org/F4320322370","display_name":"East China Normal University","ror":"https://ror.org/02n96ep67"},{"id":"https://openalex.org/F4320325435","display_name":"Changhai Hospital of Shanghai","ror":"https://ror.org/02bjs0p66"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W4211035346.pdf","grobid_xml":"https://content.openalex.org/works/W4211035346.grobid-xml"},"referenced_works_count":26,"referenced_works":["https://openalex.org/W2007106708","https://openalex.org/W2101026637","https://openalex.org/W2132453167","https://openalex.org/W2163922914","https://openalex.org/W2300445845","https://openalex.org/W2557738935","https://openalex.org/W2581082771","https://openalex.org/W2587305359","https://openalex.org/W2598442119","https://openalex.org/W2741016737","https://openalex.org/W2762732341","https://openalex.org/W2788633781","https://openalex.org/W2795609817","https://openalex.org/W2899876413","https://openalex.org/W2903438096","https://openalex.org/W2905810301","https://openalex.org/W2906295032","https://openalex.org/W2927351257","https://openalex.org/W2934399013","https://openalex.org/W2946867497","https://openalex.org/W2997681568","https://openalex.org/W2998175747","https://openalex.org/W3008472299","https://openalex.org/W3080441768","https://openalex.org/W3092489655","https://openalex.org/W3178537070"],"related_works":["https://openalex.org/W4385957992","https://openalex.org/W4229079080","https://openalex.org/W4206534706","https://openalex.org/W4385965371","https://openalex.org/W4200027074","https://openalex.org/W4386025632","https://openalex.org/W3006943036","https://openalex.org/W3014300295","https://openalex.org/W4200511449","https://openalex.org/W4211177414"],"abstract_inverted_index":{"Laboratory":[0],"medicine":[1],"plays":[2],"an":[3,76,183],"important":[4],"role":[5],"in":[6,20,52,146,155,166,176],"clinical":[7,22,169,200],"diagnosis.":[8,95,201],"However,":[9],"no":[10],"laboratory\u2010based":[11,94],"artificial":[12],"intelligence":[13],"(AI)":[14],"diagnostic":[15,62],"system":[16,63,186],"has":[17],"been":[18,36],"applied":[19],"current":[21],"practice":[23],"due":[24],"to":[25,44,90],"the":[26,46,92,131,199],"lack":[27],"of":[28,192],"robustness":[29],"and":[30,82,85,107,127,140,164,172],"interpretability.":[31],"Although":[32],"many":[33],"attempts":[34],"have":[35],"made,":[37],"it":[38],"is":[39,64,182],"still":[40],"difficult":[41],"for":[42,125,133],"doctors":[43],"adopt":[45],"existing":[47],"machine":[48],"learning":[49],"(ML)":[50],"patterns":[51],"interpreting":[53,177],"laboratory":[54,61,105],"(lab)":[55],"big":[56,194],"data.":[57],"Here,":[58],"a":[59,189],"knowledge\u2010and\u2010data\u2010driven":[60],"developed,":[65],"termed":[66],"AI\u2010based":[67],"Lab":[68],"tEst":[69],"tO":[70],"diagNosis":[71],"(AI":[72],"LEON),":[73],"by":[74],"integrating":[75],"innovative":[77],"knowledge":[78],"graph":[79],"analysis":[80],"framework":[81],"\u201cmixed":[83],"XGboost":[84],"Genetic":[86],"Algorithm":[87],"(MiXG)\u201d":[88],"technique":[89],"simulate":[91],"doctor's":[93],"To":[96],"establish":[97],"AI":[98,136,159,180],"LEON,":[99],"we":[100],"included":[101],"89":[102],"116":[103],"949":[104],"data":[106,112],"10":[108],"423":[109],"581":[110],"diagnosis":[111],"points":[113],"from":[114],"730":[115],"113":[116],"participants.":[117],"Among":[118],"them,":[119],"686":[120],"626":[121],"participants":[122],"were":[123],"recruited":[124],"training":[126],"validating":[128],"purposes":[129],"with":[130],"remaining":[132],"testing":[134],"purposes.":[135],"LEON":[137,160,181],"automatically":[138],"identified":[139],"analyzed":[141],"2071":[142],"lab":[143,178,193],"indexes,":[144],"resulting":[145],"multiple":[147],"disease":[148],"recommendations":[149],"that":[150,187],"involved":[151],"441":[152],"common":[153],"diseases":[154],"ten":[156],"organ":[157],"systems.":[158],"exhibited":[161],"outstanding":[162],"transparency":[163],"interpretability":[165],"three":[167],"universal":[168],"application":[170],"scenarios":[171],"outperformed":[173],"human":[174],"physicians":[175],"reports.":[179],"advanced":[184],"intelligent":[185],"enables":[188],"comprehensive":[190],"interpretation":[191],"data,":[195],"which":[196],"substantially":[197],"improves":[198]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3}],"updated_date":"2026-05-21T06:26:12.895304","created_date":"2025-10-10T00:00:00"}