{"id":"https://openalex.org/W99749720","doi":null,"title":"Serum zinc and copper status in dyslipidaemic patients with and without established coronary artery disease.","display_name":"Serum zinc and copper status in dyslipidaemic patients with and without established coronary artery disease.","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W99749720","mag":"99749720","pmid":"https://pubmed.ncbi.nlm.nih.gov/19097489"},"language":"en","primary_location":{"id":"pmid:19097489","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19097489","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical laboratory","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100611777","display_name":"Majid Ghayour\u2010Mobarhan","orcid":"https://orcid.org/0000-0002-1081-6754","observed_orcids":["https://orcid.org/0000-0002-1081-6754","https://orcid.org/0000-0001-5947-8904","https://orcid.org/0000-0002-2482-2450","https://orcid.org/0000-0003-2852-7632","https://orcid.org/0000-0001-5384-7481","https://orcid.org/0000-0003-4088-0308","https://orcid.org/0000-0002-9319-9957"]},"institutions":[{"id":"https://openalex.org/I28290843","display_name":"University of Surrey","ror":"https://ror.org/00ks66431","country_code":"GB","type":"education","lineage":["https://openalex.org/I28290843"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"Majid Ghayour-Mobarhan","raw_affiliation_strings":["Centre for Clinical Science & Measurement, School of Biomedical & Molecular Science, University of Surrey, Guildford, Surrey, United Kingdom"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre for Clinical Science & Measurement, School of Biomedical & Molecular Science, University of Surrey, Guildford, Surrey, United Kingdom","institution_ids":["https://openalex.org/I28290843"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Andrew Taylor","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Andrew Taylor","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086009382","display_name":"Seyyed Mohammad Reza Kazemi\u2010Bajestani","orcid":"https://orcid.org/0000-0002-9509-7030","observed_orcids":["https://orcid.org/0000-0002-9509-7030"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Seyyed Mohammad Reza Kazemi-Bajestani","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051134598","display_name":"Susan A. Lanham-New","orcid":"https://orcid.org/0000-0003-3153-6345","observed_orcids":["https://orcid.org/0000-0003-3153-6345"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Susan Lanham-New","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101848300","display_name":"David J. Lamb","orcid":"https://orcid.org/0000-0003-3097-6189","observed_orcids":["https://orcid.org/0000-0003-3097-6189"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David J Lamb","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050065543","display_name":"Nandita Vaidya","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Nandita Vaidya","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013704320","display_name":"Callum Livingstone","orcid":"https://orcid.org/0000-0002-3098-8246","observed_orcids":["https://orcid.org/0000-0002-3098-8246"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Callum Livingstone","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Tim Wang","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tim Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5038854437","display_name":"Gordon A. Ferns","orcid":"https://orcid.org/0000-0002-0957-8349","observed_orcids":["https://orcid.org/0000-0002-0957-8349"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gordon A A Ferns","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.843,"has_fulltext":false,"cited_by_count":27,"citation_normalized_percentile":{"value":0.88306556,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"54","issue":"9-10","first_page":"321","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10915","display_name":"Trace Elements in Health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10915","display_name":"Trace Elements in Health","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12280","display_name":"Magnesium in Health and Disease","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/serum-zinc","display_name":"serum zinc","score":0.828000009059906},{"id":"https://openalex.org/keywords/serum-copper","display_name":"serum copper","score":0.9990000128746033},{"id":"https://openalex.org/keywords/dyslipidemia","display_name":"dyslipidemia","score":0.8930000066757202},{"id":"https://openalex.org/keywords/coronary-artery-disease","display_name":"coronary artery disease","score":1.0},{"id":"https://openalex.org/keywords/trace-element-status","display_name":"trace element status","score":0.7369999885559082},{"id":"https://openalex.org/keywords/copper-zinc-ratio","display_name":"copper/zinc ratio","score":0.9890000224113464},{"id":"https://openalex.org/keywords/c-reactive-protein","display_name":"C-reactive protein","score":0.9580000042915344},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.75},{"id":"https://openalex.org/keywords/food-consumption","display_name":"dietary intake","score":0.7110000252723694},{"id":"https://openalex.org/keywords/atherosclerosis","display_name":"atherosclerosis","score":0.7360000014305115},{"id":"https://openalex.org/keywords/dietary-fat","display_name":"dietary fat","score":0.48899999260902405},{"id":"https://openalex.org/keywords/dietary-protein","display_name":"dietary protein","score":0.8059999942779541},{"id":"https://openalex.org/keywords/micronutrients","display_name":"micronutrients","score":0.8700000047683716},{"id":"https://openalex.org/keywords/food-frequency-questionnaire","display_name":"food frequency questionnaire","score":0.4860000014305115},{"id":"https://openalex.org/keywords/coronary-risk-factors","display_name":"coronary risk factors","score":0.5509999990463257},{"id":"https://openalex.org/keywords/coronary-artery-bypass-grafting","display_name":"coronary artery bypass grafting","score":0.375},{"id":"https://openalex.org/keywords/myocardial-infarction","display_name":"myocardial infarction","score":0.5720000267028809}],"concepts":[{"id":"https://openalex.org/C535196362","wikidata":"https://www.wikidata.org/wiki/Q758","display_name":"Zinc","level":2,"score":0.7521798610687256},{"id":"https://openalex.org/C544778455","wikidata":"https://www.wikidata.org/wiki/Q753","display_name":"Copper","level":2,"score":0.7405664920806885},{"id":"https://openalex.org/C28452662","wikidata":"https://www.wikidata.org/wiki/Q422752","display_name":"Ceruloplasmin","level":2,"score":0.7251051068305969},{"id":"https://openalex.org/C2778213512","wikidata":"https://www.wikidata.org/wiki/Q844935","display_name":"Coronary artery disease","level":2,"score":0.7014451026916504},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6151866912841797},{"id":"https://openalex.org/C14522933","wikidata":"https://www.wikidata.org/wiki/Q531507","display_name":"Micronutrient","level":2,"score":0.5948707461357117},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5459042191505432},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4939268231391907},{"id":"https://openalex.org/C2781195455","wikidata":"https://www.wikidata.org/wiki/Q422766","display_name":"C-reactive protein","level":3,"score":0.42594730854034424},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.364762544631958},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.33080849051475525},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.24919524788856506},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1610604226589203},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.09078842401504517}],"mesh":[{"descriptor_ui":"D002097","descriptor_name":"C-Reactive Protein","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002570","descriptor_name":"Ceruloplasmin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003300","descriptor_name":"Copper","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015032","descriptor_name":"Zinc","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D050171","descriptor_name":"Dyslipidemias","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D050171","descriptor_name":"Dyslipidemias","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false}],"locations_count":5,"locations":[{"id":"pmid:19097489","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19097489","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical laboratory","raw_type":"Journal Article"},{"id":"pmh:oai:alma.44SUR_INST:11139911510002346","doi":null,"is_oa":false,"landing_page_url":"http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&amp;SrcApp=PARTNER_APP&amp;SrcAuth=LinksAMR&amp;KeyUT=000261502800001&amp;DestLinkType=FullRecord&amp;DestApp=ALL_WOS&amp;UsrCustomerID=11d2a86992e85fb529977dad66a846d5","pdf_url":null,"source":{"id":"https://openalex.org/S4210197018","display_name":"Open Research (University of Surrey)","issn_l":"2688-268X","issn":["2688-268X","2688-3988"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","poland-20","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"text"},{"id":"pmh:oai:epubs.surrey.ac.uk:821677","doi":null,"is_oa":false,"landing_page_url":"http://epubs.surrey.ac.uk/821677/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400680","display_name":"Surrey Research Insight Open Access (The University of Surrey)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I28290843","host_organization_name":"University of Surrey","host_organization_lineage":["https://openalex.org/I28290843"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Article"},{"id":"pmh:oai:figshare.com:article/23391824","doi":null,"is_oa":false,"landing_page_url":"https://figshare.com/articles/journal_contribution/Serum_zinc_and_copper_status_in_dyslipidaemic_patients_with_and_without_established_coronary_artery_disease/23391824","pdf_url":null,"source":{"id":"https://openalex.org/S4377196282","display_name":"Figshare","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210132348","host_organization_name":"Figshare (United Kingdom)","host_organization_lineage":["https://openalex.org/I4210132348"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Text"},{"id":"mag:99749720","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19097489","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2053765489","https://openalex.org/W3111823107","https://openalex.org/W3135404858","https://openalex.org/W2040244097","https://openalex.org/W4400306641","https://openalex.org/W1994698104","https://openalex.org/W1988442181","https://openalex.org/W1978009099","https://openalex.org/W4402750330","https://openalex.org/W2094303907"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Aspects":[1],"of":[2,39,45,66,100,134,276,307,325],"trace":[3],"element":[4],"status":[5,74],"have":[6],"previously":[7],"been":[8,25],"investigated":[9],"as":[10],"possible":[11],"contributory":[12],"factors":[13],"to":[14,157,228,256,303,317],"atherosclerosis.":[15],"In":[16],"this":[17],"present":[18],"study":[19],"a":[20,63,304,323],"more":[21],"comprehensive":[22],"approach":[23],"has":[24],"taken,":[26],"looking":[27],"at":[28,116],"the":[29,67,92,117,131,153,225,318],"relationship":[30,69],"between":[31,70],"dietary":[32,132,272],"macro-":[33],"and":[34,41,43,58,72,75,120,136,145,197,217,242,249,261,269,274,298],"micronutrient":[35],"intake,":[36],"serum":[37,237,244,295],"concentrations":[38],"zinc":[40,73,135,245,270],"copper,":[42,140],"markers":[44,275],"inflammation":[46,277],"in":[47,96,152,224,267,280,294,311],"dyslipidaemic":[48],"patients":[49,85,102,226,258,281],"with":[50,231,282,284,290],"or":[51,285,321],"without":[52,259,286],"established":[53,104,232,287],"coronary":[54,76],"artery":[55],"disease":[56,77],"(CAD)":[57],"healthy":[59,262],"controls,":[60],"so":[61],"that":[62],"clearer":[64],"understanding":[65],"potential":[68],"copper":[71,268,297],"may":[78,300,314],"be":[79,301,322],"ascertained.":[80],"METHODS":[81],"AND":[82],"MATERIALS:":[83],"Dyslipidaemic":[84],"(n":[86,108],"=":[87,109],"238)":[88],"were":[89,111,149,220,278],"recruited":[90,112],"from":[91,113],"local":[93,118],"General":[94],"Hospital":[95],"Guildford,":[97],"UK.":[98],"Fifty-five":[99],"these":[101],"had":[103,234],"CAD.":[105],"Control":[106],"subjects":[107],"135)":[110],"among":[114],"employees":[115],"University":[119],"Hospital.":[121],"A":[122],"validated":[123],"food":[124],"frequency":[125],"questionnaire":[126],"was":[127],"used":[128],"for":[129],"estimating":[130],"intake":[133,273],"copper.":[137],"RESULTS:":[138],"Serum":[139],"copper/caeruloplasmin":[141,172],"ratio,":[142,144],"zinc/copper":[143,185,218,250,312],"C-reactive":[146],"protein":[147],"(CRP)":[148],"significantly":[150,222,235],"different":[151],"patient":[154],"groups":[155],"compared":[156,227,255,289],"controls":[158],"[serum":[159],"copper:":[160],"17.20":[161],"+/-":[162,166,175,179,188,192],"0.2":[163],"v":[164,177,190,201],"15.91":[165],"0.29":[167],"micromol/L,":[168],"p":[169,182,194,205],"<":[170,183,195,206,240,247,253],"0.001;":[171],"ratio:":[173,186],"111.37":[174],"2.18":[176],"100.63":[178],"2.93":[180],"micromol/g,":[181],"0.01;":[184],"0.85":[187],"0.01":[189],"0.90":[191],"0.01,":[193],"0.05;":[196],"CRP:":[198],"1.25":[199],"(0.42-3.26)":[200],"0.58":[202],"(0.17-1.42)":[203],"mg/L,":[204],"0.001].":[207],"Dietary":[208],"protein,":[209],"total":[210],"fat,":[211,215],"starch,":[212],"fibre,":[213],"monounsaturated":[214],"zinc,":[216],"ratio":[219,251],"also":[221],"higher":[223,236],"controls.":[229,263],"Patients":[230],"CAD":[233,260,319],"CRP":[238],"(p":[239,246,252],"0.05)":[241],"lower":[243],"0.01)":[248,254],"both":[257],"CONCLUSION:":[264],"Significant":[265],"differences":[266],"status,":[271],"observed":[279],"dyslipidaemia,":[283],"CAD,":[288],"control":[291],"subjects.":[292],"Differences":[293],"CRP,":[296],"caeruloplasmin":[299],"related":[302],"heightened":[305],"state":[306],"inflammation.":[308],"The":[309],"imbalance":[310],"metabolism":[313],"either":[315],"contribute":[316],"risk":[320],"consequence":[324],"an":[326],"acute":[327],"phase":[328],"response.":[329]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":6}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}