{"id":"https://openalex.org/W99362537","doi":null,"title":"Probiotics and medical nutrition therapy.","display_name":"Probiotics and medical nutrition therapy.","publication_year":2004,"publication_date":"2004-04-01","ids":{"openalex":"https://openalex.org/W99362537","mag":"99362537","pmid":"https://pubmed.ncbi.nlm.nih.gov/15481739","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1482314"},"language":"en","primary_location":{"id":"pmid:15481739","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15481739","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrition in clinical care : an official publication of Tufts University","raw_type":"Journal Article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1482314","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108600815","display_name":"Amy Christine Brown","orcid":"https://orcid.org/0000-0001-6994-1472","observed_orcids":["https://orcid.org/0000-0001-6994-1472"]},"institutions":[{"id":"https://openalex.org/I117965899","display_name":"University of Hawai\u02bbi at M\u0101noa","ror":"https://ror.org/01wspgy28","country_code":"US","type":"education","lineage":["https://openalex.org/I117965899"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Amy C Brown","raw_affiliation_strings":["Department of Human Nutrition, Food & Animal Sciences, University of Hawaii at Manoa, 1955 East West Road, Room 216, Honolulu, HI 96822, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Human Nutrition, Food & Animal Sciences, University of Hawaii at Manoa, 1955 East West Road, Room 216, Honolulu, HI 96822, USA","institution_ids":["https://openalex.org/I117965899"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5000151604","display_name":"Ana Valiere","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ana Valiere","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.5187,"has_fulltext":false,"cited_by_count":204,"citation_normalized_percentile":{"value":0.42207792,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"7","issue":"2","first_page":"56","last_page":"68"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11294","display_name":"Infant Nutrition and Health","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/probiotics","display_name":"probiotics","score":1.0},{"id":"https://openalex.org/keywords/medical-nutrition-therapy","display_name":"medical nutrition therapy","score":0.9950000047683716},{"id":"https://openalex.org/keywords/live-microorganisms","display_name":"live microorganisms","score":0.8899999856948853},{"id":"https://openalex.org/keywords/health-benefits","display_name":"health benefits","score":0.7110000252723694},{"id":"https://openalex.org/keywords/fermented-dairy-products","display_name":"fermented dairy products","score":0.7699999809265137},{"id":"https://openalex.org/keywords/diarrhea","display_name":"diarrhea","score":0.9649999737739563},{"id":"https://openalex.org/keywords/gastroenteritis","display_name":"gastroenteritis","score":0.9850000143051147},{"id":"https://openalex.org/keywords/irritable-bowel-syndrome","display_name":"irritable bowel syndrome","score":1.0},{"id":"https://openalex.org/keywords/inflammatory-bowel-disease","display_name":"inflammatory bowel disease","score":0.9869999885559082},{"id":"https://openalex.org/keywords/crohn-s-disease","display_name":"Crohn's disease","score":0.8450000286102295},{"id":"https://openalex.org/keywords/ulcerative-colitis","display_name":"ulcerative colitis","score":1.0},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.718999981880188},{"id":"https://openalex.org/keywords/immune-function","display_name":"immune function","score":0.9520000219345093},{"id":"https://openalex.org/keywords/lactase-deficiency","display_name":"lactase deficiency","score":0.8889999985694885},{"id":"https://openalex.org/keywords/infant-allergy","display_name":"infant allergy","score":0.9290000200271606},{"id":"https://openalex.org/keywords/failure-to-thrive","display_name":"failure to thrive","score":0.9629999995231628},{"id":"https://openalex.org/keywords/hyperlipidemia","display_name":"hyperlipidemia","score":0.9950000047683716},{"id":"https://openalex.org/keywords/liver-disease","display_name":"liver disease","score":0.7910000085830688},{"id":"https://openalex.org/keywords/helicobacter-pylori-infection","display_name":"Helicobacter pylori infection","score":0.9129999876022339},{"id":"https://openalex.org/keywords/genitourinary-tract-infection","display_name":"genitourinary infections","score":0.9909999966621399}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.939319372177124},{"id":"https://openalex.org/C2780255968","wikidata":"https://www.wikidata.org/wiki/Q1816730","display_name":"Probiotic","level":3,"score":0.5745959281921387},{"id":"https://openalex.org/C2779802037","wikidata":"https://www.wikidata.org/wiki/Q40878","display_name":"Diarrhea","level":2,"score":0.5432073473930359},{"id":"https://openalex.org/C75141282","wikidata":"https://www.wikidata.org/wiki/Q2358629","display_name":"Medical nutrition therapy","level":2,"score":0.5410242676734924},{"id":"https://openalex.org/C2776917539","wikidata":"https://www.wikidata.org/wiki/Q1497481","display_name":"Failure to thrive","level":2,"score":0.5366228818893433},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5297725200653076},{"id":"https://openalex.org/C2778271842","wikidata":"https://www.wikidata.org/wiki/Q838966","display_name":"Irritable bowel syndrome","level":2,"score":0.522339940071106},{"id":"https://openalex.org/C2780479503","wikidata":"https://www.wikidata.org/wiki/Q1477","display_name":"Ulcerative colitis","level":3,"score":0.5052745938301086},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.4622710645198822},{"id":"https://openalex.org/C2778260677","wikidata":"https://www.wikidata.org/wiki/Q917447","display_name":"Inflammatory bowel disease","level":3,"score":0.44942402839660645},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.41512367129325867},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.37281423807144165},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004066","descriptor_name":"Digestive System Diseases","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D005183","descriptor_name":"Failure to Thrive","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006949","descriptor_name":"Hyperlipidemias","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D007154","descriptor_name":"Immune System Diseases","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016481","descriptor_name":"Helicobacter Infections","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D019936","descriptor_name":"Probiotics","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D044623","descriptor_name":"Nutrition Therapy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D052776","descriptor_name":"Female Urogenital Diseases","qualifier_ui":"Q000178","qualifier_name":"diet therapy","is_major_topic":false},{"descriptor_ui":"D052801","descriptor_name":"Male Urogenital Diseases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:15481739","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15481739","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrition in clinical care : an official publication of Tufts University","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:1482314","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1482314","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nutr Clin Care","raw_type":"Text"},{"id":"mag:99362537","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15481739","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:1482314","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1482314","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nutr Clin Care","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G147334744","display_name":"RCMI CLINICAL RESEARCH INFRASTRUCTURE INITIATIVE (RCRII)","funder_award_id":"5p20rr011091-15","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":113,"referenced_works":["https://openalex.org/W68552834","https://openalex.org/W76196308","https://openalex.org/W95527901","https://openalex.org/W127956282","https://openalex.org/W183383422","https://openalex.org/W194124128","https://openalex.org/W1277933029","https://openalex.org/W1556080378","https://openalex.org/W1626154196","https://openalex.org/W1698486782","https://openalex.org/W1727711006","https://openalex.org/W1824816933","https://openalex.org/W1891619118","https://openalex.org/W1904807433","https://openalex.org/W1912199429","https://openalex.org/W1922511005","https://openalex.org/W1926849493","https://openalex.org/W1927236436","https://openalex.org/W1940221461","https://openalex.org/W1944775178","https://openalex.org/W1946934775","https://openalex.org/W1947478688","https://openalex.org/W1966179285","https://openalex.org/W1968465136","https://openalex.org/W1975391560","https://openalex.org/W1976879190","https://openalex.org/W1977907198","https://openalex.org/W1982851558","https://openalex.org/W1983790785","https://openalex.org/W1985742296","https://openalex.org/W1986823910","https://openalex.org/W1987296038","https://openalex.org/W1988439456","https://openalex.org/W1989761204","https://openalex.org/W1991732418","https://openalex.org/W1994962816","https://openalex.org/W1995614850","https://openalex.org/W1997448297","https://openalex.org/W2002121713","https://openalex.org/W2010235735","https://openalex.org/W2016264735","https://openalex.org/W2017569060","https://openalex.org/W2018565978","https://openalex.org/W2023806986","https://openalex.org/W2023916111","https://openalex.org/W2024677931","https://openalex.org/W2025767020","https://openalex.org/W2028064677","https://openalex.org/W2029914347","https://openalex.org/W2031128803","https://openalex.org/W2038010722","https://openalex.org/W2044710722","https://openalex.org/W2046931787","https://openalex.org/W2051299882","https://openalex.org/W2058317978","https://openalex.org/W2059081487","https://openalex.org/W2060754769","https://openalex.org/W2060997715","https://openalex.org/W2062205749","https://openalex.org/W2064546610","https://openalex.org/W2064864651","https://openalex.org/W2067758724","https://openalex.org/W2072344970","https://openalex.org/W2072646880","https://openalex.org/W2075953654","https://openalex.org/W2076837393","https://openalex.org/W2078496970","https://openalex.org/W2080359390","https://openalex.org/W2087887844","https://openalex.org/W2088366586","https://openalex.org/W2089275594","https://openalex.org/W2091250795","https://openalex.org/W2091388023","https://openalex.org/W2091433391","https://openalex.org/W2094242086","https://openalex.org/W2101491120","https://openalex.org/W2105616599","https://openalex.org/W2105795671","https://openalex.org/W2110169856","https://openalex.org/W2110980460","https://openalex.org/W2113596976","https://openalex.org/W2116068672","https://openalex.org/W2116255409","https://openalex.org/W2116667760","https://openalex.org/W2117812958","https://openalex.org/W2118299459","https://openalex.org/W2119190752","https://openalex.org/W2128103256","https://openalex.org/W2132526669","https://openalex.org/W2134511517","https://openalex.org/W2140086263","https://openalex.org/W2144082513","https://openalex.org/W2146305537","https://openalex.org/W2146995433","https://openalex.org/W2149889831","https://openalex.org/W2151916489","https://openalex.org/W2156530194","https://openalex.org/W2158718550","https://openalex.org/W2166540469","https://openalex.org/W2168524781","https://openalex.org/W2171712530","https://openalex.org/W2195448235","https://openalex.org/W2235121711","https://openalex.org/W2250105806","https://openalex.org/W2269626398","https://openalex.org/W2282389950","https://openalex.org/W2315880158","https://openalex.org/W2315917752","https://openalex.org/W2333668102","https://openalex.org/W2398863832","https://openalex.org/W2406042466","https://openalex.org/W4248627171","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2007299159","https://openalex.org/W3004533848","https://openalex.org/W2188865192","https://openalex.org/W2035546780","https://openalex.org/W232308250","https://openalex.org/W2891076520","https://openalex.org/W4408196350","https://openalex.org/W7220679038","https://openalex.org/W2739694089","https://openalex.org/W2802667829"],"abstract_inverted_index":{"Probiotics":[0],"have":[1,29,88,93],"been":[2,30,89],"defined":[3],"by":[4,153],"The":[5,137],"Food":[6],"Agricultural":[7],"Organization/World":[8],"Health":[9],"Organization":[10],"(FAO/WHO)":[11],"as":[12,47],"\"live":[13],"microorganisms":[14],"which":[15],"when":[16],"administered":[17],"in":[18,34,150],"adequate":[19],"amounts":[20],"confer":[21],"a":[22,48,77],"health":[23],"benefit":[24],"to":[25,73,96],"the":[26,35,42,94],"host.\"":[27],"They":[28],"used":[31],"for":[32,145],"centuries":[33],"form":[36,49],"of":[37,45,50,68,139],"dairy-based":[38],"fermented":[39],"products,":[40],"but":[41],"potential":[43,95],"use":[44,81,138],"probiotics":[46,100,140],"medical":[51,83,155],"nutrition":[52],"therapy":[53],"has":[54],"not":[55],"received":[56],"formal":[57],"recognition.":[58],"A":[59],"detailed":[60],"literature":[61],"review":[62],"(from":[63],"1950":[64],"through":[65],"February":[66],"2004)":[67],"English-language":[69],"articles":[70,75],"was":[71],"undertaken":[72],"find":[74],"showing":[76],"relationship":[78],"between":[79],"probiotic":[80],"and":[82,107,113,135,148],"conditions.":[84,156],"Medical":[85],"conditions":[86],"that":[87],"reportedly":[90],"treated":[91,98],"or":[92],"be":[97,142],"with":[99],"include":[101],"diarrhea,":[102],"gastroenteritis,":[103],"irritable":[104],"bowel":[105,109],"syndrome,":[106],"inflammatory":[108],"disease":[110,112],"(Crohn's":[111],"ulcerative":[114],"colitis),":[115],"cancer,":[116],"depressed":[117],"immune":[118],"function,":[119],"inadequate":[120],"lactase":[121],"digestion,":[122],"infant":[123],"allergies,":[124],"failure-to-thrive,":[125],"hyperlipidemia,":[126],"hepatic":[127],"diseases,":[128],"Helicobacter":[129],"pylori":[130],"infections,":[131,134],"genitourinary":[132],"tract":[133],"others.":[136],"should":[141],"further":[143],"investigated":[144],"possible":[146],"benefits":[147],"side-effects":[149],"patients":[151],"affected":[152],"these":[154]},"counts_by_year":[{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":18},{"year":2020,"cited_by_count":10},{"year":2019,"cited_by_count":14},{"year":2018,"cited_by_count":20},{"year":2017,"cited_by_count":6},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":17},{"year":2013,"cited_by_count":8},{"year":2012,"cited_by_count":14}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
