{"id":"https://openalex.org/W98670528","doi":null,"title":"[Total gastrectomy for gastric cancer: can the type of lymphadenectomy condition the long-term results?].","display_name":"[Total gastrectomy for gastric cancer: can the type of lymphadenectomy condition the long-term results?].","publication_year":2005,"publication_date":"2005-05-01","ids":{"openalex":"https://openalex.org/W98670528","mag":"98670528","pmid":"https://pubmed.ncbi.nlm.nih.gov/16437920"},"language":"it","primary_location":{"id":"pmid:16437920","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16437920","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","raw_type":"English Abstract"},"parent_works":[],"lineage":["https://openalex.org/W98670528"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049825933","display_name":"Natale Di Martino","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I197809005","display_name":"University of Campania \"Luigi Vanvitelli\"","ror":"https://ror.org/02kqnpp86","country_code":"IT","type":"education","lineage":["https://openalex.org/I197809005"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"N Di Martino","raw_affiliation_strings":["VIII Chirturgia Generale e Fisiopatologia Gastroenterologica, Seconda Universit\u00e0 degli Studi, Napoli"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"VIII Chirturgia Generale e Fisiopatologia Gastroenterologica, Seconda Universit\u00e0 degli Studi, Napoli","institution_ids":["https://openalex.org/I197809005"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044298477","display_name":"Giuseppe Izzo","orcid":"https://orcid.org/0000-0003-1412-8702","observed_orcids":["https://orcid.org/0000-0003-1412-8702"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Izzo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108665384","display_name":"Agnese Cosenza","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Cosenza","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091081843","display_name":"Luciano Vicenzo","orcid":"https://orcid.org/0009-0009-5307-8403","observed_orcids":["https://orcid.org/0009-0009-5307-8403"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Vicenzo","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064667938","display_name":"Luigi Monaco","orcid":"https://orcid.org/0000-0001-5324-6731","observed_orcids":["https://orcid.org/0000-0001-5324-6731"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Monaco","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"F Torelli","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F Torelli","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5154769225","display_name":"BASCIOTTI A.","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Basciotti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072870404","display_name":"Antonio Brillantino","orcid":"https://orcid.org/0000-0002-0198-8511","observed_orcids":["https://orcid.org/0000-0002-0198-8511"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Brillantino","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":null,"display_name":"A Marra","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Marra","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3446,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.62854282,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"4","issue":"3","first_page":"S84","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10696","display_name":"Gastric Cancer Management and Outcomes","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gastric-cancer","display_name":"gastric cancer","score":0.9629999995231628},{"id":"https://openalex.org/keywords/total-gastrectomy","display_name":"total gastrectomy","score":0.9959999918937683},{"id":"https://openalex.org/keywords/lymph-node-dissection","display_name":"lymph node dissection","score":0.7720000147819519},{"id":"https://openalex.org/keywords/d2-lymphadenectomy","display_name":"D2 lymph node dissection","score":0.9660000205039978},{"id":"https://openalex.org/keywords/d3-lymphadenectomy","display_name":"D3 lymphadenectomy","score":0.8379999995231628},{"id":"https://openalex.org/keywords/d1-lymphadenectomy","display_name":"D1 lymphadenectomy","score":0.906000018119812},{"id":"https://openalex.org/keywords/gastric-adenocarcinoma","display_name":"gastric adenocarcinoma","score":0.8550000190734863},{"id":"https://openalex.org/keywords/long-term-survival","display_name":"long-term survival","score":0.8309999704360962},{"id":"https://openalex.org/keywords/lymph-node-metastasis","display_name":"lymph node metastasis","score":0.8029999732971191},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.6830000281333923},{"id":"https://openalex.org/keywords/splenectomy","display_name":"splenectomy","score":0.6309999823570251},{"id":"https://openalex.org/keywords/roux-en-y-reconstruction","display_name":"Roux-en-Y reconstruction","score":0.8870000243186951},{"id":"https://openalex.org/keywords/postoperative-morbidity","display_name":"postoperative morbidity","score":0.6200000047683716},{"id":"https://openalex.org/keywords/resection-rate","display_name":"resection rate","score":0.3799999952316284}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8781222105026245},{"id":"https://openalex.org/C2780470880","wikidata":"https://www.wikidata.org/wiki/Q827390","display_name":"Gastrectomy","level":3,"score":0.8435279130935669},{"id":"https://openalex.org/C2780824555","wikidata":"https://www.wikidata.org/wiki/Q1809305","display_name":"Lymphadenectomy","level":3,"score":0.8195968866348267},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.6496491432189941},{"id":"https://openalex.org/C8443397","wikidata":"https://www.wikidata.org/wiki/Q15177","display_name":"Anastomosis","level":2,"score":0.5605918765068054},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.5131602883338928},{"id":"https://openalex.org/C2775862295","wikidata":"https://www.wikidata.org/wiki/Q2660911","display_name":"Dissection (medical)","level":2,"score":0.5069766044616699},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.4785107672214508},{"id":"https://openalex.org/C2776309230","wikidata":"https://www.wikidata.org/wiki/Q580383","display_name":"Splenectomy","level":3,"score":0.4767383337020874},{"id":"https://openalex.org/C2781182431","wikidata":"https://www.wikidata.org/wiki/Q356033","display_name":"Adenocarcinoma","level":3,"score":0.44094645977020264},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.413653165102005},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.4032200574874878},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.37975773215293884},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3487086296081543},{"id":"https://openalex.org/C2780931953","wikidata":"https://www.wikidata.org/wiki/Q9371","display_name":"Spleen","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D005743","descriptor_name":"Gastrectomy","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008197","descriptor_name":"Lymph Node Excision","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D013274","descriptor_name":"Stomach Neoplasms","qualifier_ui":"Q000601","qualifier_name":"surgery","is_major_topic":true},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015996","descriptor_name":"Survival Rate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:16437920","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16437920","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.]","raw_type":"English Abstract"},{"id":"pmh:oai:iris.unicampania.it:11591/190302","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11591/190302","pdf_url":null,"source":{"id":"https://openalex.org/S7407055255","display_name":"Archivio Istituzionale della Ricerca - Universit\u00e0 degli Studi della Campania \"Luigi Vanvitelli\"","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1968034061","https://openalex.org/W2462282366","https://openalex.org/W2419569290","https://openalex.org/W2290830631","https://openalex.org/W3192459555","https://openalex.org/W2071958164","https://openalex.org/W7220681584","https://openalex.org/W1981491936","https://openalex.org/W2018457227"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Gastric":[1,244],"cancer":[2,105,265,569],"is":[3,13,42,50,127,533,586,610],"the":[4,10,15,35,59,66,70,79,97,103,107,110,119,130,134,146,150,154,159,164,211,239,264,270,277,280,321,327,355,362,367,372,376,381,386,391,401,405,413,433,440,446,450,472,475,478,525,528,540,547,557,590,600,611,617,620,637,643,645,652],"second":[5],"tumor":[6],"for":[7,142,243,354,361,366,371,375,380,550,605,616,624],"frequency":[8],"in":[9,21,34,69,102,133,258,390,404,432,449,477,488,497,505,510,527,556,599,636],"world.":[11],"Surgery":[12],"still":[14,86,534],"only":[16],"curative":[17],"treatment.":[18],"Good":[19],"results":[20,147],"terms":[22],"of":[23,40,82,96,112,124,182,192,269,279,326,427,474,524,542,573,592,602,619,648],"long":[24,519,553,631],"distance":[25,520,554,632],"survival,":[26,633],"postoperative":[27],"morbidity":[28],"and":[29,45,48,106,109,153,201,218,256,311,378,429,435,508,522,571,628],"mortality":[30,341],"have":[31],"been":[32,273],"achieved":[33],"last":[36],"years.":[37],"The":[38,62,122,267,283,314,350,467,516],"extension":[39,268,473,523],"lymphadenectomy":[41,54,132,152,271,453,476,495,526,545,609],"an":[43],"important":[44,99],"discussed":[46],"matter":[47],"it":[49],"not":[51],"clear":[52],"if":[53],"may":[55],"contribute":[56],"to":[57,72,93,117,128,158,172,248,276,484,502,613],"improve":[58],"surgical":[60],"results.":[61],"Japanese":[63,240],"surgeons":[64],"were":[65,137,188,213,285,332],"first":[67],"ones,":[68],"60's,":[71],"introduce":[73],"a":[74,219,235,294,335,425,493,543,551,565,596,625,629],"D2-D3":[75],"extended":[76],"lymphadenectomy,":[77,418],"but":[78,634],"real":[80],"benefits":[81],"this":[83,125,208,603,606],"technique":[84,612],"are":[85,115,251,581],"being":[87,535],"discussed.":[88,536],"Indeed":[89],"lymphonodal":[90,165,408,481],"metastasis":[91,395,409,482,594],"seem":[92],"be":[94,485,614],"one":[95,197],"most":[98],"prognostic":[100],"factors":[101],"gastric":[104,143,179,531,560,568,621],"level":[108,278],"number":[111,572,647],"metastatic":[113],"nodes":[114,250,580],"useful":[116],"predict":[118],"patients'":[120],"survival.":[121],"aim":[123],"study":[126],"value":[129,320],"D2":[131,304,434,454,494,608],"patients":[135,177,184,194,212,231,284,292,302,308,329,392,406,414,451,479,490,529,558],"who":[136,415,491],"treated":[138,185,195,214],"with":[139,149,163,178,215,297,334,407,452,480,530,559,583],"total":[140,216,295],"gastrectomy":[141,217,296],"adenocarcinoma,":[144,622],"comparing":[145],"both":[148,501,623],"D1":[151,298,417,456,503],"D3-D4,":[155],"paying":[156],"attention":[157],"survival":[160,322,346,353,389,419,447,468,521,555],"rates":[161],"related":[162],"dissection.":[166],"PATIENTS":[167],"AND":[168],"METHOD:":[169],"From":[170],"1998":[171],"2004,":[173],"we":[174,232,316,423],"studied":[175],"87":[176],"cancer.":[180,561],"Out":[181,191,325],"78":[183,328],"surgically,":[186,196],"9":[187],"judged":[189],"unresectable.":[190],"69":[193,331],"died":[198],"before":[199],"surgery":[200],"so":[202],"he":[203],"was":[204,342,347,358,396,420,459],"put":[205],"away":[206],"by":[207,223],"study.":[209],"All":[210],"GI":[220],"tract":[221],"reconstruction":[222],"Roux's":[224],"Y":[225],"termino-lateral":[226],"esophageal-jejunal":[227],"anastomosis.":[228],"In":[229,384,412,439],"20":[230],"also":[233],"made":[234],"splenectomy.":[236],"We":[237],"followed":[238],"Research":[241],"Society":[242],"Cancer":[245],"guidelines,":[246],"according":[247,275],"which":[249,640],"gathered":[252],"into":[253,287],"16":[254],"levels":[255],"divided":[257,286],"4":[259],"groups":[260],"(N1-N4)":[261],"depending":[262],"on":[263,471],"localization.":[266],"has":[272,595],"classified":[274],"removed":[281],"nods.":[282],"3":[288],"groups.":[289],"First":[290],"group:":[291,301,307],"undergone":[293,303,309],"lymphadenectomy.":[299,305,313,514],"Second":[300],"Third":[306],"D3":[310],"D4":[312],"data":[315],"obtained":[317,403,424],"let":[318],"us":[319],"rate.":[323],"RESULTS:":[324],"treated,":[330],"resected":[333],"88.5%":[336],"resection":[337],"rate":[338,448,469],"(69/78).":[339],"Perioperatory":[340],"1.4%":[343],"(1/69).":[344],"Global":[345],"53.8%":[348],"(44/68).":[349],"5":[351,387,498,511],"years":[352,388],"Ia":[356],"stage":[357],"82.6%,":[359],"89.3%":[360],"Ib":[363],"stage,":[364,369],"67.8%":[365],"II":[368],"56.6%":[370],"IIIa,":[373],"16.8%":[374],"IIIb":[377],"0%":[379,462],"IV":[382],"stage.":[383],"addition":[385],"without":[393],"lymphnodal":[394],"79%,":[397],"much":[398,486],"higher":[399,487],"than":[400,578],"30.6%":[402],"(p":[410,437,465],"<0.0001).":[411,466],"underwent":[416,492],"73.4%,":[421],"while":[422],"result":[426],"70.4%":[428],"13.8%":[430],"respectively":[431],"D3-D4":[436,458,513],"<0.05).":[438],"advanced":[441,638],"stages":[442],"(IIIa,":[443],"IIIb,":[444],"IV),":[445],"vs":[455,457,461,463],"38.9%":[460],"36.3%":[464],"based":[470],"resulted":[483],"those":[489],"(43.5%":[496],"years)":[499,512],"compared":[500],"(0%":[504],"6":[506],"months)":[507],"(29.5%":[509],"CONCLUSIONS:":[515],"relation":[517],"between":[518,567],"adenocarcinoma":[532],"Different":[537],"studies":[538,563],"show":[539],"importance":[541],"careful":[544],"as":[546],"main":[548],"mean":[549],"better":[552,630],"Other":[562],"showed":[564],"link":[566],"prognosis":[570,585,601],"positive":[574],"nodes.":[575],"If":[576],"more":[577],"7-8":[579],"affected":[582],"metastasis,":[584],"usually":[587],"poor.":[588],"Therefore":[589],"presence":[591],"nod":[593],"negative":[597],"influence":[598],"tumor;":[604],"reason":[607],"used":[615],"treatment":[618],"good":[626],"staging":[627],"particularly":[635],"cancers":[639],"are,":[641],"at":[642],"moment,":[644],"highest":[646],"cases":[649],"that":[650],"reach":[651],"surgeon's":[653],"attention.":[654]},"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-14T11:04:58.165337","created_date":"2016-06-24T00:00:00"}