{"id":"https://openalex.org/W981670958","doi":null,"title":"Applied clinical neuroimaging in cerebral amyloid angiopathy and spontaneous intracerebral haemorrhage","display_name":"Applied clinical neuroimaging in cerebral amyloid angiopathy and spontaneous intracerebral haemorrhage","publication_year":2015,"publication_date":"2015-01-28","ids":{"openalex":"https://openalex.org/W981670958","mag":"981670958"},"language":"en","primary_location":{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1461023","doi":null,"is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/1461023/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Doctoral thesis, UCL (University College London).","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5001829677","display_name":"Andreas Charidimou","orcid":"https://orcid.org/0000-0001-5891-337X","observed_orcids":["https://orcid.org/0000-0001-5891-337X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Andreas Charidimou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5001829677"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13648","display_name":"Cerebrovascular and genetic disorders","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13481","display_name":"Neurological diseases and metabolism","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cerebral-amyloid-angiopathy","display_name":"cerebral amyloid angiopathy","score":0.9980000257492065},{"id":"https://openalex.org/keywords/spontaneous-intracerebral-hemorrhage","display_name":"spontaneous intracerebral hemorrhage","score":0.972000002861023},{"id":"https://openalex.org/keywords/neuroimaging-biomarkers","display_name":"neuroimaging biomarkers","score":0.8539999723434448},{"id":"https://openalex.org/keywords/cortical-superficial-siderosis","display_name":"cortical superficial siderosis","score":0.7770000100135803},{"id":"https://openalex.org/keywords/perivascular-spaces","display_name":"perivascular spaces","score":0.9070000052452087},{"id":"https://openalex.org/keywords/cerebral-small-vessel-disease","display_name":"cerebral small vessel disease","score":0.8420000076293945},{"id":"https://openalex.org/keywords/cerebral-microbleeds","display_name":"cerebral microbleeds","score":0.9039999842643738},{"id":"https://openalex.org/keywords/amyloid-beta-deposition","display_name":"amyloid-beta deposition","score":0.781000018119812},{"id":"https://openalex.org/keywords/disease-phenotype","display_name":"disease phenotypes","score":0.7509999871253967},{"id":"https://openalex.org/keywords/genetic-variants","display_name":"genetic variants","score":0.3370000123977661},{"id":"https://openalex.org/keywords/magnetic-resonance-imaging","display_name":"magnetic resonance imaging","score":0.3050000071525574}],"concepts":[{"id":"https://openalex.org/C2777790613","wikidata":"https://www.wikidata.org/wiki/Q191562","display_name":"Cerebral amyloid angiopathy","level":4,"score":0.9764233827590942},{"id":"https://openalex.org/C58693492","wikidata":"https://www.wikidata.org/wiki/Q551875","display_name":"Neuroimaging","level":2,"score":0.7567620277404785},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6871639490127563},{"id":"https://openalex.org/C2779703115","wikidata":"https://www.wikidata.org/wiki/Q539702","display_name":"Angiopathy","level":3,"score":0.6727737784385681},{"id":"https://openalex.org/C2780860705","wikidata":"https://www.wikidata.org/wiki/Q7643329","display_name":"Superficial siderosis","level":5,"score":0.6676256656646729},{"id":"https://openalex.org/C2777799939","wikidata":"https://www.wikidata.org/wiki/Q1711381","display_name":"Perivascular space","level":2,"score":0.6385934352874756},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.5369294881820679},{"id":"https://openalex.org/C2777633098","wikidata":"https://www.wikidata.org/wiki/Q2736051","display_name":"Amyloid (mycology)","level":2,"score":0.4838082194328308},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4282294511795044},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.39765217900276184},{"id":"https://openalex.org/C2779483572","wikidata":"https://www.wikidata.org/wiki/Q83030","display_name":"Dementia","level":3,"score":0.3722410798072815},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.206184983253479},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.0686870813369751},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.06533479690551758},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:eprints.ucl.ac.uk.OAI2:1461023","doi":null,"is_oa":false,"landing_page_url":"https://discovery.ucl.ac.uk/id/eprint/1461023/","pdf_url":null,"source":{"id":"https://openalex.org/S4306400024","display_name":"UCL Discovery (University College London)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45129253","host_organization_name":"University College London","host_organization_lineage":["https://openalex.org/I45129253"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Doctoral thesis, UCL (University College London).","raw_type":"Thesis"},{"id":"mag:981670958","doi":null,"is_oa":false,"landing_page_url":"http://discovery.ucl.ac.uk/1461023/","pdf_url":null,"source":{"id":"https://openalex.org/S4306508231","display_name":"Doctoral thesis, UCL (University College London).","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Doctoral thesis, UCL (University College London).","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.98580002784729,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":366,"referenced_works":["https://openalex.org/W4771264","https://openalex.org/W122185080","https://openalex.org/W148771838","https://openalex.org/W194511638","https://openalex.org/W1489506413","https://openalex.org/W1494682338","https://openalex.org/W1496503766","https://openalex.org/W1498589284","https://openalex.org/W1514000757","https://openalex.org/W1532446175","https://openalex.org/W1544338382","https://openalex.org/W1546258268","https://openalex.org/W1547738966","https://openalex.org/W1560495377","https://openalex.org/W1594119953","https://openalex.org/W1595360136","https://openalex.org/W1603244154","https://openalex.org/W1606852336","https://openalex.org/W1618236677","https://openalex.org/W1645365656","https://openalex.org/W1671478575","https://openalex.org/W1770880387","https://openalex.org/W1822779864","https://openalex.org/W1870043354","https://openalex.org/W1905113423","https://openalex.org/W1908308221","https://openalex.org/W1940935917","https://openalex.org/W1964251512","https://openalex.org/W1964793333","https://openalex.org/W1967183808","https://openalex.org/W1968954730","https://openalex.org/W1969055182","https://openalex.org/W1969642241","https://openalex.org/W1969713959","https://openalex.org/W1970381878","https://openalex.org/W1970928383","https://openalex.org/W1972186270","https://openalex.org/W1974339392","https://openalex.org/W1974444040","https://openalex.org/W1974893560","https://openalex.org/W1974993173","https://openalex.org/W1975506997","https://openalex.org/W1975923957","https://openalex.org/W1976419330","https://openalex.org/W1976545954","https://openalex.org/W1979131000","https://openalex.org/W1979221664","https://openalex.org/W1979243823","https://openalex.org/W1979415323","https://openalex.org/W1979423827","https://openalex.org/W1979492588","https://openalex.org/W1979843610","https://openalex.org/W1981666590","https://openalex.org/W1981711337","https://openalex.org/W1982206682","https://openalex.org/W1982245010","https://openalex.org/W1982490583","https://openalex.org/W1982902952","https://openalex.org/W1983926694","https://openalex.org/W1983933902","https://openalex.org/W1985093052","https://openalex.org/W1985477573","https://openalex.org/W1992608632","https://openalex.org/W1993102117","https://openalex.org/W1994170291","https://openalex.org/W1994183414","https://openalex.org/W1996003447","https://openalex.org/W1997600737","https://openalex.org/W1998616945","https://openalex.org/W1998801224","https://openalex.org/W2000233513","https://openalex.org/W2000291174","https://openalex.org/W2000388025","https://openalex.org/W2000917982","https://openalex.org/W2001462666","https://openalex.org/W2002061584","https://openalex.org/W2002172383","https://openalex.org/W2005251537","https://openalex.org/W2005257697","https://openalex.org/W2006534012","https://openalex.org/W2006756307","https://openalex.org/W2007586650","https://openalex.org/W2007847631","https://openalex.org/W2007925818","https://openalex.org/W2007951064","https://openalex.org/W2008706768","https://openalex.org/W2010432189","https://openalex.org/W2010925904","https://openalex.org/W2011058648","https://openalex.org/W2011991444","https://openalex.org/W2012291518","https://openalex.org/W2012304562","https://openalex.org/W2012403261","https://openalex.org/W2012644075","https://openalex.org/W2013520583","https://openalex.org/W2014889602","https://openalex.org/W2015010735","https://openalex.org/W2017302232","https://openalex.org/W2017994475","https://openalex.org/W2018721445","https://openalex.org/W2018773958","https://openalex.org/W2019718390","https://openalex.org/W2020068741","https://openalex.org/W2020240430","https://openalex.org/W2020847830","https://openalex.org/W2021648195","https://openalex.org/W2022298496","https://openalex.org/W2022459144","https://openalex.org/W2023092313","https://openalex.org/W2023322393","https://openalex.org/W2023726085","https://openalex.org/W2024115648","https://openalex.org/W2024116918","https://openalex.org/W2025313184","https://openalex.org/W2027394925","https://openalex.org/W2027688413","https://openalex.org/W2027781675","https://openalex.org/W2028053632","https://openalex.org/W2028084402","https://openalex.org/W2029485104","https://openalex.org/W2029676716","https://openalex.org/W2030827970","https://openalex.org/W2031055635","https://openalex.org/W2032061707","https://openalex.org/W2032920422","https://openalex.org/W2035439084","https://openalex.org/W2035828045","https://openalex.org/W2036100058","https://openalex.org/W2036920551","https://openalex.org/W2037045923","https://openalex.org/W2037262598","https://openalex.org/W2038187923","https://openalex.org/W2038703154","https://openalex.org/W2039598751","https://openalex.org/W2040490831","https://openalex.org/W2041396523","https://openalex.org/W2042658886","https://openalex.org/W2043595836","https://openalex.org/W2043842616","https://openalex.org/W2044372075","https://openalex.org/W2044920476","https://openalex.org/W2045508263","https://openalex.org/W2047316865","https://openalex.org/W2047645801","https://openalex.org/W2047857011","https://openalex.org/W2048558011","https://openalex.org/W2049743711","https://openalex.org/W2050282012","https://openalex.org/W2051182982","https://openalex.org/W2051202763","https://openalex.org/W2052815231","https://openalex.org/W2052987015","https://openalex.org/W2053562788","https://openalex.org/W2054220071","https://openalex.org/W2054488837","https://openalex.org/W2054931992","https://openalex.org/W2060215608","https://openalex.org/W2061820841","https://openalex.org/W2062941737","https://openalex.org/W2063069607","https://openalex.org/W2064154600","https://openalex.org/W2064295262","https://openalex.org/W2065904500","https://openalex.org/W2067314578","https://openalex.org/W2067766876","https://openalex.org/W2068394373","https://openalex.org/W2068502124","https://openalex.org/W2068808615","https://openalex.org/W2070857646","https://openalex.org/W2072957914","https://openalex.org/W2073495172","https://openalex.org/W2073566962","https://openalex.org/W2073589898","https://openalex.org/W2073635779","https://openalex.org/W2074782909","https://openalex.org/W2075078231","https://openalex.org/W2075091034","https://openalex.org/W2075135948","https://openalex.org/W2075348467","https://openalex.org/W2076021167","https://openalex.org/W2076215149","https://openalex.org/W2076779801","https://openalex.org/W2077986954","https://openalex.org/W2079178395","https://openalex.org/W2079492580","https://openalex.org/W2079613093","https://openalex.org/W2080269802","https://openalex.org/W2080369823","https://openalex.org/W2081061369","https://openalex.org/W2081182167","https://openalex.org/W2081401129","https://openalex.org/W2081547922","https://openalex.org/W2081598046","https://openalex.org/W2081876799","https://openalex.org/W2082496690","https://openalex.org/W2082826552","https://openalex.org/W2083839210","https://openalex.org/W2084439196","https://openalex.org/W2084484659","https://openalex.org/W2084603409","https://openalex.org/W2084670317","https://openalex.org/W2084675121","https://openalex.org/W2085138234","https://openalex.org/W2086572083","https://openalex.org/W2087371306","https://openalex.org/W2087529125","https://openalex.org/W2087534096","https://openalex.org/W2087665398","https://openalex.org/W2088339033","https://openalex.org/W2088802425","https://openalex.org/W2090723320","https://openalex.org/W2090774331","https://openalex.org/W2091189732","https://openalex.org/W2092675951","https://openalex.org/W2092863674","https://openalex.org/W2095411169","https://openalex.org/W2095750451","https://openalex.org/W2096246254","https://openalex.org/W2097036998","https://openalex.org/W2098819343","https://openalex.org/W2100545541","https://openalex.org/W2101286322","https://openalex.org/W2101620652","https://openalex.org/W2102124101","https://openalex.org/W2102509688","https://openalex.org/W2102669626","https://openalex.org/W2103368759","https://openalex.org/W2103473142","https://openalex.org/W2103480964","https://openalex.org/W2104080769","https://openalex.org/W2104901197","https://openalex.org/W2106054034","https://openalex.org/W2106638890","https://openalex.org/W2107328434","https://openalex.org/W2107431414","https://openalex.org/W2107806963","https://openalex.org/W2108012929","https://openalex.org/W2110317256","https://openalex.org/W2111332142","https://openalex.org/W2112161237","https://openalex.org/W2112435159","https://openalex.org/W2113705748","https://openalex.org/W2113711307","https://openalex.org/W2113770731","https://openalex.org/W2114214167","https://openalex.org/W2114553926","https://openalex.org/W2114577833","https://openalex.org/W2115340065","https://openalex.org/W2115505196","https://openalex.org/W2116163670","https://openalex.org/W2116896297","https://openalex.org/W2117130548","https://openalex.org/W2117441853","https://openalex.org/W2117915018","https://openalex.org/W2118753807","https://openalex.org/W2119104244","https://openalex.org/W2119730268","https://openalex.org/W2120210755","https://openalex.org/W2121101037","https://openalex.org/W2121820797","https://openalex.org/W2122477279","https://openalex.org/W2122843800","https://openalex.org/W2123168944","https://openalex.org/W2123199210","https://openalex.org/W2123639852","https://openalex.org/W2124077054","https://openalex.org/W2124210220","https://openalex.org/W2124305917","https://openalex.org/W2125469441","https://openalex.org/W2127707745","https://openalex.org/W2128008772","https://openalex.org/W2128178138","https://openalex.org/W2128278384","https://openalex.org/W2128757133","https://openalex.org/W2130256616","https://openalex.org/W2131943911","https://openalex.org/W2132220200","https://openalex.org/W2132998463","https://openalex.org/W2135148614","https://openalex.org/W2135182187","https://openalex.org/W2135705524","https://openalex.org/W2136489990","https://openalex.org/W2136587148","https://openalex.org/W2137091415","https://openalex.org/W2138244817","https://openalex.org/W2138885882","https://openalex.org/W2138994517","https://openalex.org/W2139667731","https://openalex.org/W2139776416","https://openalex.org/W2140260680","https://openalex.org/W2140621953","https://openalex.org/W2141499686","https://openalex.org/W2142635793","https://openalex.org/W2142679355","https://openalex.org/W2143238511","https://openalex.org/W2144913309","https://openalex.org/W2144971762","https://openalex.org/W2145396188","https://openalex.org/W2146995714","https://openalex.org/W2147457257","https://openalex.org/W2148035614","https://openalex.org/W2148330009","https://openalex.org/W2148568506","https://openalex.org/W2148954037","https://openalex.org/W2149722331","https://openalex.org/W2151445100","https://openalex.org/W2151735381","https://openalex.org/W2151863209","https://openalex.org/W2152223730","https://openalex.org/W2153163920","https://openalex.org/W2154243390","https://openalex.org/W2154297192","https://openalex.org/W2154350726","https://openalex.org/W2155270826","https://openalex.org/W2155894782","https://openalex.org/W2156098321","https://openalex.org/W2156305175","https://openalex.org/W2156770250","https://openalex.org/W2158324125","https://openalex.org/W2158742097","https://openalex.org/W2159081727","https://openalex.org/W2159507601","https://openalex.org/W2159823093","https://openalex.org/W2160509359","https://openalex.org/W2160698218","https://openalex.org/W2160871111","https://openalex.org/W2160943597","https://openalex.org/W2161079228","https://openalex.org/W2162611043","https://openalex.org/W2162794669","https://openalex.org/W2163570199","https://openalex.org/W2164902669","https://openalex.org/W2164972283","https://openalex.org/W2165920141","https://openalex.org/W2166734331","https://openalex.org/W2167389139","https://openalex.org/W2167691539","https://openalex.org/W2167720733","https://openalex.org/W2167840686","https://openalex.org/W2168338439","https://openalex.org/W2168582544","https://openalex.org/W2168934316","https://openalex.org/W2169748964","https://openalex.org/W2169851819","https://openalex.org/W2170765765","https://openalex.org/W2171264766","https://openalex.org/W2172053191","https://openalex.org/W2172180906","https://openalex.org/W2223656268","https://openalex.org/W2318037607","https://openalex.org/W2331217083","https://openalex.org/W2333149577","https://openalex.org/W2342012891","https://openalex.org/W2346898895","https://openalex.org/W2405336736","https://openalex.org/W2418219273","https://openalex.org/W2418374537","https://openalex.org/W2443205144","https://openalex.org/W2463189234","https://openalex.org/W2491981176","https://openalex.org/W2527609605","https://openalex.org/W2599076725","https://openalex.org/W3146362844","https://openalex.org/W3171831654","https://openalex.org/W4237978768","https://openalex.org/W7122649126"],"related_works":["https://openalex.org/W2148035614","https://openalex.org/W2985056992","https://openalex.org/W7024627821","https://openalex.org/W2990681491","https://openalex.org/W1981666590","https://openalex.org/W2084967332","https://openalex.org/W6980521011","https://openalex.org/W3146362844","https://openalex.org/W4386223934","https://openalex.org/W1993973315"],"abstract_inverted_index":{"Sporadic":[0],"cerebral":[1,56,84,151,181,205,222,258],"amyloid":[2,27,57,152,182,206,223],"angiopathy":[3,28],"is":[4,35,50,94,135,155,263,277],"a":[5,36,52,158,176,188,198,201,214,285],"common":[6,37],"small":[7,13,218],"vessel":[8,219],"disease":[9,73,220,247],"that":[10],"preferentially":[11],"involves":[12],"cortical":[14,185],"and":[15,34,38,46,86,143,167,200,221,229,238,242,255,273],"leptomeningeal":[16],"arteries":[17],"due":[18],"to":[19,70,79,136,280],"progressive":[20],"amyloid-\u03b2":[21],"deposition":[22],"in":[23,31,55,75,148,193,232,284],"their":[24],"walls.":[25],"Cerebral":[26],"occurs":[29],"frequently":[30],"elderly":[32],"people,":[33],"important":[39,98],"cause":[40],"of":[41,83,90,102,120,125,131,160,170,204,217,257,269],"symptomatic":[42],"lobar":[43],"intracerebral":[44,240],"haemorrhage":[45,241],"cognitive":[47],"impairment.":[48],"There":[49],"currently":[51],"growing":[53],"interest":[54],"angiopathy,":[58],"at":[59],"least":[60],"partly":[61],"thanks":[62],"neuroimaging,":[63],"which":[64],"now":[65,108],"allows":[66],"an":[67,96,266],"unprecedented":[68],"ability":[69],"investigate":[71],"the":[72,114,123,165,194,250,253],"dynamics":[74],"vivo":[76],"using":[77],"MRI":[78,261],"reveal":[80],"complex":[81],"patterns":[82],"bleeding":[85,192],"ischaemia.":[87],"The":[88,128],"detection":[89],"CAA":[91,236],"during":[92],"life":[93],"becoming":[95],"increasingly":[97],"challenge,":[99],"since":[100],"approaches":[101],"prevention":[103],"or":[104],"treatment":[105],"(disease-modification)":[106],"are":[107],"emerging":[109],"as":[110,175,196,213],"realistic":[111],"possibilities.":[112],"Determining":[113],"most":[115],"promising":[116],"treatments":[117],"requires":[118],"development":[119],"reliable":[121],"biomarkers,":[122],"goal":[124],"my":[126],"research.":[127],"main":[129],"objective":[130],"this":[132,275],"PhD":[133],"thesis":[134],"provide":[137],"new":[138,215],"insights":[139],"into":[140],"potential":[141,177,226],"clinical":[142,145,166,178],"applied":[144],"neuroimaging":[146,228],"biomarkers":[147],"patients":[149,233],"with":[150,234,237,265],"angiopathy.":[153],"This":[154],"accomplished":[156],"by":[157],"portfolio":[159],"research":[161],"studies":[162],"investigating:":[163],"(a)":[164],"radiological":[168],"spectrum":[169],"transient":[171],"focal":[172],"neurological":[173],"episodes":[174],"clue":[179],"for":[180,245],"angiopathy;":[183,207,224],"(b)":[184],"superficial":[186],"siderosis,":[187],"distinct":[189],"pattern":[190],"on":[191,260],"brain,":[195],"both":[197],"diagnostic":[199],"prognostic":[202],"marker":[203,216],"(c)":[208],"MRI-visible":[209],"perivascular":[210],"spaces":[211],"topography,":[212],"(d)":[225],"pathological,":[227],"genetic":[230],"differences":[231],"pathology-proven":[235],"without":[239],"presents":[243],"evidence":[244,251],"different":[246,278],"phenotypes;":[248],"(e)":[249],"whether":[252],"presence":[254],"burden":[256],"microbleeds":[259],"scans":[262],"associated":[264],"increased":[267],"risk":[268,276],"recurrent":[270],"spontaneous":[271],"ICH,":[272],"if":[274],"according":[279],"MRI-defined":[281],"microangiopathy":[282],"subtype,":[283],"meta-analysis.":[286]},"counts_by_year":[{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}