{"id":"https://openalex.org/W98038714","doi":null,"title":"Expression of mast-cell-specific proteases in tissues of mice studied by in situ hybridization.","display_name":"Expression of mast-cell-specific proteases in tissues of mice studied by in situ hybridization.","publication_year":1997,"publication_date":"1997-04-01","ids":{"openalex":"https://openalex.org/W98038714","mag":"98038714","pmid":"https://pubmed.ncbi.nlm.nih.gov/9094993","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1858158"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:1532897","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1858158","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1858158","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016068373","display_name":"Tomoko Jippo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210155576","display_name":"Osaka University Hospital","ror":"https://ror.org/05rnn8t74","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210155576","https://openalex.org/I98285908"]},{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T Jippo","raw_affiliation_strings":["Department of Pathology, Osaka University Medical School, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Osaka University Medical School, Japan","institution_ids":["https://openalex.org/I4210155576","https://openalex.org/I98285908"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056830100","display_name":"Kumiko Tsujino","orcid":"https://orcid.org/0000-0001-8493-5441","observed_orcids":["https://orcid.org/0000-0001-8493-5441"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Tsujino","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5041730131","display_name":"H M Kim","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H M Kim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113469860","display_name":"Dae-Ki Kim","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D K Kim","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000855662","display_name":"YOUNG MI LEE","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y M Lee","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005443263","display_name":"Yukifumi Nawa","orcid":"https://orcid.org/0000-0002-0206-5196","observed_orcids":["https://orcid.org/0000-0002-0206-5196"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y Nawa","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5111447872","display_name":"Yukihiko Kitamura","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Y Kitamura","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.522,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.81133011,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"150","issue":"4","first_page":"1373","last_page":"82"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mast-cells","display_name":"mast cells","score":0.8759999871253967},{"id":"https://openalex.org/keywords/mast-cell-proteases","display_name":"mast cell proteases","score":0.8230000138282776},{"id":"https://openalex.org/keywords/carboxypeptidase-a","display_name":"carboxypeptidase A","score":0.9459999799728394},{"id":"https://openalex.org/keywords/mrna-expression","display_name":"mRNA expression","score":0.5690000057220459},{"id":"https://openalex.org/keywords/gastric-mucosa","display_name":"gastric mucosa","score":0.7979999780654907},{"id":"https://openalex.org/keywords/muscularis-propria","display_name":"muscularis propria","score":0.9409999847412109},{"id":"https://openalex.org/keywords/helminth-infection","display_name":"helminthiasis","score":0.7490000128746033},{"id":"https://openalex.org/keywords/w-wv-mice","display_name":"W/Wv mice","score":0.6209999918937683},{"id":"https://openalex.org/keywords/strain-specificity","display_name":"strain specificity","score":0.6679999828338623},{"id":"https://openalex.org/keywords/peritoneal-mast-cells","display_name":"peritoneal mast cells","score":0.8479999899864197},{"id":"https://openalex.org/keywords/tissue-specificity","display_name":"tissue specificity","score":0.5860000252723694}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8244693875312805},{"id":"https://openalex.org/C2779726688","wikidata":"https://www.wikidata.org/wiki/Q191989","display_name":"Mast cell","level":2,"score":0.7881287336349487},{"id":"https://openalex.org/C81439078","wikidata":"https://www.wikidata.org/wiki/Q2304142","display_name":"In situ hybridization","level":4,"score":0.601750373840332},{"id":"https://openalex.org/C105580179","wikidata":"https://www.wikidata.org/wiki/Q188928","display_name":"Messenger RNA","level":3,"score":0.4764278829097748},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.46693697571754456},{"id":"https://openalex.org/C2779422922","wikidata":"https://www.wikidata.org/wiki/Q1029907","display_name":"Stomach","level":2,"score":0.42943286895751953},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.38158926367759705},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.3331991136074066},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.08182224631309509},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.06264418363571167},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005753","descriptor_name":"Gastric Mucosa","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D005753","descriptor_name":"Gastric Mucosa","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008407","descriptor_name":"Mast Cells","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D008407","descriptor_name":"Mast Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D008407","descriptor_name":"Mast Cells","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D008407","descriptor_name":"Mast Cells","qualifier_ui":"Q000637","qualifier_name":"transplantation","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008817","descriptor_name":"Mice, Mutant Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010529","descriptor_name":"Peritoneal Cavity","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D010641","descriptor_name":"Phenotype","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012333","descriptor_name":"RNA, Messenger","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D012697","descriptor_name":"Serine Endopeptidases","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":true},{"descriptor_ui":"D012697","descriptor_name":"Serine Endopeptidases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D017403","descriptor_name":"In Situ Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053818","descriptor_name":"Chymases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:1532897","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1858158","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:1858158","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1858158","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Pathol","raw_type":"Text"},{"id":"pmid:9094993","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9094993","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of pathology","raw_type":"Journal Article"},{"id":"mag:98038714","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9094993","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:1532897","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1858158","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.6240000128746033,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":39,"referenced_works":["https://openalex.org/W146067998","https://openalex.org/W222360795","https://openalex.org/W1468755370","https://openalex.org/W1483586790","https://openalex.org/W1505318371","https://openalex.org/W1516392471","https://openalex.org/W1528764883","https://openalex.org/W1538316034","https://openalex.org/W1550422318","https://openalex.org/W1551914341","https://openalex.org/W1574017432","https://openalex.org/W1586285458","https://openalex.org/W1630458667","https://openalex.org/W1636878974","https://openalex.org/W1657207959","https://openalex.org/W1975083428","https://openalex.org/W2026631220","https://openalex.org/W2040961976","https://openalex.org/W2052013542","https://openalex.org/W2062123186","https://openalex.org/W2065584207","https://openalex.org/W2086167824","https://openalex.org/W2102720324","https://openalex.org/W2118420320","https://openalex.org/W2123595678","https://openalex.org/W2134860029","https://openalex.org/W2143658570","https://openalex.org/W2147326175","https://openalex.org/W2150403127","https://openalex.org/W2153928526","https://openalex.org/W2162149799","https://openalex.org/W2162384753","https://openalex.org/W2163916023","https://openalex.org/W2164071821","https://openalex.org/W2201480410","https://openalex.org/W2231494321","https://openalex.org/W2246115479","https://openalex.org/W2258506980","https://openalex.org/W2297496700"],"related_works":["https://openalex.org/W2045901940","https://openalex.org/W2052013542","https://openalex.org/W2006932238","https://openalex.org/W2023282174","https://openalex.org/W2021011794","https://openalex.org/W2163916023","https://openalex.org/W1917156299","https://openalex.org/W2061099782","https://openalex.org/W2091530608","https://openalex.org/W1879189053"],"abstract_inverted_index":{"The":[0,74,202,249],"protease":[1,18,278],"mRNA":[2,20,111,129,189,204,232],"expression":[3,112,233,279],"phenotype":[4,234],"of":[5,30,33,51,59,76,94,104,117,123,136,166,183,199,246,263],"individual":[6],"mast":[7,16,24,45,62,80,88,118,121,153,168,178,181,223,264],"cells":[8,25,46,63,89,122,142,154,169,182,224,265],"was":[9,21],"studied":[10],"by":[11,23,44,87,114],"in":[12,27,47,56,65,90,145,157,212,238],"situ":[13],"hybridization.":[14],"Mouse":[15],"cell":[17,81],"(MMCP)-2":[19],"expressed":[22,86,100,127,148,187,208],"located":[26,64],"the":[28,31,48,57,66,91,102,133,146,149,158,164,196,210,214,217,221,228,236,240,243,277],"mucosa":[29,93,147,215,241],"stomach":[32,58,92,134],"WB(-)+/+":[34],"and":[35,78,230,261,266,273],"(WB":[36],"x":[37],"C57BL/6)F1(-)+/+":[38],"(hereafter":[39],"WBB6F1(-)+/+)":[40],"mice":[41,97,125,185],"but":[42,98,152],"not":[43,70,85,193,226],"same":[49],"tissue":[50,271],"C57BL/":[52],"6(-)+/+":[53],"mice.":[54,140,201,248],"Even":[55],"WBB6F1(-)+/+":[60,96,124,184],"mice,":[61],"muscularis":[67,159,197,218,244],"propria":[68,160,198,245],"did":[69,161,192,225],"express":[71],"MMCP-2":[72,110,128,150,188,203],"mRNA.":[73],"mRNAs":[75],"MMCP-4":[77,229],"mouse":[79],"carboxypeptidase":[82],"A":[83],"were":[84,99,130],"untreated":[95],"after":[101,209,235],"infection":[103,275],"Strongyloides":[105],"venezuelensis.":[106],"We":[107],"examined":[108],"whether":[109],"varied":[113],"changing":[115],"environments":[116],"cells.":[119],"Cultured":[120],"that":[126,143,155,186,253],"transplanted":[131],"into":[132,170],"wall":[135],"genetically":[137],"mast-cell-deficient":[138],"WBB6F1(-)W/Wv":[139],"Mast":[141],"appeared":[144,156],"mRNA,":[151],"not,":[162],"indicating":[163],"adaptation":[165],"cultured":[167,177],"a":[171],"new":[172],"environment.":[173],"In":[174],"contrast":[175],"to":[176,195,206],"cells,":[179],"peritoneal":[180,222],"as":[190,258,270],"well":[191],"adapt":[194],"WBB6F(1)-W/Wv":[200,247],"remained":[205],"be":[207],"settlement":[211,237],"either":[213,239],"or":[216,242],"propria.":[219],"Furthermore,":[220],"change":[227],"MMCP-6":[231],"present":[250],"result":[251],"indicated":[252],"both":[254],"intracellular":[255],"factors":[256,268],"such":[257,269],"strain":[259],"specificity":[260,272],"source":[262],"extracellular":[267],"helminth":[274],"influenced":[276],"phenotypes.":[280]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}