{"id":"https://openalex.org/W97944388","doi":"https://doi.org/10.22029/eir.2005.1619","title":"Paediatric exercise immunology: Health and clinical applications","display_name":"Paediatric exercise immunology: Health and clinical applications","publication_year":2026,"publication_date":"2026-07-15","ids":{"openalex":"https://openalex.org/W97944388","doi":"https://doi.org/10.22029/eir.2005.1619","mag":"97944388","pmid":"https://pubmed.ncbi.nlm.nih.gov/16385848"},"language":"en","primary_location":{"id":"pmid:16385848","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16385848","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Exercise immunology review","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["datacite","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://doi.org/10.22029/eir.2005.1619","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062918564","display_name":"Brian Weldon Timmons","orcid":"https://orcid.org/0000-0002-4063-9656","observed_orcids":["https://orcid.org/0000-0002-4063-9656"]},"institutions":[{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Timmons, BW","raw_affiliation_strings":["Department of Paediatrics, McMaster University, Hamilton, ON, CANADA. timmonbw@mcmaster.ca"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Paediatrics, McMaster University, Hamilton, ON, CANADA. timmonbw@mcmaster.ca","institution_ids":["https://openalex.org/I98251732"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5062918564"],"corresponding_institution_ids":["https://openalex.org/I98251732"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.00020846,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"11","issue":null,"first_page":"108","last_page":"44"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11585","display_name":"Exercise and Physiological Responses","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10352","display_name":"Physical Activity and Health","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13770","display_name":"Pediatric health and respiratory diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/exercise-immunology","display_name":"exercise immunology","score":0.9309999942779541},{"id":"https://openalex.org/keywords/children-and-adolescents","display_name":"children and adolescents","score":0.703000009059906},{"id":"https://openalex.org/keywords/acute-exercise-effects","display_name":"acute exercise effects","score":0.6290000081062317},{"id":"https://openalex.org/keywords/exercise-training","display_name":"exercise training","score":0.8700000047683716}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7277170419692993},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.7205244302749634},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.6188881397247314},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.6114834547042847},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.49466368556022644},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.4699920415878296},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.38593411445617676},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1350959837436676},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.09601032733917236},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.07606309652328491},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000375","descriptor_name":"Aging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007107","descriptor_name":"Immune System","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D007109","descriptor_name":"Immunity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007239","descriptor_name":"Infections","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012737","descriptor_name":"Sex Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015444","descriptor_name":"Exercise","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmid:16385848","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16385848","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Exercise immunology review","raw_type":"Journal Article"},{"id":"doi:10.22029/eir.2005.1619","doi":"https://doi.org/10.22029/eir.2005.1619","is_oa":true,"landing_page_url":"https://doi.org/10.22029/eir.2005.1619","pdf_url":null,"source":{"id":"https://openalex.org/S7407052994","display_name":"Universit\u00e4tsbibliothek Gie\u00dfen","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I200763008","host_organization_name":"Justus-Liebig-Universit\u00e4t Gie\u00dfen","host_organization_lineage":["https://openalex.org/I200763008"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},{"id":"mag:97944388","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16385848","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"doi:10.22029/eir.2005.1619","doi":"https://doi.org/10.22029/eir.2005.1619","is_oa":true,"landing_page_url":"https://doi.org/10.22029/eir.2005.1619","pdf_url":null,"source":{"id":"https://openalex.org/S7407052994","display_name":"Universit\u00e4tsbibliothek Gie\u00dfen","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I200763008","host_organization_name":"Justus-Liebig-Universit\u00e4t Gie\u00dfen","host_organization_lineage":["https://openalex.org/I200763008"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"JournalArticle"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":189,"referenced_works":["https://openalex.org/W11486939","https://openalex.org/W31368529","https://openalex.org/W36584949","https://openalex.org/W68068221","https://openalex.org/W79586525","https://openalex.org/W98044644","https://openalex.org/W112684433","https://openalex.org/W189509291","https://openalex.org/W190052799","https://openalex.org/W240905192","https://openalex.org/W573789808","https://openalex.org/W604943240","https://openalex.org/W1492253807","https://openalex.org/W1494122660","https://openalex.org/W1521558739","https://openalex.org/W1556342164","https://openalex.org/W1572741274","https://openalex.org/W1574544452","https://openalex.org/W1733999086","https://openalex.org/W1840622518","https://openalex.org/W1887628684","https://openalex.org/W1951532834","https://openalex.org/W1963912609","https://openalex.org/W1964708707","https://openalex.org/W1965034038","https://openalex.org/W1965450725","https://openalex.org/W1967964669","https://openalex.org/W1970749999","https://openalex.org/W1970856648","https://openalex.org/W1971794277","https://openalex.org/W1972763246","https://openalex.org/W1973791283","https://openalex.org/W1974033843","https://openalex.org/W1975456996","https://openalex.org/W1975514273","https://openalex.org/W1975747142","https://openalex.org/W1975797028","https://openalex.org/W1979454503","https://openalex.org/W1981922506","https://openalex.org/W1983312490","https://openalex.org/W1986137024","https://openalex.org/W1986841296","https://openalex.org/W1988308110","https://openalex.org/W1988501271","https://openalex.org/W1989287758","https://openalex.org/W1989394723","https://openalex.org/W1989764604","https://openalex.org/W1990370622","https://openalex.org/W1991390542","https://openalex.org/W1991984962","https://openalex.org/W1992242288","https://openalex.org/W1995279445","https://openalex.org/W1996746152","https://openalex.org/W1997856503","https://openalex.org/W1998157374","https://openalex.org/W1998805591","https://openalex.org/W2001829958","https://openalex.org/W2001955029","https://openalex.org/W2003398515","https://openalex.org/W2005198842","https://openalex.org/W2005879474","https://openalex.org/W2006054056","https://openalex.org/W2006618315","https://openalex.org/W2007823865","https://openalex.org/W2011197389","https://openalex.org/W2011882150","https://openalex.org/W2017579559","https://openalex.org/W2018294582","https://openalex.org/W2018905379","https://openalex.org/W2020211182","https://openalex.org/W2023561026","https://openalex.org/W2024366071","https://openalex.org/W2024681203","https://openalex.org/W2024936000","https://openalex.org/W2026784736","https://openalex.org/W2027160253","https://openalex.org/W2028362346","https://openalex.org/W2029143718","https://openalex.org/W2030289876","https://openalex.org/W2032404560","https://openalex.org/W2033124959","https://openalex.org/W2035606954","https://openalex.org/W2036082570","https://openalex.org/W2037503665","https://openalex.org/W2038869287","https://openalex.org/W2041671143","https://openalex.org/W2045080859","https://openalex.org/W2045808998","https://openalex.org/W2047785202","https://openalex.org/W2050770535","https://openalex.org/W2052790450","https://openalex.org/W2053694100","https://openalex.org/W2055709688","https://openalex.org/W2056022494","https://openalex.org/W2056735941","https://openalex.org/W2064511809","https://openalex.org/W2066160102","https://openalex.org/W2066606737","https://openalex.org/W2066730617","https://openalex.org/W2067085553","https://openalex.org/W2067262787","https://openalex.org/W2068395655","https://openalex.org/W2070377185","https://openalex.org/W2072111883","https://openalex.org/W2075163403","https://openalex.org/W2075826908","https://openalex.org/W2077628724","https://openalex.org/W2077741425","https://openalex.org/W2078083987","https://openalex.org/W2078910425","https://openalex.org/W2079367547","https://openalex.org/W2082164878","https://openalex.org/W2083670227","https://openalex.org/W2084882993","https://openalex.org/W2085866717","https://openalex.org/W2087818277","https://openalex.org/W2091759034","https://openalex.org/W2093848042","https://openalex.org/W2097255040","https://openalex.org/W2098176136","https://openalex.org/W2099019634","https://openalex.org/W2099159352","https://openalex.org/W2099265019","https://openalex.org/W2107727063","https://openalex.org/W2109141141","https://openalex.org/W2111074957","https://openalex.org/W2112586160","https://openalex.org/W2112918049","https://openalex.org/W2112978990","https://openalex.org/W2114055381","https://openalex.org/W2114280375","https://openalex.org/W2115197006","https://openalex.org/W2115421619","https://openalex.org/W2115556861","https://openalex.org/W2115594368","https://openalex.org/W2119473993","https://openalex.org/W2121355580","https://openalex.org/W2122185430","https://openalex.org/W2124475955","https://openalex.org/W2126545477","https://openalex.org/W2127647469","https://openalex.org/W2129456294","https://openalex.org/W2130248772","https://openalex.org/W2132607881","https://openalex.org/W2134739399","https://openalex.org/W2134802533","https://openalex.org/W2135240313","https://openalex.org/W2140602955","https://openalex.org/W2140671814","https://openalex.org/W2147623166","https://openalex.org/W2150395635","https://openalex.org/W2153172400","https://openalex.org/W2154746915","https://openalex.org/W2158153849","https://openalex.org/W2162400367","https://openalex.org/W2162650059","https://openalex.org/W2163712919","https://openalex.org/W2167880402","https://openalex.org/W2167965659","https://openalex.org/W2168755719","https://openalex.org/W2171079661","https://openalex.org/W2171534906","https://openalex.org/W2172067486","https://openalex.org/W2172133801","https://openalex.org/W2175856164","https://openalex.org/W2188973532","https://openalex.org/W2192753375","https://openalex.org/W2265227099","https://openalex.org/W2280762728","https://openalex.org/W2285204915","https://openalex.org/W2300927548","https://openalex.org/W2313202310","https://openalex.org/W2316239013","https://openalex.org/W2321219904","https://openalex.org/W2330083381","https://openalex.org/W2331172611","https://openalex.org/W2331706270","https://openalex.org/W2339972399","https://openalex.org/W2340294221","https://openalex.org/W2403583310","https://openalex.org/W2404452517","https://openalex.org/W2405425537","https://openalex.org/W2409504115","https://openalex.org/W2409788180","https://openalex.org/W2410145792","https://openalex.org/W2419012657","https://openalex.org/W2428889241","https://openalex.org/W2477186748","https://openalex.org/W4321001342"],"related_works":["https://openalex.org/W1974428288","https://openalex.org/W2188973532","https://openalex.org/W4386136466","https://openalex.org/W4416828989","https://openalex.org/W6887698257","https://openalex.org/W4387232359","https://openalex.org/W4388971573","https://openalex.org/W4230540949","https://openalex.org/W403967813","https://openalex.org/W2192753375"],"abstract_inverted_index":{"Considerable":[0],"advances":[1],"have":[2,151],"been":[3,153],"made":[4],"in":[5,65,82,102,118,146,177,184,200],"exercise":[6,60,87,97,142,144,205,225],"immunology":[7,88,226],"over":[8],"the":[9,21,35,44,54,62,79,83,99,115,132,178,201,208,216],"last":[10],"two":[11],"decades,":[12],"and":[13,50,58,61,89,98,104,126,149,155,182,207,221],"it":[14],"is":[15,76,157],"becoming":[16],"evident":[17],"that":[18,163],"many":[19],"of":[20,24,34,40,53,73,85,124,131,140,168,180,188,203,211],"health":[22,103,220],"benefits":[23,210],"regular":[25],"physical":[26,170,213],"activity":[27,171],"may":[28],"be":[29],"directly":[30],"related":[31],"to":[32,43,77,90,96,114,120,161,165],"activation":[33],"immune":[36,63,100,116,133,138,195],"system.":[37],"The":[38,71,137],"number":[39,187],"investigations":[41],"devoted":[42],"paediatric":[45,86,189,224],"population,":[46],"however,":[47],"remains":[48],"low,":[49],"our":[51],"understanding":[52],"interaction":[55],"between":[56,218],"acute":[57,122,204],"chronic":[59,141],"system":[64,101,117,134],"youth":[66],"is,":[67],"therefore,":[68],"relatively":[69],"deficient.":[70],"purpose":[72],"this":[74],"review":[75],"disseminate":[78],"existing":[80],"knowledge":[81],"area":[84,230],"discuss":[91],"growth-related":[92],"issues":[93],"with":[94,174],"respect":[95],"disease.":[105],"In":[106],"general,":[107],"healthy":[108,147],"children":[109,148],"experience":[110],"smaller":[111],"overall":[112],"perturbations":[113],"response":[119],"an":[121],"bout":[123],"exercise,":[125],"demonstrate":[127],"a":[128,175,193,228],"faster":[129],"recovery":[130],"following":[135],"exercise.":[136],"effects":[139,206],"and/or":[143],"training":[145],"adolescents":[150],"not":[152],"well-documented,":[154],"there":[156],"only":[158],"limited":[159],"evidence":[160],"suggest":[162],"moderate":[164],"high":[166],"levels":[167],"habitual":[169],"are":[172,197],"associated":[173],"reduction":[176],"incidence":[179],"infection":[181],"illness":[183],"youth.":[185],"A":[186],"clinical":[190],"conditions":[191],"expressing":[192],"strong":[194],"component":[196],"also":[198],"discussed":[199],"context":[202],"potential":[209],"enhanced":[212],"activity.":[214],"Given":[215],"linkage":[217],"childhood":[219],"adult":[222],"disease,":[223],"represents":[227],"fruitful":[229],"for":[231],"future":[232],"study.":[233]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
