{"id":"https://openalex.org/W971327296","doi":null,"title":"Caracteriza\u00e7\u00e3o bioqu\u00edmica, din\u00e2mica molecular e propriedades imunomoduladoras da prolil oligopeptidase de Mycobacterium tuberculosis","display_name":"Caracteriza\u00e7\u00e3o bioqu\u00edmica, din\u00e2mica molecular e propriedades imunomoduladoras da prolil oligopeptidase de Mycobacterium tuberculosis","publication_year":2014,"publication_date":"2014-11-11","ids":{"openalex":"https://openalex.org/W971327296","mag":"971327296"},"language":"pt","primary_location":{"id":"pmh:oai:americanae.aecid.es:1823458","doi":null,"is_oa":false,"landing_page_url":"http://repositorio.unb.br/handle/10482/16840","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da UnB","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5062123538","display_name":"Brina Portugal","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Brina Portugal","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5062123538"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.489300012588501,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology","score":0.489300012588501,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12505","display_name":"Peptidase Inhibition and Analysis","score":0.24889999628067017,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11103","display_name":"Antimicrobial Peptides and Activities","score":0.034299999475479126,"subfield":{"id":"https://openalex.org/subfields/2404","display_name":"Microbiology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mycobacterium-tuberculosis","display_name":"Mycobacterium tuberculosis","score":0.996999979019165},{"id":"https://openalex.org/keywords/biochemical-characterization","display_name":"biochemical characterization","score":0.8140000104904175},{"id":"https://openalex.org/keywords/molecular-dynamics","display_name":"molecular dynamics","score":0.871999979019165},{"id":"https://openalex.org/keywords/immunomodulation","display_name":"immunomodulation","score":0.8899999856948853},{"id":"https://openalex.org/keywords/host-pathogen-interaction","display_name":"host-pathogen interaction","score":0.7940000295639038},{"id":"https://openalex.org/keywords/protease","display_name":"proteolytic enzymes","score":0.6449999809265137}],"concepts":[{"id":"https://openalex.org/C2781038479","wikidata":"https://www.wikidata.org/wiki/Q114675","display_name":"Mica","level":2,"score":0.8591139316558838},{"id":"https://openalex.org/C2777975735","wikidata":"https://www.wikidata.org/wiki/Q130971","display_name":"Mycobacterium tuberculosis","level":3,"score":0.7610018253326416},{"id":"https://openalex.org/C2781069245","wikidata":"https://www.wikidata.org/wiki/Q12204","display_name":"Tuberculosis","level":2,"score":0.518416166305542},{"id":"https://openalex.org/C2780043585","wikidata":"https://www.wikidata.org/wiki/Q7086841","display_name":"Oligopeptidase","level":3,"score":0.4377667009830475},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.40018609166145325},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.3792349100112915},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.3753759264945984},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2747894525527954},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20577585697174072},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.13369089365005493},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.10274812579154968},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.055649906396865845},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:americanae.aecid.es:1823458","doi":null,"is_oa":false,"landing_page_url":"http://repositorio.unb.br/handle/10482/16840","pdf_url":null,"source":{"id":"https://openalex.org/S4306400786","display_name":"Americanae (AECID Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"reponame:Reposit\u00f3rio Institucional da UnB","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:repositorio.unb.br:10482/16840","doi":null,"is_oa":false,"landing_page_url":"http://repositorio.unb.br/handle/10482/16840","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"instacron:UNB","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"pmh:oai:repositorio2.unb.br:10482/16840","doi":null,"is_oa":false,"landing_page_url":"http://repositorio.unb.br/handle/10482/16840","pdf_url":null,"source":{"id":"https://openalex.org/S4377196379","display_name":"RIUnB Institutional Repository (University of Bras\u00edlia)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I150729083","host_organization_name":"Universidade de Bras\u00edlia","host_organization_lineage":["https://openalex.org/I150729083"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Tese"},{"id":"mag:971327296","doi":null,"is_oa":false,"landing_page_url":"https://repositorio.unb.br/bitstream/10482/16840/1/2014_BrinaPortugal.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.504800021648407}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":185,"referenced_works":["https://openalex.org/W73894140","https://openalex.org/W629090243","https://openalex.org/W1008198766","https://openalex.org/W1491824558","https://openalex.org/W1508885706","https://openalex.org/W1515177138","https://openalex.org/W1550745757","https://openalex.org/W1574813722","https://openalex.org/W1591852988","https://openalex.org/W1600900121","https://openalex.org/W1605208918","https://openalex.org/W1617649427","https://openalex.org/W1764151989","https://openalex.org/W1764515802","https://openalex.org/W1814964070","https://openalex.org/W1821584526","https://openalex.org/W1836918009","https://openalex.org/W1847996750","https://openalex.org/W1848808032","https://openalex.org/W1861216681","https://openalex.org/W1893039775","https://openalex.org/W1904782847","https://openalex.org/W1923641765","https://openalex.org/W1952065778","https://openalex.org/W1965395493","https://openalex.org/W1969398979","https://openalex.org/W1969432608","https://openalex.org/W1969948291","https://openalex.org/W1970164033","https://openalex.org/W1970570244","https://openalex.org/W1972108395","https://openalex.org/W1973214902","https://openalex.org/W1974411204","https://openalex.org/W1974645020","https://openalex.org/W1977479698","https://openalex.org/W1978839885","https://openalex.org/W1980219296","https://openalex.org/W1981172688","https://openalex.org/W1981207136","https://openalex.org/W1982300532","https://openalex.org/W1984243890","https://openalex.org/W1987534021","https://openalex.org/W1987604884","https://openalex.org/W1988291102","https://openalex.org/W1990070939","https://openalex.org/W1996911908","https://openalex.org/W1997886489","https://openalex.org/W1998676514","https://openalex.org/W1999107098","https://openalex.org/W1999264959","https://openalex.org/W1999374389","https://openalex.org/W2003415517","https://openalex.org/W2004694654","https://openalex.org/W2007961360","https://openalex.org/W2008961537","https://openalex.org/W2009972285","https://openalex.org/W2010268195","https://openalex.org/W2011128355","https://openalex.org/W2017038699","https://openalex.org/W2017290044","https://openalex.org/W2020535330","https://openalex.org/W2020689975","https://openalex.org/W2022852642","https://openalex.org/W2023478821","https://openalex.org/W2023920446","https://openalex.org/W2024239571","https://openalex.org/W2027345286","https://openalex.org/W2029077665","https://openalex.org/W2029667189","https://openalex.org/W2033548785","https://openalex.org/W2035507375","https://openalex.org/W2035634351","https://openalex.org/W2035687084","https://openalex.org/W2035847639","https://openalex.org/W2036158102","https://openalex.org/W2036700120","https://openalex.org/W2036869932","https://openalex.org/W2040595488","https://openalex.org/W2041053833","https://openalex.org/W2043340061","https://openalex.org/W2043432881","https://openalex.org/W2044680438","https://openalex.org/W2045668077","https://openalex.org/W2045857220","https://openalex.org/W2051831487","https://openalex.org/W2052067496","https://openalex.org/W2053991753","https://openalex.org/W2054596311","https://openalex.org/W2055264790","https://openalex.org/W2058170527","https://openalex.org/W2058677329","https://openalex.org/W2060871750","https://openalex.org/W2062408667","https://openalex.org/W2062919894","https://openalex.org/W2065721264","https://openalex.org/W2066135800","https://openalex.org/W2066503688","https://openalex.org/W2067174909","https://openalex.org/W2067307549","https://openalex.org/W2072555826","https://openalex.org/W2074631079","https://openalex.org/W2075000963","https://openalex.org/W2075105102","https://openalex.org/W2077540472","https://openalex.org/W2078978659","https://openalex.org/W2079288441","https://openalex.org/W2079722764","https://openalex.org/W2081589091","https://openalex.org/W2082628662","https://openalex.org/W2083699890","https://openalex.org/W2087187487","https://openalex.org/W2088560909","https://openalex.org/W2090852407","https://openalex.org/W2090941537","https://openalex.org/W2092523176","https://openalex.org/W2093155820","https://openalex.org/W2093423705","https://openalex.org/W2094389347","https://openalex.org/W2095274534","https://openalex.org/W2097817417","https://openalex.org/W2100091027","https://openalex.org/W2100531445","https://openalex.org/W2102628698","https://openalex.org/W2103945336","https://openalex.org/W2104237442","https://openalex.org/W2104941073","https://openalex.org/W2105243809","https://openalex.org/W2107095526","https://openalex.org/W2107928498","https://openalex.org/W2108500436","https://openalex.org/W2108961981","https://openalex.org/W2109827218","https://openalex.org/W2113403117","https://openalex.org/W2114308840","https://openalex.org/W2114520383","https://openalex.org/W2114522205","https://openalex.org/W2114734298","https://openalex.org/W2116611990","https://openalex.org/W2118822326","https://openalex.org/W2119603196","https://openalex.org/W2126744631","https://openalex.org/W2128158122","https://openalex.org/W2128287837","https://openalex.org/W2128572087","https://openalex.org/W2130479394","https://openalex.org/W2135922389","https://openalex.org/W2137144551","https://openalex.org/W2140354550","https://openalex.org/W2142943034","https://openalex.org/W2143296217","https://openalex.org/W2143537616","https://openalex.org/W2143989921","https://openalex.org/W2144010669","https://openalex.org/W2147951828","https://openalex.org/W2149181646","https://openalex.org/W2150983434","https://openalex.org/W2151738661","https://openalex.org/W2153001182","https://openalex.org/W2156093675","https://openalex.org/W2157492674","https://openalex.org/W2157737997","https://openalex.org/W2158023121","https://openalex.org/W2158658436","https://openalex.org/W2158714788","https://openalex.org/W2158888521","https://openalex.org/W2160452309","https://openalex.org/W2160555964","https://openalex.org/W2162146381","https://openalex.org/W2165412123","https://openalex.org/W2166668583","https://openalex.org/W2169423236","https://openalex.org/W2170913968","https://openalex.org/W2171734128","https://openalex.org/W2183033664","https://openalex.org/W2187159861","https://openalex.org/W2227672922","https://openalex.org/W2319488848","https://openalex.org/W2322531466","https://openalex.org/W2329720797","https://openalex.org/W2396632380","https://openalex.org/W2398495384","https://openalex.org/W2418118908","https://openalex.org/W2883755802","https://openalex.org/W3197187231","https://openalex.org/W4381544074"],"related_works":["https://openalex.org/W7120738177","https://openalex.org/W2509609693","https://openalex.org/W7120676149","https://openalex.org/W2970331432","https://openalex.org/W3151392711","https://openalex.org/W2586205336","https://openalex.org/W1531544781","https://openalex.org/W7037083251","https://openalex.org/W7046985571","https://openalex.org/W7026587552"],"abstract_inverted_index":{"Tese":[0],"(doutorado)\u2014Universidade":[1],"de":[2,5,8,14],"Bras\u00edlia,":[3],"Faculdade":[4],"Medicina,":[6],"Programa":[7],"P\u00f3s-Gradua\u00e7\u00e3o":[9],"em":[10],"Patologia":[11],"Molecular,":[12],"Laborat\u00f3rio":[13],"Intera\u00e7\u00e3o":[15],"Pat\u00f3geno-Hospedeiro,":[16],"2014.":[17]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2016-06-24T00:00:00"}